Jason M. Brenchley

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 55 papers. Top paper: “SARS-CoV-2 infection perturbs the gastrointestinal tract and induces modest microbial translocation across the intestinal barrier”.

SARS-CoV-2 infection perturbs the gastrointestinal tract and induces modest microbial translocation across the intestinal barrier

Journal of Virology(2024)10.1128/jvi.01288-24

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0.415DataRank · unranked

8 citations

Christine E Nelson, Cynthia C. Aguilar, Timothy N. Hoang, Alexandra M. Ortiz, Charlotte A. Langner +19 more

Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV

JCI Insight(2024)10.1172/jci.insight.174168

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0.222DataRank · unranked

3 citations

Carly E. Starke, Alexandra M. Ortiz, Amy Ransier, Samuel Darko, Sian Llewellyn‐Lacey +6 more

SIV infection and ARV treatment reshape the transcriptional and epigenetic profile of naïve and memory T cells in vivo

Journal of Virology(2024)10.1128/jvi.00283-24

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0.174DataRank · unranked

2 citations

Tovah E. Markowitz, Joseph C. Mudd, Alexandra M. Ortiz, Jason M. Brenchley, Andrew R. Rahmberg

Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of MultiplePneumocystisSpecies

mBio(2020)10.1128/mbio.02878-19

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20 citations

Zehua Chen, Da Wei Huang, Ousmane H. Cissé, Jamie L. Rothenburger, Alice Latinne +28 more

Simian Immunodeficiency Virus-Infected Memory CD4+T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS

mBio(2020)10.1128/mbio.00602-20

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16 citations

Erin Beasley, Karthikeyan Sundar, Margery Smelkinson, Carol L. Vinton, Claire Deléage +7 more

Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys

JCI Insight(2020)10.1172/jci.insight.139043

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11 citations

Stephen Y. Lai, Sanjana Shah, Andrew R. Rahmberg, Jacob K. Flynn, Carly E. Starke +8 more

Nonhuman primates exposed to Zika virus in utero are not protected against reinfection at 1 year postpartum

Science Translational Medicine(2020)10.1126/scitranslmed.aaz4997

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6 citations

Sydney Stein, Mark Connelly, Joanna Swerczek, Emérito Amaro-Carambot, Elizabeth M. Coyle +17 more

A study of microbial translocation markers in mastocytosis

Clinical & Experimental Allergy(2020)10.1111/cea.13798

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6 citations

Jason M. Brenchley, A. Robin Eisch, Michael L. Young, Linda M. Scott, Joseph M. Kulinski +4 more

TCF-1 regulates the stem-like memory potential of HIV-specific CD8+ T cells in elite controllers

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.07.894535

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3 citations

Christian Deo T. Deguit, Joseph Hiatt, Franziska Blaeschke, Theodore L. Roth, Lynn Wang +21 more

Translocated microbiome composition determines immunological outcome in treated HIV infection

Cell(2021)10.1016/j.cell.2021.05.023

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0DataRank · unranked

80 citations

Aarthi Talla, Ashish Sharma, Samuel Darko, Amy Ransier, Farida Laboune +30 more

Genomic insights into the host specific adaptation of the Pneumocystis genus

Communications Biology(2021)10.1038/s42003-021-01799-7

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40 citations

Liang Ma, John P. Dekker, Pavel P. Khil, Jung-Ho Youn, Jason M. Brenchley +20 more

Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART

PLoS Pathogens(2021)10.1371/journal.ppat.1009825

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29 citations

Susan Pereira Ribeiro, Amélie Pagliuzza, Khader Ghneim, Anum N. Khan, Emily S. Ryan +16 more

The Vaginal Microbiome of Nonhuman Primates Can Be Only Transiently Altered to Become Lactobacillus Dominant without Reducing Inflammation

Microbiology Spectrum(2021)10.1128/spectrum.01074-21

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21 citations

Alexandra M. Ortiz, Jacob K. Flynn, Heather Kendall, Laurel A. Lagenaur, Jason M. Brenchley +1 more

A Randomized, Placebo-Controlled Trial Assessing the Effect of VISBIOME ES Probiotic in People With HIV on Antiretroviral Therapy

Open Forum Infectious Diseases(2021)10.1093/ofid/ofab550

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19 citations

Eunice Yeh, Brett Williams, Alan Landay, Jeffrey M. Jacobson, Cara C. Wilson +12 more

Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

PLoS Pathogens(2021)10.1371/journal.ppat.1009565

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15 citations

Kathleen Busman‐Sahay, Stephen Bondoc, David Morrow, Alexandra M. Ortiz, Christine M. Fennessey +18 more

Microbiome Studies in Non-human Primates

Current HIV/AIDS Reports(2021)10.1007/s11904-021-00584-9

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14 citations

Alexandra M. Ortiz, Jason M. Brenchley

FRugally Optimized DNA Octomer (FRODO) qPCR Measurement of HIV and SIV in Human and Nonhuman Primate Samples

Current Protocols(2021)10.1002/cpz1.93

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4 citations

Jason M. Brenchley, Charlotte A. Langner

Luminal microvesicles uniquely influence translocating bacteria after SIV infection

Mucosal Immunology(2021)10.1038/s41385-021-00393-8

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3 citations

Charlotte A. Langner, Erik P. Karmele, Phillip J. Baker, Luxin Pei, Edlawit G. Gorfu +10 more

Systemic IgG repertoire as a biomarker for translocating gut microbiota members

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.17.456549

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2 citations

Hugh C. Welles, Connie Ha, Lutfi Huq, Shreni Mistry, Jason M. Brenchley +4 more

CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.17.473203

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2 citations

Christine E Nelson, Keith D. Kauffman, Nickiana E. Lora, Caian L. Vinhaes, Danielle E. Dorosky +15 more

The systemic anti-microbiota IgG repertoire can identify gut bacteria that translocate across gut barrier surfaces

Science Translational Medicine(2022)10.1126/scitranslmed.abl3927

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0DataRank · unranked

78 citations

Hugh C. Welles, Connie Ha, Lutfi Huq, Shreni Mistry, Jason M. Brenchley +4 more

CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection

Cell Reports(2022)10.1016/j.celrep.2022.110896

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0DataRank · unranked

38 citations

Christine E Nelson, Keith D. Kauffman, Nickiana E. Lora, Caian L. Vinhaes, Danielle E. Dorosky +14 more

Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues

Science Immunology(2022)10.1126/sciimmunol.abo0535

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37 citations

Sivaranjani Namasivayam, Taylor W. Foreman, Keith D. Kauffman, Shunsuke Sakai, Danielle E. Dorosky +29 more

Host Genetics and Environment Shape the Composition of the Gastrointestinal Microbiome in Nonhuman Primates

Microbiology Spectrum(2022)10.1128/spectrum.02139-22

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13 citations

Alexandra M. Ortiz, Richard Herbert, Jason M. Brenchley, Jacob K. Flynn

The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence

PLoS Pathogens(2022)10.1371/journal.ppat.1010723

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9 citations

Timothy N. Hoang, Gregory K. Tharp, Andrew R. Rahmberg, Justin Harper, Kevin Nguyen +12 more

Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques

Scientific Reports(2022)10.1038/s41598-022-11122-x

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17 citations

Jennifer Simpson, Charlotte A. Langner, Phillip J. Baker, Cynthia C. Aguilar, Kelsie Brooks +6 more

mTOR regulation of metabolism limits LPS-induced monocyte inflammatory and procoagulant responses

Communications Biology(2022)10.1038/s42003-022-03804-z

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13 citations

Yetunde I. Kayode, Melanie R. McReynolds, Deanna C. Clemmer, Hannah Hudson, Isabelle Clerc +6 more

Epigenetic Reprogramming Leads to Downregulation of CD4 and Functional Changes in African Green Monkey Memory CD4+ T Cells

The Journal of Immunology(2022)10.4049/jimmunol.2200109

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6 citations

Tovah E. Markowitz, Joseph C. Mudd, Vanessa M. Hirsch, Jason M. Brenchley, Andrew R. Rahmberg

Multiple modes of antigen exposure induce clonotypically diverse epitope-specific CD8+ T cells across multiple tissues in nonhuman primates

PLoS Pathogens(2022)10.1371/journal.ppat.1010611

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6 citations

Carly E. Starke, Alexandra M. Ortiz, Amy Ransier, Samuel Darko, Daniel C. Douek +2 more

Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.06.475282

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14 citations

Sivaranjani Namasivayam, Taylor W. Foreman, Keith D. Kauffman, Shunsuke Sakai, Danielle E. Dorosky +14 more

IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.13.507852

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9 citations

Taylor W. Foreman, Keith D. Kauffman, Shunsuke Sakai, Sydnee T. Gould, Joel D. Fleegle +18 more

Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys

Nature Communications(2023)10.1038/s41467-023-36379-2

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13 citations

Paola Sette, Cuiling Xu, Andrew R. Rahmberg, Lilas Tarnus, Haritha Annapureddy +12 more

Ongoing production of tissue-resident macrophages from hematopoietic stem cells in healthy adult macaques

Blood Advances(2023)10.1182/bloodadvances.2023011499

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13 citations

Chuanfeng Wu, Tae–Hoon Shin, So Gun Hong, Luxin Pei, Tovah E. Markowitz +4 more

sCD14 and Intestinal Fatty Acid Binding Protein Are Elevated in the Serum of Patients With Idiopathic Anaphylaxis

The Journal of Allergy and Clinical Immunology In Practice(2023)10.1016/j.jaip.2023.03.037

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10 citations

Melody C. Carter, Jason M. Brenchley, Hyejeong Bolan, Linda M. Scott, Yun Bai +3 more

Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility

Cell Reports(2023)10.1016/j.celrep.2023.112020

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9 citations

Phillip J. Baker, Charlotte A. Langner, Jennifer Simpson, Apollo Stacy, Jacob K. Flynn +7 more

Selective IgA2 deficiency in a patient with small intestinal Crohn’s disease

Journal of Clinical Investigation(2023)10.1172/jci167742

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6 citations

Yolanda García-Carmona, Joan Shang, Hadar Meringer, Debra Yee, Lin Radigan +15 more

2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques

Journal of Virology(2023)10.1128/jvi.00600-23

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1 citations

Fabiola Castello Casta, Andrew R. Rahmberg, Tovah E. Markowitz, Kelsie Brooks, Jennifer Simpson +2 more

Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

PLoS Pathogens(2023)10.1371/journal.ppat.1011343

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0DataRank · unranked

0 citations

Kathleen Busman‐Sahay, Stephen Bondoc, David Morrow, Alexandra M. Ortiz, Christine M. Fennessey +18 more

The Host Adapted Fungal Pathogens of Pneumocystis Genus Utilize Genic Regional Centromeres

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.12.540427

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0DataRank · unranked

0 citations

Shelly Curran, H. Diego Folco, Yueqin Liu, Lisa Bishop, Honghui Wang +14 more

Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells

UNC Libraries(2023)10.17615/8kqt-ff05

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0 citations

Jason M. Brenchley, Jacqueline D. Reeves, Kelly Stefano Cole, Carlos Cano, Jessica C. Engram +11 more

Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence

Nature Immunology(2024)10.1038/s41590-024-01875-0

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31 citations

Laurence Raymond Marchand, Claire Deléage, M. Betina Pampena, Maria A. Cardenas, Christian M. Beusch +25 more

From dysbiosis to defense: harnessing the gut microbiome in HIV/SIV therapy

Microbiome(2024)10.1186/s40168-024-01825-w

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22 citations

Sergio Serrano‐Villar, Jason M. Brenchley

IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

PLoS Pathogens(2024)10.1371/journal.ppat.1012339

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0DataRank · unranked

22 citations

Taylor W. Foreman, Eduardo R. Fukutani, Keith D. Kauffman, Shunsuke Sakai, Joel D. Fleegle +22 more

Recombinant OC43 SARS-CoV-2 spike replacement virus: An improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2310421121

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12 citations

Alberto Domingo López-Muñoz, Ivan Košík, Tiansheng Li, Victoria Callahan, Kelsie Brooks +11 more

Untangling the role of the microbiome across the stages of HIV disease

Current Opinion in HIV and AIDS(2024)10.1097/coh.0000000000000870

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5 citations

Jason M. Brenchley, Alexandra M. Ortiz

Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases

Mucosal Immunology(2024)10.1016/j.mucimm.2024.07.008

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2 citations

Alexandra M. Ortiz, Ivan Vujkovic-Cvijin, Hugh C. Welles, Jennifer Simpson, Fabiola M. Castello Casta +12 more

Activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.23.604823

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1 citations

Nathânia Dábilla, Colton McNinch, Jason M. Brenchley, Patrick Dolan, Julie Fox +1 more

Multi-omics analysis of SIV-specific CD8+ T cells in multiple anatomical sites

PLoS Pathogens(2024)10.1371/journal.ppat.1012545

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0 citations

Brittany Dulek, Paul Schaughency, Jason M. Brenchley, Jennifer Simpson

Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primates

Nature Communications(2025)10.1038/s41467-025-59826-8

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14 citations

Catherine A. Cotter, Maxinne A. Ignacio, Patricia L. Earl, Rory A. Hills, Mark Howarth +4 more

A de novo dominant-negative PSMB8 mutation causes severe CANDLE/PRAAS due to arrested proteasome biogenesis

Annals of the Rheumatic Diseases(2025)10.1016/j.ard.2025.10.021

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5 citations

Sara Alehashemi, Martin Wendlandt, Franziska G. Thiel, Adriana A. de Jesus, Jonas Johannes Papendorf +46 more

Interaction of the endogenous antibody response with activating FcγRs enhance control of Mayaro virus through monocytes

PLoS Pathogens(2025)10.1371/journal.ppat.1012944

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1 citations

Nathânia Dábilla, Colton McNinch, Jason M. Brenchley, Patrick Dolan, Julie M. Fox +1 more

HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases

Nature Communications(2020)10.1038/s41467-020-16222-8

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231 citations

Ornella Sortino, Eveline Verheij, Jack Sklar, Ferdinand W.N.M. Wit, Neeltje A. Kootstra +8 more

Repeated enema administration in rhesus macaques is not sufficient to promote bacterial dysbiosis or gastrointestinal dysfunction

Mucosal Immunology(2025)10.1016/j.mucimm.2025.06.002

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0 citations

Fabiola Castello Casta, Elizabeth G Bodykevich, Jacob K. Flynn, Christine M. Fennessey, Kelsie Brooks +7 more

HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells

Nature Immunology(2020)10.1038/s41590-020-0593-9

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96 citations

Lawrence M. Lifshitz, Kyle Gellatly, Carol L. Vinton, Kathleen Busman‐Sahay, Sean Matthew McCauley +16 more

TCF-1 regulates HIV-specific CD8+ T cell expansion capacity

JCI Insight(2020)10.1172/jci.insight.136648

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0DataRank · unranked

89 citations

Christian Deo T. Deguit, Joseph Hiatt, Franziska Blaeschke, Theodore L. Roth, Lynn Wang +21 more