Bart L. Staker

Also affiliated with Children’s Institute, Infectious Disease Research Institute, Joint Center for Structural Genomics, Seattle Children's Hospital

Materials ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 38 papers. Top paper: “Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials”.

Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c01795

N/A

0.406DataRank · unranked

14 citations

Kutub Ashraf, Melvin Delvillar, Tyler Eck, Raheel Fondekar, Edward B. Miller +15 more

High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development

Structure(2022)10.1016/j.str.2022.09.001

N/A

0.373DataRank · unranked

11 citations

Peter C. Gareiss, Jae‐Yeon Choi, Isaline Renard, Anasuya Pal, Yulia Surovsteva +14 more

A single Leishmania adenylate–forming enzyme of the ANL superfamily generates both acetyl- and acetoacetyl-CoA

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107879

N/A

0.241DataRank · unranked

4 citations

Taiwo E. Esan, Jonah Propp, Andrew Fuller, Drashti G. Daraji, Charles L. Lail +8 more

Versatile Imidazole Scaffold with Potent Activity against Multiple Apicomplexan Parasites

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00049

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0.165DataRank · unranked

2 citations

Jemma Montgomery, Mariana Laureano de Souza, Melvin Delvillar, Lyssa J. Weible, Mayuri Prabakaran +10 more

Site-Specific Incorporation of Clickable d-Mannose Derivatives in the Lipopolysaccharide Core of the Pathogen Brucella abortus

ACS Chemical Biology(2025)10.1021/acschembio.5c00202

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0.165DataRank · unranked

2 citations

A. Reboul, Rym Yahia Boudhar, Elodie Carlier, James W. Fairman, Tanguy Scaillet +6 more

Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans

Acta Crystallographica Section F Structural Biology Communications(2021)10.1107/s2053230x21012632

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0DataRank · unranked

3 citations

Kyndall Nicholas, Jeremy Young, Deborah G. Conrady, Stephen Mayclin, Sandhya Subramanian +4 more

Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204473119

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0DataRank · unranked

24 citations

Allison Maker, Andrew Vae Priest, David M. Dranow, Jenny N. Phan, Thomas E. Edwards +5 more

Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography

PNAS Nexus(2022)10.1093/pnasnexus/pgac163

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0DataRank · unranked

20 citations

Madison Bolejack, Leslayann Schecterson, Brad Hammerson, Jan Abendroth, Thomas E. Edwards +4 more

Targeting Pantothenate Kinase as an Effective Strategy for Antifungal Drug Development

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7671

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0DataRank · unranked

1 citations

Peter C. Gareiss, Jae‐Yeon Choi, Isaline Renard, Anasuya Pal, Yulia Surovsteva +14 more

Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx

Acta Crystallographica Section F Structural Biology Communications(2022)10.1107/s2053230x22002138

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0DataRank · unranked

1 citations

Bart L. Staker, Sandhya Subramanian, Jan Abendroth, Thomas E. Edwards, Peter J. Myler +3 more

Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.21.484361

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0DataRank · unranked

5 citations

Madison Bolejack, Leslayann Schecterson, Brad Hammerson, Jan Abendroth, Tom E Edwards +4 more

Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.06.483190

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0DataRank · unranked

1 citations

Allison Maker, Andrew Vae Priest, David M. Dranow, Jenny N. Phan, Thomas E. Edwards +5 more

Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts

Nature Communications(2023)10.1038/s41467-023-41119-7

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0DataRank · unranked

33 citations

Kamalakannan Vijayan, Rachael Zigweid, Michael K. Fenwick, Banumathi Sankaran, Wanlapa Roobsoong +8 more

Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00151

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0DataRank · unranked

6 citations

Alexandra R. Reers, Yi Liu, Rachael Zigweid, Banumathi Sankaran, Janis Shin +9 more

Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1

Acta Crystallographica Section F Structural Biology Communications(2023)10.1107/s2053230x23008002

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0DataRank · unranked

6 citations

Yagmur Konuk, Jordan O. Norman, Jan Abendroth, Thomas E. Edwards, Donald D. Lorimer +9 more

Identification of potent and selective N -myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.27.525941

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0DataRank · unranked

2 citations

Kamalakannan Vijayan, Rachael Zigweid, Michael K. Fenwick, Banumathi Sankaran, Wanlapa Roobsoong +8 more

Enolase inhibitors as therapeutic leads for Naegleria fowleri infection

PLoS Pathogens(2024)10.1371/journal.ppat.1012412

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0DataRank · unranked

13 citations

Victoria C. Yan, Cong-Dat Pham, Florian L. Müller, Samuel Kwain, Kerrick C. Rees +15 more

Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01594

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0DataRank · unranked

6 citations

Vitor M. Almeida, Jaryd Sullivan, Ian de Toledo, C.V. dos Reis, Micael Rodrigues Cunha +20 more

ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells

Journal of Virology(2024)10.1128/jvi.00102-24

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0DataRank · unranked

10 citations

Anna-Lena Rupp, Marie Schwerdtner, Dorothea Bestle, Anne Harbig, Amy De Rocher +7 more

Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens

Communications Biology(2024)10.1038/s42003-024-07175-5

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0DataRank · unranked

4 citations

Phillip G. Pierce, Jan Abendroth, Kayleigh F. Barrett, Lynn K. Barrett, Kalinga Bowatte +28 more

Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis

Acta Crystallographica Section F Structural Biology Communications(2024)10.1107/s2053230x2400356x

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0DataRank · unranked

3 citations

Prashit Parikh, Jan Abendroth, T.L. Arakaki, Matthew C. Clifton, Thomas E. Edwards +6 more

Enolase inhibitors as therapeutic leads for Naegleria fowleri infection

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.16.575558

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0DataRank · unranked

3 citations

Victoria C. Yan, Cong-Dat Pham, Florian L. Müller, Samuel Kwain, Kerrick C. Rees +14 more

Selective Bias Virtual Screening for Discovery of Promising Antimalarial Candidates targeting Plasmodium N-Myristoyltransferase

Research Square(2024)10.21203/rs.3.rs-3963523/v1

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0DataRank · unranked

1 citations

Bruna Katiele de Paula Sousa, Sunniva Sigurdardóttir, Catarina Bourgard, Joyce Villa Verde Bastos Borba, Leandro da Costa Clementino +9 more

Correction to “Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials”

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01411

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0DataRank · unranked

1 citations

Kutub Ashraf, Melvin Delvillar, Tyler Eck, Raheel Fondekar, Edward B. Miller +15 more

Bumped Kinase Inhibitors Inhibit both Toxoplasma gondii MAPKL1 and CDPK1

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00051

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0DataRank · unranked

8 citations

P. Holland Alday, Ryan Choi, Monique Khim, Bart L. Staker, Matthew A. Hulverson +5 more

A functional enzymatic assay as potential readout for a clinical trial of a schistosomiasis vaccine

npj Vaccines(2025)10.1038/s41541-024-01044-2

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0DataRank · unranked

3 citations

Mumtaz Yaseen Balkhi, Yasuko Ono, Jenn Davis, Naoko Doi, Aryandra Arya +14 more

The crystal structures of apo and tryptophan-bound tryptophanyl-tRNA synthetase from Neisseria gonorrhoeae

Acta Crystallographica Section F Structural Biology Communications(2025)10.1107/s2053230x25001311

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0DataRank · unranked

2 citations

David Song, Thomas E. Edwards, David M. Dranow, Donald D. Lorimer, Bart L. Staker +3 more

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor

Nature Communications(2025)10.1038/s41467-025-64183-7

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0DataRank · unranked

2 citations

Katy M. Alden, Jonah Propp, Drashti G. Daraji, Charles L. Lail, Michael E. Heene +10 more

Structure guided modification of 2-chloro-5-(ethyl-phenyl-sulfamoyl)-N-[2-(2-oxo-pyrrolidin-1-yl)-phenyl]-benzamide to afford selective inhibitors of Cryptosporidium parvum N-myristoyltransferase

Bioorganic & Medicinal Chemistry Letters(2025)10.1016/j.bmcl.2025.130092

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0DataRank · unranked

0 citations

Sophia Groustra, Michael K. Fenwick, Rachael Zigweid, Matthew A. Hulverson, Eric Owsley +6 more

Architecture of Pseudomonas aeruginosa glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2504757122

N/A

0DataRank · unranked

0 citations

Stephen J. Mayclin, Steve Seibold, Amy E. DeRocher, Sandhya Subramanian, Isabelle Phan +16 more

Crystal structures of Mycobacterium tuberculosis and Mycobacterium thermoresistibile glycyl-tRNA synthetases in various liganded states

PLoS ONE(2025)10.1371/journal.pone.0326500

N/A

0DataRank · unranked

0 citations

Amy E. DeRocher, Justin K. Craig, Elizabeth K. Harmon, Steve Seibold, Lijun Liu +9 more

Synthesis and evaluation of acyl-AMP phosphate isosteres as inhibitors of fungal acetyl CoA synthetase

Bioorganic & Medicinal Chemistry Letters(2025)10.1016/j.bmcl.2025.130389

N/A

0DataRank · unranked

0 citations

Andrew J. Jezewski, Katy M. Alden, Jonah Propp, Michael E. Heene, Calvin A Soldan +7 more

Structural analysis of CACHE domain of the McpA chemoreceptor from Leptospira interrogans

Biochemical and Biophysical Research Communications(2020)10.1016/j.bbrc.2020.10.013

N/A

0DataRank · unranked

4 citations

Mônica L. Vieira, Jan Abendroth, Tao Lin, Bart L. Staker, Peter J. Myler +2 more

Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens

UNC Libraries(2025)10.17615/awaa-8n71

N/A

0DataRank · unranked

0 citations

Ronaldo A. Pilli, K.P. Battaile, Ian de Toledo, Scott Lovell, Kevin D. Read +20 more

Identification of P218 as a Potent Inhibitor of Mycobacteria Ulcerans DHFR

ChemRxiv(2020)10.26434/chemrxiv.12899420.v1

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0DataRank · unranked

0 citations

Rachael Zigweid, Peter J. Myler, Stephen J. Mayclin, Rafael M. Couñago, Bart L. Staker +1 more

Identification of P218 as a Potent Inhibitor of Mycobacteria Ulcerans DHFR

ChemRxiv(2020)10.26434/chemrxiv.12899420

N/A

0DataRank · unranked

0 citations

Rachael Zigweid, Peter J. Myler, Stephen J. Mayclin, Rafael M. Couñago, Bart L. Staker +1 more

In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

Scientific Reports(2021)10.1038/s41598-021-83730-y

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0DataRank · unranked

33 citations

Sandhya Subramanian, David E. Kim, Michael Murphy, Deleah Pettie, Lauren Carter +20 more

Host-targeted Interventions as an Exciting Opportunity to Combat Malaria

Chemical Reviews(2021)10.1021/acs.chemrev.1c00062

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0DataRank · unranked

26 citations

Ling Wei, Elizabeth K. K. Glennon, Christa Mattocks, Natasha M. Bourgeois, Bart L. Staker +2 more