Eric J. Sorscher

Also affiliated with Children's Healthcare of Atlanta

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 35 papers. Top paper: “Evaluation of elexacaftor–tezacaftor–ivacaftor treatment in individuals with cystic fibrosis and CFTRN1303K in the USA: a prospective, multicentre, open-label, single-arm trial”.

Evaluation of elexacaftor–tezacaftor–ivacaftor treatment in individuals with cystic fibrosis and CFTRN1303K in the USA: a prospective, multicentre, open-label, single-arm trial

The Lancet Respiratory Medicine(2024)10.1016/s2213-2600(24)00205-4

N/A

1.1DataRank · unranked

28 citations

Rachel W. Linnemann, Rachel Rich, Ashleigh Streby, Brian Buehler, Eric Hunter +14 more

Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.21.959395

N/A

0.505DataRank · unranked

28 citations

Shingo Suzuki, Mary Lou Beermann, C. Barillà, Ruobing Wang, Carlos Villacorta-Martín +16 more

Improved correction of F508del-CFTR biogenesis with a folding facilitator and an inhibitor of protein ubiquitination

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.128243

N/A

0.406DataRank · unranked

14 citations

R. Aldrin Denny, Disha Joshi, Clare Hill, Mads Larsen, Annette Chiang +5 more

Development of robust antiviral assays using relevant apical-out human airway organoids

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.02.573939

N/A

0.345DataRank · unranked

9 citations

Julia C. LeCher, Eric Parigoris, Noriyuki Shinagawa, Jason Sentosa, Candela Manfredi +11 more

Future Directions in Early Cystic Fibrosis Lung Disease Research: An NHLBI Workshop Report

UNC Libraries(2020)10.17615/5b7f-j030

N/A

0.208DataRank · unranked

3 citations

Frank J. Accurso, Michael R. Knowles, John F. Engelhardt, Bonnie W. Ramsey, Susan V. Lynch +12 more

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

UNC Libraries(2020)10.17615/cqba-1865

N/A

0DataRank · unranked

0 citations

Garry R. Cutting, Zhiwei Cai, Scott A. Houck, Veit, Gudio, David N. Sheppard +13 more

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion

Nature Communications(2021)10.1038/s41467-021-24575-x

N/A

0DataRank · unranked

128 citations

Ming Du, Eric C. Wong, Venkateshwar Mutyam, Yao Li, Jianguo Chen +25 more

Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation

Journal of Cystic Fibrosis(2021)10.1016/j.jcf.2021.06.003

N/A

0DataRank · unranked

53 citations

Michal Irony‐Tur Sinai, Anita Golec, Ofra Barchad-Avitzur, Venkateshwar Mutyam, Li Yao +13 more

The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100598

N/A

0DataRank · unranked

38 citations

Disha Joshi, Luba Simhaev, Kathryn E. Oliver, Hanoch Senderowitz, Marcel van Willigen +5 more

Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

Journal of Chemical Information and Modeling(2021)10.1021/acs.jcim.0c01207

N/A

0DataRank · unranked

16 citations

Netaly Khazanov, Qingxian Zhou, Zhengrong Yang, Chi Chiu Wang, Jeong S. Hong +6 more

Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10kb C-to-T splicing mutation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.14.431123

N/A

0DataRank · unranked

4 citations

Michal Irony‐Tur Sinai, Anita Golec, Ofra Barchad-Avitzur, Venkateshwar Mutyam, Li Yao +11 more

Potential Role of High-Mobility Group Box 1 in Cystic Fibrosis Airway Disease

UNC Libraries(2021)10.17615/33dv-7762

N/A

0DataRank · unranked

0 citations

Alessandra Livraghi, Dualta Mcquaid, Brett D. Noerager, J. Edwin Blalock, Edward Abraham +9 more

Marine Natural Products as Leads against SARS-CoV-2 Infection

Journal of Natural Products(2022)10.1021/acs.jnatprod.2c00015

N/A

0DataRank · unranked

35 citations

Philip R. Tedbury, Anne Marie Sweeney-Jones, Luke Mani, Katy Soapi, Candela Manfredi +4 more

Targeted Gene Insertion for Functional CFTR Restoration in Airway Epithelium

Frontiers in Genome Editing(2022)10.3389/fgeed.2022.847645

N/A

0DataRank · unranked

5 citations

Shingo Suzuki, András Rab, Eric J. Sorscher, Brian R. Davis, C. Barillà

A medium composition containing normal resting glucose that supports differentiation of primary human airway cells

Scientific Reports(2022)10.1038/s41598-022-05446-x

N/A

0DataRank · unranked

15 citations

Candela Manfredi, Kristen F. Easley, Lionel Watkins, William R. Hunt, Steven L. Goudy +4 more

Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient‐derived xenografts

Cancer Reports(2022)10.1002/cnr2.1708

N/A

0DataRank · unranked

3 citations

Annette Ehrhardt, Bhagelu R. Achyut, Disha Joshi, Melissa Gilbert‐Ross, Chunzi Huang +6 more

Engineered tRNAs suppress nonsense mutations in cells and in vivo

Nature(2023)10.1038/s41586-023-06133-1

N/A

0DataRank · unranked

135 citations

Elizabeth Cheresh Allen, Nikhil Bharti, Marcos Davyt, Disha Joshi, Carlos G. Pérez‐García +22 more

High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo

Journal of Controlled Release(2023)10.1016/j.jconrel.2023.04.005

N/A

0DataRank · unranked

66 citations

Melissa P. Lokugamage, Regina Rab, Alejandro J. Da Silva Sanchez, Hyejin Kim, Afsane Radmand +14 more

Elexacaftor/VX-445–mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105242

N/A

0DataRank · unranked

28 citations

Eli Fritz McDonald, Carleen Mae P. Sabusap, Bibek Timalsina, Disha Joshi, Jeong S. Hong +4 more

Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS‐CoV ‐2 infection and COVID ‐19 disease severity

The FASEB Journal(2023)10.1096/fj.202300077r

N/A

0DataRank · unranked

5 citations

Candela Manfredi, Frauke Degenhardt, Joseph Conway, Michael Horwath, Courtney McCracken +33 more

Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.04.527134

N/A

0DataRank · unranked

8 citations

Eli Fritz McDonald, Carleen Mae P. Sabusap, Bibek Timalsina, Disha Joshi, Jeong S. Hong +4 more

326 Modulator response of rare CFTR missense variants not approved for elexacaftor-tezacaftor-ivacaftor

Journal of Cystic Fibrosis(2023)10.1016/s1569-1993(23)01253-5

N/A

0DataRank · unranked

0 citations

András Rab, Eric J. Sorscher, Jeong S. Hong, Deepak Joshi

280 Induced pluripotent stem cell–based airway epithelial platform for investigating personalized responses to CFTR modulators

Journal of Cystic Fibrosis(2023)10.1016/s1569-1993(23)01208-0

N/A

0DataRank · unranked

0 citations

András Rab, Shunji Suzuki, Richard Bertrand, Stefan Winkler, S. Ponnaluri +12 more

287 A synonymous polymorphism associated with rare CFTR variants confers alterations to protein biogenesis, pharmacologic response, and clinical phenotype

Journal of Cystic Fibrosis(2023)10.1016/s1569-1993(23)01214-6

N/A

0DataRank · unranked

0 citations

Jeremy B. C. Jackson, Anne Winters, Deepak Joshi, Giovana Bampi, Eric J. Sorscher +3 more

242 An open-label trial to evaluate elexacaftor-tezacaftor-ivacaftor and induced pluripotent stem cell–derived model systems in individuals with residual CFTR activity

Journal of Cystic Fibrosis(2023)10.1016/s1569-1993(23)01171-2

N/A

0DataRank · unranked

0 citations

George M. Solomon, Shingo Suzuki, András Rab, C. Barillà, Arlene A. Stecenko +11 more

Translation velocity determines the efficacy of engineered suppressor tRNAs on pathogenic nonsense mutations

Nature Communications(2024)10.1038/s41467-024-47258-9

N/A

0DataRank · unranked

23 citations

Leonardo Santos, Marcos Davyt, Stine Behrmann, Marie Eichholtz, Alejandro Jiménez‐Sánchez +6 more

Mutation accumulation in H. sapiens F508del CFTR countermands dN/dS type genomic analysis

PLoS ONE(2024)10.1371/journal.pone.0305832

N/A

0DataRank · unranked

5 citations

Janice M. Tindall, Samuel R. Tindall, Eric J. Sorscher, Jeong S. Hong

Nanoparticle delivery of a prodrug-activating bacterial enzyme leads to anti-tumor responses

Nature Communications(2025)10.1038/s41467-025-58548-1

N/A

0DataRank · unranked

14 citations

Liming Lian, Regina Rab, Yuning Hou, Afsane Radmand, Hyejin Kim +15 more

Reconstitution of CFTR ubiquitination identifies lysine-420 as a regulator of cell surface residence and current

Biochemistry and Biophysics Reports(2025)10.1016/j.bbrep.2025.102393

N/A

0DataRank · unranked

1 citations

Xuemei Zeng, Jeong S. Hong, Disha Joshi, Zhengrong Yang, Fan Jiang +4 more

Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures

Journal of Virology(2020)10.1128/jvi.00985-20

N/A

0DataRank · unranked

333 citations

Philipp Ralfs, Tatiana Chirkova, Amit A. Upadhyay, Matthew G. Zimmerman, Shamika Bedoya +16 more

Barriers to the Pharmacologic Rescue of W1282X CFTR

Biochemistry(2025)10.1021/acs.biochem.5c00590

N/A

0DataRank · unranked

0 citations

András Rab, Disha Joshi, Ashlyn G. Winters, JaNise J Jackson, Samuel A. Molina +8 more

Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction

Molecular Therapy(2020)10.1016/j.ymthe.2020.04.021

N/A

0DataRank · unranked

78 citations

Ana M. Crane, Varada Anirudhan, C. Barillà, Nadine Matthias, Scott H. Randell +11 more

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors

Cancer Chemotherapy and Pharmacology(2020)10.1007/s00280-019-04018-7

N/A

0DataRank · unranked

13 citations

Paula W. Allan, William R. Waud, Jeong S. Hong, Melissa Gilbert‐Ross, Bhagelu R. Achyut +6 more

Leflunomide Prevents Alveolar Fluid Clearance Inhibition by Respiratory Syncytial Virus

UNC Libraries(2020)10.17615/wwbt-fs61

N/A

0DataRank · unranked

0 citations

Lee M. Graves, Ian C. Davis, Xiaodong Zhao, James A. Fortenberry, Eric J. Sorscher +5 more

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

UNC Libraries(2020)10.17615/7bhd-4s41

N/A

0DataRank · unranked

0 citations

Ana P. C. Rodrigues, John R. Riordan, Gergely L. Lukács, Jeffery W. Kelly, William R. Skach +18 more