Mario J. Borgnia

Also affiliated with National Institute of Environmental Health Sciences

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyNeuroscienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 63 papers. Top paper: “The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage”.

The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1916555117

N/A

1.4DataRank · unranked

36 citations

Benjamin S. Roberts, Fengbin Wang, Joshua D. Strauss, Mario J. Borgnia, Edward H. Egelman +2 more

Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export

Immunity(2025)10.1016/j.immuni.2024.12.002

N/A

0.632DataRank · unranked

21 citations

Joshua A. Boyer, Stephanie Cambier, Jordyn J. VanPortfliet, Xuewu Sui, Gaya P. Yadav +7 more

Spontaneous base flipping helps drive Nsp15’s preferences in double stranded RNA substrates

Nature Communications(2025)10.1038/s41467-024-55682-0

N/A

0.402DataRank · unranked

7 citations

Kevin John Butay, J.M. Krahn, Isha M. Wilson, Scott A. Gabel, Eugene F. DeRose +7 more

Coordinated DNA polymerization by Polγ and the region of LonP1 regulated proteolysis

Nucleic Acids Research(2024)10.1093/nar/gkae539

N/A

0.394DataRank · unranked

8 citations

Asia J Brannon, J.M. Krahn, Jonathan Bouvette, Jason G. Williams, Mario J. Borgnia +2 more

Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase γ

Nucleic Acids Research(2024)10.1093/nar/gkae670

N/A

0.378DataRank · unranked

7 citations

Jonathan Bouvette, Lars C. Pedersen, Shruti Somai, Robert Dutcher, Mario J. Borgnia +2 more

A higher order PUF complex is central to regulation of C. elegans germline stem cells

Nature Communications(2025)10.1038/s41467-024-55526-x

N/A

0.104DataRank · unranked

1 citations

Sarah L. Crittenden, Brian H. Carrick, Lucas Dillard, Stephany J. Costa Dos Santos, Venkata P. Dandey +10 more

Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.11.244863

N/A

0DataRank · unranked

8 citations

Meredith N. Frazier, Lucas Dillard, Jason G. Williams, Seda Kocaman, J.M. Krahn +11 more

Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.30.178921

N/A

0DataRank · unranked

4 citations

Robert Meyerhoff, RJ Edwards, Hui Li, Nathan I. Nicely, Rory Henderson +38 more

Heat-dependent opening of TRPV1 in the presence of capsaicin

Nature Structural & Molecular Biology(2021)10.1038/s41594-021-00616-3

N/A

0DataRank · unranked

237 citations

Feng Zhang, Yang Suo, Jonathan Bouvette, Mario J. Borgnia, Seok‐Yong Lee +1 more

Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics

Nature Communications(2021)10.1038/s41467-020-20608-z

N/A

0DataRank · unranked

139 citations

Meredith N. Frazier, Lucas Dillard, Jason G. Williams, Seda Kocaman, J.M. Krahn +11 more

Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography

Nature Communications(2021)10.1038/s41467-021-22251-8

N/A

0DataRank · unranked

102 citations

Hsuan-Fu Liu, Xiaochen Du, Ye Zhou, Andrew P. Sikkema, Juliana da Fonseca Rezende e Mello +6 more

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

Cell(2021)10.1016/j.cell.2021.04.042

N/A

0DataRank · unranked

92 citations

Robert Meyerhoff, Robert J. Edwards, Hui Li, Kartik Manne, Nathan I. Nicely +47 more

Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U

Nucleic Acids Research(2021)10.1093/nar/gkab719

N/A

0DataRank · unranked

80 citations

Lucas Dillard, J.M. Krahn, L. Perera, Jason G. Williams, Isha M. Wilson +6 more

Tau induces formation of α-synuclein filaments with distinct molecular conformations

Biochemical and Biophysical Research Communications(2021)10.1016/j.bbrc.2021.03.091

N/A

0DataRank · unranked

35 citations

Anvesh K. R. Dasari, Urmi Sengupta, Dianne W. Taylor, Nadia Daneshparvar, Fatemeh Abbasi Yeganeh +8 more

Camel nanobodies broadly neutralize SARS-CoV-2 variants

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.27.465996

N/A

0DataRank · unranked

12 citations

Hyung Joon Kwon, Raúl E. Cachau, Catherine Z. Chen, Kevin John Butay, Zhijian Duan +13 more

Distinct cryo-EM Structure of α-synuclein Filaments derived by Tau

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2020.12.31.424989

N/A

0DataRank · unranked

8 citations

Anvesh K. R. Dasari, Urmi Sengupta, Dianne W. Taylor, Nadia Daneshparvar, Fatemeh Abbasi Yeganeh +8 more

Characterization of SARS2 Nsp15 Nuclease Activity Reveals it’s Mad About U

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.01.446181

N/A

0DataRank · unranked

5 citations

Lucas Dillard, J.M. Krahn, L. Perera, Jason G. Williams, Isha M. Wilson +6 more

Redox sensitive E2 Rad6 controls cellular response to oxidative stress via K63 ubiquitination of ribosomes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.22.439970

N/A

0DataRank · unranked

3 citations

Lana Harley, Blanche K. Cizubu, Ye Zhou, Joshua Pajak, Nathan Snyder +6 more

A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.22.465476

N/A

0DataRank · unranked

1 citations

Juliana da Fonseca Rezende e Mello, Bryan D. Fleming, Alex Renn, Catherine Z. Chen, Xin Hu +26 more

Untwisted α-synuclein Filaments formed in the Presence of Lipid Vesicles

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.19.464986

N/A

0DataRank · unranked

0 citations

Lucas Dillard, Alimohammad Hojjatian, Urmi Sengupta, Rakez Kayed, Kenneth A. Taylor +3 more

Structural basis of NPR1 in activating plant immunity

Nature(2022)10.1038/s41586-022-04699-w

N/A

0DataRank · unranked

201 citations

Raul Zavaliev, Qinglin Wu, Ye Zhou, Jie Cheng, Lucas Dillard +9 more

Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2

Science(2022)10.1126/science.add1268

N/A

0DataRank · unranked

104 citations

Feng Zhang, Shasha Feng, Kevin John Butay, Mario J. Borgnia, Wonpil Im +2 more

Automated systematic evaluation of cryo-EM specimens with SmartScope

eLife(2022)10.7554/elife.80047

N/A

0DataRank · unranked

57 citations

Qinwen Huang, Amanda A. Riccio, William C. Copeland, Alberto Bartesaghi, Mario J. Borgnia +1 more

Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease

Nucleic Acids Research(2022)10.1093/nar/gkac589

N/A

0DataRank · unranked

53 citations

Isha M. Wilson, J.M. Krahn, Kevin John Butay, Lucas Dillard, Mario J. Borgnia +2 more

Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria

Nature Communications(2022)10.1038/s41467-022-31573-0

N/A

0DataRank · unranked

41 citations

Jared V. Peck, Raul Salinas, B.J. Dopkins, Nicholas Lent, Viet D. Nguyen +4 more

Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes

Cell Reports(2022)10.1016/j.celrep.2022.110860

N/A

0DataRank · unranked

39 citations

Blanche K. Cizubu, Lana Harley, Ye Zhou, Joshua Pajak, Nathan Snyder +6 more

Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2201433119

N/A

0DataRank · unranked

37 citations

Hyung Joon Kwon, Raúl E. Cachau, Catherine Z. Chen, Kevin John Butay, Zhijian Duan +13 more

Structural insight and characterization of human Twinkle helicase in mitochondrial disease

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2207459119

N/A

0DataRank · unranked

23 citations

Jonathan Bouvette, L. Perera, Matthew J. Longley, J.M. Krahn, Jason G. Williams +4 more

A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike

PLoS ONE(2022)10.1371/journal.pone.0272364

N/A

0DataRank · unranked

18 citations

Juliana da Fonseca Rezende e Mello, Bryan D. Fleming, Alex Renn, Catherine Z. Chen, Xin Hu +27 more

Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold

Nature Communications(2022)10.1038/s41467-022-34610-0

N/A

0DataRank · unranked

18 citations

Fleur L. Chapus, Elizabeth Viverette, Jason G. Williams, Leesa J. Deterding, J.M. Krahn +5 more

Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles

Biochemistry(2022)10.1021/acs.biochem.2c00283

N/A

0DataRank · unranked

16 citations

Lucas Dillard, Sujung Yi, Elizabeth Viverette, Alimohammad Hojjatian, Urmi Sengupta +5 more

High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102073

N/A

0DataRank · unranked

7 citations

Andrew P. Sikkema, Allen L. Hsu, James C. Horng, Traci M. Tanaka Hall, Mario J. Borgnia +2 more

Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2123092119

N/A

0DataRank · unranked

7 citations

Deepa Singh, Cassandra Smith, Allen L. Hsu, Lucas Dillard, J.M. Krahn +5 more

Method for the structural analysis of Twinkle mitochondrial DNA helicase by cryo-EM

Methods(2022)10.1016/j.ymeth.2022.06.012

N/A

0DataRank · unranked

3 citations

Jonathan Bouvette, Matthew J. Longley, J.M. Krahn, Mario J. Borgnia, William C. Copeland +1 more

Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly

PNAS Nexus(2022)10.1093/pnasnexus/pgac118

N/A

0DataRank · unranked

2 citations

Yu‐Hua Lo, J.M. Krahn, Mack Sobhany, Venkata P. Dandey, Matthew Petrovich +6 more

Structural and functional landscape of α-synuclein fibril conformations amplified from cerebrospinal fluid

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.13.499896

N/A

0DataRank · unranked

8 citations

Ye Zhou, Enquan Xu, Elizabeth Viverette, Lucas Dillard, Yuan Yuan +7 more

Flipped Over U: Structural Basis for dsRNA Cleavage by the SARS-CoV-2 Endoribonuclease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.02.480688

N/A

0DataRank · unranked

6 citations

Isha M. Wilson, J.M. Krahn, Kevin John Butay, Lucas Dillard, Mario J. Borgnia +2 more

Automated systematic evaluation of cryo-EM specimens with SmartScope

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.05.490801

N/A

0DataRank · unranked

3 citations

Qinwen Huang, Amanda A. Riccio, William C. Copeland, Alberto Bartesaghi, Mario J. Borgnia +1 more

Structural and functional landscape of α-synuclein fibril conformations amplified from cerebrospinal fluid

Research Square(2022)10.21203/rs.3.rs-1832778/v1

N/A

0DataRank · unranked

2 citations

Ye Zhou, Enquan Xu, Elizabeth Viverette, Lucas Dillard, Yuan Yuan +7 more

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-01017-4

N/A

0DataRank · unranked

64 citations

Nicholas J. Wright, Hugo Guterres, Justin G. Fedor, Kevin John Butay, Mario J. Borgnia +3 more

Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-00991-z

N/A

0DataRank · unranked

31 citations

Kevin John Butay, Zachary D. Stewart, J.M. Krahn, L. Perera, Jason G. Williams +6 more

Structure and dynamics of the Arabidopsis O-fucosyltransferase SPINDLY

Nature Communications(2023)10.1038/s41467-023-37279-1

N/A

0DataRank · unranked

14 citations

Yan Wang, Ye Zhou, Lucas Dillard, Fay‐Wei Li, Carly A. Sciandra +10 more

Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2

Molecular Cell(2023)10.1016/j.molcel.2023.09.024

N/A

0DataRank · unranked

14 citations

Oya Bermek, Venkata P. Dandey, Makayla Wood, Elizabeth Viverette, Jason G. Williams +6 more

Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.15.532610

N/A

0DataRank · unranked

8 citations

Nicholas J. Wright, Hugo Guterres, Justin G. Fedor, Kevin John Butay, Mario J. Borgnia +3 more

Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : a target for novel antifungals

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.14.530545

N/A

0DataRank · unranked

4 citations

Ye Zhou, Allen L. Hsu, Matthew Petrovich, Jennifer L. Tenor, Dena L. Toffaletti +6 more

Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases

Science Advances(2024)10.1126/sciadv.adq3539

N/A

0DataRank · unranked

32 citations

Ye Zhou, Meltem Tatlı, Kevin Burbidge, Enquan Xu, Elizabeth Viverette +17 more

Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : A target for antifungals

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2314087121

N/A

0DataRank · unranked

16 citations

Ye Zhou, Allen L. Hsu, Matthew Petrovich, Jennifer L. Tenor, Dena L. Toffaletti +6 more

Antiviral drug recognition and elevator-type transport motions of CNT3

Nature Chemical Biology(2024)10.1038/s41589-024-01559-8

N/A

0DataRank · unranked

10 citations

Feng Zhang, Yang Suo, Lingyang Kong, Ying Yin, Justin G. Fedor +5 more

Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin

ACS Catalysis(2024)10.1021/acscatal.4c00677

N/A

0DataRank · unranked

7 citations

Juno A. Krahn, Elizabeth Viverette, Robert Dutcher, Vijayakanth Pagadala, Mario J. Borgnia +3 more

Characterization of α-synuclein oligomers formed in the presence of lipid vesicles

Biochemistry and Biophysics Reports(2024)10.1016/j.bbrep.2024.101687

N/A

0DataRank · unranked

5 citations

Urmi Sengupta, Elizabeth Viverette, Mario J. Borgnia, Rakez Kayed, Kwang Hun Lim +1 more

A higher order PUF complex is central to regulation of C. elegans germline stem cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.14.599074

N/A

0DataRank · unranked

1 citations

Sarah L. Crittenden, Brian H. Carrick, Lucas Dillard, Stephany J. Costa Dos Santos, Venkata P. Dandey +10 more

Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against Hemolytic Uremic Syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.21.626268

N/A

0DataRank · unranked

1 citations

Arvind Sharma, María L. Cerutti, Kedar Sharma, Roberto Melero, Romina Pardo +5 more

Molecular basis of neurosteroid and anticonvulsant regulation of TRPM3

Nature Structural & Molecular Biology(2025)10.1038/s41594-024-01463-8

N/A

0DataRank · unranked

25 citations

Cheon-Gyu Park, Shasha Feng, Ziqiang Guan, Hyuk-Joon Lee, Feng Zhang +5 more

Molecular basis of the urate transporter URAT1 inhibition by gout drugs

Nature Communications(2025)10.1038/s41467-025-60480-3

N/A

0DataRank · unranked

12 citations

Justin G. Fedor, Han Zhang, Kalina Tsolova, Xiaoyu Shi, Kedar Sharma +6 more

Structural insights into proteolysis-dependent and -independent suppression of the master regulator DELLA by the gibberellin receptor.

PubMed(2025)10.1073/pnas.2511012122

N/A

0DataRank · unranked

6 citations

Yan Wang, Jianhong Hu, Jeongmoo Park, Karly Forker, Zhong-Lin Zhang +5 more

VitriFlex: An Open-Source, Modular, and Customizable Robotic Platform for Cryo-EM Grid Preparation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.24.666634

N/A

0DataRank · unranked

0 citations

Kedar Sharma, Thomas B. Stanley, Randy K. Bledsoe, Robert M. Petrovich, Mario J. Borgnia +2 more

Controlling the SARS-CoV-2 spike glycoprotein conformation

Nature Structural & Molecular Biology(2020)10.1038/s41594-020-0479-4

N/A

0DataRank · unranked

485 citations

Robert J. Edwards, Katayoun Mansouri, Katarzyna Janowska, Victoria Stalls, S. Gobeil +8 more

Advances in automation for cryo-electron tomography data collection

Current Opinion in Structural Biology(2025)10.1016/j.sbi.2025.103192

N/A

0DataRank · unranked

0 citations

Mario J. Borgnia, Kedar Sharma

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

Nature Communications(2020)10.1038/s41467-019-14196-w

N/A

0DataRank · unranked

59 citations

Maolin Lu, Ye Zhou, Zekun Mu, Robert Parks, Qi Han +13 more

Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein

Nature Structural & Molecular Biology(2020)10.1038/s41594-020-0373-0

N/A

0DataRank · unranked

55 citations

Mario J. Borgnia, Allen L. Hsu, Lothar Esser, Tara Fox, Natalia de Val +2 more

Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2005301117

N/A

0DataRank · unranked

36 citations

Panagiotis L. Kastritis, Shannon E. Dougherty, Jonathan Bouvette, Allen L. Hsu, Laura Burbaum +10 more

Structural Basis for Virulence Activation of Francisella tularensis

Molecular Cell(2020)10.1016/j.molcel.2020.10.035

N/A

0DataRank · unranked

36 citations

Kathryn M. Ramsey, Samantha M. Prezioso, Thomas Tallo, Jamie M. Wandzilak, Allen L. Hsu +6 more

Controlling the SARS-CoV-2 Spike Glycoprotein Conformation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.18.102087

N/A

0DataRank · unranked

65 citations

Robert J. Edwards, Katayoun Mansouri, Katarzyna Janowska, Victoria Stalls, S. Gobeil +7 more