Ken S. Lau

Immunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.1Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

Cell(2020)10.1016/j.cell.2020.03.053

Top 4%

5.6DataRank

Top 4%609 citations

Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer E. Rood +92 more

Papers

Driven by 66 papers — median percentile 83. Top paper: “Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer”.

Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer

Cell(2023)10.1016/j.cell.2022.12.028

N/A

7.0DataRank · unranked

290 citations

Shu Wang, Shannon Coy, Yu‐An Chen, Clarence Yapp, Madison Tyler +6 more

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

Cell(2020)10.1016/j.cell.2020.03.053

Top 4%

5.6DataRank

Top 4%609 citations

Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer E. Rood +92 more

A Roadmap for the Human Gut Cell Atlas

Nature Reviews Gastroenterology & Hepatology(2023)10.1038/s41575-023-00784-1

Top 17%

1.2DataRank

Top 17%51 citations

Kylie R. James, Mandeep Kaur, Sebastian Pott, Zhixin Li, Albert Burger +37 more

Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn’s disease

Nature Communications(2024)10.1038/s41467-024-51580-7

N/A

1.1DataRank · unranked

49 citations

Alan J. Simmons, Caroline V. Hawkins, Sophie Chiron, Marisol Ramirez‐Solano, Naila Tasneem +34 more

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

Cell(2021)10.1016/j.cell.2021.11.031

N/A

0.871DataRank · unranked

332 citations

Cherie’ R. Scurrah, Eliot T. McKinley, Alan J. Simmons, Marisol A. Ramirez-Solano, Xiangzhu Zhu +48 more

Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1273

N/A

0.741DataRank · unranked

139 citations

Jie Chen, Nicholas O. Markham, Reece J. Knippel, Jada C. Domingue, Ada Tam +26 more

A Quantitative Framework for Evaluating Single-Cell Data Structure Preservation by Dimensionality Reduction Techniques

Cell Reports(2020)10.1016/j.celrep.2020.107576

N/A

0.650DataRank · unranked

75 citations

Ken S. Lau, Cody N. Heiser

Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer

Cell Systems(2022)10.1016/j.cels.2022.07.006

N/A

0.614DataRank · unranked

59 citations

Geena V. Ildefonso, Caitlin O. McAtee, Patricia Midori Murobushi Ozawa, Abbie S. Ireland, Philip E. Stauffer +21 more

MIRIAM: A machine and deep learning single‐cell segmentation and quantification pipeline for multi‐dimensional tissue images

Cytometry Part A(2022)10.1002/cyto.a.24541

N/A

0.524DataRank · unranked

32 citations

Justin Shao, Samuel T. Ellis, Cody N. Heiser, Joseph T. Roland, Mary C. Macedonia +5 more

Multiplexed 3D atlas of state transitions and immune interactions in colorectal cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.31.437984

N/A

0.510DataRank · unranked

29 citations

Shu Wang, Shannon Coy, Yu‐An Chen, Clarence Yapp, Madison Tyler +6 more

Oncogenic K-Ras suppresses global miRNA function

Molecular Cell(2023)10.1016/j.molcel.2023.06.008

N/A

0.442DataRank · unranked

18 citations

Tyler S. Beyett, Zhengyi Chen, Xiaoyi Li, Gaspare La Rocca, William Gazlay +5 more

Dipeptidase-1–knockout mice develop invasive tumors with features of microsatellite-unstable colorectal cancer

JCI Insight(2025)10.1172/jci.insight.186938

N/A

0.326DataRank · unranked

4 citations

Matthew E. Bechard, Zheng Cao, Radhika Aramandla, Ping Zhao, Samuel T. Ellis +19 more

Pancreatic islet β-cell subtypes are derived from biochemically-distinct and nutritionally-regulated islet progenitors

Nature Communications(2025)10.1038/s41467-025-60831-0

N/A

0.312DataRank · unranked

7 citations

Verda E. Miranda, Simone Nevills, Ruiying Hu, Prasanna K. Dadi, Alan J. Simmons +11 more

Single-Cell Mass Cytometry of Archived Human Epithelial Tissue for Decoding Cancer Signaling Pathways

Methods in Molecular Biology(2019)10.1007/978-1-4939-8885-3_15

N/A

0.312DataRank · unranked

7 citations

Alan J. Simmons, Ken S. Lau, Cherie’ R. Scurrah

Effects of KRAS Genetic Interactions on Outcomes in Cancers of the Lung, Pancreas, and Colorectum

Cancer Epidemiology Biomarkers & Prevention(2023)10.1158/1055-9965.epi-23-0262

N/A

0.299DataRank · unranked

6 citations

John V. Heymach, Kenneth L. Kehl, Scott Kopetz, Ken S. Lau, Gregory J. Riely +5 more

Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells

The Journal of Cell Biology(2024)10.1083/jcb.202404070

N/A

0.292DataRank · unranked

6 citations

Evan Krystofiak, Leah Caplan, Ken S. Lau, Matthew J. Tyska, Jennifer B. Silverman

Human colorectal pre-cancer atlas identifies distinct molecular programs underlying two major subclasses of pre-malignant tumors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.11.426044

Top 59%

0.262DataRank

Top 59%3 citations

Eliot T. McKinley, Alan J. Simmons, Marisol Ramirez‐Solano, Xiangzhu Zhu, Austin N. Southard-Smith +23 more

Predicting Crohn’s disease severity in the colon using mixed cell nucleus density from pseudo labels

PubMed(2023)10.1117/12.2653918

N/A

0.241DataRank · unranked

4 citations

Shunxing Bao, Cailey I. Kerley, Leon Y. Cai, François Rheault, Ruining Deng +10 more

Consensus tissue domain detection in spatial omics data using multiplex image labeling with regional morphology (MILWRM)

Communications Biology(2024)10.1038/s42003-024-06281-8

N/A

0.165DataRank · unranked

2 citations

Cody N. Heiser, Eliot T. McKinley, Lissa Ventura‐Antunes, Coleman R. Harris, Joseph T. Roland +11 more

Cell spatial analysis in Crohn's disease: unveiling local cell arrangement pattern with graph-based signatures

PubMed(2024)10.1117/12.3006675

N/A

0.165DataRank · unranked

2 citations

Si-Chen Zhu, Vasantha L. Kolachala, Lucas W. Remedios, Yeonjoo Hwang, Yutong Sun +15 more

Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention

The American Journal of Human Genetics(2025)10.1016/j.ajhg.2025.11.008

N/A

0.165DataRank · unranked

2 citations

Qingyuan Song, Zhishan Chen, Jung-Yoon Choi, Victor Moreno, Jie Ping +26 more

Coordinated changes in stromal and hematopoietic cells that define the perinatal to juvenile transition in the mouse thymus

Cell Reports(2025)10.1016/j.celrep.2025.116677

N/A

0.165DataRank · unranked

2 citations

Colin E. Moore, Aparna Calindi, Seungwoo Kang, Bryan R. Helm, Jayashree Srinivasan +13 more

Mutant GNAS drives a pyloric metaplasia with tumor suppressive glycans in intraductal papillary mucinous neoplasia

Cell Reports(2025)10.1016/j.celrep.2025.116684

N/A

0.104DataRank · unranked

1 citations

Katherine E. Ankenbauer, Sabrina M. Torbit, C. Taranto, Jiayue Liu, Maëlle Batardière +21 more

MTGR1 is required to maintain small intestinal stem cell populations

Research Square(2023)10.21203/rs.3.rs-3315071/v1

N/A

0.104DataRank · unranked

1 citations

Rachel E. Brown, Koral M. Blunt, Jennifer M. Pilat, Lucy Chen, Justin Jacobse +11 more

Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury

Gastroenterology(2021)10.1053/j.gastro.2021.10.027

N/A

0DataRank · unranked

115 citations

Nikki K. Lytle, Bob Chen, Nidhi Jyotsana, Sammy Weiser Novak, Charles J. Cho +19 more

Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells

Cell Reports(2023)10.1016/j.celrep.2023.112128

N/A

0DataRank · unranked

48 citations

Rachel E. Brown, Jing Li, Jennifer M. Pilat, Ly Pham, Sarah P. Short +20 more

A contamination focused approach for optimizing the single-cell RNA-seq experiment

iScience(2023)10.1016/j.isci.2023.107242

N/A

0DataRank · unranked

24 citations

Zhengyi Chen, Alan J. Simmons, Cody N. Heiser, Austin N. Southard-Smith, Michael J. Brenan +8 more

Combinatorial transcriptional profiling of mouse and human enteric neurons identifies shared and disparate subtypes in situ

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.03.187211

N/A

0DataRank · unranked

0 citations

Eric Tycksen, Austin N. Southard-Smith, Karen K. Deal, Joseph T. Benthal, Dennis P. Buehler +9 more

SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions

Journal of Clinical Investigation(2023)10.1172/jci165988

N/A

0DataRank · unranked

30 citations

Rachel E. Brown, Zhengyi Chen, Nathaniel J. Berle, Adrian P. Othon, M. Kay Washington +12 more

A Specialized Epithelial Cell Type Regulating Mucosal Immunity and Driving Human Crohn’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.30.560293

N/A

0DataRank · unranked

10 citations

Alan J. Simmons, Sophie Chiron, Marisol Ramirez‐Solano, Naila Tasneem, Harsimran Kaur +24 more

Topological-preserving membrane skeleton segmentation in multiplex immunofluorescence imaging

PubMed(2023)10.1117/12.2654087

N/A

0DataRank · unranked

0 citations

Can Cui, Jia Li, Yucheng Tang, Ho Hin Lee, Ruining Deng +13 more

Cell Spatial Analysis in Crohn's Disease: Unveiling Local Cell Arrangement Pattern with Graph-based Signatures

arXiv (Cornell University)(2023)10.48550/arxiv.2308.10166

N/A

0DataRank · unranked

0 citations

Si-Chen Zhu, Vasantha L. Kolachala, Lucas W. Remedios, Yeonjoo Hwang, Yutong Sun +14 more

Cross-scale multi-instance learning for pathological image diagnosis

Medical Image Analysis(2024)10.1016/j.media.2024.103124

N/A

0DataRank · unranked

84 citations

Can Cui, Lucas W. Remedios, Shunxing Bao, R. Michael Womick, Sophie Chiron +10 more

Automated quality control and cell identification of droplet-based single-cell data using dropkick

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.08.332288

N/A

0DataRank · unranked

5 citations

Victoria M. Wang, Bob Chen, Jacob J. Hughey, Ken S. Lau, Cody N. Heiser

Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids

Cell Reports(2024)10.1016/j.celrep.2024.114874

N/A

0DataRank · unranked

33 citations

Mia R Haschert, José C. Zepeda, Aaron B. Simmons, A K Yates, Daniel Chavarría +15 more

MTGR1 is required to maintain small intestinal stem cell populations

Cell Death and Differentiation(2024)10.1038/s41418-024-01346-x

N/A

0DataRank · unranked

4 citations

Rachel E. Brown, Zhengyi Chen, Jennifer M. Pilat, Bailey A McElligott, Leslie M. Meenderink +14 more

Mutant GNAS drives a pyloric metaplasia with tumor suppressive glycans in intraductal papillary mucinous neoplasia

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.25.581948

N/A

0DataRank · unranked

3 citations

Katherine E. Ankenbauer, Sabrina M. Torbit, Jiayue Liu, Maëlle Batardière, Bhoj Kumar +20 more

Nucleus subtype classification using inter-modality learning

PubMed(2024)10.1117/12.3006237

N/A

0DataRank · unranked

2 citations

Shunxing Bao, Samuel W. Remedios, Ho Hin Lee, Leon Y. Cai, Thomas Li +12 more

Data-driven Nucleus Subclassification on Colon H&E using Style-transferred Digital Pathology

arXiv (Cornell University)(2024)10.48550/arxiv.2407.06116

N/A

0DataRank · unranked

1 citations

Shunxing Bao, Samuel W. Remedios, Ho Hin Lee, Leon Y. Cai, Thomas Li +14 more

Nucleus subtype classification using inter-modality learning

arXiv (Cornell University)(2024)10.48550/arxiv.2401.05602

N/A

0DataRank · unranked

0 citations

Shunxing Bao, Samuel W. Remedios, Ho Hin Lee, Leon Y. Cai, Thomas Li +12 more

Endocrine islet β-cell subtypes with differential function are derived from biochemically distinct embryonic endocrine islet progenitors that are regulated by maternal nutrients

Research Square(2024)10.21203/rs.3.rs-3946483/v1

N/A

0DataRank · unranked

0 citations

Monica Brown, Verda Agan, Simone Nevills, Ruiying Hu, Alan J. Simmons +11 more

Mitigating Over-Saturated Fluorescence Images Through a Semi-Supervised Generative Adversarial Network

PubMed(2024)10.1109/isbi56570.2024.10635687

N/A

0DataRank · unranked

0 citations

Junlin Guo, Ho Hin Lee, Ruining Deng, Can Cui, Lucas W. Remedios +14 more

Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification

Cell Reports(2025)10.1016/j.celrep.2025.115680

N/A

0DataRank · unranked

12 citations

Timothy J. Scott, Jacqueline A. Yap, Annelie Johansson, Fabio Puddu, Tom Charlesworth +6 more

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

Science Signaling(2020)10.1126/scisignal.aay3258

N/A

0DataRank · unranked

47 citations

Manu P. Kumar, Evan L. Chiswick, Cecil Gregg, Alina Starchenko, Paige N. Vega +8 more

Interleukin-10 production by innate lymphoid cells restricts intestinal inflammation in mice

Mucosal Immunology(2025)10.1016/j.mucimm.2025.02.005

N/A

0DataRank · unranked

7 citations

Justin Jacobse, Jennifer M. Pilat, Harsimran Kaur, Weihong Gu, Seungwoo Kang +18 more

Insulin-like growth factor 2 as a driving force for exponential expansion and differentiation of the neonatal thymus

Development(2025)10.1242/dev.204347

N/A

0DataRank · unranked

3 citations

Bryan R. Helm, Zhifeng Yu, Shiyun Xiao, Wen Zhang, Anusha Vasudev +6 more

3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer

Communications Biology(2025)10.1038/s42003-025-08699-0

N/A

0DataRank · unranked

3 citations

Thomas P. Hasaka, Chelsie K. Sievers, Seung Woo Kang, Marisol Ramirez, Vivian Truong Jones +9 more

Integration of elemental imaging and spatial transcriptomic profiling for proof-of-concept metals-based pathway analysis of colon tumor microenvironment

Metallomics(2025)10.1093/mtomcs/mfaf034

N/A

0DataRank · unranked

1 citations

Neha Shaik, Yunrui Lu, Matthew Chan, Alos Diallo, John P. Zavras +15 more

Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling

Mucosal Immunology(2025)10.1016/j.mucimm.2025.07.005

N/A

0DataRank · unranked

1 citations

Harsimran Kaur, Jia Luo, Mai-Uyen Nguyen, Alyssa Laguerta, Andrew Fong +7 more

Histology-Based Virtual RNA Inference Identifies Pathways Associated with Metastasis Risk in Colorectal Cancer

medRxiv(2025)10.1101/2025.04.22.25326170

N/A

0DataRank · unranked

1 citations

Minh‐Khang Le, Zarif Azher, Xiaoying Liu, Louis Vaickus, Harsimran Kaur +7 more

Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.04.630951

N/A

0DataRank · unranked

0 citations

Jiawei Wang, Erin P. Smith, Luisella Spiga, Alan J. Simmons, Tae Woo Kim +27 more

The Great Reset: A “Tuft” Journey Towards Tumorigenesis

Cellular and Molecular Gastroenterology and Hepatology(2025)10.1016/j.jcmgh.2025.101476

N/A

0DataRank · unranked

0 citations

Ken S. Lau, Monica E Brown

Identifying cellular neighborhood phenotypes differentiating normal and quiescent Crohn’s disease via MxIF

PubMed(2025)10.1117/12.3047121

N/A

0DataRank · unranked

0 citations

Shunxing Bao, Aravind R. Krishnan, Lucas W. Remedios, Michael E. Kim, Adam M. Saunders +9 more

Histology-Based Virtual RNA Inference Identifies Pathways Associated With Metastasis Risk in Colorectal Cancer

Modern Pathology(2025)10.1016/j.modpat.2025.100866

N/A

0DataRank · unranked

0 citations

Minh‐Khang Le, Zarif Azher, Xiaoying Liu, Louis Vaickus, Harsimran Kaur +7 more

Multi-ancestry genome-wide and transcriptome-wide association analyses identified new risk loci and genes for inflammatory bowel disease

medRxiv(2025)10.1101/2025.09.23.25336483

N/A

0DataRank · unranked

0 citations

Qing Li, Chao Li, Ghadeer K. Dawwas, You Chen, Ran Tao +10 more

Combinatorial Transcriptional Profiling of Mouse and Human Enteric Neurons Identifies Shared and Disparate Subtypes In Situ

Gastroenterology(2020)10.1053/j.gastro.2020.09.032

N/A

0DataRank · unranked

126 citations

Eric Tycksen, Austin N. Southard-Smith, Karen K. Deal, Joseph T. Benthal, Dennis P. Buehler +9 more

Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.16.452359

N/A

0DataRank · unranked

6 citations

Eliot T. McKinley, Joseph T. Roland, Qipei LIU, Martha J. Shrubsole, Ken S. Lau +4 more

MTG16 (CBFA2T3) regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.03.467178

N/A

0DataRank · unranked

2 citations

Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega +15 more

Automated quality control and cell identification of droplet-based single-cell data using dropkick

Genome Research(2021)10.1101/gr.271908.120

N/A

0DataRank · unranked

53 citations

Victoria M. Wang, Bob Chen, Jacob J. Hughey, Ken S. Lau, Cody N. Heiser

Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment

Acta Biomaterialia(2022)10.1016/j.actbio.2022.04.031

N/A

0DataRank · unranked

73 citations

Wenjun Wang, Alan J. Simmons, Austin N. Southard-Smith, Bob Chen, Joshua D. Greenlee +6 more

Deciphering the cancer microenvironment from bulk data with EcoTyper

Cell(2021)10.1016/j.cell.2021.09.028

N/A

0DataRank · unranked

12 citations

Bob Chen, Ken S. Lau, Andrea Rolong

Dysplastic Stem Cell Plasticity Functions as a Driving Force for Neoplastic Transformation of Precancerous Gastric Mucosa

Gastroenterology(2022)10.1053/j.gastro.2022.06.021

N/A

0DataRank · unranked

50 citations

Changqing Zhang, R. Jarrett Bliton, Brianna M. Caldwell, Leah Caplan, Kimberly S. Presentation +12 more

Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images

Bioinformatics(2021)10.1093/bioinformatics/btab877

N/A

0DataRank · unranked

38 citations

Eliot T. McKinley, Joseph T. Roland, Qi Liu, Martha J. Shrubsole, Ken S. Lau +4 more

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors

JCI Insight(2022)10.1172/jci.insight.153045

N/A

0DataRank · unranked

16 citations

Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega +15 more

A contamination focused approach for optimizing the single-cell RNA-seq experiment

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.25.513758

N/A

0DataRank · unranked

1 citations

Zhengyi Chen, Alan J. Simmons, Cody N. Heiser, Austin N. Southard-Smith, Michael J. Brenan +8 more

Metaplasia‐induced Epithelial Heterogeneity Directs Pancreatic Injury and Tumorigenesis

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.0i661

N/A

0DataRank · unranked

0 citations

Zhibo Ma, Nikki K. Lytle, Bob Chen, Nidhi Jyotsana, Sammy Weiser Novak +13 more

Ken S. Lau

Indexed papers

Top data-sharing exemplar

Papers