Wiesje M. van der Flier

Also affiliated with Alzheimer Nederland, Public Health Service of Amsterdam, Vrije Universiteit Amsterdam

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.4Author DataRank

Indexed papers

10in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 10 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients

Alzheimer s & Dementia(2024)10.1002/alz.13765

Top 25%

0.798DataRank

Top 25%35 citations

Mirthe Coenen, Charles DeCarli, Evan Fletcher, Pauline Maillard, Alzheimer's Disease Neuroimaging Initiative +37 more

Papers

Driven by 61 papers — median percentile 64. Top paper: “Designing the next-generation clinical care pathway for Alzheimer’s disease”.

Designing the next-generation clinical care pathway for Alzheimer’s disease

Nature Aging(2022)10.1038/s43587-022-00269-x

N/A

4.7DataRank · unranked

201 citations

Rhoda Au, Soeren Mattke, Wiesje M. van der Flier, Paul Aisen, Liana G. Apostolova +13 more

A neuroimaging approach to capture cognitive reserve: Application to Alzheimer's disease

Human Brain Mapping(2017)10.1002/hbm.23695

N/A

2.4DataRank · unranked

80 citations

Alle Meije Wink, Colin Groot, Sander C.J. Verfaillie, Jos Twisk, Frederik Barkhof +5 more

The Association Between Biomarkers and Neuropsychiatric Symptoms Across the Alzheimer's Disease Spectrum

American Journal of Geriatric Psychiatry(2020)10.1016/j.jagp.2020.01.012

N/A

2.2DataRank · unranked

71 citations

Inez H.G.B. Ramakers, Sebastian Köhler, Esther E. Bron, Frans R.J. Verhey, Peter Paul De Deyn +7 more

Neuroinflammation in Alzheimer disease

Nature reviews. Immunology(2024)10.1038/s41577-024-01104-7

N/A

0.921DataRank · unranked

464 citations

Frank Jessen, Jeroen Hoozemanns, Dietmar Rudolf Thal, Delphine Boche, Frederic Brosseron +65 more

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

JAMA Neurology(2022)10.1001/jamaneurol.2021.5216

N/A

0.854DataRank · unranked

295 citations

Olin Janssen, Betty M. Tijms, Stephanie J. B. Vos, Rik Ossenkoppele, Pieter Jelle Visser +95 more

Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients

Alzheimer s & Dementia(2024)10.1002/alz.13765

Top 25%

0.798DataRank

Top 25%35 citations

Mirthe Coenen, Charles DeCarli, Evan Fletcher, Pauline Maillard, Alzheimer's Disease Neuroimaging Initiative +37 more

Dementia prevention in memory clinics: recommendations from the European task force for brain health services

The Lancet Regional Health - Europe(2023)10.1016/j.lanepe.2022.100576

N/A

0.781DataRank · unranked

182 citations

Daniele Altomare, Federica Ribaldi, Nicolas Villain, Carol Brayne, Naaheed Mukadam +38 more

Alzheimer’s disease cerebrospinal fluid biomarker in cognitively normal subjects

Brain(2015)10.1093/brain/awv199

N/A

0.745DataRank · unranked

143 citations

Henrik Zetterberg, Argonde C. van Harten, Lidia Glodzik, Pablo Martinez-Lage, Luisella Bocchio-Chiavetto +27 more

Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex

Nature Neuroscience(2025)10.1038/s41593-025-02000-6

N/A

0.736DataRank · unranked

42 citations

Emma M. Coomans, Liana G. Apostolova, Suzanne L. Baker, Henryk Barthel, Thomas G. Beach +92 more

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

Nature Communications(2020)10.1038/s41467-019-13770-6

N/A

0.718DataRank · unranked

119 citations

Rene Pool, Jenny van Dongen, Harmen H. M. Draisma, Jouke‐Jan Hottenga, Gonneke Willemsen +65 more

Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services—part 2 of 6

Alzheimer s Research & Therapy(2021)10.1186/s13195-021-00895-4

N/A

0.706DataRank · unranked

110 citations

Timothy Rittman, Shabina Hayat, Carol Brayne, Frank Jessen, Kaj Blennow +38 more

New landscape of the diagnosis of Alzheimer's disease

The Lancet(2025)10.1016/s0140-6736(25)01294-2

N/A

0.685DataRank · unranked

95 citations

Oskar Hansson, Emma Nichols, Valentina Garibotto, Suzanne E. Schindler, Wiesje M. van der Flier +13 more

Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease

JAMA Neurology(2022)10.1001/jamaneurol.2022.1166

N/A

0.681DataRank · unranked

93 citations

Michaël E. Belloy, Benjamin Grenier‐Boley, Itziar de Rojas, Atahualpa Castillo-Morales, Iris E. Jansen +95 more

Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE)

JAMA Neurology(2022)10.1001/jamaneurol.2022.2262

N/A

0.665DataRank · unranked

83 citations

Wiesje M. van der Flier, Eric E. Smith, Philip M. Bath, Geert Jan Biessels, Emily M. Briceño +27 more

Differential trajectories of hypometabolism across cognitively-defined Alzheimer’s disease subgroups

NeuroImage Clinical(2021)10.1016/j.nicl.2021.102725

Top 31%

0.642DataRank

Top 31%18 citations

Shannon L. Risacher, J.Q. Alida Chen, Ellen Dicks, Andrew J. Saykin, Christine L. Mac Donald +9 more

Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion‐symptom mapping study in 3525 memory clinic patients

Alzheimer s & Dementia(2022)10.1002/alz.12827

N/A

0.624DataRank · unranked

63 citations

Hugo J. Kuijf, Irene M.C. Huenges Wajer, Marco Duering, Frank J. Wolters, Evan F. Fletcher +39 more

Characteristics of subjective cognitive decline associated with amyloid positivity

Alzheimer s & Dementia(2021)10.1002/alz.12512

N/A

0.604DataRank · unranked

55 citations

Willemijn J. Jansen, Stephanie J. B. Vos, Mercè Boada, Lucilla Parnetti, Tomasz Gabryelewicz +58 more

Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease

JAMA Neurology(2025)10.1001/jamaneurol.2025.3217

N/A

0.561DataRank · unranked

41 citations

Shorena Janelidze, Divya Bali, Anna Orduña Dolado, Joseph Therriault, Wagner S. Brum +94 more

Linking self-perceived cognitive functioning questionnaires using item response theory: The subjective cognitive decline initiative.

Neuropsychology(2023)10.1037/neu0000888

Top 36%

0.546DataRank

Top 36%18 citations

the Alzheimer’s Disease Neuroimaging Initiative, Sietske A.M. Sikkes, Douglas Tommet, Richard N. Jones, Paul K. Crane +41 more

MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies

npj Parkinson s Disease(2023)10.1038/s41531-023-00448-6

N/A

0.524DataRank · unranked

32 citations

Konstantinos Poulakis, Rosaleena Mohanty, Christopher G. Schwarz, Scott A. Przybelski, Patricia Diaz‐Galvan +21 more

Predicting Cognitive Decline in Amyloid-Positive Patients With Mild Cognitive Impairment or Mild Dementia

Neurology(2024)10.1212/wnl.0000000000209605

N/A

0.489DataRank · unranked

25 citations

Jeroen Hoogland, Leonie N.C. Visser, Argonde C. van Harten, Hanneke F. Rhodius-Meester, Sietske A.M. Sikkes +7 more

Adherence and intensity in multimodal lifestyle-based interventions for cognitive decline prevention: state-of-the-art and future directions

Alzheimer's Research & Therapy(2025)10.1186/s13195-025-01691-0

N/A

0.477DataRank · unranked

23 citations

Amaia Ayala-Garcia, Mariagnese Barbera, Jenni Lehtisalo, Laura Forcano, Ana Diaz-Ponce +7 more

Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping

Alzheimer s Research & Therapy(2022)10.1186/s13195-022-00962-4

N/A

0.464DataRank · unranked

21 citations

Sarah J. Eger, Yann Le Guen, Vincent Damotte, Shahzad Ahmad, M Arfan Ikram +24 more

Depressive Symptoms and Amyloid Pathology

JAMA Psychiatry(2025)10.1001/jamapsychiatry.2024.4305

N/A

0.464DataRank · unranked

21 citations

Julie Elisabeth Oomens, Sebastiaan Engelborghs, Chris Baeken, Christine A. F. Von Arnim, Mercè Boada +95 more

Development of thresholds and a visualization tool for use of a blood test in routine clinical dementia practice

Alzheimer s & Dementia(2024)10.1002/alz.14088

N/A

0.464DataRank · unranked

21 citations

Jolien Jutte, Maurice Y. Kingma, Sinthujah Vigneswaran, Mariam Gouda, Marie‐Paule van Engelen +16 more

Non‐memory cognitive symptom development in Alzheimer's disease

European Journal of Neurology(2020)10.1111/ene.14185

N/A

0.360DataRank · unranked

10 citations

Wiesje M. van der Flier, David A. Wolk, Manja Lehmann, Robert Howard, Chris Frost +2 more

Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia‐specific perspectives

Alzheimer s & Dementia(2025)10.1002/alz.70536

N/A

0.345DataRank · unranked

9 citations

Reisa A. Sperling, Alicia Algeciras‐Schimnich, Hidenori Arai, Anna M. Barron, Tammie L.S. Benzinger +39 more

Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease

Brain(2025)10.1093/brain/awaf279

N/A

0.330DataRank · unranked

8 citations

Colin Groot, Henryk Barthel, Gérard N. Bischof, Ganna Blazhenets, Ronald Boellaard +71 more

Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.26.559021

Top 56%

0.290DataRank

Top 56%4 citations

Toni Boltz, Marcelo Francia, Merel Bot, N Ramesh, Maria Koromina +10 more

Neurodevelopment and neural environment inform Alzheimer's disease age at onset and phenotype

Alzheimer s & Dementia(2025)10.1002/alz.70668

N/A

0.269DataRank · unranked

5 citations

Rik Ossenkoppele, Neill R. Graff‐Radford, Isabel Elaine Allen, Wendy Shwe, Lynne Rosenberg +23 more

Left-handedness, learning disability, autoimmune disease, and seizure history influence age at onset and phenotypical targeting of Alzheimer’s disease

medRxiv(2022)10.1101/2022.12.17.22283307

N/A

0.241DataRank · unranked

4 citations

Rik Ossenkoppele, Neill R. Graff‐Radford, Isabel Elaine Allen, Wendy Shwe, Lynne Rosenberg +23 more

Evaluation of efficiency and effectiveness of different recruitment strategies for the FINGER‐NL multidomain lifestyle intervention trial via the Dutch Brain Research Registry

Alzheimer's & Dementia: Translational Research & Clinical Interventions(2025)10.1002/trc2.70017

N/A

0.208DataRank · unranked

3 citations

Sietske A. M. Sikkes, Lion M. Soons, Sonja Beers, Yvonne Meijer‐Krommenhoek, Ondine van de Rest +10 more

Challenges at the APOE locus: A robust quality control approach for accurate APOE genotyping

medRxiv(2021)10.1101/2021.10.19.21265022

N/A

0.165DataRank · unranked

2 citations

Sarah J. Eger, Yann Le Guen, Vincent Damotte, Shahzad Ahmad, M Arfan Ikram +24 more

A large-scale multi-centre study characterising atrophy heterogeneity in Alzheimer’s disease

NeuroImage(2025)10.1016/j.neuroimage.2025.121381

Top 70%

0.165DataRank

Top 70%2 citations

Damiano Archetti, Pierrick Bourgeat, Chenyang Jiang, Mara ten Kate, Anna C. van Loenhoud +19 more

Increased genetic protection against Alzheimer’s disease in centenarians

GeroScience(2025)10.1007/s11357-025-01774-8

N/A

0.165DataRank · unranked

2 citations

Zeyuan Song, Amanat Ali, Takashi Sasaki, Niccoló Tesi, Hannah Lords +19 more

GWAS meta-analysis of CSF Alzheimer's disease biomarkers 18,948 individuals reveal novel loci and genes regulating lipid metabolism, brain volume and autophagy

Research Square(2025)10.21203/rs.3.rs-6597595/v1

N/A

0.104DataRank · unranked

1 citations

Jigyasha Timsina, Chenyang Jiang, Daniel L. McCartney, Feifei Tao, Carolina Dalmasso +95 more

Federated Fine-Tuning of SAM-Med3D for MRI-Based Dementia Classification

Lecture notes in computer science(2025)10.1007/978-3-032-05663-4_7

N/A

0.104DataRank · unranked

1 citations

Marawan Elbatel, Janne M. Papma, Geert Jan Biessels, Jurgen A.H.R. Claassen, Huub A. M. Middelkoop +6 more

Comment by European Alzheimer’s Disease Consortium (EADC) investigators on the negative recommendation of the CHMP on the marketing authorization of donanemab for early Alzheimer’ s disease

The Journal of Prevention of Alzheimer s Disease(2025)10.1016/j.tjpad.2025.100259

N/A

0DataRank · unranked

0 citations

Javier Arbizu, Mercè Boada, Mircea Balasa, Karim Bennys, Marina Boban +47 more

Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer’s Disease

Journal of the International Neuropsychological Society(2020)10.1017/s1355617720000934

N/A

0DataRank · unranked

67 citations

Sietske A.M. Sikkes, Rebecca E. Amariglio, Rachel F. Buckley, Michael J Properzi, Gad A. Marshall +10 more

Grey matter network trajectories across the Alzheimer’s disease continuum and relation to cognition

Brain Communications(2020)10.1093/braincomms/fcaa177

N/A

0DataRank · unranked

20 citations

Lisa Vermunt, Wiesje M. van der Flier, Frederik Barkhof, Philip Scheltens, Betty M. Tijms +2 more

Classification of negative and positive 18F-florbetapir brain PET studies in subjective cognitive decline patients using a convolutional neural network

European Journal of Nuclear Medicine and Molecular Imaging(2020)10.1007/s00259-020-05006-3

N/A

0DataRank · unranked

25 citations

Sandeep S.V. Golla, Jarith L. Ebenau, Sander C.J. Verfaillie, Tessa Timmers, Fiona Heeman +7 more

[ 18 F]Flortaucipir PET Across Various MAPT Mutations in Presymptomatic and Symptomatic Carriers

Neurology(2021)10.1212/wnl.0000000000012448

N/A

0DataRank · unranked

51 citations

Janne M. Papma, Sander C.J. Verfaillie, Denise Visser, Emma Weltings, Colin Groot +20 more

Four subgroups based on tau levels in Alzheimer’s disease observed in two independent cohorts

Alzheimer s Research & Therapy(2021)10.1186/s13195-020-00713-3

N/A

0DataRank · unranked

33 citations

Flora H. Duits, Kirsten E. J. Wesenhagen, Laura L. Ekblad, Emma E. Wolters, Eline A.J. Willemse +6 more

Determining the Minimal Important Change of Everyday Functioning in Dementia

Neurology(2022)10.1212/wnl.0000000000200781

N/A

0DataRank · unranked

22 citations

Merike Verrijp, Caroline B. Terwee, Roos J. Jutten, Merel C. Postema, Frederik Barkhof +8 more

Does Loss of Integrity of the Cingulum Bundle Link Amyloid-β Accumulation and Neurodegeneration in Alzheimer’s Disease?

Journal of Alzheimer s Disease(2022)10.3233/jad-220024

N/A

0DataRank · unranked

3 citations

Rik Ossenkoppele, Wiesje M. van der Flier, Huiberdina L. Koek, Yaël D. Reijmer, Laura E.M. Wisse +3 more

MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies

Research Square(2022)10.21203/rs.3.rs-2015284/v1

N/A

0DataRank · unranked

0 citations

Anna Inguanzo, Konstantinos Poulakis, Rosaleena Mohanty, Christopher G. Schwarz, Scott A. Przybelski +21 more

Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts

NeuroImage Clinical(2023)10.1016/j.nicl.2023.103547

N/A

0DataRank · unranked

17 citations

Geert Jan Biessels, Charles DeCarli, Evan F. Fletcher, Pauline Maillard, Frederik Barkhof +36 more

Facilitating clinical use of the Amsterdam Instrumental Activities of Daily Living Questionnaire: Normative data and a diagnostic cutoff value

Journal of the International Neuropsychological Society(2024)10.1017/s1355617724000031

N/A

0DataRank · unranked

7 citations

Mark A. Dubbelman, Jürgen Claesen, Craig Ritchie, Merike Verrijp, Leonie N.C. Visser +5 more

Separating dementia with Lewy bodies from Alzheimer’s disease dementia using a volumetric MRI classifier

European Radiology(2024)10.1007/s00330-024-11257-7

N/A

0DataRank · unranked

3 citations

Antti J Tolonen, Hanneke Rhodius‐Meester, Patrizia Mecocci, Ritva Vanninen, Kristian Steen Frederiksen +7 more

Enhancing Cognitive Performance Prediction through White Matter Hyperintensity Connectivity Assessment: A Multicenter Lesion Network Mapping Analysis of 3,485 Memory Clinic Patients

medRxiv(2024)10.1101/2024.03.28.24305007

N/A

0DataRank · unranked

3 citations

Mirthe Coenen, Charles DeCarli, Alberto De Luca, Ewoud van der Lelij, Alzheimer’s Disease Neuroimaging Initiative +37 more

Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment

Nature Communications(2025)10.1038/s41467-025-56293-z

N/A

0DataRank · unranked

15 citations

Eline A.J. Willemse, Pascual Sánchez‐Juan, Alberto Rábano, Minerva Martínez, James D. Doecke +27 more

SCD‐plus features and AD biomarkers in cognitively unimpaired samples: A meta‐analytic approach for nine cohort studies

Alzheimer s & Dementia(2025)10.1002/alz.14307

N/A

0DataRank · unranked

11 citations

Hannah M Klinger, Rebecca E. Amariglio, Michael Wagner, Frank Jessen, Emrah Düzel +22 more

Enlarged cavum septum pellucidum as a neuroimaging signature of head impact exposure

Brain Communications(2025)10.1093/braincomms/fcaf085

N/A

0DataRank · unranked

6 citations

Hugo L. Hempel, Suzan van Amerongen, Hannah de Bruin, Fleur H C van der Linden, Vikram Venkatraghavan +7 more

CSF proteomic profiles related to cognitive decline in MCI A+ depend on tau levels

Brain(2025)10.1093/brain/awaf251

N/A

0DataRank · unranked

2 citations

Diederick M de Leeuw, Argonde C. van Harten, Charlotte E. Teunissen, Wiesje M. van der Flier, Pieter Jelle Visser +2 more

CHIT1 and DDAH1 levels relate to amyloid-related imaging abnormalities risk profile in Alzheimer’s disease patients

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01799-3

N/A

0DataRank · unranked

2 citations

Everard G.B. Vijverberg, Elena R. Blujdea, Sjors G. J. G. In ‘t Veld, Martín Pucheu Avilés, Sára E. Zsadanyi +11 more

Characterizing visual read tau‐PET‐negative participants with Alzheimer's disease dementia

Alzheimer s & Dementia(2025)10.1002/alz.14423

N/A

0DataRank · unranked

1 citations

Emma M. Coomans, Lotte A. de Koning, Denise Visser, Eline Neutelings, Anouk den Braber +13 more

Cognitive and physical activities are associated with cognitive resilience in a memory clinic cohort

Brain Communications(2025)10.1093/braincomms/fcaf318

N/A

0DataRank · unranked

1 citations

Anna C. van Loenhoud, Bart Kuijper, Ismael Luis Calandri, Colin Groot, Vikram Venkatraghavan +13 more

Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes

Molecular Psychiatry(2025)10.1038/s41380-025-02934-0

N/A

0DataRank · unranked

2 citations

Toni Boltz, Marcelo Francia, Merel Bot, N Ramesh, Maria Koromina +10 more

Increased Genetic Protection Against Alzheimer’s Disease in Centenarians

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.02.657442

N/A

0DataRank · unranked

0 citations

Zeyuan Song, Amanat Ali, Takashi Sasaki, Niccoló Tesi, Hannah Lords +19 more

Associations of lifestyle factors with amyloid pathology in persons without dementia

Journal of Alzheimer s Disease(2025)10.1177/13872877251379083

N/A

0DataRank · unranked

0 citations

Stephanie J. B. Vos, Nancy N. Maserejian, Mercè Boada, Mira Didic, Sebastiaan Engelborghs +95 more

Plasma SNAP25 is increased in pre-clinical Alzheimer's disease and has prognostic value for cognitive decline and disease progression: a multi-cohort study

Research Square(2025)10.21203/rs.3.rs-8249959/v1

N/A

0DataRank · unranked

0 citations

Calvin Trieu, Olivia Belbin, Julie Goossens, Anouk den Braber, Alba Pérez‐Jardón +14 more

Wiesje M. van der Flier

Indexed papers

Top data-sharing exemplar

Papers