Paul J. Hergenrother

Also affiliated with Center for Genomic Science

MedicineBiochemistry, Genetics and Molecular BiologyMaterials Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 36 papers. Top paper: “A Gram-negative-selective antibiotic that spares the gut microbiome”.

A Gram-negative-selective antibiotic that spares the gut microbiome

Nature(2024)10.1038/s41586-024-07502-0

N/A

0.731DataRank · unranked

130 citations

Rebecca J. Ulrich, Archit Vasan, Matt Sinclair, Po‐Chao Wen, Jessica R. Holmes +7 more

A Phosphonate Natural Product Made by Pantoea ananatis is Necessary and Sufficient for the Hallmark Lesions of Onion Center Rot

mBio(2021)10.1128/mbio.03402-20

N/A

0.604DataRank · unranked

55 citations

Lucia Furiassi, Paul J. Hergenrother, William W. Metcalf, Alexander L. A. Polidore

Role of internal loop dynamics in antibiotic permeability of outer membrane porins

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2117009119

N/A

0.568DataRank · unranked

43 citations

Nandan Haloi, Rebecca J. Ulrich, Mary Elizabeth Metcalf, Po‐Chao Wen, William W. Metcalf +4 more

A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain

ACS Chemical Biology(2023)10.1021/acschembio.3c00092

N/A

0.406DataRank · unranked

14 citations

Sadhan Jana, Kewen Peng, Shamar D. Wallace, Saket R. Bagde, Bryon Drown +5 more

Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy

Neoplasia(2021)10.1016/j.neo.2021.06.008

N/A

0.373DataRank · unranked

11 citations

Matthew W. Boudreau, Kim A. Selting, Lindsay E. Chatkewitz, Jonathan Samuelson, Joshua M. Francis +5 more

The combination of PAC-1 and entrectinib for the treatment of metastatic uveal melanoma

Melanoma Research(2023)10.1097/cmr.0000000000000927

N/A

0.342DataRank · unranked

8 citations

Emily J. Tonogai, Claire P. Schane, Min Xi, James H. Fischer, Jayanthi Vijayakumar +6 more

A catalytic process enables efficient and programmable access to precisely altered indole alkaloid scaffolds

Nature Chemistry(2024)10.1038/s41557-024-01455-7

N/A

0.269DataRank · unranked

5 citations

Xinghan Li, Binh Khanh, Emily J. Tonogai, Amanda Smith, Paul J. Hergenrother +3 more

Investigation of gating in outer membrane porins provides new perspectives on antibiotic resistance mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.09.459668

N/A

0DataRank · unranked

4 citations

Nandan Haloi, Rebecca J. Ulrich, Mary Elizabeth Metcalf, Po‐Chao Wen, William W. Metcalf +4 more

Rationalizing generation of broad spectrum antibiotics with the addition of a primary amine

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.10.455597

N/A

0DataRank · unranked

0 citations

Archit Vasan, Emily J. Geddes, Arjun Prasanna, Po‐Chao Wen, William W. Metcalf +3 more

Porin-independent accumulation in Pseudomonas enables antibiotic discovery

Nature(2023)10.1038/s41586-023-06760-8

N/A

0DataRank · unranked

59 citations

Morgan K. Gugger, Alfredo García, Martin Garcia Chavez, Myung‐Ryul Lee, Sarah J. Perlmutter +4 more

Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy–Induced Necrosis

Cancer Research(2023)10.1158/0008-5472.can-23-0157

N/A

0DataRank · unranked

29 citations

Rachel Yang, Darjan Duraki, Junyao Zhu, Ji Eun Kim, Musarrat Jabeen +9 more

Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0222

N/A

0DataRank · unranked

18 citations

Alok Ranjan, Vasantha Kumar M.V., Bogos Agianian, Martin Garcia Chavez, Vignesh Vudatha +14 more

Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2022-006509

N/A

0DataRank · unranked

12 citations

Preeti Sharma, Claire P. Schane, Amber N Lewis, Edward F. Valdez, Venkata V.V.R. Marada +11 more

Phase I dose-escalation study of procaspase-activating compound-1 in combination with temozolomide in patients with recurrent high-grade astrocytomas

Neuro-Oncology Advances(2023)10.1093/noajnl/vdad087

N/A

0DataRank · unranked

7 citations

M. Kelly Nicholas, Richard A. Peterson, Stefania Maraka, Li Liu, James H. Fischer +10 more

Isopentyl-Deoxynboquinone Induces Mitochondrial Dysfunction and G2/M Phase Cell Cycle Arrest to Selectively Kill NQO1 -Positive Pancreatic Cancer Cells

Antioxidants and Redox Signaling(2023)10.1089/ars.2022.0224

N/A

0DataRank · unranked

6 citations

Yingchun Liu, Soumya Tumbath, Matthew W. Boudreau, Lindsay E. Chatkewitz, Jiangwei Wang +8 more

Data from Discovery and Canine Preclinical Assessment of a Nontoxic Procaspase-3–Activating Compound

(2023)10.1158/0008-5472.c.6500739

N/A

0DataRank · unranked

0 citations

Danny Hsu, Chris J. Novotny, Diana C. West, Dewey Kim, Joanna Schmit +4 more

Re-education of myeloid immune cells to reduce regulatory T cell expansion and impede breast cancer progression

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.14.553229

N/A

0DataRank · unranked

0 citations

Sayyed Hamed Shahoei, Samuel T. Albright, Yu Wang, Amanda Smith, Rachel Farmer +25 more

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

Scientific Reports(2024)10.1038/s41598-024-64868-x

N/A

0DataRank · unranked

15 citations

Daniel S. D. Larsson, Ravi Kiran Koripella, Brett N. Cain, Martin Garcia Chavez, Paul J. Hergenrother +3 more

Using permeation guidelines to design new antibiotics—A PASsagE into Pseudomonas aeruginosa

Clinical and Translational Medicine(2024)10.1002/ctm2.1600

N/A

0DataRank · unranked

14 citations

Paul J. Hergenrother, Brett N. Cain

Development of NR0B2 as a therapeutic target for the re-education of tumor associated myeloid cells

Cancer Letters(2024)10.1016/j.canlet.2024.217086

N/A

0DataRank · unranked

13 citations

Samuel T Albright, Amanda Smith, Rachel Farmer, Sayyed Hamed Shahoei, Yu Wang +25 more

Precise Readout of MEK1 Proteoforms upon MAPK Pathway Modulation by Individual Ion Mass Spectrometry

Analytical Chemistry(2024)10.1021/acs.analchem.3c04758

N/A

0DataRank · unranked

11 citations

Raveena Gupta, John P. McGee, Michael A. R. Hollas, Paul J. Hergenrother, Jared O. Kafader +2 more

Raptinal: a powerful tool for rapid induction of apoptotic cell death

Cell Death Discovery(2024)10.1038/s41420-024-02120-1

N/A

0DataRank · unranked

9 citations

Paul J. Hergenrother, Amanda Smith

NR0B2 re-educates myeloid immune cells to reduce regulatory T cell expansion and progression of breast and other solid tumors

Cancer Letters(2024)10.1016/j.canlet.2024.217042

N/A

0DataRank · unranked

7 citations

Sayyed Hamed Shahoei, Yu Wang, Élise Jacquin, Erin Weisser, Rafael O. Bautista +25 more

Capturing cell morphology dynamics with high temporal resolution using single-shot quantitative phase gradient imaging

Journal of Biomedical Optics(2024)10.1117/1.jbo.29.s2.s22712

N/A

0DataRank · unranked

6 citations

Minsung Kwon, Revathi Manoharaan, Melika Haji Mohammadi, Ashok Zachariah Samuel, Michael P. Mulligan +3 more

Single Dose of a Small Molecule Leads to Complete Regressions of Large Breast Tumors in Mice

ACS Central Science(2025)10.1021/acscentsci.4c01628

N/A

0DataRank · unranked

5 citations

Matthew W. Boudreau, Brooke Bouwens, Yoongyeong Lee, Hunter W. Carrell, Junyao Zhu +6 more

A necrosis inducer promotes an immunogenic response and destroys ovarian cancers in mouse xenografts and patient ascites organoids

Cancer Letters(2025)10.1016/j.canlet.2025.217738

N/A

0DataRank · unranked

5 citations

Musarrat Jabeen, Chengjian Mao, Lawrence Wang, Santanu Ghosh, Xinyi Dai +7 more

PAC-1 Synergizes with Sunitinib to Enhance Cell Death in Pancreatic Neuroendocrine Tumors

ACS Pharmacology & Translational Science(2025)10.1021/acsptsci.5c00052

N/A

0DataRank · unranked

1 citations

Myung‐Ryul Lee, Timothy M. Fan, Paul J. Hergenrother, Hyang Yeon Lee

Comparative oncology in action: vignettes on small molecule development

Veterinary oncology.(2025)10.1186/s44356-025-00022-7

N/A

0DataRank · unranked

1 citations

Christina Mazcko, Cheryl A. London, Paul J. Hergenrother, Timothy M. Fan, Amy K. LeBlanc

Re-engineering natural products to engage new biological targets

Natural Product Reports(2020)10.1039/d0np00059k

N/A

0DataRank · unranked

67 citations

Paul J. Hergenrother, Stephen E. Motika

Multicellular model of temozolomide resistance in glioblastoma reveals phenotypic shifts in drug response and migratory potential

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.08.663674

N/A

0DataRank · unranked

3 citations

Ela K. Eames, Sydney A. McKee, Paul J. Hergenrother, Rebecca B. Riggins, Brendan A.C. Harley +1 more

A Noncompetitive Small Molecule Inhibitor of Estrogen-regulated Gene Expression and Breast Cancer Cell Growth That Enhances Proteasome-dependent Degradation of Estrogen Receptor α

UNC Libraries(2020)10.17615/f1f8-1d34

N/A

0DataRank · unranked

0 citations

Steven K. Nordeen, Paul J. Hergenrother, Elizabeth M. Wilson, Nicole M. Kretzer, Rachel Schiff +5 more

A New Small Molecule Inhibitor of Estrogen Receptor α Binding to Estrogen Response Elements Blocks Estrogen-dependent Growth of Cancer Cells

UNC Libraries(2020)10.17615/hbq2-ya47

N/A

0DataRank · unranked

0 citations

Milu T. Cherian, Elizabeth M. Wilson, Paul J. Hergenrother, Steven K. Nordeen, Jingwei Cheng +8 more

Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges

Cancer Discovery(2021)10.1158/2159-8290.cd-20-0936

N/A

0DataRank · unranked

78 citations

Jenna K. Minami, Arthur Huang, Siavash R. Dehkordi, Shirley H. Lomeli, Jens Luebeck +26 more

A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice

Science Translational Medicine(2021)10.1126/scitranslmed.abf1383

N/A

0DataRank · unranked

35 citations

Darjan Duraki, Lawrence Wang, Chengjian Mao, Ji Eun Kim, Madeline Henn +15 more

Rationalizing the generation of broad spectrum antibiotics with the addition of a positive charge

Chemical Science(2021)10.1039/d1sc04445a

N/A

0DataRank · unranked

30 citations

Archit Vasan, Emily J. Geddes, Arjun Prasanna, Po‐Chao Wen, William W. Metcalf +3 more

Evaluation of a procaspase-3 activator with hydroxyurea or temozolomide against high-grade meningioma in cell culture and canine cancer patients

Neuro-Oncology(2021)10.1093/neuonc/noab161

N/A

0DataRank · unranked

8 citations

Shan Huang, Rachel C. Botham, Matthew R. Berry, Stephen Joslyn, Gregory B. Daniel +10 more