Sarah L. Gaffen

ORCID: 0000-0001-8511-2041

Also affiliated with University of Pittsburgh Medical Center

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 29 papers. Top paper: “Oral epithelial IL-22/STAT3 signaling licenses IL-17–mediated immunity to oral mucosal candidiasis”.

Oral epithelial IL-22/STAT3 signaling licenses IL-17–mediated immunity to oral mucosal candidiasis

Science Immunology(2020)10.1126/sciimmunol.aba0570

N/A

0.717DataRank · unranked

118 citations

Timothy J. Break, Giraldina Trevejo-Nuñez, Natasha Whibley, Bianca M. Coleman, Rachel D. Bailey +12 more

The m 6 A reader IMP2 directs autoimmune inflammation through an IL-17– and TNFα-dependent C/EBP transcription factor axis

Science Immunology(2021)10.1126/sciimmunol.abd1287

N/A

0.673DataRank · unranked

88 citations

Nilesh Amatya, Rachel D. Bailey, Yang Li, Felix E.Y. Aggor, Dedong Li +11 more

Focus on fungi

Cell(2024)10.1016/j.cell.2024.08.016

N/A

0.626DataRank · unranked

64 citations

Gordon D. Brown, Petra Bächer, Sarah L. Gaffen, Joseph Heitman, Bruce S. Klein +2 more

The RNA binding protein Arid5a drives IL-17–dependent autoantibody-induced glomerulonephritis

The Journal of Experimental Medicine(2024)10.1084/jem.20240656

N/A

0.530DataRank · unranked

11 citations

Shachi Vyas, Isha Mehta, Nariaki Asada, Ipsita Dey, Tiffany C. Taylor +16 more

Infections in the monogenic autoimmune syndrome APECED

Current Opinion in Immunology(2021)10.1016/j.coi.2021.07.011

N/A

0.510DataRank · unranked

29 citations

Timothy J. Break, Sarah L. Gaffen, Niki M. Moutsopoulos, Michail S. Lionakis, Vasileios Oikonomou

SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor

The Journal of Immunology(2023)10.4049/jimmunol.2300110

N/A

0.406DataRank · unranked

14 citations

Karsen E. Shoger, Mst Shamima Khatun, Mrinal K. Sarkar, Ipsita Dey, Tiffany C. Taylor +7 more

Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint

Science Signaling(2023)10.1126/scisignal.abo6555

N/A

0.269DataRank · unranked

5 citations

Wenjuan Yang, Dhivyaa Rajasundaram, Alexander Brady, Saikat Majumder, Sarah L. Gaffen +4 more

Extracellular ATP released from Candida albicans activates non-peptidergic neurons to augment host defense

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.27.921049

N/A

0.165DataRank · unranked

2 citations

Shiqun Zhang, Andrew Liu, Jonathan Cohen, Paul Yifan Zhou, Selene Mogavero +11 more

Antibody-induced glomerulonephritis is amplified by RTEC-intrinsic IL-17 signaling and restrained by IL-17-mediated induction of the endoribonuclease Regnase-1 ( Zc3h12a )

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.11.425972

N/A

0DataRank · unranked

2 citations

Rami Bechara, Kritika Ramani, Chetan V. Jawale, Yang Li, Jay K. Kolls +3 more

Regnase-1 deficiency restrains Klebsiella pneumoniae infection by regulation of a Type I interferon response

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.20.469389

N/A

0DataRank · unranked

2 citations

Becky Lin, Li Fan, Felix E.Y. Aggor, Partha S. Biswas, Kong Chen +2 more

The globular C1q receptor is required for epidermal growth factor receptor signaling during Candida albicans infection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.25.445718

N/A

0DataRank · unranked

0 citations

Jianfeng Lin, Norma V. Solis, Michael Eng, Marc Swidergall, Feng Wang +5 more

Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity

Cell Host & Microbe(2022)10.1016/j.chom.2022.02.017

N/A

0DataRank · unranked

67 citations

Chetan V. Jawale, Chunsheng Zhou, Lin Li, Giraldina J Trevejo-Nunez, Syed A. Rahman +8 more

Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102419

N/A

0DataRank · unranked

21 citations

Léa Lortal, Antzela Tsavou, Olivia W. Hepworth, Don N. Wickramasinghe, Jemima Ho +5 more

A gut-oral microbiome–driven axis controls oropharyngeal candidiasis through retinoic acid

JCI Insight(2022)10.1172/jci.insight.160348

N/A

0DataRank · unranked

21 citations

Martinna Bertolini, Chunsheng Zhou, Tiffany C. Taylor, Darryl A. Abbott, Javonn Musgrove +4 more

EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.05.483111

N/A

0DataRank · unranked

1 citations

Léa Lortal, Antzela Tsavou, Olivia W. Hepworth, Don N. Wickramansinghe, Jemima Ho +5 more

Arid5a mediates an IL-17-dependent pathway that drives autoimmunity but not antifungal host defense

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.14.480386

N/A

0DataRank · unranked

0 citations

Yang Li, Dedong Li, Saikat Majumder, Mandy J. McGeachy, Partha S. Biswas +3 more

When IL-17 gets on your nerves

Cell(2023)10.1016/j.cell.2022.12.048

N/A

0DataRank · unranked

12 citations

Woan-Yu Lin, Sarah L. Gaffen, Iliyan D. Iliev

Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs

PLoS Pathogens(2024)10.1371/journal.ppat.1012302

N/A

0DataRank · unranked

16 citations

Martinna Bertolini, Bianca M. Coleman, Tiffany C. Taylor, Nicole O. Ponde, Sarah L. Gaffen +1 more

Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.08.611873

N/A

0DataRank · unranked

4 citations

Jinendiran Sekar, Norma V. Solis, Antoine Millet, Felix E.Y. Aggor, Asia S. Wildeman +6 more

An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.25.671995

N/A

0DataRank · unranked

0 citations

Melissa E. Cook, Md. Robin Khan, Amanda K. Vogel, Anthony J. Wells, Jian Miao +10 more

The RNA binding protein Arid5a is an activator of TNF signaling in rheumatoid arthritis

JCI Insight(2026)10.1172/jci.insight.196411

N/A

0DataRank · unranked

0 citations

Ipsita Dey, Shachi P. Vyas, Alzbeta Synackova, Decheng Li, Erik Lubberts +6 more

Epitranscriptomic control of host epithelial responses to candidiasis via N6-Methyladenosine (m 6 A) methylation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.07.674635

N/A

0DataRank · unranked

0 citations

Ipsita Dey, Tiffany C. Taylor, Melissa E. Cook, Bianca M. Coleman, Rami Bechara +2 more

A loss-of-function mutation in IL-17F enhances susceptibility of mice to oropharyngeal candidiasis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.09.028027

N/A

0DataRank · unranked

1 citations

Leticia Monin, Rachael A. Gordon, Felix E.Y. Aggor, Rami Bechara, Tara N. Edwards +4 more

The metabolism-modulating activity of IL-17 signaling in health and disease

The Journal of Experimental Medicine(2021)10.1084/jem.20202191

N/A

0DataRank · unranked

97 citations

Mandy J. McGeachy, Sarah L. Gaffen, Rami Bechara

Local Sustained Delivery of Anti–IL-17A Antibodies Limits Inflammatory Bone Loss in Murine Experimental Periodontitis

The Journal of Immunology(2021)10.4049/jimmunol.2001432

N/A

0DataRank · unranked

33 citations

K. L. M. Maltos, Mostafa Shehabeldin, Laura L. Thomas, Zhe Zhuang, Sayuri Yoshizawa +6 more

The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation

JCI Insight(2021)10.1172/jci.insight.152766

N/A

0DataRank · unranked

20 citations

Nilesh Amatya, Saikat Majumder, Chunsheng Zhou, Yang Li, Qixing Liu +3 more

The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection

mBio(2021)10.1128/mbio.02716-21

N/A

0DataRank · unranked

19 citations

Jianfeng Lin, Norma V. Solis, Michael Eng, Marc Swidergall, Feng Wang +5 more

RTEC-intrinsic IL-17–driven inflammatory circuit amplifies antibody-induced glomerulonephritis and is constrained by Regnase-1

JCI Insight(2021)10.1172/jci.insight.147505

N/A

0DataRank · unranked

11 citations

Rami Bechara, Kritika Ramani, Chetan V. Jawale, Yang Li, Jay K. Kolls +3 more

‘(m6)A’ stands for ‘autoimmunity’: reading, writing, and erasing RNA modifications during inflammation

Trends in Immunology(2021)10.1016/j.it.2021.10.002

N/A

0DataRank · unranked

16 citations

Sarah L. Gaffen, Rami Bechara