Alex Sigal

ORCID: 0000-0001-8571-2004

Also affiliated with Africa Health Research Institute, University of KwaZulu-Natal

MedicineImmunology and MicrobiologyMathematics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.3Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A high‐resolution 3D atlas of the spectrum of tuberculous and COVID‐19 lung lesions

EMBO Molecular Medicine(2022)10.15252/emmm.202216283

Top 27%

0.754DataRank

Top 27%21 citations

Joel N. Glasgow, Kievershen Nargan, Kapongo Lumamba, Rajhmun Madansein, Kameel Maharaj +20 more

Papers

Driven by 42 papers — median percentile 69. Top paper: “Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant”.

Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant

New England Journal of Medicine(2021)10.1056/nejmoa2102214

N/A

13.3DataRank · unranked

1321 citations

Vicky L. Baillie, Clare Cutland, Merryn Voysey, Anthonet Koen, Lee Fairlie +46 more

Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

Nature Communications(2021)10.1038/s41467-021-25167-5

N/A

5.7DataRank · unranked

191 citations

Adam Harding, Javier Gilbert‐Jaramillo, Michael L. Knight, Stéphanie Longet, Anthony Brown +92 more

A high‐resolution 3D atlas of the spectrum of tuberculous and COVID‐19 lung lesions

EMBO Molecular Medicine(2022)10.15252/emmm.202216283

Top 27%

0.754DataRank

Top 27%21 citations

Joel N. Glasgow, Kievershen Nargan, Kapongo Lumamba, Rajhmun Madansein, Kameel Maharaj +20 more

SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations

Virus Evolution(2023)10.1093/ve/vead075

N/A

0.544DataRank · unranked

13 citations

Yashica Ganga, Hylton Rodel, Houriiyah Tegally, Afrah Khairallah, Laurelle Jackson +15 more

Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays

Science Translational Medicine(2024)10.1126/scitranslmed.adl1722

Top 36%

0.541DataRank

Top 36%15 citations

Samuel Wilks, Lauren Baracco, Meriem Bekliz, Juan Manuel Carreño, Victor M. Corman +41 more

Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.27.559689

N/A

0.301DataRank · unranked

4 citations

Samuel Wilks, Lauren Baracco, Meriem Bekliz, Juan Manuel Carreño, Victor M. Corman +41 more

Safety and efficacy of the ChAdOx1 nCoV-19 (AZD1222) Covid-19 vaccine against the B.1.351 variant in South Africa

medRxiv(2021)10.1101/2021.02.10.21251247

N/A

0DataRank · unranked

122 citations

Vicky L. Baillie, Clare Cutland, Merryn Voysey, Anthonet Koen, Lee Fairlie +48 more

SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron

medRxiv(2021)10.1101/2021.12.26.21268380

N/A

0DataRank · unranked

72 citations

Marius B. Tincho, Amkele Ngomti, Richard Baguma, Ntombi Benede, Akiko Suzuki +37 more

A meta-analysis of Early Results to predict Vaccine efficacy against Omicron

medRxiv(2021)10.1101/2021.12.13.21267748

N/A

0DataRank · unranked

60 citations

Megan Steain, James A. Triccas, Alex Sigal, Miles P. Davenport, Deborah Cromer +1 more

Two doses of SARS-CoV-2 vaccination induce more robust immune responses to emerging SARS-CoV-2 variants of concern than does natural infection.

Research Square(2021)10.21203/rs.3.rs-226857/v2

N/A

0DataRank · unranked

24 citations

Adam Harding, Javier Gilbert‐Jaramillo, Michael L. Knight, Stéphanie Longet, Anthony Brown +28 more

SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity

medRxiv(2021)10.1101/2021.09.14.21263564

N/A

0DataRank · unranked

23 citations

Farina Karim, Gila Lustig, James Emmanuel San, Tandile Hermanus, Houriiyah Tegally +24 more

A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.12.464114

N/A

0DataRank · unranked

15 citations

Tyler N. Starr, Rachel Eguia, Andrea N. Loes, Khadija Khan, Farina Karim +9 more

HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.25.428084

N/A

0DataRank · unranked

1 citations

Maitreyi Shivkumar, Dejan Mesner, Laura J. Pallett, José Afonso Guerra‐Assunção, Rajhmun Madansein +9 more

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

Nature(2022)10.1038/s41586-022-04460-3

N/A

0DataRank · unranked

623 citations

Marius B. Tincho, Amkele Ngomti, Richard Baguma, Ntombi Benede, Akiko Suzuki +42 more

SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape

Cell Host & Microbe(2022)10.1016/j.chom.2022.01.005

N/A

0DataRank · unranked

241 citations

Farina Karim, Gila Lustig, James Emmanuel San, Tandile Hermanus, Houriiyah Tegally +23 more

Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection

Nature Communications(2022)10.1038/s41467-022-32396-9

N/A

0DataRank · unranked

187 citations

Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy +30 more

Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function

Molecular Biology and Evolution(2022)10.1093/molbev/msac061

N/A

0DataRank · unranked

123 citations

Spyros Lytras, Alexander G. Lucaci, Wolfgang Maier, Björn Grüning, Stephen D. Shank +33 more

Omicron infection enhances Delta antibody immunity in vaccinated persons

Nature(2022)10.1038/s41586-022-04830-x

N/A

0DataRank · unranked

89 citations

Farina Karim, Sandile Cele, Kajal Reedoy, James Emmanuel San, Gila Lustig +52 more

A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy

PLoS Pathogens(2022)10.1371/journal.ppat.1010248

N/A

0DataRank · unranked

80 citations

Tyler N. Starr, Rachel Eguia, Andrea N. Loes, Khadija Khan, Farina Karim +9 more

SARS-CoV-2 Omicron variant emerged under immune selection

Nature Microbiology(2022)10.1038/s41564-022-01246-1

N/A

0DataRank · unranked

59 citations

Wan Ni Chia, Feng Zhu, Barnaby Edward Young, Napaporn Chantasrisawad, Shi-Hsia Hwa +18 more

Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage

Nature Communications(2022)10.1038/s41467-022-29579-9

N/A

0DataRank · unranked

38 citations

Josie Everatt, Daniel G. Amoako, Houriiyah Tegally, Constantinos Kurt Wibmer, Anele Mnguni +40 more

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

PLoS Pathogens(2022)10.1371/journal.ppat.1010592

N/A

0DataRank · unranked

29 citations

Rachel Eguia, Tyler N. Starr, Khadija Khan, Nicholas Franko, Jennifer K. Logue +6 more

HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells

Cell Reports(2022)10.1016/j.celrep.2022.110650

N/A

0DataRank · unranked

27 citations

Dejan Mesner, Maitreyi Shivkumar, Matthew V. X. Whelan, Laura J. Pallett, José Afonso Guerra‐Assunção +10 more

Omicron sub-lineages BA.4/BA.5 escape BA.1 infection elicited neutralizing immunity

medRxiv(2022)10.1101/2022.04.29.22274477

N/A

0DataRank · unranked

86 citations

Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy +27 more

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.12.484088

N/A

0DataRank · unranked

7 citations

Rachel Eguia, Tyler N. Starr, Khadija Khan, Nicholas Franko, Jennifer K. Logue +6 more

SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual

medRxiv(2022)10.1101/2022.11.23.22282673

N/A

0DataRank · unranked

7 citations

Yashica Ganga, Hylton Rodel, Houriiyah Tegally, Laurelle Jackson, Sandile Cele +12 more

SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants

Stem Cell Reports(2023)10.1016/j.stemcr.2023.01.011

N/A

0DataRank · unranked

14 citations

Samantha Little, Kayla Kulhanek, Mélia Magnen, Kriti Bahl, Oghenekevwe M. Gbenedio +37 more

Dynamics of SARS-CoV-2 VOC Neutralization and Novel mAb Reveal Protection against Omicron

Viruses(2023)10.3390/v15020530

N/A

0DataRank · unranked

9 citations

Tien-Ying Hsiang, Ronit R. Dalmat, Reneé C. Ireton, Jennifer F. Morton, Caleb Stokes +20 more

Tuberculosis and COVID-19 in the elderly: factors driving a higher burden of disease

Frontiers in Immunology(2023)10.3389/fimmu.2023.1250198

N/A

0DataRank · unranked

7 citations

Jordi B. Torrelles, Alex Sigal, Anna Allué‐Guardia

Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants

medRxiv(2023)10.1101/2023.11.20.23298785

N/A

0DataRank · unranked

5 citations

Jinal N. Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma +51 more

SARS-CoV-2 viral replication persists in the human lung for several weeks after symptom onset

medRxiv(2023)10.1101/2023.03.06.23286834

N/A

0DataRank · unranked

1 citations

Shameem Z. Jaumdally, Lindsay Wilson, Alwyn Kotzé, Lisa Semple, Stuart Meier +31 more

SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset

American Journal of Respiratory and Critical Care Medicine(2024)10.1164/rccm.202308-1438oc

N/A

0DataRank · unranked

14 citations

Shameem Z. Jaumdally, Lindsay Wilson, Andrea Kotze, Lynn Semple, Stuart Meier +31 more

Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants

PLOS Global Public Health(2024)10.1371/journal.pgph.0002703

N/A

0DataRank · unranked

12 citations

Jinal N. Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma +51 more

eLife Assessment: Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

(2024)10.7554/elife.95964.1.sa2

N/A

0DataRank · unranked

0 citations

Alex Sigal

eLife Assessment: Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

(2025)10.7554/elife.95964.3.sa2

N/A

0DataRank · unranked

0 citations

Alex Sigal

HIV cell-to-cell spread slows evolution of drug resistance

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.04.283192

N/A

0DataRank · unranked

0 citations

Sandile Cele, Laurelle Jackson, Jennifer Giandhari, Túlio de Oliveira, Gila Lustig +2 more

Cerebrospinal Fluid Proteomics Reveals Inflammatory Activation in Aneurysmal Subarachnoid Hemorrhage Irrespective of HIV Status

medRxiv(2025)10.1101/2025.09.30.25337004

N/A

0DataRank · unranked

0 citations

Gila Lustig, Victoria Sviridchik, Zesuliwe Jule, Mallory Bernstein, Kajal Reedoy +9 more

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

Cell(2021)10.1016/j.cell.2021.03.013

N/A

0DataRank · unranked

1545 citations

Evan C. Lam, Kerri St. Denis, Adam D. Nitido, Zeidy H. Garcia, Blake M. Hauser +10 more

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

Nature(2021)10.1038/s41586-021-04387-1

N/A

0DataRank · unranked

1193 citations

Laurelle Jackson, David S. Khoury, Khadija Khan, Thandeka Moyo-Gwete, Houriiyah Tegally +58 more

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

Nature(2021)10.1038/d41586-021-03824-5

N/A

0DataRank · unranked

188 citations

Laurelle Jackson, David S. Khoury, Khadija Khan, Thandeka Moyo-Gwete, Houriiyah Tegally +29 more

HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens

Cell Host & Microbe(2021)10.1016/j.chom.2021.05.012

N/A

0DataRank · unranked

115 citations

Elena Giorgi, Srirupa Chakraborty, Kien Nguyen, Tanmoy Bhattacharya, James Theiler +51 more

SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection

medRxiv(2021)10.1101/2021.12.08.21267417

N/A

0DataRank · unranked

366 citations

Laurelle Jackson, David S. Khoury, Khadija Khan, Thandeka Moyo-Gwete, Houriiyah Tegally +29 more

Alex Sigal

Indexed papers

Top data-sharing exemplar

Papers