Todd C. Holmes

Neuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.269Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Multiscale Spatial Transcriptomic Atlas of Human Basal Ganglia Cell-Type and Cellular Community Organization

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.02.691876

Top 70%

0.165DataRank

Top 70%2 citations

Zhiqun Tan, Ginny Wu, Sujan C. Das, Li Ren, Benjamin Esser +16 more

Papers

Driven by 42 papers — median percentile 26. Top paper: “Microglia Elimination Increases Neural Circuit Connectivity and Activity in Adult Mouse Cortex”.

Microglia Elimination Increases Neural Circuit Connectivity and Activity in Adult Mouse Cortex

Journal of Neuroscience(2020)10.1523/jneurosci.2140-20.2020

N/A

0.768DataRank · unranked

166 citations

Elizabeth E. Spangenberg, Bryan Y. Tang, Todd C. Holmes, Kim N. Green, Xiangmin Xu +1 more

Subanesthetic ketamine reactivates adult cortical plasticity to restore vision from amblyopia

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.16.994475

N/A

0.630DataRank · unranked

14 citations

Xin Qiao, Xiaoting Zheng, Yong‐Jun Liu, Lujia Chen, Hai Zhang +6 more

Noncanonical projections to the hippocampal CA3 regulate spatial learning and memory by modulating the feedforward hippocampal trisynaptic pathway

PLoS Biology(2021)10.1371/journal.pbio.3001127

N/A

0.564DataRank · unranked

42 citations

Michelle Amalraj, Crisylle Blanton, Brenda Avila, Todd C. Holmes, Douglas A. Nitz +2 more

Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing

Neurobiology of Disease(2022)10.1016/j.nbd.2022.105820

N/A

0.524DataRank · unranked

32 citations

Gocylen Gast, Xilin Su, Takashi Saito, Takaomi C. Saido, Todd C. Holmes +2 more

Nocturnal mosquito Cryptochrome 1 mediates greater electrophysiological and behavioral responses to blue light relative to diurnal mosquito Cryptochrome 1

Frontiers in Neuroscience(2022)10.3389/fnins.2022.1042508

N/A

0.292DataRank · unranked

6 citations

Jenny C. Liu, Thanh H. Nguyen, Alexander J Foden, Soo Jee Park, Mia Dimalanta +3 more

Octodon degus laboratory colony management principles and methods for behavioral analysis for Alzheimer’s disease neuroscience research

Frontiers in Aging Neuroscience(2025)10.3389/fnagi.2024.1517416

N/A

0.241DataRank · unranked

4 citations

Todd C. Holmes, Robert M. J. Deacon, Xiangmin Xu, Patricia Cogram, B. Maximiliano Garduño

Multiscale Spatial Transcriptomic Atlas of Human Basal Ganglia Cell-Type and Cellular Community Organization

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.02.691876

Top 70%

0.165DataRank

Top 70%2 citations

Zhiqun Tan, Ginny Wu, Sujan C. Das, Li Ren, Benjamin Esser +16 more

Hippocampal neural circuit mechanisms in Alzheimer's disease revealed by viral-genetic circuit mapping

Neurobiology of Disease(2025)10.1016/j.nbd.2025.107139

N/A

0.104DataRank · unranked

1 citations

Gocylen Gast, Todd C. Holmes, Xiangmin Xu, Qiao Ye

UC Irvine’s Brain Initiative Cell Atlas Network (BICAN) Brain Procurement Program for the Center for Multiomic Human Brain Cell Atlas Project

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.23.696304

Top 78%

0.104DataRank

Top 78%1 citations

Bryan M Tran, Ginny Wu, Zhiqun Tan, Elizabeth Mendoza, Miyoung Kim +44 more

Non-Canonical Projections from Ventral CA1 and Subicular Complex to CA3 Augments the Feedforward Hippocampal Trisynaptic Pathway

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.01.429124

N/A

0DataRank · unranked

4 citations

Michelle Amalraj, Crisylle Blanton, Brenda Avila, Todd C. Holmes, Douglas A. Nitz +2 more

Spatial coding defects of hippocampal neural ensemble calcium activities in the 3xTg-AD Alzheimer’s disease mouse model

Research Square(2021)10.21203/rs.3.rs-550358/v1

N/A

0DataRank · unranked

0 citations

Lujia Chen, David Baglietto‐Vargas, Qiao Ye, Frank M. LaFerla, Douglas A. Nitz +3 more

Psychedelics and Neural Plasticity: Therapeutic Implications

Journal of Neuroscience(2022)10.1523/jneurosci.1121-22.2022

N/A

0DataRank · unranked

86 citations

Eero Ċastrén, Gitte M. Knudsen, Alex C. Kwan, David E. Olson, Yi Zuo +3 more

Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease

Neurobiology of Disease(2022)10.1016/j.nbd.2022.105939

N/A

0DataRank · unranked

23 citations

Lujia Chen, Kevin G. Johnston, Joshua Crapser, Kim N. Green, Nicole My-Linh Ha +5 more

Longitudinal dynamics of microvascular recovery after acquired cortical injury

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01361-4

N/A

0DataRank · unranked

17 citations

Lujia Chen, Amandine Jullienne, Hai Zhang, Arjang Salehi, Mary Hamer +4 more

Genome Sequencing Variations in the Octodon degus, an Unconventional Natural Model of Aging and Alzheimer's Disease

Frontiers in Aging Neuroscience(2022)10.3389/fnagi.2022.894994

N/A

0DataRank · unranked

14 citations

Claudio Urra, B. Maximiliano Garduño, Agostino Bruno, Allison Kimbell, Brent Wilkinson +18 more

Mitochondrial LETM1 drives ionic and molecular clock rhythms in circadian pacemaker neurons

Cell Reports(2022)10.1016/j.celrep.2022.110787

N/A

0DataRank · unranked

14 citations

Yusuke Kasuga, Yuzuki Kanda, Saki Moritama, Hayato Koizumi, T. Yoshikawa +6 more

Commentary: How Do Microglia Regulate Neural Circuit Connectivity and Activity in the Adult Brain?

Neuroscience Insights(2022)10.1177/26331055211071124

N/A

0DataRank · unranked

5 citations

Kim N. Green, Todd C. Holmes, Xiangmin Xu, Yong‐Jun Liu

Longitudinal dynamics of microvascular recovery after acquired cortical injury

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.09.483613

N/A

0DataRank · unranked

1 citations

Lujia Chen, Amandine Jullienne, Hai Zhang, Arjang Salehi, Mary Hamer +4 more

Erythrocyte–brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo

Journal of Neuroinflammation(2023)10.1186/s12974-023-02932-5

N/A

0DataRank · unranked

21 citations

Rachita K. Sumbria, Rudy Chang, Jiahong Sun, David H. Cribbs, Todd C. Holmes +3 more

Probing neural circuit mechanisms in Alzheimer’s disease using novel technologies

Molecular Psychiatry(2023)10.1038/s41380-023-02018-x

N/A

0DataRank · unranked

29 citations

Todd C. Holmes, Xiangmin Xu, Steven F. Grieco

Anatomical and molecular characterization of parvalbumin-cholecystokinin co-expressing inhibitory interneurons: implications for neuropsychiatric conditions

Molecular Psychiatry(2023)10.1038/s41380-023-02153-5

N/A

0DataRank · unranked

18 citations

Kevin G. Johnston, Pan Gao, B. Maximiliano Garduño, Bryan Y. Tang, Elsie Yi +6 more

Anatomical organization of temporally correlated neural calcium activity in the hippocampal CA1 region

iScience(2023)10.1016/j.isci.2023.106703

N/A

0DataRank · unranked

10 citations

Xiaoxiao Lin, Qiao Ye, Zoran Nenadić, Todd C. Holmes, Douglas A. Nitz +2 more

Drosophila photoreceptor systems converge in arousal neurons and confer light responsive robustness

Frontiers in Neuroscience(2023)10.3389/fnins.2023.1160353

N/A

0DataRank · unranked

4 citations

Jenny C. Liu, Soo Jee Park, Thanh H. Nguyen, Mia Dimalanta, Alexander J Foden +2 more

Hippocampal CA3 inhibitory neurons receive extensive noncanonical synaptic inputs from CA1 and subicular complex

The Journal of Comparative Neurology(2023)10.1002/cne.25510

N/A

0DataRank · unranked

5 citations

Neeyaz Cyrus, Brenda Avila, Todd C. Holmes, Xiangmin Xu, Xiaoxiao Lin

Intranasal Delivery of Ketamine Induces Cortical Disinhibition

eNeuro(2023)10.1523/eneuro.0107-23.2023

N/A

0DataRank · unranked

2 citations

Steven F. Grieco, Zhaoxia Yu, Todd C. Holmes, Xiangmin Xu, Xin Qiao

New rabies viral resources for multi-scale neural circuit mapping

Research Square(2023)10.21203/rs.3.rs-3250124/v1

N/A

0DataRank · unranked

0 citations

Alexis Bouin, Ginny Wu, Orkide Ö. Koyuncu, Qiao Ye, Keunyoung Kim +10 more

New rabies viral resources for multi-scale neural circuit mapping

Molecular Psychiatry(2024)10.1038/s41380-024-02451-6

N/A

0DataRank · unranked

15 citations

Ginny Wu, Orkide Ö. Koyuncu, Qiao Ye, Keunyoung Kim, Michele Wu +10 more

Monosynaptic rabies tracing reveals sex- and age-dependent dorsal subiculum connectivity alterations in an Alzheimer's disease mouse model

Journal of Neuroscience(2024)10.1523/jneurosci.1796-23.2024

N/A

0DataRank · unranked

9 citations

Gocylen Gast, Erik George Wilfley, Hanh Huynh, Chelsea C. Hays, Todd C. Holmes +2 more

Meeting report for the 2024 UC Irvine Center for neural circuit mapping conference: Brain cell types, circuits, and disorders

Molecular Psychiatry(2024)10.1038/s41380-024-02775-3

N/A

0DataRank · unranked

2 citations

Todd C. Holmes, Xiangmin Xu, Steven F. Grieco

Specific targeting of brain endothelial cells using enhancer AAV vectors

Neuron(2025)10.1016/j.neuron.2025.03.031

N/A

0DataRank · unranked

7 citations

Oyshi Dey, Nayoon S. Kim, Wenhao Cao, Qiao Ye, Pan Gao +9 more

An AAV capsid proposed as microglia-targeting directs genetic expression in forebrain excitatory neurons

Cell Reports Methods(2025)10.1016/j.crmeth.2025.101054

N/A

0DataRank · unranked

3 citations

Zhiqun Tan, Bereket T Berackey, Jason K. Nguyen, Sara R. Brown, Sheng Du +6 more

Unfolding neural diversity: how dynamic three-dimensional genome architecture regulates brain function and disease

Molecular Psychiatry(2025)10.1038/s41380-025-03056-3

N/A

0DataRank · unranked

4 citations

Steven F. Grieco, Todd C. Holmes, Xiangmin Xu, Brandon L. Logeman

Octodon degus: a natural animal model of aging and Alzheimer’s disease

Lab Animal(2025)10.1038/s41684-025-01602-8

N/A

0DataRank · unranked

1 citations

B. Maximiliano Garduño, Robert M. J. Deacon, Todd C. Holmes, Xiangmin Xu, Patricia Cogram +1 more

The innexin 7 gap junction protein contributes to synchronized activity in the Drosophila antennal lobe and regulates olfactory function

Frontiers in Neural Circuits(2025)10.3389/fncir.2025.1563401

N/A

0DataRank · unranked

0 citations

Sergio Hidalgo, Bryon Silva, Saurin Gandhi, Dung Thi Vo, Parham Zamani +7 more

Viral Vectors for Neural Circuit Mapping and Recent Advances in Trans-synaptic Anterograde Tracers

Neuron(2020)10.1016/j.neuron.2020.07.010

N/A

0DataRank · unranked

118 citations

Todd C. Holmes, Min‐Hua Luo, Kevin T. Beier, Gregory D. Horwitz, Fei Zhao +5 more

Circadian Regulation of Light-Evoked Attraction and Avoidance Behaviors in Daytime- versus Nighttime-Biting Mosquitoes

Current Biology(2020)10.1016/j.cub.2020.06.010

N/A

0DataRank · unranked

79 citations

Ceazar Nave, David D. Au, Tom Guda, Joshua A. Chevez, Anandasankar Ray +2 more

DrosophilaVoltage-Gated Sodium Channels Are Only Expressed in Active Neurons and Are Localized to Distal Axonal Initial Segment-like Domains

Journal of Neuroscience(2020)10.1523/jneurosci.0142-20.2020

N/A

0DataRank · unranked

76 citations

Jasper Janssens, Pei-Tseng Lee, Burak Tepe, Paul C. Marcogliese, Samira Makhzami +4 more

Robust Population Single Neuronal Calcium Signal Extraction Using SCOUT Allows for Longitudinal Analysis of Behavior-associated Neural Ensemble Dynamics

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.26.268151

N/A

0DataRank · unranked

5 citations

Steven F. Grieco, Zhaoxia Yu, Suoqin Jin, Tong Shen, Rachel Crary +4 more

Weekend light shifts evoke persistent Drosophila circadian neural network desynchrony

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2019.12.31.891507

N/A

0DataRank · unranked

1 citations

Logan Roberts, Patrick T. Hwu, Jerson D. Estrella, Thanh C. Vo, Thanh H. Nguyen +5 more

Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research

Neuron(2021)10.1016/j.neuron.2021.10.030

N/A

0DataRank · unranked

585 citations

Michele Guindani, Steven F. Grieco, Lujia Chen, Todd C. Holmes, Xiangmin Xu +1 more

Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model

Neurobiology of Disease(2021)10.1016/j.nbd.2021.105562

N/A

0DataRank · unranked

28 citations

Lujia Chen, David Baglietto‐Vargas, Parsa Kamalipour, Qiao Ye, Frank M. LaFerla +4 more

Neuregulin signaling mediates the acute and sustained antidepressant effects of subanesthetic ketamine

Translational Psychiatry(2021)10.1038/s41398-021-01255-4

N/A

0DataRank · unranked

26 citations

Xin Qiao, Kevin G. Johnston, Lujia Chen, Renetta R. Nelson, Cary Lai +3 more

Todd C. Holmes

Indexed papers

Top data-sharing exemplar

Papers