🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Mrinal Shekhar

Broad Institute

ORCID: 0000-0001-8089-8858

Also affiliated with Foundation for the National Institutes of Health

Biochemistry, Genetics and Molecular BiologyMaterials Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile
1.2Author DataRank

Indexed papers

2in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge

Nature Methods(2024)10.1038/s41592-024-02321-7
Top 23%
0.871DataRank
Top 23%18 citations

Andriy Kryshtafovych, Grigore Pintilie, S.K. Burley, Jiri Cerny, Vincent B. Chen +76 more

Papers

Driven by 17 papers — median percentile 64. Top paper: “High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter”.

High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter

eLife(2023)10.7554/elife.84006
N/A
1.3DataRank · unranked
44 citations

Samuel P. Berry, Eric Wilson, Casey H. Zhang, Mrinal Shekhar, Abhishek Singharoy +2 more

Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge

Nature Methods(2024)10.1038/s41592-024-02321-7
Top 23%
0.871DataRank
Top 23%18 citations

Andriy Kryshtafovych, Grigore Pintilie, S.K. Burley, Jiri Cerny, Vincent B. Chen +76 more

Outcomes of the 2019 EMDataResource model challenge: validation of cryo-EM models at near-atomic resolution

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.12.147033
Top 48%
0.375DataRank
Top 48%7 citations

Andriy Kryshtafovych, Paul D. Adams, Pavel V. Afonine, Matthew L. Baker, Benjamin A. Barad +49 more

XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia

Structure(2020)10.1016/j.str.2020.02.005
N/A
0DataRank · unranked
12 citations

Mrinal Shekhar, Debra T. Hansen, Chelsie E. Conrad, Thomas D. Grant, Chitrak Gupta +24 more

Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.03.023564
N/A
0DataRank · unranked
7 citations

Chloé Martens, Mrinal Shekhar, Shashank Pant, Grant A. Pellowe, Andy M. Lau +6 more

Cryo-EM model validation recommendations based on outcomes of the 2019 EMDataResource challenge

Nature Methods(2021)10.1038/s41592-020-01051-w
N/A
0DataRank · unranked
119 citations

Andriy Kryshtafovych, Paul D. Adams, Pavel V. Afonine, Matthew L. Baker, Benjamin A. Barad +49 more

CryoFold: Determining protein structures and data-guided ensembles from cryo-EM density maps

Matter(2021)10.1016/j.matt.2021.09.004
N/A
0DataRank · unranked
51 citations

Genki Terashi, Chitrak Gupta, Daipayan Sarkar, Gaspard Debussche, Nicholas J. Sisco +11 more

Protein Flexibility and Dissociation Pathway Differentiation Can Explain Onset of Resistance Mutations in Kinases**

Angewandte Chemie International Edition(2022)10.1002/anie.202200983
N/A
0DataRank · unranked
51 citations

Zachary Smith, Markus A. Seeliger, Pratyush Tiwary, Mrinal Shekhar

High-resolution structures map the metal import pathway in an Nramp transporter

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.08.507188
N/A
0DataRank · unranked
2 citations

Samuel P. Berry, Eric Wilson, Casey H. Zhang, Mrinal Shekhar, Abhishek Singharoy +2 more

Target-driven machine learning-enabled virtual screening (TAME-VS) platform for early-stage hit identification

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2023.1163536
N/A
0DataRank · unranked
7 citations

Jason J. Kwon, Cong Liu, Enrico Margiotta, Mrinal Shekhar, Alexandra E. Gould +1 more

Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance

Cell(2024)10.1016/j.cell.2024.07.048
N/A
0DataRank · unranked
23 citations

Junhua Pan, Pan Yang, Yuemin Bian, Gábor Oroszlán, Zishuo Yu +7 more

Outcomes of the EMDataResource Cryo-EM Ligand Modeling Challenge

Research Square(2024)10.21203/rs.3.rs-3864137/v1
N/A
0DataRank · unranked
2 citations

Andriy Kryshtafovych, Grigore Pintilie, S.K. Burley, Jiri Cerny, Vincent Chen +76 more

Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly

Cell(2025)10.1016/j.cell.2025.11.041
N/A
0DataRank · unranked
3 citations

Pradeep Sathyanarayana, Cong Liu, Joel M. J. Tan, Pan pan Yang, Biswajit Das +10 more

Retrieving functional pathways of biomolecules from single-particle snapshots

Nature Communications(2020)10.1038/s41467-020-18403-x
N/A
0DataRank · unranked
111 citations

Ghoncheh Mashayekhi, Mrinal Shekhar, Danya Ben-Hail, Salah Salah, Peter Schwander +5 more

Mechanisms of HSV-1 helicase–primase inhibition and replication fork complex assembly

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.23.696259
N/A
0DataRank · unranked
0 citations

Pradeep Sathyanarayana, Cong Liu, Pan pan Yang, Sandra K. Weller, Mrinal Shekhar +4 more

Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter

Nature Communications(2020)10.1038/s41467-020-20032-3
N/A
0DataRank · unranked
83 citations

Chloé Martens, Mrinal Shekhar, Shashank Pant, Grant A. Pellowe, Andy M. Lau +6 more

Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex

Science Advances(2020)10.1126/sciadv.abb9605
N/A
0DataRank · unranked
77 citations

Mrinal Shekhar, Grigore Pintilie, Christophe Chipot, Stephan Wilkens, Abhishek Singharoy +2 more