Thomas R. Lane

Collaborations Pharmaceuticals (United States)

Computer ScienceMedicinePharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.840Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Quantum Machine Learning for Drug Discovery

ChemRxiv(2020)10.26434/chemrxiv.12781232

Top 48%

0.374DataRank

Top 48%4 citations

Kimberley M. Zorn, Daniel H. Foil, Eni Minerali, Victor O. Gawriljuk, Thomas R. Lane +2 more

Papers

Driven by 30 papers — median percentile 49. Top paper: “Quantum Machine Learning for Drug Discovery”.

Quantum Machine Learning for Drug Discovery

ChemRxiv(2020)10.26434/chemrxiv.12781232

Top 48%

0.374DataRank

Top 48%4 citations

Kimberley M. Zorn, Daniel H. Foil, Eni Minerali, Victor O. Gawriljuk, Thomas R. Lane +2 more

Quantum Machine Learning for Drug Discovery

ChemRxiv(2020)10.26434/chemrxiv.12781232.v1

Top 51%

0.348DataRank

Top 51%6 citations

Kimberley M. Zorn, Daniel H. Foil, Eni Minerali, Victor O. Gawriljuk, Thomas R. Lane +2 more

Machine learning modeling of zebrafish toxicity endpoints after exposure to PROTACs

Toxicological Sciences(2025)10.1093/toxsci/kfaf162

Top 72%

0.118DataRank

Top 72%1 citations

Joshua S. Harris, Thomas R. Lane, Morgan Barnes, Patricia A. Vignaux, Renuka Raman +5 more

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.407361

N/A

0DataRank · unranked

21 citations

Ethan J. Fritch, Thomas R. Lane, Longping V. Tse, Boyd L. Yount, Carol Queiroz Sacramento +19 more

Machine Learning Models Identify Inhibitors of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.16.154765

N/A

0DataRank · unranked

11 citations

Phyo Phyo Kyaw Zin, Daniel H. Foil, Jean Bernatchez, Sungjun Beck, Nathan Beutler +12 more

Tilorone: A Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and Beyond

OSF Preprints (OSF Preprints)(2020)10.31219/osf.io/uxasg

N/A

0DataRank · unranked

5 citations

Thomas R. Lane, Peter B. Madrid, Sean Ekins

Pyronaridine Tetraphosphate Efficacy Against Ebola Virus Infection in Guinea Pig

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.20.001081

N/A

0DataRank · unranked

4 citations

Christopher Massey, Jason E. Comer, Alexander N. Freiberg, Huanying Zhou, Julie Dyall +6 more

Towards the Target: Tilorone, Quinacrine and Pyronaridine Bind to Ebola Virus Glycoprotein

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.26.118182

N/A

0DataRank · unranked

1 citations

Sean Ekins, Thomas R. Lane

Engineering a genetically encoded competitive inhibitor of the KEAP1–NRF2 interaction via structure-based design and phage display

UNC Libraries(2020)10.17615/m47n-hk89

N/A

0DataRank · unranked

0 citations

Gurkan Guntas, Brian Kuhlman, Thomas R. Lane, Ashutosh Tripathy, Kathleen M. Mulvaney +3 more

Strain dependent structural effects and in vivo efficacy of enterovirus-D68 inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.24.474126

N/A

0DataRank · unranked

0 citations

Jianing Fu, Barbara Sherry, E. Bart Tarbet, Brett L. Hurst, Olga Riabova +12 more

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

UNC Libraries(2021)10.17615/5h4x-0k36

N/A

0DataRank · unranked

0 citations

Ethan J. Fritch, Brett L. Hurst, Peter B. Madrid, Carolina Horta Andrade, Thomas R. Lane +20 more

Antiviral Evaluation of Dispirotripiperazines against Hepatitis B Virus

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00974

N/A

0DataRank · unranked

9 citations

John E. Tavis, Qilan Li, Olga Riabova, Natalia Monakhova, Daniel P. Bradley +4 more

N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c02055

N/A

0DataRank · unranked

12 citations

Vadim Makarov, Julie A. Nelson, Rick B. Meeker, Giuseppina Sanna, Olga Riabova +8 more

Efficacy of an isoxazole-3-carboxamide analog of pleconaril in mouse models of Enterovirus-D68 and Coxsackie B5

Antiviral Research(2023)10.1016/j.antiviral.2023.105654

N/A

0DataRank · unranked

9 citations

Jianing Fu, Barbara Sherry, E. Bart Tarbet, Brett L. Hurst, Olga Riabova +15 more

1-Sulfonyl-3-amino-1H-1,2,4-triazoles as Yellow Fever Virus Inhibitors: Synthesis and Structure–Activity Relationship

ACS Omega(2023)10.1021/acsomega.3c06106

N/A

0DataRank · unranked

9 citations

Thomas R. Lane, Thane Jones, Ana C. Puhl, Olga Riabova, Vadim Makarov +2 more

Learning from COVID-19: How drug hunters can prepare for the next pandemic

Drug Discovery Today(2023)10.1016/j.drudis.2023.103723

N/A

0DataRank · unranked

6 citations

Thomas R. Lane, Sean Ekins, Ana C. Puhl

Transporter Inhibition Profile for the Antivirals Tilorone, Quinacrine and Pyronaridine

ACS Omega(2023)10.1021/acsomega.3c00724

N/A

0DataRank · unranked

3 citations

Thomas R. Lane, Ana C. Puhl, Raymond K. Hau, Stephen H. Wright, Nathan J. Cherrington +2 more

The Goldilocks paradigm: comparing classical machine learning, large language models, and few-shot learning for drug discovery applications

Communications Chemistry(2024)10.1038/s42004-024-01220-4

N/A

0DataRank · unranked

29 citations

Patricia A. Vignaux, Mustafa Kemal Ozalp, Jacob Gerlach, Ana C. Puhl, Thomas R. Lane +4 more

Computational drug repositioning identifies niclosamide and tribromsalan as inhibitors of Mycobacterium tuberculosis and Mycobacterium abscessus

Tuberculosis(2024)10.1016/j.tube.2024.102500

N/A

0DataRank · unranked

5 citations

Aaron Goff, David Wild, Ying Ding, Ayano Annis, Randy Kerber +10 more

Repurposing lapatinib as a triple antagonist of chemokine receptors 3, 4, and 5

Molecular Pharmacology(2024)10.1016/j.molpha.2024.100010

N/A

0DataRank · unranked

3 citations

Ana C. Puhl, Patricia A. Vignaux, Keith R. Pennypacker, Sean Ekins, Thomas R. Lane

Near-Term Quantum Classification Algorithms Applied to Antimalarial Drug Discovery

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c00953

N/A

0DataRank · unranked

4 citations

Kelvin Dsouza, Dhruv Ranganath, Joshua S. Harris, Thomas R. Lane, Fabio Urbina +2 more

Discovery of Dual Targeting GSK-3β/HIV-1 Reverse Transcriptase Inhibitors as Neuroprotective Antiviral Agents

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00725

N/A

0DataRank · unranked

4 citations

Renuka Raman, Ana C. Puhl, Thomas R. Lane, Olga Riabova, Elena Kazakova +3 more

Oral Pyronaridine Tetraphosphate Reduces Tissue Presence of Parasites in a Mouse Model of Chagas Disease

ACS Omega(2024)10.1021/acsomega.4c05060

N/A

0DataRank · unranked

1 citations

Thomas R. Lane, Jean Bernatchez, Claudia Magalhaes Calvet Alvarez, Elany Barbosa da Silva, Miriam A. Giardini +2 more

De-risking seizure liability: integrating adverse outcome pathways (AOPs), new approach methodologies (NAMs), and in silico approaches while highlighting knowledge gaps

Toxicological Sciences(2025)10.1093/toxsci/kfaf109

N/A

0DataRank · unranked

6 citations

Agnes L. Karmaus, Mohan Rao, Thomas R. Lane, Joshua D. Harris, Clifford Sachs +6 more

Applications of artificial intelligence in drug discovery for neurological diseases

Neurotherapeutics(2025)10.1016/j.neurot.2025.e00624

N/A

0DataRank · unranked

5 citations

Thomas R. Lane, Sean Ekins

DDI–CYP: Metabolism ensemble models for drug-drug interaction predictions

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100137

N/A

0DataRank · unranked

0 citations

Joshua S. Harris, Thomas R. Lane, Fabio Urbina, Sean Ekins, Jason T. Wong

Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond

Pharmaceutical Research(2020)10.1007/s11095-020-02799-8

N/A

0DataRank · unranked

58 citations

Thomas R. Lane, Peter B. Madrid, Sean Ekins

MegaEye: Applying multiple machine learning approaches to identify oral compounds with ocular bioactivity

Artificial Intelligence in the Life Sciences(2025)10.1016/j.ailsci.2025.100143

N/A

0DataRank · unranked

0 citations

Scott H. Greenwald, Patricia A. Vignaux, Thomas R. Lane, Joshua S. Harris, Mayssa Attar +3 more

Synergistic drug combinations and machine learning for drug repurposing in chordoma

Scientific Reports(2020)10.1038/s41598-020-70026-w

N/A

0DataRank · unranked

43 citations

Tammy M. Havener, Kimberley M. Zorn, Daniel H. Foil, Thomas R. Lane, Stephen J. Capuzzi +5 more

Repurposing Pyramax®, quinacrine and tilorone as treatments for Ebola virus disease

Antiviral Research(2020)10.1016/j.antiviral.2020.104908

N/A

0DataRank · unranked

28 citations

Julie Dyall, Mercer Luke, Caleb Goodin, Daniel H. Foil, Huanying Zhou +6 more

Thomas R. Lane

Indexed papers

Top data-sharing exemplar

Papers