Samuel K. McBrayer

Also affiliated with Allen Institute for Brain Science, Southwestern Medical Center, Children's Medical Center, Southwestern Medical Center, The University of Texas Southwestern Medical Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis”.

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

Nature Communications(2021)10.1038/s41467-021-24859-2

N/A

6.7DataRank · unranked

258 citations

Barbara Scott Nelson, Lin Lin, Emily L. Yarosz, Christopher J. Halbrook, Samuel A. Kerk +29 more

Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production

Cell chemical biology(2023)10.1016/j.chembiol.2023.01.005

N/A

0.767DataRank · unranked

18 citations

Wentian Wang, Alex Sternisha, Chase D. Corley, Hua-Yu Leo Wang, Xiaoyu Wang +10 more

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

Cancer Cell(2022)10.1016/j.ccell.2022.07.011

N/A

0.732DataRank · unranked

131 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +46 more

Establishment of patient-derived organoid models of lower-grade glioma

Neuro-Oncology(2021)10.1093/neuonc/noab273

N/A

0.692DataRank · unranked

100 citations

Cylaina Bird, Joseph Buehler, Lauren C. Gattie, Milan R. Savani, Alex Sternisha +14 more

Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity

Science(2024)10.1126/science.adl6173

N/A

0.686DataRank · unranked

96 citations

Hiroshi Kondo, Ashwin V. Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab +33 more

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470443

N/A

0.611DataRank · unranked

11 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +38 more

EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation

Nature Cell Biology(2022)10.1038/s41556-022-00962-4

N/A

0.564DataRank · unranked

42 citations

Ke Gong, Nicole A. Beckley, Yue Zhang, Xiaoyao Yang, Rati Chkheidze +25 more

Chromosomal instability in adult-type diffuse gliomas

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01420-w

N/A

0.494DataRank · unranked

26 citations

Jamie M. Walker, Kalil G. Abdullah, Samuel K. McBrayer, Mariano S. Viapiano, Zarmeen Mussa +4 more

Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.29.542774

N/A

0.385DataRank · unranked

12 citations

Mohamad El Shami, Lauren C. Gattie, Bailey Smith, William H. Hicks, Skyler Oken +14 more

Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment

Neuro-Oncology(2025)10.1093/neuonc/noaf248

N/A

0.269DataRank · unranked

5 citations

Mohamad El Shami, Kenji Miki, Lauren C. Gattie, Bailey Smith, William H. Hicks +19 more

Matched three-dimensional organoids and two-dimensional cell lines of melanoma brain metastases mirror response to targeted molecular therapy

Scientific Reports(2024)10.1038/s41598-024-76583-8

N/A

0.241DataRank · unranked

4 citations

Lauren C. Gattie, Mohamad El Shami, Jeffrey I. Traylor, Diwakar Davar, Yana G. Najjar +4 more

Matched three-dimensional organoids and two-dimensional cell lines of melanoma brain metastases mirror response to targeted molecular therapy

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.18.576318

N/A

0.241DataRank · unranked

4 citations

Lauren C. Gattie, Jeffrey I. Traylor, Diwakar Davar, Yana G. Najjar, Timothy E. Richardson +3 more

Protocol to establish a genetically engineered mouse model of IDH1-mutant astrocytoma

STAR Protocols(2023)10.1016/j.xpro.2023.102281

N/A

0.208DataRank · unranked

3 citations

J Lee, Adam C. Wang, Januka Khanal, Wenhua Gao, William G. Kaelin +2 more

Mutant IDH silences GSX2 to reprogram neural progenitor cell fate and promote gliomagenesis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.12.667486

N/A

0.104DataRank · unranked

1 citations

Diana D. Shi, Lei Guo, Ethan Neumann, Michael M. Levitt, Pranita Kaphle +28 more

Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.15.676412

N/A

0.104DataRank · unranked

1 citations

Kenji Miki, Charles K. Edgar, Shuangcheng Alivia Wu, Yi Xiao, Milan R. Savani +49 more

L-2-hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.16.649033

N/A

0DataRank · unranked

0 citations

Xun Wang, Ashley Solmonson, Ling Cai, Yi Xiao, Alpaslan Tasdogan +18 more

TMOD-06. CREATION OF PATIENT-DERIVED LOWER GRADE GLIOMA ORGANOID MODELS FOR PERSONALIZED TREATMENT RESPONSE ASSESSMENT

Neuro-Oncology(2021)10.1093/neuonc/noab196.868

N/A

0DataRank · unranked

3 citations

Joseph Buehler, Cylaina Bird, Milan R. Savani, Alex Sternisha, Michael M. Levitt +4 more

A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470644

N/A

0DataRank · unranked

0 citations

Jakub Kaplan, Huy Nguyen, Sylwia A. Stopka, Milan R. Savani, Michael S. Regan +16 more

Emerging roles of nucleotide metabolism in cancer

Trends in cancer(2023)10.1016/j.trecan.2023.04.008

N/A

0DataRank · unranked

70 citations

Milan R. Savani, Kalil G. Abdullah, Samuel K. McBrayer, Diana D. Shi

Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis

Cell Metabolism(2024)10.1016/j.cmet.2024.11.005

N/A

0DataRank · unranked

177 citations

Xuelian Ren, Yae Eun Park, Huixu Feng, Xinlei Sheng, Xiaohan Song +13 more

Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis

Blood(2024)10.1182/blood.2024025690

N/A

0DataRank · unranked

8 citations

An Vu, Abigail K Freer, Karanpreet Singh Bhatia, Dongxue Wang, Milan R. Savani +15 more

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

Nature Communications(2020)10.1038/s41467-020-15051-z

N/A

0DataRank · unranked

105 citations

Aditi Sharma, Abhinav Achreja, Claudia L. Edgar, Changyong Wei, Arusha Siddiqa +12 more