Mitchell A. Lazar

Also affiliated with University of Pennsylvania

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.7Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits

Cell Metabolism(2023)10.1016/j.cmet.2023.03.001

Top 8%

2.7DataRank

Top 8%136 citations

Marcin von Grotthuss, Jeffrey Massung, Dongkeun Jang, Lizz Caulkins, Ryan Koesterer +82 more

Papers

Driven by 41 papers — median percentile 92. Top paper: “Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway”.

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

Genes & Development(2000)10.1101/gad.14.1.45

N/A

13.2DataRank · unranked

331 citations

Jinsong Zhang, Eric A. Miska, Matthew G. Guenther, Tony Kouzarides, Mitchell A. Lazar +1 more

Proteasomal regulation of nuclear receptor corepressor-mediated repression

Genes & Development(1998)10.1101/gad.12.12.1775

N/A

12.3DataRank · unranked

223 citations

Matthew G. Guenther, Richard W. Carthew, Mitchell A. Lazar, Jinsong Zhang

Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex

Genes & Development(2002)10.1101/gad.1037502

N/A

6.0DataRank · unranked

135 citations

Jiujiu Yu, Gary D. Kao, Tim J. Yen, Mitchell A. Lazar, Matthew G. Guenther

Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex

Proceedings of the National Academy of Sciences(1997)10.1073/pnas.94.26.14400

N/A

5.8DataRank · unranked

136 citations

Jessica Dawson, Robert M. Lavinsky, Christopher K. Glass, Michael G. Rosenfeld, Mitchell A. Lazar +1 more

Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors

Proceedings of the National Academy of Sciences(2005)10.1073/pnas.0500299102

N/A

4.4DataRank · unranked

95 citations

James D. Love, Yun Li, Mitchell A. Lazar, David Neuhaus, John W. R. Schwabe +1 more

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits

Cell Metabolism(2023)10.1016/j.cmet.2023.03.001

Top 8%

2.7DataRank

Top 8%136 citations

Marcin von Grotthuss, Jeffrey Massung, Dongkeun Jang, Lizz Caulkins, Ryan Koesterer +82 more

The Nuclear Receptor Corepressor Deacetylase Activating Domain Is Essential for Repression by Thyroid Hormone Receptor

Molecular Endocrinology(2005)10.1210/me.2005-0009

N/A

1.8DataRank · unranked

52 citations

Mitchell A. Lazar, Takahiro Ishizuka

Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

Science(2007)10.1126/science.1150179

N/A

0.985DataRank · unranked

711 citations

Nan Wu, Joshua C. Curtin, Mohammed Qatanani, Nava R. Szwergold, Robert A. Reid +7 more

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

Science(2011)10.1126/science.1198125

N/A

0.978DataRank · unranked

676 citations

Tao Liu, Zheng Sun, Anne Bugge, Shannon E. Mullican, Theresa Alenghat +3 more

The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

Molecular and Cellular Biology(2001)10.1128/mcb.21.18.6091-6101.2001

N/A

0.961DataRank · unranked

605 citations

Orr Barak, Mitchell A. Lazar, Matthew G. Guenther

Hepatic vagal afferents convey clock-dependent signals to regulate circadian food intake

Science(2024)10.1126/science.adn2786

N/A

0.564DataRank · unranked

42 citations

Lily C. Melink, Mohit Midha, Alan de Araujo, Caroline E. Geisler, Ahren J. Alberto +6 more

RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure

Journal of Clinical Investigation(2023)10.1172/jci162309

N/A

0.464DataRank · unranked

21 citations

Santosh K. Maurya, Elizabeth Pruzinsky, Kirill Batmanov, Yang Xiao, Sarah M. Sulon +13 more

Nicotinamide Riboside Improves Cardiac Function and Prolongs Survival After Disruption of the Cardiomyocyte Clock

Frontiers in Molecular Medicine(2022)10.3389/fmmed.2022.887733

N/A

0.406DataRank · unranked

14 citations

Bryce J. Carpenter, Isaac J. Celwyn, Daniel P. Kelly, Joseph A. Baur, Mitchell A. Lazar +1 more

Balanced control of thermogenesis by nuclear receptor corepressors in brown adipose tissue

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2205276119

N/A

0.345DataRank · unranked

9 citations

Amy K. Hauck, Kirill Batmanov, Shin‐ichi Inoue, Bethany Nahri So, Mindy Kim +4 more

The Circadian Regulation of Nutrient Metabolism in Diet-Induced Obesity and Metabolic Disease

Nutrients(2022)10.3390/nu14153136

N/A

0DataRank · unranked

20 citations

Kaan T. Oral, Brianna M. Krusen, Mitchell A. Lazar, Lauren N. Woodie

Phosphorylated MED1 links transcription recycling and cancer growth

Nucleic Acids Research(2022)10.1093/nar/gkac246

N/A

0DataRank · unranked

19 citations

Zhenqing Ye, Raymond E. Soccio, Tomoyoshi Nakadai, William Hankey, Yue Zhao +16 more

Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice

Nature Communications(2023)10.1038/s41467-023-40927-1

N/A

0DataRank · unranked

80 citations

Julie Dimitry, Jong Hee Song, Minsoo Son, Patrick W. Sheehan, Melvin W. King +6 more

Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis

Science Translational Medicine(2023)10.1126/scitranslmed.adc9653

N/A

0DataRank · unranked

69 citations

Kirill Batmanov, Wenxiang Hu, Kun Zhu, Alexander Y. Tom, Dongyin Guan +9 more

An intrinsically disordered region controlling condensation of a circadian clock component and rhythmic transcription in the liver

Molecular Cell(2023)10.1016/j.molcel.2023.09.010

N/A

0DataRank · unranked

49 citations

Isaac J. Celwyn, Dongyin Guan, Xiao Yang, Xiang Wang, Wenxiang Hu +5 more

The REV-ERB Nuclear Receptors: Timekeepers for the Core Clock Period and Metabolism

Endocrinology(2023)10.1210/endocr/bqad069

N/A

0DataRank · unranked

43 citations

Mitchell A. Lazar, Marine Adlanmérini

Hepatocyte SREBP signaling mediates clock communication within the liver

Journal of Clinical Investigation(2023)10.1172/jci163018

N/A

0DataRank · unranked

27 citations

Hosung Bae, Dishu Zhou, Ying Chen, Chunjie Jiang, Cam Mong La +10 more

Hindbrain REV-ERB nuclear receptors regulate sensitivity to diet-induced obesity and brown adipose tissue pathophysiology

Molecular Metabolism(2023)10.1016/j.molmet.2023.101861

N/A

0DataRank · unranked

1 citations

Lily C. Melink, Ahren J. Alberto, Michelle Burrows, Samantha M. Fortin, Calvin C. Chan +3 more

Hepatic Vagal Afferents Convey Clock-Dependent Signals to Regulate Circadian Food Intake

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.30.568080

N/A

0DataRank · unranked

2 citations

Lily C. Melink, Mohit Midha, Alan de Araujo, Caroline E. Geisler, Ahren J. Alberto +6 more

Short-term cold exposure induces persistent epigenomic memory in brown fat

Cell Metabolism(2024)10.1016/j.cmet.2024.05.011

N/A

0DataRank · unranked

37 citations

Matthew J. Emmett, Hee‐Woong Lim, Mohit Midha, Hannah J. Richter, Isaac J. Celwyn +6 more

Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during obesity

Nature Communications(2024)10.1038/s41467-024-49632-z

N/A

0DataRank · unranked

10 citations

Julia Chini, Sam J. McCright, Nicole DeMarco, Jessica Miller, Leonel Joannas +7 more

REV-ERBα regulates brain NAD+ levels and tauopathy via an NFIL3–CD38 axis

Nature Aging(2025)10.1038/s43587-025-00950-x

N/A

0DataRank · unranked

8 citations

Ryeonghwa Kang, Sohui Park, Ibrahim Olabayode Saliu, Maarten J. van Son, Jaymie R. Voorhees +11 more

A non-apoptotic caspase-8–meteorin pathway in hepatocytes promotes MASH fibrosis

Nature Metabolism(2025)10.1038/s42255-025-01355-1

N/A

0DataRank · unranked

7 citations

Mary P. Moore, Hongxue Shi, Yang Xiao, Jiayu Zhang, Lanuza A. P. Faccioli +9 more

Isoform-specific functions of PPARγ in gene regulation and metabolism

Genes & Development(2022)10.1101/gad.349232.121

N/A

0DataRank · unranked

50 citations

Chunjie Jiang, Mindy Kim, Yang Xiao, Hannah J. Richter, Dongyin Guan +7 more

Nuclear receptor coregulator interactions: beyond the switch

Genes & Development(2025)10.1101/gad.353393.125

N/A

0DataRank · unranked

0 citations

Mitchell A. Lazar, Fathima N. Cassim Bawa, F. Nafrisha Cassim Bawa

Dichotomous engagement of HDAC3 activity governs inflammatory responses

Nature(2020)10.1038/s41586-020-2576-2

N/A

0DataRank · unranked

150 citations

Marine Adlanmérini, Amy K. Hauck, Mitchell A. Lazar, Hoang C.B. Nguyen

Transcriptional Control of Circadian Rhythms and Metabolism: A Matter of Time and Space

Endocrine Reviews(2020)10.1210/endrev/bnaa014

N/A

0DataRank · unranked

136 citations

Mitchell A. Lazar, Yong Hoon Kim

Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes

Cell Reports(2020)10.1016/j.celrep.2020.02.023

N/A

0DataRank · unranked

68 citations

Suzanne N. Shapira, Jeff Ishibashi, Samay Sampat, Jaimarie Sostre‐Colón, Matthew J. Emmett +5 more

Hypothalamic REV-ERB nuclear receptors control diurnal food intake and leptin sensitivity in diet-induced obese mice

Journal of Clinical Investigation(2020)10.1172/jci140424

N/A

0DataRank · unranked

54 citations

Hoang C.B. Nguyen, Brianna M. Krusen, Clare W. Teng, Caroline E. Geisler, Lindsey C. Peed +4 more

Nuclear receptors and transcriptional regulation in non-alcoholic fatty liver disease

Molecular Metabolism(2020)10.1016/j.molmet.2020.101119

N/A

0DataRank · unranked

39 citations

Mindy Kim, Mitchell A. Lazar, Yang Xiao

HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity

Genes & Development(2020)10.1101/gad.333674.119

N/A

0DataRank · unranked

34 citations

Fang Liu, Chase Yuan, Deborah Moran, Jeremy Horrell, Heather Gochnauer +9 more

Interconnections between circadian clocks and metabolism

Journal of Clinical Investigation(2021)10.1172/jci148278

N/A

0DataRank · unranked

163 citations

Mitchell A. Lazar, Dongyin Guan

Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids

Cell Metabolism(2021)10.1016/j.cmet.2021.06.004

N/A

0DataRank · unranked

32 citations

Chunjie Jiang, Mindy Kim, Wenjian Yang, Kun Zhu, Dongyin Guan +8 more

Liver Transcriptome Dynamics During Hibernation Are Shaped by a Shifting Balance Between Transcription and RNA Stability

Frontiers in Physiology(2021)10.3389/fphys.2021.662132

N/A

0DataRank · unranked

23 citations

Rui Fu, Kent Riemondy, Jennifer Jager, Bin Fang, Mitchell A. Lazar +2 more

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver

Genes & Development(2021)10.1101/gad.345686.120

N/A

0DataRank · unranked

38 citations

Nagaswaroop Kengunte Nagaraj, Kirill Batmanov, Young‐Wook Cho, Yuxia Guan, Chunjie Jiang +4 more

Modelling metabolic diseases and drug response using stem cells and organoids

Nature Reviews Endocrinology(2022)10.1038/s41574-022-00733-z

N/A

0DataRank · unranked

91 citations

Mitchell A. Lazar, Wenxiang Hu

Circadian Regulation of Gene Expression and Metabolism in the Liver

Seminars in Liver Disease(2022)10.1055/a-1792-4240

N/A

0DataRank · unranked

44 citations

Mitchell A. Lazar, Dongyin Guan

Mitchell A. Lazar

Indexed papers

Top data-sharing exemplar

Papers