🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Farren J. Isaacs

Yale University

ORCID: 0000-0001-8615-8236

Also affiliated with Systems Biology Institute

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 15 papers. Top paper: “Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations”.

Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations

ACS Central Science(2021)10.1021/acscentsci.1c00039

N/A

0.834DataRank · unranked

259 citations

Elizabeth A. Stone, M.G. Deshmukh, Joseph A. Ippolito, Mohammad Mehdi Ghahremanpour, Julian Tirado‐Rives +11 more

DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.20.305359

N/A

0DataRank · unranked

1 citations

Ane Landajuela, Ravikiran Kasula, Wenjiao Zhou, John T. Powell, Zhiqun Xi +6 more

Hydrogel-based biocontainment of bacteria for continuous sensing and computation

Nature Chemical Biology(2021)10.1038/s41589-021-00779-6

N/A

0DataRank · unranked

248 citations

Eléonore Tham, Xinyue Liu, Kevin Yehl, Alexis J. Rovner, Hyunwoo Yuk +5 more

Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency

ACS Medicinal Chemistry Letters(2021)10.1021/acsmedchemlett.1c00326

N/A

0DataRank · unranked

57 citations

Krasimir A. Spasov, R. Reilly, Klarissa Hollander, Elizabeth A. Stone, Joseph A. Ippolito +11 more

Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function

Cell Reports(2021)10.1016/j.celrep.2021.109416

N/A

0DataRank · unranked

28 citations

Natasha L. Pirman, Kyle Mohler, Pierre A. Miranda-Herrera, Natanael Zarco, Onur Kilic +13 more

Chemoselective restoration of para-azido-phenylalanine at multiple sites in proteins

Cell chemical biology(2021)10.1016/j.chembiol.2021.12.002

N/A

0DataRank · unranked

7 citations

Koen Vanderschuren, Adrian D. Haimovich, Anushka Halder, Kallol Gupta, Jesse Rinehart +2 more

Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis

Nature Communications(2022)10.1038/s41467-022-28206-x

N/A

0DataRank · unranked

72 citations

Gunasheil Mandava, Sibel Ebru Yalcin, Pol Arranz‐Gibert, Peter Dahl, Catharine Shipps +10 more

Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiome

Cell(2022)10.1016/j.cell.2022.03.008

N/A

0DataRank · unranked

50 citations

Joonseok Oh, Shenqi Wang, Jason M. Crawford, Farren J. Isaacs, Jaymin R. Patel

Targeted editing and evolution of engineered ribosomes in vivo by filtered editing

Nature Communications(2022)10.1038/s41467-021-27836-x

N/A

0DataRank · unranked

9 citations

Shane D. Elliott, Alanna Schepartz, Farren J. Isaacs, Felix Radford

Mapping the in vivo fitness landscape of a tethered ribosome

Science Advances(2023)10.1126/sciadv.ade8934

N/A

0DataRank · unranked

4 citations

Jesse Rinehart, Farren J. Isaacs, Felix Radford

Enhanced eMAGE applied to identify genetic factors of nuclear hormone receptor dysfunction via combinatorial gene editing

Nature Communications(2024)10.1038/s41467-024-49365-z

N/A

0DataRank · unranked

8 citations

Zhuobin Liang, Anabel Y. Schweitzer, Eli Metzner, Farren J. Isaacs, Peter N. Ciaccia

Engineering a genomically recoded organism with one stop codon

Nature(2025)10.1038/s41586-024-08501-x

N/A

0DataRank · unranked

42 citations

Michael T. A. Nguyen, Daniel W. Moonan, Kyle Mohler, Kebron Gurara, Shenqi Wang +13 more

Precision multiplexed base editing in human cells using Cas12a-derived base editors

Nature Communications(2025)10.1038/s41467-025-59653-x

N/A

0DataRank · unranked

7 citations

Etowah W. Adams, Michael T. A. Nguyen, Monkol Lek, Farren J. Isaacs, Anabel Y. Schweitzer

Tough Hydrogel-Based Biocontainment of Engineered Organisms for Continuous, Self-Powered Sensing and Computation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.11.941120

N/A

0DataRank · unranked

9 citations

Eléonore Tham, Xinyue Liu, Kevin Yehl, Alexis J. Rovner, Hyunwoo Yuk +4 more

Engineered orthogonal translation systems from metagenomic libraries expand the genetic code

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.30.685624

N/A

0DataRank · unranked

0 citations

Michael T. A. Nguyen, Petar I. Penev, Jillian F. Banfield, Farren J. Isaacs, Michael C. Jewett +1 more