Hans‐Joachim Lehmler

Also affiliated with Iowa Department of Public Health, University of Iowa Health Care

Environmental SciencePharmacology, Toxicology and PharmaceuticsBiochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Updating “Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3′,4,4′,5-Pentachlorobiphenyl (PCB126)” with additional data on exposure to 2,2′,5,5′-tetrachlorobiphenyl (PCB52) or its 4-hydroxy metabolite (4-OH-PCB52)

Data in Brief(2023)10.1016/j.dib.2023.109415

Top 100%

0DataRank

Top 100%0 citations

Michael S. Chimenti, Hans‐Joachim Lehmler, James A. Ankrum, Aloysius J. Klingelhutz, Françoise A. Gourronc

Papers

Driven by 60 papers — median percentile 0. Top paper: “Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice”.

Combined Maternal Exposure to Cypermethrin and Stress Affect Embryonic Brain and Placental Outcomes in Mice

Toxicological Sciences(2020)10.1093/toxsci/kfaa040

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0.574DataRank · unranked

45 citations

Khaled Kayali, Ram Dhakal, Bailey O’Hare, Kai Wang, Hans‐Joachim Lehmler +2 more

Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice

Toxicological Sciences(2020)10.1093/toxsci/kfaa090

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0.561DataRank · unranked

41 citations

Xueshu Li, Hans‐Joachim Lehmler, Dongfang Wang, Haiwei Gu, Julia Yue Cui +1 more

Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment

Environmental Research(2023)10.1016/j.envres.2023.115227

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0.489DataRank · unranked

25 citations

Xueshu Li, Kari Neier, Yihui Zhu, Charles E. Mordaunt, Michele A. La Merrill +6 more

Hydroxylation markedly alters how the polychlorinated biphenyl (PCB) congener, PCB52, affects gene expression in human preadipocytes

Toxicology in Vitro(2023)10.1016/j.tiv.2023.105568

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0.442DataRank · unranked

18 citations

Michael S. Chimenti, Hans‐Joachim Lehmler, James A. Ankrum, Aloysius J. Klingelhutz, Françoise A. Gourronc

Structure–Activity Relationship of Lower Chlorinated Biphenyls and Their Human-Relevant Metabolites for Astrocyte Toxicity

Chemical Research in Toxicology(2023)10.1021/acs.chemrestox.3c00095

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0.434DataRank · unranked

17 citations

Laura E. Dean, Andrés Martínez, Ronald B. Tjalkens, Hans‐Joachim Lehmler, Jonathan A. Doorn +1 more

Disposition and metabolomic effects of 2,2′,5,5′-tetrachlorobiphenyl in female rats following intraperitoneal exposure

Environmental Toxicology and Pharmacology(2023)10.1016/j.etap.2023.104245

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0.406DataRank · unranked

14 citations

Xueshu Li, Zhang Chunyun, Kendra Lee, Casey Pulliam, Brianna Cagle +5 more

Toxicity Impacts on Human Adipose Mesenchymal Stem/Stromal Cells Acutely Exposed to Aroclor and Non-Aroclor Mixtures of Polychlorinated Biphenyl

Environmental Science & Technology(2023)10.1021/acs.est.2c07281

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0.406DataRank · unranked

14 citations

Jesse N. Liszewski, Michael V. Schrodt, Bhavya Vats, Xueshu Li, Hans‐Joachim Lehmler +3 more

Identification of polychlorinated biphenyls (PCBs) and PCB metabolites associated with changes in the gut microbiome of female mice exposed to an environmental PCB mixture

Journal of Hazardous Materials(2025)10.1016/j.jhazmat.2025.137688

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0.396DataRank · unranked

13 citations

Hui Wang, Xueshu Li, Rachel L. Fitzjerrells, Anthony E. Valenzuela, Kari Neier +5 more

Genetic background in the rat affects endocrine and metabolic outcomes of bisphenol F exposure

Toxicological Sciences(2023)10.1093/toxsci/kfad046

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0.360DataRank · unranked

10 citations

Katie L. Holl, Karen C Clark, John J. Reho, Melinda R. Dwinell, Hans‐Joachim Lehmler +4 more

The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL/6 Mice

Toxicological Sciences(2021)10.1093/toxsci/kfab142

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0.312DataRank · unranked

7 citations

Nicole Cady, Chunyun Zhang, Rachel L. Shrode, Michael L. McCormick, Douglas R. Spitz +5 more

The dichloroacetamide safener benoxacor is enantioselectively metabolized by monkey liver microsomes and cytosol

Environmental Toxicology and Pharmacology(2022)10.1016/j.etap.2022.104008

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0.269DataRank · unranked

5 citations

Jacob Heffelfinger, David M. Cwiertny, Hans‐Joachim Lehmler, Derek Simonsen

Benoxacor is enantioselectively metabolized by microsomes and cytosol from the human liver

Emerging contaminants(2022)10.1016/j.emcon.2022.100198

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0.208DataRank · unranked

3 citations

Jacob Heffelfinger, David M. Cwiertny, Hans‐Joachim Lehmler, Derek Simonsen

Ramping up the Heat: Induction of Systemic and Pulmonary Immune Responses and Metabolic Adaptations in Mice

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.01.667768

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0.112DataRank · unranked

1 citations

Andrea Adamcakova‐Dodd, Hans‐Joachim Lehmler, Laura E. Dean

Quantitative analysis of polychlorinated biphenyls (PCBs) and hydroxylated PCBs

(2021)10.17077/etd.006276

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0DataRank · unranked

0 citations

Keri C. Hornbuckle, Andrés Martínez, Elizabeth A. Stone, Hans‐Joachim Lehmler, Kai Wang +1 more

A systematic review of human biomonitoring studies of 3-phenoxybenzoic acid, a urinary biomarker pyrethroid insecticide exposure, 1997 to 2019

Hygiene and Environmental Health Advances(2022)10.1016/j.heha.2022.100018

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0DataRank · unranked

19 citations

Derek Simonsen, Alana Quintero Garcia, Nafis Md. Irfan, Laura E. Dean, Hui Wang +3 more

Toxicity impacts on human adipose MSCs acutely exposed to Aroclor and non-Aroclor mixtures of PCBs

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.17.516943

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0DataRank · unranked

3 citations

Jesse N. Liszewski, Michael V. Schrodt, Bhavya Vats, Xueshu Li, Hans‐Joachim Lehmler +3 more

Genetic Background in the Rat Impacts Metabolic Outcomes of Post‐wean BPF Exposure

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3968

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0DataRank · unranked

0 citations

Karen C Clark, Katie L. Holl, John J. Reho, Leah C. Solberg Woods, Hans‐Joachim Lehmler +3 more

Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment

medRxiv(2022)10.1101/2022.11.13.22282272

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0DataRank · unranked

0 citations

Xueshu Li, Kari Neier, Yihui Zhu, Charles E. Mordaunt, Michele A. La Merrill +6 more

Low-dose glyphosate exposure alters gut microbiota composition and modulates gut homeostasis

Environmental Toxicology and Pharmacology(2023)10.1016/j.etap.2023.104149

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0DataRank · unranked

63 citations

Nicole Cady, Sudeep Ghimire, Shailesh K. Shahi, Rachel L. Shrode, Hans‐Joachim Lehmler +2 more

Prevalence of neonicotinoid insecticides in paired private-well tap water and human urine samples in a region of intense agriculture overlying vulnerable aquifers in eastern Iowa

Chemosphere(2023)10.1016/j.chemosphere.2023.137904

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0DataRank · unranked

34 citations

Dana W. Kolpin, Michelle L. Hladik, Hans‐Joachim Lehmler, Shannon M. Meppelink, Matthew C. Poch +10 more

The Power of the Heterogeneous Stock Rat Founder Strains in Modeling Metabolic Disease

Endocrinology(2023)10.1210/endocr/bqad157

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0DataRank · unranked

5 citations

Katie L. Holl, Karen C Clark, John J. Reho, Hans‐Joachim Lehmler, Kai Wang +5 more

Use of a polymeric implant system to assess the neurotoxicity of subacute exposure to 2,2′,5,5′-tetrachlorobiphenyl-4-ol, a human metabolite of PCB 52, in male adolescent rats

Toxicology(2023)10.1016/j.tox.2023.153677

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0DataRank · unranked

8 citations

Amanda J. Bullert, Xueshu Li, Hanna E. Stevens, Aloysius J. Klingelhutz, James A. Ankrum +4 more

Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2′,3,5′,6-Pentachlorobiphenyl (PCB 95) in Wildtype, Cyp2abfgs-Null, and CYP2A6-Humanized Mice

Chemical Research in Toxicology(2023)10.1021/acs.chemrestox.3c00128

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0DataRank · unranked

2 citations

Amanda J. Bullert, Weiguo Han, Weizhu Yang, Qingyu Zhang, Xinxin Ding +2 more

Predicted versus observed activity of PCB mixtures toward the ryanodine receptor

NeuroToxicology(2023)10.1016/j.neuro.2023.12.003

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0DataRank · unranked

2 citations

Xueshu Li, Hans‐Joachim Lehmler, Erika B. Holland, Justin A. Griffin

Rebuttal to Correspondence on “Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples”

Environmental Science & Technology(2023)10.1021/acs.est.3c01659

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0DataRank · unranked

1 citations

Xueshu Li, Kimberly P. Keil, Sunjay Sethi, Weizhu Yang, Rachel F. Marek +5 more

IHC analysis of brain regions from PCB exposed rats v1

(2023)10.17504/protocols.io.kqdg3xbbeg25/v1

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0DataRank · unranked

1 citations

Morgan Linahon, Michael Dailey, Hans‐Joachim Lehmler, Amanda J. Bullert

Updating “Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3′,4,4′,5-Pentachlorobiphenyl (PCB126)” with additional data on exposure to 2,2′,5,5′-tetrachlorobiphenyl (PCB52) or its 4-hydroxy metabolite (4-OH-PCB52)

Data in Brief(2023)10.1016/j.dib.2023.109415

Top 100%

0DataRank

Top 100%0 citations

Michael S. Chimenti, Hans‐Joachim Lehmler, James A. Ankrum, Aloysius J. Klingelhutz, Françoise A. Gourronc

Interactions of Polychlorinated Biphenyls and Their Metabolites with the Brain and Liver Transcriptome of Female Mice

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00367

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0DataRank · unranked

20 citations

Hui Wang, Anthony E. Valenzuela, Kari Neier, Rebecca J. Wilson, Jessie R Badley +5 more

A systematic review of herbicide safener toxicity

Critical Reviews in Toxicology(2024)10.1080/10408444.2024.2391431

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0DataRank · unranked

13 citations

Vanessa Livania, David M. Cwiertny, Riley J. Samuelson, John D. Sivey, Hans‐Joachim Lehmler +1 more

Astrocyte Mitochondria Are a Sensitive Target of PCB52 and its Human-Relevant Metabolites

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00116

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0DataRank · unranked

16 citations

Stefan Strack, Hans‐Joachim Lehmler, Jonathan A. Doorn, Neha Paranjape

Complex roles for sulfation in the toxicities of polychlorinated biphenyls

Critical Reviews in Toxicology(2024)10.1080/10408444.2024.2311270

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0DataRank · unranked

12 citations

Hans‐Joachim Lehmler, Michael W. Duffel

Significant metabolic alterations in mouse dams exposed to an environmental mixture of polychlorinated biphenyls (PCBs) during gestation and lactation: Insights into PCB and metabolite profiles

Environmental Toxicology and Pharmacology(2024)10.1016/j.etap.2024.104567

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0DataRank · unranked

7 citations

Youjun Suh, Rebecca J. Wilson, Pamela J. Lein, Julia Yue Cui, Hans‐Joachim Lehmler +1 more

Upregulation of fatty acid synthesis genes in the livers of adolescent female rats caused by inhalation exposure to PCB52 (2,2′,5,5′-Tetrachlorobiphenyl)

Environmental Toxicology and Pharmacology(2024)10.1016/j.etap.2024.104520

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0DataRank · unranked

6 citations

Amanda J. Bullert, Hui Wang, Michael S. Chimenti, Andrea Adamcakova‐Dodd, Xuefang Jing +7 more

Germ-free status but not subacute polychlorinated biphenyl (PCB) exposure altered hepatic phosphatidylcholine and ether-phosphatidylcholine levels in mice

Toxicology(2024)10.1016/j.tox.2024.153790

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0DataRank · unranked

3 citations

Hui Wang, Amanda J. Bullert, Julia Yue Cui, Kai Wang, Hans‐Joachim Lehmler +1 more

Effects of 28-day nose-only inhalation of PCB52 (2,2′,5,5′-Tetrachlorobiphenyl) on the brain transcriptome

Toxicology(2024)10.1016/j.tox.2024.153965

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0DataRank · unranked

3 citations

Hui Wang, Morgan J Linahon, Michael S. Chimenti, Andrea Adamcakova‐Dodd, Xueshu Li +7 more

Elucidating the Metabolism of Chiral PCB95 in Wildtype and Transgenic Mouse Models with Altered Cytochrome P450 Enzymes Using Intestinal Content Screening

Chemical Research in Toxicology(2024)10.1021/acs.chemrestox.4c00350

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0DataRank · unranked

0 citations

Amanda J. Bullert, Binita Gautam, Weiguo Han, Weizhu Yang, Qingyu Zhang +3 more

Exposure to PCB52 (2,2′,5,5′-tetrachlorobiphenyl) blunts induction of the gene for uncoupling protein 1 (UCP1) in white adipose

Environmental Toxicology and Pharmacology(2024)10.1016/j.etap.2024.104612

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0DataRank · unranked

0 citations

Amanda J. Bullert, Brynn Kyleakin Helm-Kwasny, Andrea Adamcakova‐Dodd, Hui Wang, Xuefang Jing +6 more

A Scoping Review of Neurotoxic and Behavioral Outcomes Following Polychlorinated Biphenyl (PCB) Exposure in Post-Weaned Rodents

International Journal of Molecular Sciences(2025)10.3390/ijms262210829

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0DataRank · unranked

3 citations

Sophia G. Heim, Riley J. Samuelson, Hans‐Joachim Lehmler, Nicole M. Breese

PCB 37 (3,4, 4’-trichlorobiphenyl) increased apoptosis and modulated neuronal morphogenesis in primary rat cortical neuron-glia cocultures in a concentration-, sex-, age-, and CREB-dependent manner

NeuroToxicology(2025)10.1016/j.neuro.2025.08.004

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0DataRank · unranked

1 citations

Peter M. Andrew, Hans‐Joachim Lehmler, Pamela J. Lein, Jessie R Badley

Subacute exposure of male adolescent rats to 2,2′,5,5′-tetrachlorobiphenyl-4-ol via a polymeric implant causes gene expression changes in the brain and metabolomic disruption in serum

Toxicology(2025)10.1016/j.tox.2025.154120

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0DataRank · unranked

1 citations

Amanda J. Bullert, Morgan J Linahon, Michael E. Dailey, Jonathan A. Doorn, Aloysius J. Klingelhutz +3 more

Deconjugation of Polychlorinated Biphenyl Sulfates to Hydroxylated PCBs by Anaerobically Cultured Mouse and Human Gut Microbiota

ChemRxiv(2025)10.26434/chemrxiv-2025-f0lwx

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0DataRank · unranked

0 citations

Joe Jongpyo Lim, Cayen Rong, Hans‐Joachim Lehmler, Julia Yue Cui, Xueshu Li

Single-cell transcriptomics showed that maternal PCB exposure dysregulated ER stress-mediated cell type-specific responses in the liver of female offspring

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.04.657944

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0DataRank · unranked

0 citations

Youjun Suh, Xueshu Li, Rebecca J. Wilson, Hans‐Joachim Lehmler, Pamela J. Lein +2 more

Spatial transcriptomic profiling uncovers the molecular effects of the neurotoxicant polychlorinated biphenyls (PCBs) in the brains of adult mice

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.24.665575

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0DataRank · unranked

0 citations

Nicole M. Breese, Sal Lombardi, Hui Wang, Xueshu Li, Destiny Tiburcio +8 more

Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100174

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0DataRank · unranked

0 citations

Youjun Suh, Xueshu Li, R. Wilson, Hans‐Joachim Lehmler, Pamela J. Lein +2 more

Neurotoxic and Behavioral Outcomes Data Following Polychlorinated Biphenyl (PCB) Exposure in Post-Weaned Rodents

Iowa Research Online (The University of Iowa)(2025)10.25820/data.008102

Top 100%

0DataRank

Top 100%0 citations

Riley J. Samuelson, Heim, Sophia G., Hans‐Joachim Lehmler, Breese, Nicole M

Dataset for 3,3'-Dichlorobiphenyl (PCB 11) Alters the Hepatic Expression of Cytochrome P450 Enzymes in the Liver of Mouse Dams Exposed Orally During Pregnancy and Lactation.

Iowa Research Online (The University of Iowa)(2025)10.25820/data.007803

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0DataRank · unranked

0 citations

Roach, Crystal M, Koester, Nate R., Ahn, Jeonghyeon, Pope, R Marshall, Wilson, Rebecca J. +7 more

Environmental exposure to pyrethroid pesticides in a nationally representative sample of U.S. adults and children: The National Health and Nutrition Examination Survey 2007–2012

Environmental Pollution(2020)10.1016/j.envpol.2020.115489

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0DataRank · unranked

70 citations

Derek Simonsen, Buyun Liu, Wei Bao, Hans‐Joachim Lehmler

Dataset for: The influence of an environmentally relevant polychlorinated biphenyl mixture on the intestinal microbiota in post-weaning mouse dams.

Iowa Research Online (The University of Iowa)(2025)10.25820/data.007799

Top 100%

0DataRank

Top 100%0 citations

Xueshu Li, Shrode, Rachel L, Kai Wang, Ashutosh K. Mangalam, Rachel F. Marek +7 more

Cardiovascular Effects of Polychlorinated Biphenyls and Their Major Metabolites

Environmental Health Perspectives(2020)10.1289/ehp7030

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0DataRank · unranked

62 citations

William D. Klaren, Xueshu Li, Hans‐Joachim Lehmler, Moumita Karmakar, Larry W. Robertson +3 more

Benoxacor is enantioselectively metabolized by rat liver subcellular fractions

Chemico-Biological Interactions(2020)10.1016/j.cbi.2020.109247

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0DataRank · unranked

9 citations

David M. Cwiertny, Hans‐Joachim Lehmler, Derek Simonsen

Enantioselective Partitioning of Polychlorinated Biphenyls in a HepG2 Cell Culture System: Experimental and Modeling Results

ChemRxiv(2020)10.26434/chemrxiv.12126684

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0DataRank · unranked

0 citations

Susanne Flor, Gabriele Ludewig, Hans‐Joachim Lehmler, Chunyun Zhang

Fatty Liver and Impaired Hepatic Metabolism Alters the Congener-Specific Distribution of Polychlorinated Biphenyls (PCBs) in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase

ChemRxiv(2020)10.26434/chemrxiv.12026904.v1

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0DataRank · unranked

0 citations

Chunyun Zhang, Hans‐Joachim Lehmler, Xueshu Li

Fatty Liver and Impaired Hepatic Metabolism Alters the Congener-Specific Distribution of Polychlorinated Biphenyls (PCBs) in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase

ChemRxiv(2020)10.26434/chemrxiv.12026904

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0DataRank · unranked

0 citations

Chunyun Zhang, Hans‐Joachim Lehmler, Xueshu Li

Enantioselective Partitioning of Polychlorinated Biphenyls in a HepG2 Cell Culture System: Experimental and Modeling Results

ChemRxiv(2020)10.26434/chemrxiv.12126684.v1

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0DataRank · unranked

0 citations

Susanne Flor, Gabriele Ludewig, Hans‐Joachim Lehmler, Chunyun Zhang

Systematic review of human biomonitoring studies of ethylenethiourea, a urinary biomarker for exposure to dithiocarbamate fungicides

Environmental Pollution(2021)10.1016/j.envpol.2021.118419

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0DataRank · unranked

32 citations

Xueshu Li, Buyun Liu, Wei Bao, Kai Wang, Hans‐Joachim Lehmler +1 more

Association of Seafood Consumption and Mercury Exposure With Cardiovascular and All-Cause Mortality Among US Adults

JAMA Network Open(2021)10.1001/jamanetworkopen.2021.36367

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0DataRank · unranked

35 citations

Buyun Liu, Shuang Rong, Jing Zhang, Yang Du, Guifeng Xu +5 more

Neonatal Exposure to BPA, BDE-99, and PCB Produces Persistent Changes in Hepatic Transcriptome Associated With Gut Dysbiosis in Adult Mouse Livers

Toxicological Sciences(2021)10.1093/toxsci/kfab104

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0DataRank · unranked

23 citations

Moumita Dutta, Joseph L. Dempsey, Hans‐Joachim Lehmler, James W. MacDonald, Theo K. Bammler +6 more

Environmental Nickel Exposure and Diabetes in a Nationally Representative Sample of US Adults

Exposure and Health(2021)10.1007/s12403-021-00413-9

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0DataRank · unranked

22 citations

Buyun Liu, Hans‐Joachim Lehmler, Linda Snetselaar, Wei Bao, Tyler J. Titcomb

Bisphenol F Exposure in Adolescent Heterogeneous Stock Rats Affects Growth and Adiposity

Toxicological Sciences(2021)10.1093/toxsci/kfab035

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0DataRank · unranked

12 citations

Karen C Clark, Leslie Carrillo-Sáenz, Katie Holl, Miriam Vélez‐Bermúdez, Derek Simonsen +7 more

Human hepatic microsomal sulfatase catalyzes the hydrolysis of polychlorinated biphenyl sulfates: A potential mechanism for retention of hydroxylated PCBs

Environmental Toxicology and Pharmacology(2021)10.1016/j.etap.2021.103757

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0DataRank · unranked

8 citations

Kristopher Tuttle, Hans‐Joachim Lehmler, Larry W. Robertson, Michael W. Duffel

Hans‐Joachim Lehmler

Indexed papers

Top data-sharing exemplar

Papers