John M. Denu

Also affiliated with University of Wisconsin–Madison, Wisconsin Institutes for Discovery, Morgridge Institute for Research, University of Wisconsin Carbone Cancer Center, Institute on Aging

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 37 papers. Top paper: “Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6”.

Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6

Nature Communications(2020)10.1038/s41467-020-19018-y

N/A

1.6DataRank · unranked

64 citations

Jie Zheng, Jessica L. Feldman, Mark A. Klein, Vyacheslav I. Kuznetsov, Craig L. Peterson +3 more

Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice

Nature Metabolism(2021)10.1038/s42255-021-00466-9

N/A

0.783DataRank · unranked

184 citations

Spencer A. Haws, Cara L. Green, Mikaela Koller, Mitchell T. Lavarias, Nicole E. Richardson +12 more

Metabolism and the Epigenome: A Dynamic Relationship

Trends in Biochemical Sciences(2020)10.1016/j.tibs.2020.04.002

N/A

0.701DataRank · unranked

106 citations

Cassandra M. Leech, John M. Denu, Spencer A. Haws

Intrinsic catalytic properties of histone H3 lysine-9 methyltransferases preserve monomethylation levels under low S-adenosylmethionine

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104938

N/A

0.487DataRank · unranked

15 citations

Lillian J. Miller, Diego Rojas La Luz, Vyacheslav I. Kuznetsov, Raymond C. Trievel, Gheorghe Crăciun +2 more

SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype

Brain Communications(2022)10.1093/braincomms/fcac002

N/A

0.470DataRank · unranked

22 citations

Nicola Salvatore Orefice, Alexis J. Lawton, M Ma, Samantha L. Shapiro, Sue Y. Yi +9 more

A needed nomenclature for nucleosomes

Molecular Cell(2025)10.1016/j.molcel.2025.08.029

N/A

0.396DataRank · unranked

13 citations

Geneviève Almouzni, Andrew J. Andrews, Karim-Jean Armache, C.H. Arrowsmith, Sung Hee Baek +33 more

Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activity

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.015103

N/A

0.373DataRank · unranked

11 citations

Josue Baeza, Ramón Hurtado‐Guerrero, Thomas Hicks, Ignacio Delso, Cristina Hernández-Ruiz +6 more

The role of ATP citrate lyase in myelin formation and maintenance

Glia(2024)10.1002/glia.24620

N/A

0.338DataRank · unranked

5 citations

Seongsik Won, Eric A. Armstrong, Aaron J. Cooper, Amulya Suresh, R. Rivera +5 more

Acss2 Deletion Reveals Functional Versatility via Tissue-Specific Roles in Transcriptional Regulation

International Journal of Molecular Sciences(2023)10.3390/ijms24043673

N/A

0.330DataRank · unranked

8 citations

Dharmendra Kumar Soni, John R. Moffett, Jishnu K.S. Krishnan, Abhilash P. Appu, Sarani Ghoshal +6 more

Nucleic acid sequence contributes to remodeler-mediated targeting of histone H2A.Z

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.06.570360

N/A

0.104DataRank · unranked

1 citations

Leonidas Pierrakeas, Lirong Chan, Shalvi Chowdhury, Vyacheslav I. Kuznetsov, John M. Denu +2 more

Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism

Communications Biology(2021)10.1038/s42003-021-01992-8

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0DataRank · unranked

22 citations

Alexis J. Lawton, Gulpreet Kaur, Varuna C. Banduseela, William E. Kamm, Aparna Lakkaraju +3 more

Tandem histone methyltransferase upregulation defines a unique aggressive prostate cancer phenotype

British Journal of Cancer(2021)10.1038/s41416-021-01398-7

N/A

0DataRank · unranked

6 citations

Joseph Gawdzik, Andrew Truong, Glenn O. Allen, Wei Huang, Tariq A. Khemees +6 more

Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association

GeroScience(2021)10.1007/s11357-021-00479-y

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0DataRank · unranked

4 citations

Akilavalli Narasimhan, Alexis Adrián, Ankur Kumar, Cara L. Green, Carolina Soto-Palma +30 more

Histone Acid Extraction and High Throughput Mass Spectrometry to Profile Histone Modifications in Arabidopsis thaliana

Current Protocols(2022)10.1002/cpz1.527

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0DataRank · unranked

14 citations

James A. Dowell, Dean Sanders, Jianjun Jiang, John M. Denu, Xuehua Zhong +1 more

SIRT3 deficiency decreases oxidative-metabolism capacity but increases lifespan under caloric restriction

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.09.491205

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0DataRank · unranked

0 citations

Yiming Qin, Paul R. van Ginkel, Vivian Fu, James M. Vann, Alexis J. Lawton +7 more

Potent activation of NAD + -dependent deacetylase Sirt7 by nucleosome binding

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.11.491540

N/A

0DataRank · unranked

0 citations

Wallace H. Liu, Mark A. Klein, John M. Denu, Vyacheslav I. Kuznetsov

The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse

Communications Biology(2023)10.1038/s42003-023-05311-1

N/A

0DataRank · unranked

20 citations

Katherine A. Overmyer, Alexis J. Lawton, Ildikó Kasza, Samantha L. Shapiro, Patricia Gallego‐Muñoz +5 more

Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7**

Angewandte Chemie International Edition(2023)10.1002/anie.202314597

N/A

0DataRank · unranked

16 citations

Alexander L. Nielsen, Iben Jensen, Tobias Hansen, Line A. Ryberg, Samuel T. Jameson +6 more

DOT1L is a barrier to histone acetylation during reprogramming to pluripotency

Science Advances(2023)10.1126/sciadv.adf3980

N/A

0DataRank · unranked

15 citations

Xiaoya Zhang, Spencer A. Haws, John M. Denu, Rupa Sridharan, Coral K. Wille

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

Oncotarget(2023)10.18632/oncotarget.28477

N/A

0DataRank · unranked

7 citations

Bing Yang, Tanaya A. Purohit, Jennifer L. Schehr, Anupama Singh, Marcelo Bigarella +5 more

Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide‐Activated Sirtuin 7**

Angewandte Chemie(2023)10.1002/ange.202314597

N/A

0DataRank · unranked

1 citations

Alexander L. Nielsen, Iben Jensen, Tobias Hansen, Line A. Ryberg, Samuel T. Jameson +6 more

Individual dietary amino acid restrictions induce distinct metabolic and chromatin states

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.06.570456

N/A

0DataRank · unranked

4 citations

Yang Liu, Cara L. Green, Krittisak Chaiyakul, Pragyan Mishra, Reji Babygirija +6 more

Protein restriction slows the development and progression of Alzheimer's disease in mice

Research Square(2023)10.21203/rs.3.rs-3342413/v1

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0DataRank · unranked

2 citations

Michelle M. Sonsalla, Jessica Han, Isabella James, Cara L. Green, Mariah F. Calubag +15 more

Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer’s disease

Nature Communications(2024)10.1038/s41467-024-49589-z

N/A

0DataRank · unranked

22 citations

Michelle M. Sonsalla, Jericha Mill, Isabella James, Jessica Han, Cara L. Green +17 more

Gut microbiota–derived metabolite trimethylamine N-oxide alters the host epigenome through inhibition of S-adenosylhomocysteine hydrolase

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110521

N/A

0DataRank · unranked

11 citations

Federico E. Rey, John M. Denu, Jessica Han

Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer’s disease

Nature Communications(2025)10.1038/s41467-025-62416-3

N/A

0DataRank · unranked

11 citations

Jessica Han, Michelle M. Sonsalla, Ryan Matoska, Mariah F. Calubag, Cara L. Green +13 more

Depletion of individual dietary amino acids induce distinct metabolic and chromatin states

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111074

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0DataRank · unranked

2 citations

Yang Liu, Cara L. Green, Krittisak Chaiyakul, Parag Mishra, Reji Babygirija +6 more

H2A.Z deposition by the SWR complex is stimulated by polyadenine DNA sequences in nucleosomes

PLoS Biology(2025)10.1371/journal.pbio.3003059

N/A

0DataRank · unranked

2 citations

Leonidas Pierrakeas, Lirong Chan, Shalvi Chowdhury, Emily de Onis, Vyacheslav I. Kuznetsov +3 more

Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence

Molecular Cell(2020)10.1016/j.molcel.2020.03.004

N/A

0DataRank · unranked

94 citations

Deyang Yu, Cunqi Ye, Coral K. Wille, Long C. Nguyen, Kimberly A. Krautkramer +11 more

Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators

Journal of Biological Chemistry(2020)10.1074/jbc.rev120.011438

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0DataRank · unranked

82 citations

John M. Denu, Mark A. Klein

Catalysis by protein acetyltransferase Gcn5

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms(2020)10.1016/j.bbagrm.2020.194627

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0DataRank · unranked

29 citations

John M. Denu, Brittany N. Albaugh

Gut Microbiome Variation Modulates the Effects of Dietary Fiber on Host Metabolism

Research Square(2020)10.21203/rs.3.rs-97357/v1

N/A

0DataRank · unranked

5 citations

Qilin Hong, Tzu-Wen Cross, Evan R. Hutchison, Jessica Han, Sydney P. Thomas +6 more

NUP98-PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to Inhibition of PHD Histone Reader Function

UNC Libraries(2020)10.17615/tzed-va89

N/A

0DataRank · unranked

0 citations

Sheryl M. Gough, John M. Denu, Paul S. Meltzer, Masahiro Onozawa, Fan Yang +11 more

Gut microbiome variation modulates the effects of dietary fiber on host metabolism

Microbiome(2021)10.1186/s40168-021-01061-6

N/A

0DataRank · unranked

180 citations

Qilin Hong, Tzu-Wen Cross, Evan R. Hutchison, Jessica Han, Sydney P. Thomas +6 more

Short-chain fatty acids activate acetyltransferase p300

eLife(2021)10.7554/elife.72171

N/A

0DataRank · unranked

140 citations

John M. Denu, Sydney P. Thomas

Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway

Scientific Reports(2021)10.1038/s41598-021-81447-6

N/A

0DataRank · unranked

27 citations

Yusi Cui, Megan M. Braun, Alexis J. Lawton, Nicklaus H. Robinson, Jennifer L. Peotter +8 more

Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology

Brain(2021)10.1093/brain/awab295

N/A

0DataRank · unranked

25 citations

Nicola Salvatore Orefice, Alexis J. Lawton, M Ma, Samantha L. Shapiro, Sue Y. Yi +9 more