Frank J. Slack

Also affiliated with Harvard University, Harvard Affiliated Emergency Medicine Residency

Biochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 38 papers. Top paper: “A High-Throughput Small Molecule Screen Identifies Ouabain as Synergistic with miR-34a in Killing Lung Cancer Cells”.

A High-Throughput Small Molecule Screen Identifies Ouabain as Synergistic with miR-34a in Killing Lung Cancer Cells

iScience(2020)10.1016/j.isci.2020.100878

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23 citations

Bohyung Yoon, Wen Cai Zhang, Brian D. Adams, Frank J. Slack, Rajesha Rupaimoole

Photodestruction of Stromal Fibroblasts Enhances Tumor Response to PDT in 3D Pancreatic Cancer Coculture Models

Photochemistry and Photobiology(2020)10.1111/php.13339

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21 citations

Imran Rizvi, Frank J. Slack, Jonathan P. Celli, Vida Karimnia

Formulation of PLGA nanoparticles containing short cationic peptide nucleic acids

MethodsX(2020)10.1016/j.mex.2020.101115

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13 citations

Frank J. Slack, Raman Bahal, Shipra Malik

Spatially resolved and multiplexed MicroRNA quantification from tissue using nanoliter well arrays

Microsystems & Nanoengineering(2020)10.1038/s41378-020-0169-8

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36 citations

Augusto M. Tentori, Wen Cai Zhang, Frank J. Slack, Patrick S. Doyle, Maxwell B. Nagarajan

MicroRNA-34a: Potent Tumor Suppressor, Cancer Stem Cell Inhibitor, and Potential Anticancer Therapeutic

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.640587

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185 citations

Yunfei Wang, Ruifang Liu, Andrea L. Kasinski, Haifa Shen, Frank J. Slack +2 more

An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks

Molecular Cancer(2021)10.1186/s12943-021-01401-y

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63 citations

Christos Miliotis, Allison R. Baker, Richard I. Gregory, Frank J. Slack, Pilar Santisteban +1 more

Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency

PLoS ONE(2021)10.1371/journal.pone.0252848

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33 citations

Kaia Mattioli, Chiara Gerhardinger, Philipp G. Maass, Daniel J. Foster, Paola Peinado +5 more

Therapeutic Potential of Chemically Modified, Synthetic, Triplex Peptide Nucleic Acid–Based Oncomir Inhibitors for Cancer Therapy

Cancer Research(2021)10.1158/0008-5472.can-21-0736

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32 citations

Ravinder Reddy Gaddam, Ajit Vikram, Frank J. Slack, Raman Bahal, Karishma Dhuri

Cellular microRNA-127-3p suppresses oncogenic herpesvirus-induced transformation and tumorigenesis via down-regulation of SKP2

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2105428118

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15 citations

Kenneth M. Kaye, Frank J. Slack, Soo Mi Lee

The SWI/SNF complex regulates the expression of miR-222, a tumor suppressor microRNA in lung adenocarcinoma

Human Molecular Genetics(2021)10.1093/hmg/ddab187

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5 citations

Álvaro Andrades, Jordi Martorell‐Marugán, Jeffrey R. Haswell, Frank J. Slack, Pedro Carmona‐Sáez +2 more

Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia

Nature Methods(2021)10.1038/s41592-021-01077-8

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9 citations

Joao A. Paulo, Ryan R. Posey, Vera Mugoni, Nikki R. Kong, Giulia Cheloni +7 more

Severe COVID-19 induces molecular signatures of aging in the human brain

medRxiv(2021)10.1101/2021.11.24.21266779

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22 citations

Jonathan D. Lee, Isaac H. Solomon, Frank J. Slack, Maria Mavrikaki

Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.08.430256

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6 citations

Kaia Mattioli, Chiara Gerhardinger, Philipp G. Maass, Daniel J. Foster, Paola P. Fernandez +4 more

MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state

Cancer Gene Therapy(2022)10.1038/s41417-022-00504-y

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19 citations

Nicholas Skiados, Fareesa Aftab, Cerena Moreno, Luis Silva, Paul Joshua Anthony Corbilla +4 more

Is Evolutionary Conservation a Useful Predictor for Cancer Long Noncoding RNAs? Insights from the Cancer LncRNA Census 3

Non-Coding RNA(2022)10.3390/ncrna8060082

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10 citations

Alejandro H. Gutierrez, Thorben Hennig, Carlos Pulido-Quetglas, Frank J. Slack, Todd A. Johnson +2 more

The Emerging Value of Circular Noncoding RNA Research in Cancer Diagnosis and Treatment

Cancer Research(2023)10.1158/0008-5472.can-22-3014

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49 citations

Erik S. Anderson, Frank J. Slack, Urmila Jagtap

Unlocking the potential of chemically modified peptide nucleic acids for RNA-based therapeutics

RNA(2023)10.1261/rna.079498.122

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34 citations

Shipra Malik, Frank J. Slack, Raman Bahal, Sai Pallavi Pradeep

Next-generation poly-L-histidine formulations for miRNA mimic delivery

Molecular Therapy — Methods & Clinical Development(2023)10.1016/j.omtm.2023.03.015

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15 citations

Aniket Wahane, Chung‐Hao Liu, Lin Yang, Mu‐Ping Nieh, Frank J. Slack +2 more

Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53

Cell Reports(2023)10.1016/j.celrep.2023.113478

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12 citations

Bridget L. Menasché, Maria Mavrikaki, Madison M. Uyemura, Su Min Hong, Nina Kozlova +13 more

MicroRNAs in Age-Related Proteostasis and Stress Responses

Non-Coding RNA(2023)10.3390/ncrna9020026

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14 citations

Frank J. Slack, Latika Matai

Head-to-head comparison of in vitro and in vivo efficacy of pHLIP-conjugated anti-seed gamma peptide nucleic acids

Cell Reports Physical Science(2023)10.1016/j.xcrp.2023.101584

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8 citations

Tibo Duran, Bodhisattwa Chaudhuri, Frank J. Slack, Ajit Vikram, Peter M. Glazer +2 more

PanomiR: a systems biology framework for analysis of multi-pathway targeting by miRNAs

Briefings in Bioinformatics(2023)10.1093/bib/bbad418

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7 citations

Alan Yue Yang Teo, Dimitra Karagkouni, Yered Pita-Juarez, Sarah Morgan, Frank J. Slack +3 more

The conserved microRNA‐229 family controls low‐insulin signaling and dietary restriction induced longevity through interactions with SKN‐1/NRF2

Aging Cell(2023)10.1111/acel.13785

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8 citations

Thalyana Stathis, Jonathan D. Lee, Christine Parsons, Tanvi Saxena, Kovi Shlomchik +2 more

Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.31.555625

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3 citations

Bridget L. Menasché, Maria Mavrikaki, Madison M. Uyemura, Su Min Hong, Nina Kozlova +13 more

Data from microRNA miR-196a-2 and Breast Cancer: A Genetic and Epigenetic Association Study and Functional Analysis

(2023)10.1158/0008-5472.c.6499023

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0 citations

Tongzhang Zheng, Chunhui Yi, Derek Leaderer, Joanne B. Weidhaas, Frank J. Slack +4 more

Data from Therapeutic Potential of Chemically Modified, Synthetic, Triplex Peptide Nucleic Acid–Based Oncomir Inhibitors for Cancer Therapy

(2023)10.1158/0008-5472.c.6513501.v1

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0 citations

Ravinder Reddy Gaddam, Ajit Vikram, Frank J. Slack, Raman Bahal, Karishma Dhuri

Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models

Scientific Reports(2024)10.1038/s41598-024-71372-9

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9 citations

Maryam Labaf, Vida Karimnia, Yiran Liu, Gwendolyn M. Cramer, Joanna B. Dahl +4 more

Sensitive Multiplexed MicroRNA Spatial Profiling and Data Classification Framework Applied to Murine Breast Tumors

Analytical Chemistry(2024)10.1021/acs.analchem.4c01773

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6 citations

Yujing J. Heng, Lin Wang, Abhishek Thavamani, Erica S. Massicott, Gerburg M. Wulf +3 more

Extracellular vesicle‐encapsulated miR‐30c‐5p reduces aging‐related liver fibrosis

Aging Cell(2024)10.1111/acel.14310

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6 citations

Yujing J. Heng, Frank J. Slack, Alice Cristina Rodrigues

Development of bioconjugate-based delivery systems for nucleic acids

RNA(2024)10.1261/rna.080273.124

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4 citations

Vishal Kasina, Mounika Pathuri, Ciara Marro-Wilson, Anisha Gupta, Frank J. Slack +2 more

Cognition-associated long noncoding RNAs are dysregulated upon severe COVID-19

Frontiers in Immunology(2024)10.3389/fimmu.2024.1290523

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4 citations

Isaac H. Solomon, Frank J. Slack, Maria Mavrikaki, Jonathan D. Lee

Enhancing RNA inhibitory activity using clamp-G-modified nucleobases

Cell Reports Physical Science(2024)10.1016/j.xcrp.2024.102120

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3 citations

Vikas Kumar, Shipra Malik, Frank J. Slack, Anisha Gupta, Raman Bahal +1 more

miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.19.613915

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2 citations

Anan Quan, Yuho Ono, Jonathan Lee, Kylie A. Shen, Sergei A. Manakov +4 more

Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.14.602133

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1 citations

Maryam Labaf, Vida Karimnia, Yiran Liu, Gwendolyn M. Cramer, Joanna B. Dahl +4 more

MicroRNA-21 is a potential therapeutic agent targeting Tgfbi and mitigating high-fat-diet-induced liver disease and cancer

Molecular Therapy — Nucleic Acids(2025)10.1016/j.omtn.2025.102752

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2 citations

Anan Quan, Yuho Ono, Jonathan Lee, Alice Cristina Rodrigues, Kylie A. Shen +5 more

Host microRNA-31-5p represses oncogenic herpesvirus lytic reactivation by restricting the RNA-binding protein KHDRBS3-mediated viral gene expression

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.22.634336

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1 citations

Christopher L. Avalos, Christos Miliotis, Hanna M. Doh, Erica Chan, Kenneth M. Kaye +2 more

tRNA modifications are required for stress granule formation and melanoma metastasis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.20.671337

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0 citations

Hannah J Davis, Leona Nease, Paul Zumbo, Mauro Danielli, Wyatt Tran +17 more

Age-dependent transcriptomic effects of morphine in the frontal cortex of female mice

Neuropharmacology(2025)10.1016/j.neuropharm.2025.110809

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0 citations

Anupama Rai, Jonathan D. Lee, Jane Banahan, Kristina Dujic, Masiel Nunez +5 more