Li Chen

Also affiliated with Southwest University, University of Michigan, University of Florida, Affiliated Hospital of Qingdao University, Wuhan Children's Hospital, Florida College

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.273Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants

Bioinformatics(2024)10.1093/bioinformatics/btae578

Top 57%

0.273DataRank

Top 57%4 citations

Yi Xia, Javlon Nizomov, Yunlong Liu, Zhigang Li, Qing Lu +2 more

Papers

Driven by 50 papers — median percentile 21. Top paper: “Proteolysis of a nucleotide excision repair protein by the 26S proteasome”.

Proteolysis of a nucleotide excision repair protein by the 26S proteasome

Current Genetics(2002)10.1007/s00294-002-0332-9

N/A

3.9DataRank · unranked

79 citations

Tatiana Ortolan, Li Chen, Kiran Madura, Kevin S. Sweder, Lori Lommel

Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

Nature Cell Biology(2023)10.1038/s41556-023-01194-w

N/A

2.3DataRank · unranked

175 citations

Liming Pei, Jeffrey M. Spraggins, Michael Angelo, James P. Carson, Nils Gehlenborg +95 more

A novel deep learning method for predictive modeling of microbiome data

Briefings in Bioinformatics(2020)10.1093/bib/bbaa073

N/A

1.8DataRank · unranked

52 citations

Tathagata Bhattacharya, Yuchao Jiang, Xiao Qin, Yue Wang, Yunlong Liu +3 more

Gut microbiota dysbiosis contributes to the development of hypertension

Microbiome(2017)10.1186/s40168-016-0222-x

N/A

1.1DataRank · unranked

1721 citations

Fangqing Zhao, Yidan Wang, Junru Chen, Jie Tao, Gang Tian +14 more

Multi-task deep autoencoder to predict Alzheimer’s disease progression using temporal DNA methylation data in peripheral blood

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.10.016

N/A

1.0DataRank · unranked

28 citations

Andrew J. Saykin, Bing Yao, Fengdi Zhao, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Li Chen

Coactivator Recruitment of AhR/ARNT1

International Journal of Molecular Sciences(2014)10.3390/ijms150611100

N/A

0.943DataRank · unranked

23 citations

Li Chen, Futoshi Shibasaki, Alexander Endler

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

Cell(2025)10.1016/j.cell.2025.10.043

N/A

0.529DataRank · unranked

33 citations

Tao Liu, Zhen Zhang, Bai Zhang, Vladislav A. Petyuk, Li Chen +55 more

Identification of pathological pathways centered on circRNA dysregulation in association with irreversible progression of Alzheimer’s disease

Genome Medicine(2024)10.1186/s13073-024-01404-6

N/A

0.459DataRank · unranked

12 citations

Yangping Li, Huifeng Shen, Paula Martínez-Feduchi, Xingyu Ji, Peng Teng +6 more

Ten-eleven translocation protein 1 modulates medulloblastoma progression

Genome biology(2021)10.1186/s13059-021-02352-9

N/A

0.418DataRank · unranked

9 citations

Yunhee Kang, Yujing Li, Li Chen, Li Lin, Nicholas D. Johnson +19 more

MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants

Bioinformatics(2024)10.1093/bioinformatics/btae578

Top 57%

0.273DataRank

Top 57%4 citations

Yi Xia, Javlon Nizomov, Yunlong Liu, Zhigang Li, Qing Lu +2 more

High-impact pain predicts subjective cognitive decline and interacts with APOE4 genotype in the development of objective cognitive impairment

Journal of Pain(2025)10.1016/j.jpain.2025.105564

N/A

0.165DataRank · unranked

2 citations

Glenn E. Smith, Li Chen, Yenisel Cruz‐Almeida, Javier Tamargo

More than Meets the Eye: Untargeted Metabolomics and Lipidomics Reveal Complex Pathways Spurred by Activation of Acid Resistance Mechanisms in Escherichia coli

Journal of Proteome Research(2022)10.1021/acs.jproteome.2c00459

N/A

0DataRank · unranked

7 citations

Li Chen, Jiangjiang Zhu, Andrew Gold

DeepPerVar: a multimodal deep learning framework for functional interpretation of genetic variants in personal genome

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.10.487809

N/A

0DataRank · unranked

1 citations

Li Chen, Ye Wang

Multi-task deep autoencoder to predict Alzheimer’s disease progression using temporal DNA methylation data in peripheral blood

medRxiv(2022)10.1101/2022.04.02.22273346

N/A

0DataRank · unranked

0 citations

Li Chen

TIVAN-indel: A computational framework for annotating and predicting noncoding regulatory small insertion and deletion

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.28.509993

N/A

0DataRank · unranked

0 citations

Li Chen, Aman Agarwal

“It's a lot of things”: Household material hardship among Black and Hispanic parents of children with cancer

Pediatric Blood & Cancer(2023)10.1002/pbc.30485

N/A

0DataRank · unranked

12 citations

Alexandria Hawkins, Anna Revette, Li Chen, Niya Xiong, Emanuele Mazzola +7 more

TIVAN-indel: a computational framework for annotating and predicting non-coding regulatory small insertions and deletions

Bioinformatics(2023)10.1093/bioinformatics/btad060

N/A

0DataRank · unranked

12 citations

Fengdi Zhao, Yuchao Jiang, Li Chen, Aman Agarwal

Destin2: Integrative and cross-modality analysis of single-cell chromatin accessibility data

Frontiers in Genetics(2023)10.3389/fgene.2023.1089936

N/A

0DataRank · unranked

2 citations

Jin Seok Lee, Lihao Wang, Kevin Lin, Wenwen Mei, Li Chen +2 more

Spatial Metabolome Lipidome and Glycome from a Single brain Section

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.22.550155

N/A

0DataRank · unranked

8 citations

Xin Ma, Cameron J. Shedlock, Terrymar Medina, Tara R. Hawkinson, Lei Wu +13 more

The distinct roles of MSH2 and MLH1 in basal-like breast cancer and immune modulation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.20.549745

N/A

0DataRank · unranked

2 citations

Jiao Mo, Nicholas Borcherding, Sung Duk Jo, Heather R Kates, Edward H. Cho +12 more

MetaVision3D: Automated Framework for the Generation of Spatial Metabolome Atlas in 3D

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.27.568931

N/A

0DataRank · unranked

2 citations

Cameron J. Shedlock, Terrymar Medina, Roberto A. Ribas, Harrison A. Clarke, Tara R. Hawkinson +10 more

Data from DNMT3B Expression Might Contribute to CpG Island Methylator Phenotype in Colorectal Cancer

(2023)10.1158/1078-0432.c.6517612

N/A

0DataRank · unranked

0 citations

Kaori Shima, Natsumi Irahara, Shoko Kure, Yoshifumi Baba, Gregory J. Kirkner +9 more

CD74 Promotes Cyst Growth and Renal Fibrosis in Autosomal Dominant Polycystic Kidney Disease

Cells(2024)10.3390/cells13060489

N/A

0DataRank · unranked

13 citations

Alice Cheng, Li Chen, Xiaoyan Li, Ewud Agborbesong, Vicente E. Torres +3 more

scaDA: A novel statistical method for differential analysis of single-cell chromatin accessibility sequencing data

PLoS Computational Biology(2024)10.1371/journal.pcbi.1011854

N/A

0DataRank · unranked

7 citations

Xin Ma, Bing Yao, Qing‐Yi Lu, Li Chen, Fengdi Zhao

Deep5hmC: predicting genome-wide 5-hydroxymethylcytosine landscape via a multimodal deep learning model

Bioinformatics(2024)10.1093/bioinformatics/btae528

N/A

0DataRank · unranked

7 citations

Sai Ritesh Thela, Fengdi Zhao, Bing Yao, Zhexing Wen, Peng Jin +3 more

Combination screen in multi-cell type tumor spheroids reveals interaction between aryl hydrocarbon receptor antagonists and E1 ubiquitin-activating enzyme inhibitor

SLAS DISCOVERY(2024)10.1016/j.slasd.2024.100186

N/A

0DataRank · unranked

7 citations

Nathan P. Coussens, Thomas Silvers, Eric M. Jones, Li Chen, Jianwen Fang +5 more

Identification of brain region-specific landscape and functions of clustered circRNAs in Alzheimer’s disease using circMeta2

Communications Biology(2024)10.1038/s42003-024-07060-1

N/A

0DataRank · unranked

3 citations

Yangping Li, Li Chen, Bing Yao, Fengdi Zhao

scaDA: A Novel Statistical Method for Differential Analysis of Single-Cell Chromatin Accessibility Sequencing Data

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.21.576570

N/A

0DataRank · unranked

2 citations

Xin Ma, Bing Yao, Li Chen, Fengdi Zhao

Deep5hmC: Predicting genome-wide 5-Hydroxymethylcytosine landscape via a multimodal deep learning model

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.04.583444

N/A

0DataRank · unranked

1 citations

Sai Ritesh Thela, Fengdi Zhao, Bing Yao, Zhexing Wen, Peng Jin +3 more

MPRAVarDB: an online database and web server for exploring regulatory effects of genetic variants

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.02.587790

Top 100%

0DataRank

Top 100%0 citations

Weijia Jin, Yi Xia, Yunlong Liu, Zhigang Li, Li Chen +1 more

In silico generation and augmentation of regulatory variants from massively parallel reporter assay using conditional variational autoencoder

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.25.600715

N/A

0DataRank · unranked

0 citations

Yi Xia, Sai Ritesh Thela, Yunlong Liu, Li Chen, Weijia Jin

Spatial mapping of the brain metabolome lipidome and glycome

Nature Communications(2025)10.1038/s41467-025-59487-7

N/A

0DataRank · unranked

31 citations

Xin Ma, Cameron J. Shedlock, Terrymar Medina, Tara R. Hawkinson, Lei Wu +13 more

Glycogen drives tumour initiation and progression in lung adenocarcinoma

Nature Metabolism(2025)10.1038/s42255-025-01243-8

N/A

0DataRank · unranked

22 citations

Tara R. Hawkinson, Cameron J. Shedlock, Terrymar Medina, Roberto A. Ribas, Lei Wu +26 more

Per- and polyfluoroalkyl substances (PFAS) disrupt gut microbiome composition and metabolism in metabolic syndrome: Evidence from a host-free in vitro colonic model

Environmental Pollution(2025)10.1016/j.envpol.2025.127189

N/A

0DataRank · unranked

6 citations

Shiqi Zhang, Huan Zhang, Li Chen, Shuaixin Gao, Mengyang Xu +3 more

Constitutive activation of the Src-family kinases Fgr and Hck enhances the tumor burden of acute myeloid leukemia cells in immunocompromised mice

Scientific Reports(2025)10.1038/s41598-024-83740-6

N/A

0DataRank · unranked

4 citations

Li Chen, Giancarlo Gonzalez-Areizaga, Thomas E. Smithgall, Sherry T. Shu

A myeloid Tet2-IL-1β axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation

Immunity(2025)10.1016/j.immuni.2025.10.012

N/A

0DataRank · unranked

4 citations

Ankit Malik, Veronica Locher, Shaina McGrath, Sarah Zabala, Hardik Grover +6 more

Opposing roles for myeloid and smooth muscle cell STING in pulmonary hypertension

JCI Insight(2025)10.1172/jci.insight.184792

N/A

0DataRank · unranked

2 citations

S.T. Virk, Aline C. Oliveira, Matthew D. Alves, Chunhua Fu, Yutao Zhang +16 more

Polymerase Ѳ inhibitors combinations with approved and investigational agents in patient-derived tumor multi-cell type (mct) spheroids

Experimental and Molecular Pathology(2025)10.1016/j.yexmp.2025.104978

N/A

0DataRank · unranked

2 citations

Thomas S. Dexheimer, Li Chen, Thomas Silvers, Eric M. Jones, Nathan P. Coussens +3 more

A novel Bayesian hierarchical model for detecting differential circadian pattern in transcriptomic applications

Briefings in Bioinformatics(2025)10.1093/bib/bbaf139

N/A

0DataRank · unranked

0 citations

Haocheng Ding, Zhiguang Huo, Li Chen, Yutao Zhang

BayesCNet: Bayesian inference for cell type-specific regulatory networks leveraging cell type hierarchy in single-cell data

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.11.675686

N/A

0DataRank · unranked

0 citations

Arkaprava Roy, Weijia Jin, Leeana D. Peters, Todd M. Brusko, Qing Lu +4 more

A nanotrap improves survival in severe sepsis by attenuating hyperinflammation

Nature Communications(2020)10.1038/s41467-020-17153-0

N/A

0DataRank · unranked

73 citations

Xiaojing Wang, Lili Wang, Qinghe Meng, Dandan Guo, Li Chen +5 more

Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines

Briefings in Bioinformatics(2020)10.1093/bib/bbaa135

N/A

0DataRank · unranked

54 citations

Zhiwen Jiang, Yang Chen, Li Chen, Aziz Sancar, Yuchao Jiang +1 more

Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.04.024729

N/A

0DataRank · unranked

13 citations

Zhiwen Jiang, Yang Chen, Li Chen, Aziz Sancar, Yuchao Jiang +1 more

Single nucleus RNA-sequencing defines unexpected diversity of cholinergic neuron types in the adult mouse spinal cord

Nature Communications(2021)10.1038/s41467-021-22691-2

N/A

0DataRank · unranked

162 citations

Zoe Piccus, Sangeetha Hareendran, Hanna Silberberg, Li Chen, Yajun Zhang +3 more

5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer’s disease

Cell Reports(2021)10.1016/j.celrep.2021.109042

N/A

0DataRank · unranked

61 citations

Junyu Chen, Emily C. Bruggeman, Feng Wang, Yangping Li, Chongchong Xu +8 more

WEVar: a novel statistical learning framework for predicting noncoding regulatory variants

Briefings in Bioinformatics(2021)10.1093/bib/bbab189

N/A

0DataRank · unranked

9 citations

Yuchao Jiang, Bing Yao, Kun Huang, Yunlong Liu, Yue Wang +4 more

Accurate identification of circRNA landscape and complexity reveals their pivotal roles in human oligodendroglia differentiation

Genome biology(2022)10.1186/s13059-022-02621-1

N/A

0DataRank · unranked

29 citations

Feng Wang, Peng Teng, Li Ku, Li Chen, Yue Feng +2 more

DeepPHiC: predicting promoter-centered chromatin interactions using a novel deep learning approach

Bioinformatics(2022)10.1093/bioinformatics/btac801

N/A

0DataRank · unranked

17 citations

Li Chen, Aman Agarwal

Early Wnt Signaling Activation Promotes Inner Ear Differentiation via Cell Caudalization in Mouse Stem Cell-Derived Organoids

Stem Cells(2022)10.1093/stmcls/sxac071

N/A

0DataRank · unranked

15 citations

Li Chen, Sunita Singh, Andrew K. Groves, Karl R. Koehler, Xue Zhong Liu +2 more

DeepPerVar: a multi-modal deep learning framework for functional interpretation of genetic variants in personal genome

Bioinformatics(2022)10.1093/bioinformatics/btac696

N/A

0DataRank · unranked

15 citations

Li Chen, Ye Wang

Li Chen

Indexed papers

Top data-sharing exemplar

Papers