Charles O. Rock

Biochemistry, Genetics and Molecular BiologyNeuroscienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 28 papers. Top paper: “Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition”.

Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition

Nature Chemical Biology(2023)10.1038/s41589-023-01320-7

N/A

1.2DataRank · unranked

38 citations

Chitra Subramanian, Eric M. Bilotta, Leopold Garnar-Wortzel, Anissa R. Ramos, Yuxiang Zhang +5 more

Incorporation of extracellular fatty acids by a fatty acid kinase‐dependent pathway in Staphylococcus aureus

Molecular Microbiology(2014)10.1111/mmi.12556

N/A

0.724DataRank · unranked

124 citations

Matthew W. Frank, Pamela Jackson, Chitra Subramanian, Charles O. Rock, Joshua B. Parsons

Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101676

N/A

0.396DataRank · unranked

13 citations

M.G. Cuypers, Christy R. Grace, Shashank Pant, Chitra Subramanian, Emad Tajkhorshid +3 more

Cryo-EM reconstruction of oleate hydratase bound to a phospholipid membrane bilayer

Journal of Structural Biology(2024)10.1016/j.jsb.2024.108116

N/A

0.269DataRank · unranked

5 citations

M. Zuhaib Qayyum, Ravi Kalathur, Charles O. Rock, Christopher D. Radka, Michael L. Oldham

Metabolic adaptations underpin resistance to histone acetyltransferase inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.12.503669

N/A

0.104DataRank · unranked

1 citations

Chitra Subramanian, Eric M. Bilotta, Leopold Garnar-Wortzel, Anissa R. Ramos, Yuxiang Zhang +5 more

Initiation of Fatty Acid Synthesis by a Malonyl‐ACP Decarboxylase

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.03136

N/A

0DataRank · unranked

0 citations

Charles O. Rock, Sarah Whaley

A bacterial pan-genome makes gene essentiality strain-dependent and evolvable

Nature Microbiology(2022)10.1038/s41564-022-01208-7

N/A

0DataRank · unranked

140 citations

Emily Rudmann, Jien Li, Defne Surujon, Jon Anthony, Matthew W. Frank +6 more

Domain architecture and catalysis of the Staphylococcus aureus fatty acid kinase

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101993

N/A

0DataRank · unranked

16 citations

M.G. Cuypers, Christopher D. Radka, Stephen W. White, Charles O. Rock, Chitra Subramanian

Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102195

N/A

0DataRank · unranked

16 citations

Darcie J. Miller, Matthew W. Frank, Charles O. Rock, Christopher D. Radka

Amino Acid Metabolism Controls Fatty Acid Structure in Staphylococcus aureus

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4125

N/A

0DataRank · unranked

1 citations

Matthew W. Frank, Charles O. Rock, Sarah Whaley

A bacterial pan-genome makes gene essentiality strain-dependent and evolvable

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.08.479609

N/A

0DataRank · unranked

6 citations

Emily Rudmann, Jien Li, Defne Surujon, Jon Anthony, Matthew W. Frank +6 more

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.26.477867

N/A

0DataRank · unranked

2 citations

Federico Rosconi, Bharathi Sundaresh, Emily Rudmann, Luisa María Nieto Ramírez, Andrew T. Nishimoto +12 more

Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101434

N/A

0DataRank · unranked

25 citations

Christopher D. Radka, Chitra Subramanian, Matthew W. Frank, Charles O. Rock, Sarah Whaley

A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.103036

N/A

0DataRank · unranked

17 citations

Matthew W. Frank, Charles O. Rock, Sarah Whaley

The Phospholipase A1 Activity of Glycerol Ester Hydrolase (Geh) Is Responsible for Extracellular 2-12( S )-Methyltetradecanoyl-Lysophosphatidylglycerol Production in Staphylococcus aureus

mSphere(2023)10.1128/msphere.00031-23

N/A

0DataRank · unranked

10 citations

Matthew W. Frank, My-Kyung Yun, Charles O. Rock, Chitra Subramanian

Lysophosphatidylglycerol (LPG) phospholipase D maintains membrane homeostasis in Staphylococcus aureus by converting LPG to lysophosphatidic acid

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104863

N/A

0DataRank · unranked

6 citations

Mi‐Kyung Yun, Matthew M. Frank, Charles O. Rock, Chitra Subramanian

Vaginal Lactobacillus fatty acid response mechanisms reveal a metabolite-targeted strategy for bacterial vaginosis treatment

Cell(2024)10.1016/j.cell.2024.07.029

N/A

0DataRank · unranked

57 citations

Matthew W. Frank, Christopher D. Radka, Sarah Jeanfavre, Jiawu Xu, Megan W. Tse +19 more

Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis

Journal of Structural Biology(2024)10.1016/j.jsb.2024.108065

N/A

0DataRank · unranked

9 citations

Charles O. Rock, Christopher D. Radka

Staphylococcus aureus oleate hydratase produces ligands that activate host PPARα

Frontiers in Cellular and Infection Microbiology(2024)10.3389/fcimb.2024.1352810

N/A

0DataRank · unranked

9 citations

Matthew W. Frank, T. Simmons, Cydney N. Johnson, Jason W. Rosch, Charles O. Rock +1 more

Development of Brain Penetrant Pyridazine Pantothenate Kinase Activators

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01211

N/A

0DataRank · unranked

5 citations

Chitra Subramanian, Mi‐Kyung Yun, Anne Edwards, Lalit Sharma, Lei Yang +7 more

The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.105627

N/A

0DataRank · unranked

9 citations

Christy R. Grace, Hale S. Hasdemir, Yupeng Li, Carlos C. Rodríguez, Patrick Fernandes Rodrigues +8 more

HtrA, fatty acids, and membrane protein interplay in Chlamydia trachomatis to impact stress response and trigger early cellular exit

Journal of Bacteriology(2024)10.1128/jb.00371-23

N/A

0DataRank · unranked

3 citations

Laurence Don Wai Luu, Vanissa A. Ong, Bryan A. Wee, Matthew J. A. Phillips, Laura C. McCaughey +9 more

The Bacillus subtilis cell envelope stress-inducible ytpAB operon modulates membrane properties and contributes to bacitracin resistance

Journal of Bacteriology(2024)10.1128/jb.00015-24

N/A

0DataRank · unranked

2 citations

Yesha Patel, Briana E. Arquilevich, Chitra Subramanian, Matthew W. Frank, Charles O. Rock +2 more

The Bacillus subtilis cell envelope stress-inducible ytpAB operon modulates membrane properties and contributes to bacitracin resistance

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.17.576085

N/A

0DataRank · unranked

0 citations

Yesha Patel, Briana E. Arquilevich, Chitra Subramanian, Matthew W. Frank, Charles O. Rock +2 more

LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116504

N/A

0DataRank · unranked

8 citations

Mi Kyung Yun, Chitra Subramanian, Rajendra Tangallapally, Suzanne Jackowski, Charles O. Rock +3 more

A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2020)10.1016/j.bbadis.2020.165663

N/A

0DataRank · unranked

38 citations

Jiangwei Yao, Matthew W. Frank, Charles O. Rock, Suzanne Jackowski, Chitra Subramanian

Structural transitions permitting ligand entry and exit in bacterial fatty acid binding proteins

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.16.460654

N/A

0DataRank · unranked

1 citations

M.G. Cuypers, Christy R. Grace, Shashank Pant, Chitra Subramanian, Emad Tajkhorshid +3 more

Structure and mechanism of Staphylococcus aureus oleate hydratase (OhyA)

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.00367

N/A

0DataRank · unranked

0 citations

Justin L. Batte, Matthew W. Frank, Brandon Young, Charles O. Rock, Christopher D. Radka