Brian Button

University of North Carolina at Chapel Hill

Also affiliated with Lung Institute

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 25 papers. Top paper: “CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium”.

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium

PLoS Biology(2009)10.1371/journal.pbio.1000155

N/A

0.791DataRank · unranked

194 citations

Brian Button, Sherif E. Gabriel, Susan Burkett, Yu Yan, Mario H. Skiadopoulos +8 more

Global warming risks dehydrating and inflaming human airways

Communications Earth & Environment(2025)10.1038/s43247-025-02161-z

N/A

0.373DataRank · unranked

11 citations

Aurélie Edwards, Dan Li, Linying Wang, Kian Fan Chung, Deen Bhatta +8 more

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium

UNC Libraries(2020)10.17615/shw8-yj37

N/A

0DataRank · unranked

9 citations

Tristan R. McKay, Yu Yan, Brian Button, Yan L. Dang, Leatrice Vogel +8 more

Mathematical Model of Nucleotide Regulation on Airway Epithelia: IMPLICATIONS FOR AIRWAY HOMEOSTASIS

UNC Libraries(2020)10.17615/n14t-n208

N/A

0DataRank · unranked

2 citations

Timothy C. Elston, Peiying Zuo, Richard C. Boucher, Maryse Picher, Brian Button +2 more

The in vitro effect of nebulised hypertonic saline on human bronchial epithelium

UNC Libraries(2020)10.17615/sytb-ag68

N/A

0DataRank · unranked

1 citations

Dan Wu, Jennifer L. Goralski, W.R. Thelin, R. C. Boucher, Brian Button

BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.17.155846

N/A

0DataRank · unranked

2 citations

Matthew R. Markovetz, Cameron B. Morrison, Kathryn M. McFadden, Troy D. Rogers, Brian Button +5 more

Roles of mucus adhesion and cohesion in cough clearance

UNC Libraries(2020)10.17615/an1y-4z26

N/A

0DataRank · unranked

0 citations

Michael Rubinstein, Richard C. Boucher, Robert G. Dennis, Eyad Atieh, Nathan T. Shenkute +7 more

The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis

UNC Libraries(2020)10.17615/3v68-0a83

N/A

0DataRank · unranked

0 citations

Bahjat F. Qaqish, Michael Rubinstein, Wayne H. Anderson, Neil E. Alexis, C. William Davis +13 more

Mucociliary Clearance in Mice Measured by Tracking Trans-tracheal Fluorescence of Nasally Aerosolized Beads

UNC Libraries(2020)10.17615/skjg-6c02

N/A

0DataRank · unranked

0 citations

Alessandra Livraghi-Butrico, Lawrence E. Ostrowski, Brian Button, Barbara R. Grubb, Troy D. Rogers

Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure

UNC Libraries(2020)10.17615/n4ex-wt40

N/A

0DataRank · unranked

0 citations

Brian Button, Margaret W. Leigh, Mehmet Kesımer, John K. Sheehan, Li‐Heng Cai +8 more

Airway surface liquid pH is not acidic in children with cystic fibrosis

UNC Libraries(2020)10.17615/h0wj-sj28

N/A

0DataRank · unranked

0 citations

Ingo Klimant, Brian Button, Samuel Montgomery, Thien Nguyen, André Schultz +8 more

Airway Surface Liquid Volume Regulation Determines Different Airway Phenotypes in Liddle Compared with βENaC-overexpressing Mice

UNC Libraries(2020)10.17615/g7w0-jv62

N/A

0DataRank · unranked

0 citations

Wanda K. O’Neal, Carsten Schultz, Alessandra Livraghi, Ray A. Caldwell, Marcus Mall +9 more

Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic Phenotype

UNC Libraries(2020)10.17615/0rky-5784

N/A

0DataRank · unranked

57 citations

Wayne H. Anderson, Brian Button, Richard C. Boucher

Airway Epithelial Nucleotide Release Contributes to Mucociliary Clearance

Life(2021)10.3390/life11050430

N/A

0DataRank · unranked

12 citations

Barbara R. Grubb, Brian Button, Eduardo R. Lazarowski, Catharina van Heusden

Probing biological nanotopology via diffusion of weakly constrained plasmonic nanorods with optical coherence tomography

UNC Libraries(2021)10.17615/mnzf-zt07

N/A

0DataRank · unranked

0 citations

Wei‐Chen Wu, Brian Button, Patricia Casbas-Hernández, David B. Hill, Changhuei Yang +5 more

Hyperconcentrated Mucus Unifies Submucosal Gland and Superficial Airway Dysfunction in Cystic Fibrosis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.22.461306

N/A

0DataRank · unranked

0 citations

Giorgia Radicioni, Micah Papanikolas, Georgi Stoychev, Matthew R. Markovetz, Kazuhiro Aoki +25 more

Role of mechanical stress in regulating airway surface hydration and mucus clearance rates

UNC Libraries(2021)10.17615/vy7s-yd16

N/A

0DataRank · unranked

0 citations

Richard C. Boucher, Brian Button

Differential effects of cyclic and constant stress on ATP release and mucociliary transport by human airway epithelia: Role of cyclic stress in airway mucociliary transport

UNC Libraries(2021)10.17615/4883-bm69

N/A

0DataRank · unranked

0 citations

Maryse Picher, Richard C. Boucher, Brian Button

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection

Nature Genetics(2022)10.1038/s41588-022-01131-x

N/A

0DataRank · unranked

144 citations

Sylvia A. Sarnik, Eleanor Wang, James Zengel, Sarah R. Leist, Alexandra Schäfer +45 more

Mucus-targeting therapies of defective mucus clearance for cystic fibrosis: A short review

Current Opinion in Pharmacology(2022)10.1016/j.coph.2022.102248

N/A

0DataRank · unranked

18 citations

Carla M. P. Ribeiro, Brian Button, Miriam Frankenthal Figueira

STAT3-Dependent Regulation of CFTR and Ciliogenesis Is Essential for Mucociliary Clearance and Innate Airway Defense in Hyper-IgE Syndrome

American Journal of Respiratory and Critical Care Medicine(2025)10.1164/rccm.202407-1415oc

N/A

0DataRank · unranked

4 citations

Samantha A. Walls, Hong Dang, Nancy L. Quinney, Patrick R Sears, Taraneh Sadritabrizi +35 more

Hyaluronan Ameliorates Viral Pneumonia in Mice and Humans by Inhibiting Transcription Factor E2F1

American Journal of Respiratory Cell and Molecular Biology(2025)10.1165/rcmb.2025-0173oc

N/A

0DataRank · unranked

3 citations

Carol S. Trempus, Flavia Galdi, Negin P. Martin, Wesley Gladwell, Michael J. Cronce +29 more

Heat waves elevate risks of airway hypersensitivity that inhaled endogenous ions reduce

Research Square(2025)10.21203/rs.3.rs-6839331/v1

N/A

0DataRank · unranked

0 citations

Brian Button, Aurélie Edwards, Kian Fan Chung, Hong Dang, Mark I. Gutay +8 more

A mechanochemical model for auto-regulation of lung airway surface layer volume

UNC Libraries(2020)10.17615/gn4w-3252

N/A

0DataRank · unranked

0 citations

M. Gregory Forest, Brandon Lindley, Robert Tarran, Guilherme J. M. Garcia, Brian Button +3 more

Normal and Cystic Fibrosis Airway Surface Liquid Homeostasis: THE EFFECTS OF PHASIC SHEAR STRESS AND VIRAL INFECTIONS

UNC Libraries(2020)10.17615/ak4t-v309

N/A

0DataRank · unranked

10 citations

Richard C. Boucher, Raymond J. Pickles, Anthony M. Paradiso, Peter L. Collins, Robert Tarran +6 more