Anna Marie Pyle

Also affiliated with Yale University, Institut thématique Génétique, génomique et bioinformatique

Biochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.802Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The In Vivo and In Vitro Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures

Journal of Virology(2022)10.1128/jvi.01946-21

Top 25%

0.802DataRank

Top 25%24 citations

Rebecca L. Adams, Brett D. Lindenbach, Anna Marie Pyle, Han Wan

Papers

Driven by 39 papers — median percentile 75. Top paper: “The In Vivo and In Vitro Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures”.

The In Vivo and In Vitro Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures

Journal of Virology(2022)10.1128/jvi.01946-21

Top 25%

0.802DataRank

Top 25%24 citations

Rebecca L. Adams, Brett D. Lindenbach, Anna Marie Pyle, Han Wan

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.06.081695

N/A

0.635DataRank · unranked

68 citations

Mia Madel Alfajaro, Victor Gasque, Victoria Habet, Jin Wei, Renata B. Filler +16 more

The West Nile virus genome harbors essential riboregulatory elements with conserved and host-specific functional roles

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2312080121

N/A

0.570DataRank · unranked

18 citations

Lucille H. Tsao, Doug E. Brackney, Anna Marie Pyle, Nicholas C. Huston

Systematic detection of tertiary structural modules in large RNAs and RNP interfaces by Tb-seq

Nature Communications(2023)10.1038/s41467-023-38623-1

N/A

0.530DataRank · unranked

11 citations

Alec N. Sexton, Madison S. Strine, Craig B. Wilen, Matthew D. Simon, Anna Marie Pyle +1 more

SARS-CoV-2-related bat viruses evade human intrinsic immunity but lack efficient transmission capacity

Nature Microbiology(2024)10.1038/s41564-024-01765-z

N/A

0.373DataRank · unranked

11 citations

Mia Madel Alfajaro, Renata B. Filler, Miyu Moriyama, Emma L. Keeler, Zara E. Ranglin +21 more

Covalent Polymer‐RNA Conjugates for Potent Activation of the RIG‐I Pathway

Advanced Healthcare Materials(2024)10.1002/adhm.202303815

N/A

0.208DataRank · unranked

3 citations

Lucinda E. Pastora, Blaise R. Kimmel, Hayden M. Pagendarm, Alexander J. Kwiatkowski, Payton T. Stone +6 more

The molecular mechanism of RIG‐I activation and signaling

Immunological Reviews(2021)10.1111/imr.13022

N/A

0DataRank · unranked

243 citations

Wenshuai Wang, Drew Galls, Rong Guo, Ling Xu, Anna Marie Pyle +1 more

Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.167227

N/A

0DataRank · unranked

21 citations

Amy D. Gelinas, Melissa Linehan, Akiko Iwasaki, Wenshuai Wang, Nebojša Janjić +2 more

De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: A case report

medRxiv(2021)10.1101/2021.11.08.21266069

N/A

0DataRank · unranked

9 citations

Jon Klein, Alexander J. Robertson, Mario A. Peña-Hernández, Michelle J. Lin, Pavitra Roychoudhury +18 more

De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report

Nature Communications(2022)10.1038/s41467-022-29104-y

N/A

0DataRank · unranked

312 citations

Jon Klein, Alexander J. Robertson, Mario A. Peña-Hernández, Michelle J. Lin, Pavitra Roychoudhury +18 more

The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands

Molecular Cell(2022)10.1016/j.molcel.2022.09.029

N/A

0DataRank · unranked

59 citations

Anna Marie Pyle, Wenshuai Wang

rMSA: A Sequence Search and Alignment Algorithm to Improve RNA Structure Modeling

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167904

N/A

0DataRank · unranked

56 citations

Yang Zhang, Anna Marie Pyle, Chengxin Zhang

A rapid RIG-I signaling relay mediates efficient antiviral response

Molecular Cell(2022)10.1016/j.molcel.2022.11.018

N/A

0DataRank · unranked

48 citations

Drew Galls, Benjamin Götte, Wenshuai Wang, Anna Marie Pyle, Daniel Thoresen

Structures of a mobile intron retroelement poised to attack its structured DNA target

Science(2022)10.1126/science.abq2844

N/A

0DataRank · unranked

31 citations

Ling Xu, Pengxin Chai, Junhui Peng, Swapnil C. Devarkar, Anna Marie Pyle +1 more

Direct tracking of reverse-transcriptase speed and template sensitivity: implications for sequencing and analysis of long RNA molecules

Nucleic Acids Research(2022)10.1093/nar/gkac518

N/A

0DataRank · unranked

18 citations

Sara Olson, Shivali Patel, Brenton R. Graveley, Anna Marie Pyle, Litao Guo

Author Correction: Visualizing group II intron dynamics between the first and second steps of splicing

Nature Communications(2022)10.1038/s41467-021-27699-2

N/A

0DataRank · unranked

498 citations

Isabel Chillón, Vito Genna, Pietro Vidossich, Srinivas Somarowthu, Anna Marie Pyle +3 more

Structural insights into intron catalysis and dynamics during splicing

Nature(2023)10.1038/s41586-023-06746-6

N/A

0DataRank · unranked

39 citations

Tianshuo Liu, Kevin Chung, Anna Marie Pyle, Ling Xu

The SMN complex drives structural changes in human snRNAs to enable snRNP assembly

Nature Communications(2023)10.1038/s41467-023-42324-0

N/A

0DataRank · unranked

23 citations

Adriana Roithová, Nenad Radivojević, Michal Sýkora, Archana Bairavasundaram Prusty, Nicholas C. Huston +5 more

The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization

Nature Communications(2023)10.1038/s41467-023-42982-0

N/A

0DataRank · unranked

15 citations

Benjamin Götte, Rong Guo, Anna Marie Pyle, Wenshuai Wang

End-to-end RT-PCR of long RNA and highly structured RNA

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.07.002

N/A

0DataRank · unranked

2 citations

Anna Marie Pyle, Litao Guo

A protocol for capturing RNA-sensing innate immune receptors in multiple conformations by single-particle cryo-EM

STAR Protocols(2023)10.1016/j.xpro.2023.102166

N/A

0DataRank · unranked

1 citations

Olga S. Fedorova, Anna Marie Pyle, Wenshuai Wang

Mechanism of Action of KL-50, a Novel Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers

ChemRxiv(2023)10.26434/chemrxiv-2023-zwj94

N/A

0DataRank · unranked

1 citations

Anna Lo, Olga Fedorova, James L. Elia, Susan Gueble, Kingson Lin +15 more

A compact regulatory RNA element in mouse Hsp70 mRNA

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.22.529618

N/A

0DataRank · unranked

0 citations

Fei Liu, Maria Vera Ugalde, Anna Marie Pyle, Wenshuai Wang

RT-based Sanger sequencing of RNAs containing complex RNA repetitive elements

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.07.003

N/A

0DataRank · unranked

0 citations

Anna Marie Pyle, Litao Guo

Nanoparticle Retinoic Acid-Inducible Gene I Agonist for Cancer Immunotherapy

ACS Nano(2024)10.1021/acsnano.3c06225

N/A

0DataRank · unranked

24 citations

Mohamed Wehbe, Lucinda E. Pastora, Jinming Yang, Blaise R. Kimmel, Kyle M. Garland +11 more

Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers

Journal of the American Chemical Society(2024)10.1021/jacs.3c06483

N/A

0DataRank · unranked

7 citations

Anna Lo, Olga Fedorova, James L. Elia, Susan E. Gueble, Kingson Lin +13 more

A compact regulatory RNA element in mouse Hsp70 mRNA

NAR Molecular Medicine(2024)10.1093/narmme/ugae002

N/A

0DataRank · unranked

5 citations

Fei Liu, María Vera, Anna Marie Pyle, Wenshuai Wang

Characterization and implementation of the MarathonRT template-switching reaction to expand the capabilities of RNA-seq

RNA(2024)10.1261/rna.080032.124

N/A

0DataRank · unranked

4 citations

Anastasiya Grinko, Sara Olson, Alexander M. Leipold, Brenton R. Graveley, Antoine‐Emmanuel Saliba +2 more

Fabrication of RIG-I-Activating Nanoparticles for Intratumoral Immunotherapy via Flash Nanoprecipitation

Molecular Pharmaceutics(2025)10.1021/acs.molpharmaceut.5c00125

N/A

0DataRank · unranked

7 citations

Alexander J. Kwiatkowski, Eric W. Roth, Olga Fedorova, Anna Marie Pyle, John T. Wilson +1 more

Novel Quinazoline Derivatives Inhibit Splicing of Fungal Group II Introns

ACS Chemical Biology(2025)10.1021/acschembio.4c00631

N/A

0DataRank · unranked

4 citations

M.‐Z. LUO, G. Erik Jagdmann, Michael C. Van Zandt, Luke J. Sisto, Anna Marie Pyle +1 more

Molecular insights into de novo small-molecule recognition by an intron RNA structure

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2502425122

N/A

0DataRank · unranked

4 citations

Ling Xu, Kevin Chung, Luke J. Sisto, Jimin Hwang, Chengxin Zhang +3 more

Single-cell RNA-seq using UltraMarathonRT expands the known transcriptome

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.06.680646

N/A

0DataRank · unranked

0 citations

Anastasiya Grinko, Litao Guo, Alexander M. Leipold, Teresa Rummel, Florian Erhard +3 more

Sequencing and Structure Probing of Long RNAs Using MarathonRT: A Next-Generation Reverse Transcriptase

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.03.022

N/A

0DataRank · unranked

81 citations

Rebecca L. Adams, Han Wan, Nicholas C. Huston, Olga Potapova, Sara Olson +5 more

A ribosome-bound pseudoknot in the HCV coding region stimulates viral growth by tuning viral translation

Cell Reports(2025)10.1016/j.celrep.2025.116739

N/A

0DataRank · unranked

0 citations

Harim Jang, Ling Xu, Kyrillos Abdallah, Wendy V. Gilbert, Anna Marie Pyle +1 more

Visualizing group II intron dynamics between the first and second steps of splicing

Nature Communications(2020)10.1038/s41467-020-16741-4

N/A

0DataRank · unranked

70 citations

Isabel Chillón, Vito Genna, Pietro Vidossich, Srinivas Somarowthu, Anna Marie Pyle +3 more

The Global and Local Distribution of RNA Structure throughout the SARS-CoV-2 Genome

Journal of Virology(2020)10.1128/jvi.02190-20

N/A

0DataRank · unranked

68 citations

Gandhar Mahadeshwar, Han Wan, Nicholas C. Huston, Anna Marie Pyle, Rafael de Cesaris Araujo Tavares

Comprehensive in-vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.10.197079

N/A

0DataRank · unranked

59 citations

Han Wan, Rafael de Cesaris Araujo Tavares, Craig B. Wilen, Anna Marie Pyle, Nicholas C. Huston

Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

Molecular Cell(2021)10.1016/j.molcel.2020.12.041

N/A

0DataRank · unranked

355 citations

Han Wan, Madison S. Strine, Rafael de Cesaris Araujo Tavares, Craig B. Wilen, Anna Marie Pyle +1 more

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes

PLoS Biology(2021)10.1371/journal.pbio.3001143

N/A

0DataRank · unranked

282 citations

Mia Madel Alfajaro, Victor Gasque, Nicholas C. Huston, Han Wan, Klara Szigeti‐Buck +22 more

Anna Marie Pyle

Indexed papers

Top data-sharing exemplar

Papers