Ganesh A. Thakur

Also affiliated with Universidad del Noreste

Biochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 21 papers. Top paper: “Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation”.

Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation

Cell(2024)10.1016/j.cell.2024.01.032

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1.1DataRank · unranked

58 citations

Mariia Avstrikova, Colleen Noviello, Nuriya Mukhtasimova, Jean‐Pierre Changeux, Ganesh A. Thakur +4 more

GAT107-mediated α7 nicotinic acetylcholine receptor signaling attenuates inflammatory lung injury and mortality in a mouse model of ventilator-associated pneumonia by alleviating macrophage mitochondrial oxidative stress via reducing MnSOD-S-glutathionylation

Redox Biology(2023)10.1016/j.redox.2023.102614

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0.373DataRank · unranked

11 citations

Mosi Lin, Sidorela Zefi, Abhijit Kulkarni, Ganesh A. Thakur, Charles R. Ashby +2 more

Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116421

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0.373DataRank · unranked

11 citations

Peter C. Schaffer, Robert B. Laprairie, David R. Janero, Roger G. Pertwee, Alex Straiker +2 more

Stable desensitization of α7 nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site

European Journal of Pharmacology(2021)10.1016/j.ejphar.2021.174179

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0.312DataRank · unranked

7 citations

Nicole A. Horenstein, Clare Stokes, Clelia Dallanoce, Ganesh A. Thakur, Roger L. Papke +1 more

Differential Activation and Desensitization States Promoted by Noncanonical α 7 Nicotinic Acetylcholine Receptor Agonists

Journal of Pharmacology and Experimental Therapeutics(2022)10.1124/jpet.122.001354

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0.104DataRank · unranked

1 citations

Gisela Andrea Camacho‐Hernandez, Ganesh A. Thakur, Xiao-Xuan Wu, Palmer Taylor, Roger L. Papke +1 more

A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100535

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0DataRank · unranked

8 citations

Yaser Alhamshari, Lucas Cantwell, Said EI-Haou, Giasemi C. Eptaminitaki, Mengmeng Chang +10 more

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593

Frontiers in Pharmacology(2022)10.3389/fphar.2022.919605

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0DataRank · unranked

7 citations

Sumanta Garai, Ayat Zagzoog, Dow P. Hurst, Lesley Stevenson, Roger G. Pertwee +5 more

The type 1 cannabinoid receptor positive allosteric modulators GAT591 and GAT593 reduce spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg

IBRO Neuroscience Reports(2022)10.1016/j.ibneur.2022.01.006

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0DataRank · unranked

10 citations

Andrew J. Roebuck, Quentin Greba, Sumanta Garai, Asher L. Brandt, Orhan Yılmaz +6 more

Use of a Molecular Switch Probe to Activate or Inhibit GIRK1 Heteromers In Silico Reveals a Novel Gating Mechanism

International Journal of Molecular Sciences(2022)10.3390/ijms231810820

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0DataRank · unranked

7 citations

Lucas Cantwell, Yu Xu, Ganesh A. Thakur, Meng Cui, Frank Guarnieri +2 more

Explorations of Agonist Selectivity for the α9* nAChR with Novel Substituted Carbamoyl/Amido/Heteroaryl Dialkylpiperazinium Salts and Their Therapeutic Implications in Pain and Inflammation

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c02429

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0DataRank · unranked

9 citations

Roger L. Papke, Clare Stokes, Katrin Richter, Sara M Herz, Ka Chiang +7 more

Negative allosteric modulation of CB1 cannabinoid receptor signalling decreases intravenous morphine self‐administration and relapse in mice

Addiction Biology(2024)10.1111/adb.13429

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0DataRank · unranked

7 citations

Fezaan Kazi, Lucas Cantwell, Ganesh A. Thakur, Jonathon D. Crystal, Andrea G. Hohmann +1 more

Negative allosteric modulation of CB1 cannabinoid receptor signaling suppresses opioid-mediated tolerance and withdrawal without blocking opioid antinociception

Neuropharmacology(2024)10.1016/j.neuropharm.2024.110052

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0DataRank · unranked

8 citations

Shahin A. Saberi, Romario Pacheco, Emily Fender Sizemore, Sarah Stockman, Abhijit Kulkarni +4 more

New Alpha9 nAChR Ligands Based on a 5-(Quinuclidin-3-ylmethyl)-1,2,4-oxadiazole Scaffold

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.3c00720

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0DataRank · unranked

2 citations

Katrin Richter, Clare Stokes, Claudio Papotto, Hina Andleeb, Ganesh A. Thakur +4 more

Negative allosteric modulation of cannabinoid CB 1 receptor signaling suppresses opioid-mediated tolerance and withdrawal without blocking opioid antinociception

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.06.574477

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0DataRank · unranked

2 citations

Shahin A. Saberi, Romario Pacheco, Emily Fender Sizemore, Sarah Stockman, Abhijit Kulkarni +4 more

Negative allosteric modulation of CB1 cannabinoid receptor signaling decreases intravenous morphine self-administration and relapse in mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.16.575900

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0DataRank · unranked

2 citations

Fezaan Kazi, Lucas Cantwell, Ganesh A. Thakur, Jonathon D. Crystal, Andrea G. Hohmann +1 more

RIC3, the cholinergic anti-inflammatory pathway, and neuroinflammation

International Immunopharmacology(2020)10.1016/j.intimp.2020.106381

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0DataRank · unranked

19 citations

Sara Kagan, Hagit Cohen Ben-Ami, Jinar Rostami, Tehila Mizrahi, Abhijit Kulkarni +6 more

Stereoisomers of Chiral Methyl-Substituted Symmetric and Asymmetric Aryl Piperazinium Compounds Exhibit Distinct Selectivity for α9 and α7 Nicotinic Acetylcholine Receptors

ACS Chemical Neuroscience(2025)10.1021/acschemneuro.5c00204

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0DataRank · unranked

1 citations

Roger L. Papke, Katrin Richter, Veronika Grau, Arik J. Hone, Andrew T. Kerr +4 more

Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of α7 nAChR

Molecular Pharmacology(2020)10.1124/mol.120.119958

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0DataRank · unranked

12 citations

Sumanta Garai, Clare Stokes, Nicole A. Horenstein, Arthur D. Zimmerman, Khalil A. Abboud +2 more

Allosterically Potentiated α7 Nicotinic Acetylcholine Receptors: Reduced Calcium Permeability and Current-Independent Control of Intracellular Calcium

Molecular Pharmacology(2020)10.1124/molpharm.120.000012

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0DataRank · unranked

12 citations

Habibeh Khoshbouei, Sumanta Garai, Lucas Cantwell, Clare Stokes, Ganesh A. Thakur +2 more

Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg

Neuropharmacology(2021)10.1016/j.neuropharm.2021.108553

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0DataRank · unranked

34 citations

Quentin Greba, Anna-Maria Smolyakova, Mariam Alaverdashvili, Wendie N. Marks, Sumanta Garai +9 more

Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms

Neuropharmacology(2021)10.1016/j.neuropharm.2021.108568

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0DataRank · unranked

13 citations

Malia Bautista, Lois S. Akinola, Yasmin Alkhlaif, Asti Jackson, Moriah Carper +7 more