Lauren E. Brown

Also affiliated with Levine Children's Hospital, University of Pennsylvania

Environmental ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 29 papers. Top paper: “Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer”.

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

Nature Communications(2020)10.1038/s41467-020-20054-x

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0DataRank · unranked

112 citations

Hagar Lavon, Rina Wassermann-Dozorets, Meirav Pevsner‐Fischer, Shimrit Mayer, Esther Wershof +15 more

Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F

Cell Reports(2020)10.1016/j.celrep.2020.02.002

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0DataRank · unranked

77 citations

Wenhan Zhang, Regina Cencic, Patrick B. F. O’Connor, Françis Robert, William G. Devine +8 more

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

Nature Communications(2020)10.1038/s41467-020-20183-3

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0DataRank · unranked

71 citations

Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila Marie Pimentel‐Elardo, Jen Fossen +17 more

Translation Inhibition by Rocaglates Activates a Species-Specific Cell Death Program in the Emerging Fungal Pathogen Candida auris

mBio(2020)10.1128/mbio.03329-19

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39 citations

Luke Whitesell, John A. Porco, Thomas Henkel, Lauren E. Brown, Nicole Robbins +2 more

Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

iScience(2021)10.1016/j.isci.2021.102845

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0DataRank · unranked

25 citations

Shivraj M. Yabaji, Oleksii S. Rukhlenko, Bidisha Bhattacharya, Emily Waligurski, Nandini Vallavoju +9 more

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling

Nature Communications(2022)10.1038/s41467-022-34081-3

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0DataRank · unranked

83 citations

Aviad Ben‐Shmuel, Meirav Pevsner‐Fischer, Gil Friedman, Oshrat Levi-Galibov, Subhiksha Nandakumar +24 more

Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication

Antiviral Research(2022)10.1016/j.antiviral.2022.105359

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0DataRank · unranked

15 citations

Mara Klöhn, Yannick Brüggemann, Lauren E. Brown, John A. Porco, Wenhan Zhang +6 more

Identification of Small Molecules with Improved Potency against Orthopoxviruses from Vaccinia to Smallpox

Antimicrobial Agents and Chemotherapy(2022)10.1128/aac.00841-22

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0DataRank · unranked

9 citations

Scott Seitz, Ashley V. Kondas, Paul T. Marcyk, Claire Marie Filone, Mohammad Mokbul Hossain +4 more

Inhibition of the Translation Initiation Factor eIF4A Enhances Tumor Cell Radiosensitivity

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-22-0037

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7 citations

Theresa Wechsler, Kayla Schwartz, Lauren E. Brown, John A. Porco, William G. Devine +5 more

Exploring the targeting spectrum of rocaglates among eIF4A homologs

RNA(2023)10.1261/rna.079318.122

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0DataRank · unranked

12 citations

Regina Cencic, Françis Robert, Lauren E. Brown, Minza Haque, Jordan Scott-Talib +5 more

Synthesis of Neocannabinoids Using Controlled Friedel–Crafts Reactions

The Journal of Organic Chemistry(2023)10.1021/acs.joc.3c01362

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8 citations

Richard Trilles, James McNeely, Lauren E. Brown, Aaron B. Beeler, John A. Porco +1 more

Discovery of pyrazolopyrrolidinones as potent, broad-spectrum inhibitors of Leishmania infection

Frontiers in Tropical Diseases(2023)10.3389/fitd.2022.1011124

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0DataRank · unranked

8 citations

Laura‐Isobel McCall, Miriam A. Giardini, Géraldine De Muylder, Diane Thomas, Adolfo García-Pérez +10 more

Synthesis of Neocannabinoids Using Controlled Friedel-Crafts Reactions

ChemRxiv(2023)10.26434/chemrxiv-2023-7wtzg

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0DataRank · unranked

2 citations

Richard Trilles, James McNeely, Lauren E. Brown, Aaron B. Beeler, John A. Porco +1 more

A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans

Microbiology Spectrum(2024)10.1128/spectrum.04095-23

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10 citations

Dustin Duncan, Kyle D. Reichl, Michael J. Smith, Wenyu Wang, John A. Porco +5 more

The MYCN 5′ UTR as a therapeutic target in neuroblastoma

Cell Reports(2024)10.1016/j.celrep.2024.114134

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5 citations

Lauren E. Brown, Ushashi Banerjee, Ruben Dries, Bandana Sharma, Alyssa L. Kennedy +3 more

Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis

Antiviral Research(2024)10.1016/j.antiviral.2024.105976

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0DataRank · unranked

5 citations

Wenhan Zhang, Michael Ricca, Alan Wacquiez, Autumn O Grimins, Regina Cencic +11 more

Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

ACS Central Science(2024)10.1021/acscentsci.4c01073

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0DataRank · unranked

5 citations

Ritesh Thakare, Shalaka Chitale, Alok Mishra, Stanley I. Goldstein, Alice C. Fan +10 more

Glabridin Hypnosis in Zebrafish Larvae Is Associated With Effects on Multiple Anesthetic Target Receptors

Anesthesia & Analgesia(2024)10.1213/ane.0000000000007318

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0DataRank · unranked

1 citations

Helen M. Hoyt, Kieran Bhave, Madyson Medeiros, Daniel Cho, Lauren E. Brown +4 more

Study protocol for ADHERE (Applying Directly observed therapy to HydroxyurEa to Realize Effectiveness): Using small business partnerships to deliver a scalable and novel hydroxyurea adherence solution to youth with sickle cell disease

PLoS ONE(2024)10.1371/journal.pone.0304644

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0DataRank · unranked

3 citations

Lauren E. Brown, Sebastian Seiguer, Katie Munshaw, Joseph R. Rausch, Sherif M. Badawy +5 more

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.19.590252

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0DataRank · unranked

2 citations

Alice C. Fan, Zihao Wang, Sai Kiran Naineni, Regina Cencic, Steve B. Garcia-Gutierrez +6 more

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia

UNC Libraries(2024)10.17615/w913-sr13

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0DataRank · unranked

0 citations

Jianwei Wang, A Charney, Vahram Haroutunian, Nancy Francoeur, Gil S.E +60 more

In vitro discovery of a therapeutic lead for HFMD from a library screen of rocaglates/aglains

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.30.615979

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0DataRank · unranked

0 citations

Angel Borge, Regina Ching Hua Lee, Cyrill Kafi Salim, Wenyu Wang, Michael Ricca +6 more

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays

Journal of Proteome Research(2025)10.1021/acs.jproteome.4c01129

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0DataRank · unranked

2 citations

Alice C. Fan, Zihao Wang, Sai Kiran Naineni, Regina Cencic, Steve B. Garcia-Gutierrez +6 more

Identification of natural products and synthetic analogs which inhibit microsporidia spores and prevent infection

Journal of Invertebrate Pathology(2025)10.1016/j.jip.2025.108492

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2 citations

Lauren E. Brown, Guoqing Pan, Junhong Wei, John A. Porco, Jie Chen +2 more

A cationic amphiphilic drug synergizes with strobilurin fungicides to control fungal-borne plant diseases

Cell chemical biology(2025)10.1016/j.chembiol.2025.05.008

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0DataRank · unranked

4 citations

Christopher Blackman, Mackenzie Eli William Loranger, Richard Trilles, Kalina Doytchinova-Weil, Stephen S. Scully +12 more

Connecting chemical structure to single cell signaling profiles

Communications Biology(2025)10.1038/s42003-025-08545-3

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0DataRank · unranked

1 citations

Madeline Hayes, Laura C. Geben, Rebecca A. Ihrie, Lauren E. Brown, John A. Porco +2 more

In Vitro Discovery of a Therapeutic Lead for HFMD From a Library Screen of Rocaglates/Aglains

Journal of Medical Virology(2025)10.1002/jmv.70228

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0DataRank · unranked

1 citations

Angel Borge, Regina Ching Hua Lee, Cyrill Kafi Salim, Wenyu Wang, Michael Ricca +6 more

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials(2025)10.1002/adfm.202422047

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0DataRank · unranked

1 citations

Lauren E. Brown, Christopher M. Madl, Ping Zhou

Structural Basis for the Improved RNA Clamping of Amidino-Rocaglates to eIF4A1

ACS Omega(2025)10.1021/acsomega.4c09421

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0DataRank · unranked

0 citations

Lauren E. Brown, James McNeely, Jerry Pelletier, John A. Porco, Karen N. Allen +1 more