Douglas J. Sheffler

Sanford Burnham Prebys Medical Discovery Institute

Also affiliated with Discovery Institute, Center for Cancer Research

Biochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 10 papers. Top paper: “A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors”.

A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.010838

N/A

1.1DataRank · unranked

25 citations

Lester J. Lambert, Douglas J. Sheffler, Laurent J. S. De Backer, Raveendra-Panickar Dhanya, Maria Celeridad +8 more

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors

Journal of Visualized Experiments(2020)10.3791/61457

N/A

0DataRank · unranked

4 citations

Celeste Romero, Douglas J. Sheffler, Maria Celeridad, Nicholas D. P. Cosford, Lutz Tautz +1 more

Ribosomal S6 Kinase 2 Directly Phosphorylates the 5-Hydroxytryptamine 2A (5-HT 2A ) Serotonin Receptor, Thereby Modulating 5-HT 2A Signaling

UNC Libraries(2020)10.17615/4x2x-3j03

N/A

0DataRank · unranked

0 citations

Bryan L. Roth, Michael Kinter, Ryan T. Strachan, Belinda Willard, Douglas J. Sheffler +1 more

Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00804

N/A

0DataRank · unranked

34 citations

A. Chaikuad, Nicole A. Bakas, Allison S. Limpert, Lester J. Lambert, Douglas J. Sheffler +11 more

Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo

Cancer Letters(2022)10.1016/j.canlet.2022.215613

N/A

0DataRank · unranked

18 citations

Yinsong Zhu, Christine Brotherton‐Pleiss, Wen‐Zhen Fu, Nagendra Verma, Jasmine Chen +17 more

Development and use of a high-throughput screen to identify novel modulators of the corticotropin releasing factor binding protein

SLAS DISCOVERY(2022)10.1016/j.slasd.2022.09.005

N/A

0DataRank · unranked

1 citations

T. Chase Francis, Pauravi J. Gandhi, Reesha R. Patel, Mohammad Naemuddin, Carsten K. Nielsen +12 more

Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (DUSP3) Phosphatase

ACS Omega(2025)10.1021/acsomega.4c10321

N/A

0DataRank · unranked

8 citations

Marek R. Baranowski, Alexander E. Aleshin, Eta A. Isiorho, Lester J. Lambert, Laurent J. S. De Backer +9 more

Synthesis and Characterization of ULK1/2 Kinase Inhibitors that Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.05.674519

N/A

0DataRank · unranked

2 citations

Huiyu Ren, Nicole A. Bakas, Dhanya Panickar, Lester J. Lambert, Maria Celeridad +16 more

ULK1/2 Inhibitors that Degrade ATG13 Effectively Target KRAS-Mutant Cancers

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.14.682402

N/A

0DataRank · unranked

0 citations

Huiyu Ren, Sonja N. Brun, Fabiana Izidro Layng, Dhanya Panickar, Lester J. Lambert +10 more

Spontaneous daily sleep disruptions associated with morphine dependence and withdrawal in rats

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103766

N/A

0DataRank · unranked

0 citations

Bethany Pierce, Jesse Lynch, Audrey Kim, Kimberly M. Holter, R.A. Gadient +5 more