Irving C. Allen

Biochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 50 papers. Top paper: “Starting a Fire Without Flame: The Induction of Cell Death and Inflammation in Electroporation-Based Tumor Ablation Strategies”.

Starting a Fire Without Flame: The Induction of Cell Death and Inflammation in Electroporation-Based Tumor Ablation Strategies

Frontiers in Oncology(2020)10.3389/fonc.2020.01235

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81 citations

Natalie Beitel-White, Rafael V. Davalos, Irving C. Allen, Rebecca M. Brock

High-Frequency Irreversible Electroporation for Treatment of Primary Liver Cancer: A Proof-of-Principle Study in Canine Hepatocellular Carcinoma

Journal of Vascular and Interventional Radiology(2020)10.1016/j.jvir.2019.10.015

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53 citations

Timothy J. O’Brien, Melvin F. Lorenzo, Sheryl Coutermarsh‐Ott, Sabrina L. Barry, Krystina L. Stadler +6 more

Patient Derived Xenografts Expand Human Primary Pancreatic Tumor Tissue Availability for ex vivo Irreversible Electroporation Testing

Frontiers in Oncology(2020)10.3389/fonc.2020.00843

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24 citations

Natalie Beitel-White, Sheryl Coutermarsh‐Ott, Douglas J. Grider, Melvin F. Lorenzo, Veronica M. Ringel‐Scaia +5 more

Deletion of ripA Alleviates Suppression of the Inflammasome and MAPK by Francisella tularensis

UNC Libraries(2020)10.17615/nzdz-a982

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7 citations

Haitao Wen, Max Tze Han Huang, Debra J. Taxman, Jenny Pan Yun Ting, Irving C. Allen +9 more

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

UNC Libraries(2020)10.17615/93n9-cv93

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0 citations

Zhengmao Ye, Albert G Zimmermann, Beckley K. Davis, Timothy K. Eitas, Reid A Roberts +10 more

Characterization of NLRP12 during the Development of Allergic Airway Disease in Mice

UNC Libraries(2020)10.17615/hrt6-cf70

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Jenny P.-Y. Ting, Janelle C. Arthur, John D. Lich, Stephen L. Tilley, Reid A. Roberts +3 more

Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1

UNC Libraries(2020)10.17615/9k2c-q519

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Miriam Braunstein, Jenny P.-Y. Ting, Paul D. Hulseberg, Jessica R. McCann, Erin McElvania +3 more

Analysis of the Murine Immune Response to Pulmonary Delivery of Precisely Fabricated Nano- and Microscale Particles

UNC Libraries(2020)10.17615/5y5e-rh85

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Reid A. Roberts, Jenny P.‐Y. Ting, Irving C. Allen, Tammy W. Shen, Joseph M. DeSimone +1 more

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

UNC Libraries(2020)10.17615/hae9-8v21

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Erin McElvania, Irving C. Allen, Juliane Bubeck Wardenburg, Robin R. Craven, Joseph A. Duncan +3 more

The NLR Adaptor ASC/PYCARD Regulates DUSP10, Mitogen-activated Protein Kinase (MAPK), and Chemokine Induction Independent of the Inflammasome

UNC Libraries(2020)10.17615/cbwz-pm13

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Debra J. Taxman, Max Tze-Han Huang, Elizabeth Holley-Guthrie, Denis Gris, Irving C. Allen +4 more

Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome

UNC Libraries(2020)10.17615/swym-wb59

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Irving C. Allen, Claire M. Doerschuk, Joshua D. Hall, Stephen L. Tilley, Corey M. Jania +5 more

Plexin-B2 and Plexin-D1 in Dendritic Cells: Expression and IL-12/IL-23p40 Production

UNC Libraries(2020)10.17615/as28-3y82

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Scott E. Plevy, Erin C. Steinbach, Jenny P.‐Y. Ting, Adam Buntzman, Irving C. Allen +4 more

Analysis of NLRP3 in the Development of Allergic Airway Disease in Mice

UNC Libraries(2020)10.17615/n36e-cj27

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Beverly H. Koller, Corey M. Jania, Mildred Kwan, Erin M. Tekeppe, Justin E. Wilson +5 more

An orphaned Mce-associated membrane protein of M ycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters: OmamA functions in virulence and Mce stability

UNC Libraries(2020)10.17615/aemq-b084

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0 citations

Jennifer Hayden, Virginia Godfrey, Ellen F. Perkowski, Jessica R. McCann, Brittany K. Miller +4 more

Cooperation between Mast Cells and Neurons Is Essential for Antigen-Mediated Bronchoconstriction

UNC Libraries(2020)10.17615/5c7x-gh19

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0 citations

Irving C. Allen, John M. Hartney, Martina Kovářová, Dennis L. Murphy, Jürgen Wess +2 more

The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner

Viruses(2021)10.3390/v13061062

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145 citations

Seth A. Hawks, Matthew A. Crawford, Caitlin Woodson, Holly A. Morrison, Hannah Ivester +10 more

Immunological Effects of Histotripsy for Cancer Therapy

Frontiers in Oncology(2021)10.3389/fonc.2021.681629

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86 citations

Ruby Hutchison, Eli Vlaisavljevich, Irving C. Allen, Alissa Hendricks-Wenger

Histotripsy Ablation Alters the Tumor Microenvironment and Promotes Immune System Activation in a Subcutaneous Model of Pancreatic Cancer

IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control(2021)10.1109/tuffc.2021.3078094

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84 citations

Jacqueline Sereno, Jessica M. Gannon, Allison Zeher, Rebecca M. Brock, Natalie Beitel-White +6 more

Histotripsy Ablation in Preclinical Animal Models of Cancer and Spontaneous Tumors in Veterinary Patients: A Review

IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control(2021)10.1109/tuffc.2021.3110083

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34 citations

Lauren Arnold, Jessica M. Gannon, Alex Simon, Neha Singh, Hannah Sheppard +16 more

Isolation of a novel insect-specific flavivirus with immunomodulatory effects in vertebrate systems

Virology(2021)10.1016/j.virol.2021.07.004

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27 citations

Rose M. Langsjoen, Danielle L. Porier, Jesse H. Erasmus, Nicholas A. Bergren, Bethany G. Bolling +12 more

Establishing an immunocompromised porcine model of human cancer for novel therapy development with pancreatic adenocarcinoma and irreversible electroporation

Scientific Reports(2021)10.1038/s41598-021-87228-5

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21 citations

Kenneth N. Aycock, Margaret A. Nagai-Singer, Sheryl Coutermarsh‐Ott, Melvin F. Lorenzo, Jessica M. Gannon +13 more

Enemy of My Enemy: A Novel Insect-Specific Flavivirus Offers a Promising Platform for a Zika Virus Vaccine

Vaccines(2021)10.3390/vaccines9101142

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21 citations

Sarah N. Wilson, Dawn I. Auguste, Andrew Leber, Sheryl Coutermarsh‐Ott, Irving C. Allen +8 more

Generation of Tumor-activated T cells Using Electroporation

Bioelectrochemistry(2021)10.1016/j.bioelechem.2021.107886

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8 citations

Philip M. Graybill, Khan Mohammad Imran, Scott S. Verbridge, Irving C. Allen, Rafael V. Davalos +1 more

Focused ultrasound tumour ablation in small animal oncology

Veterinary and Comparative Oncology(2021)10.1111/vco.12742

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7 citations

Alayna N. Hay, Jennifer L. Carroll, Nikolaos Dervisis, Lauren Arnold, Sheryl Coutermarsh‐Ott +6 more

cGAS-STING Signaling Pathway Mediates Brain Trauma-Induced Type I Interferon Response

Research Square(2021)10.21203/rs.3.rs-855949/v1

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0 citations

Jing Ju, Erwin Kristobal Gudenschwager Basso, Eman Soliman, Swagatika Paul, Jiang Chen +8 more

Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis

UNC Libraries(2021)10.17615/k6ah-vy58

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0 citations

Justin E. Wilson, Jonathan T. Sullivan, Miriam Braunstein, Erin McElvania, John D. Lich +3 more

Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury

Frontiers in Molecular Neuroscience(2022)10.3389/fnmol.2022.852243

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55 citations

Jing Ju, Erwin Kristobal Gudenschwager Basso, Eman Soliman, Swagatika Paul, Jiang Chen +9 more

Mechanical High-Intensity Focused Ultrasound (Histotripsy) in Dogs With Spontaneously Occurring Soft Tissue Sarcomas

IEEE Transactions on Biomedical Engineering(2022)10.1109/tbme.2022.3201709

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33 citations

Ester Yang, Jessica M. Gannon, Hannah Sheppard, Sheryl Coutermarsh‐Ott, Timothy J. Ziemlewicz +7 more

High-Frequency Irreversible Electroporation (H-FIRE) Induced Blood–Brain Barrier Disruption Is Mediated by Cytoskeletal Remodeling and Changes in Tight Junction Protein Regulation

Biomedicines(2022)10.3390/biomedicines10061384

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25 citations

Yukitaka Kani, Melvin F. Lorenzo, Sabrina N. Campelo, Irving C. Allen, Jonathan Hinckley +6 more

Exploration of Novel Pathways Underlying Irreversible Electroporation Induced Anti-Tumor Immunity in Pancreatic Cancer

Frontiers in Oncology(2022)10.3389/fonc.2022.853779

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14 citations

Margaret A. Nagai-Singer, Rebecca M. Brock, Nastaran Alinezhadbalalami, Rafael V. Davalos, Irving C. Allen +1 more

Detecting DNA: An Overview of DNA Recognition by Inflammasomes and Protection against Bacterial Respiratory Infections

Cells(2022)10.3390/cells11101681

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6 citations

Justin W. Markov Madanick, Hannah Ivester, Irving C. Allen, Juselyn D. Tupik

NLRX1 Deficiency Alters the Gut Microbiome and Is Further Exacerbated by Adherence to a Gluten-Free Diet

Frontiers in Immunology(2022)10.3389/fimmu.2022.882521

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7 citations

Yang Liu, Kristin Eden, Margaret A. Nagai-Singer, Paul A. Wade, Irving C. Allen +1 more

Magic bubbles: utilizing histotripsy to modulate the tumor microenvironment and improve systemic anti-tumor immune responses

International Journal of Hyperthermia(2023)10.1080/02656736.2023.2244206

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37 citations

Anutosh Ganguly, Tamalika Paul, Manali Powar, Eli Vlaisavljevich, Clifford S. Cho +2 more

Ultrasound-guided noninvasive pancreas ablation using histotripsy: feasibility study in an in vivo porcine model

International Journal of Hyperthermia(2023)10.1080/02656736.2023.2247187

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19 citations

Khan Mohammad Imran, Alissa Hendricks-Wenger, Michael Edwards, Hannah Covell, Lauren Ruger +13 more

Ablative and Immunostimulatory Effects of Histotripsy Ablation in a Murine Osteosarcoma Model

Biomedicines(2023)10.3390/biomedicines11102737

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16 citations

Khan Mohammad Imran, Alissa Hendricks-Wenger, Jessica M. Gannon, Jacqueline Sereno, Alex Simon +6 more

NLRX1 functions as a tumor suppressor in Pan02 pancreatic cancer cells

Frontiers in Oncology(2023)10.3389/fonc.2023.1155831

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9 citations

Holly A. Morrison, Mackenzie K. Woolls, Katerina Leedy, Khan Mohammad Imran, Juselyn D. Tupik +2 more

Investigating cell death responses associated with histotripsy ablation of canine osteosarcoma

International Journal of Hyperthermia(2023)10.1080/02656736.2023.2279027

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9 citations

Elliana Vickers, Manali Patwardhan, Jessica M. Gannon, Lauren Ruger, Irving C. Allen +3 more

Successful In Situ Targeting of Pancreatic Tumors in a Novel Orthotopic Porcine Model Using Histotripsy

Ultrasound in Medicine & Biology(2023)10.1016/j.ultrasmedbio.2023.07.013

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8 citations

Jessica M. Gannon, Holly A. Morrison, Juselyn D. Tupik, Benjamin Tintera, Margaret A. Nagai-Singer +14 more

A hepatitis B virus core antigen‐based virus‐like particle vaccine expressing SARS‐CoV‐2 B and T cell epitopes induces epitope‐specific humoral and cell‐mediated immune responses but confers limited protection against SARS‐CoV‐2 infection

Journal of Medical Virology(2023)10.1002/jmv.28503

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9 citations

Harini Sooryanarain, C. Lynn Heffron, Seth A. Hawks, Tanya LeRoith, Thomas E. Cecere +12 more

Cellular Context Dictates the Suppression or Augmentation of Triple-Negative Mammary Tumor Metastasis by NLRX1

The Journal of Immunology(2023)10.4049/jimmunol.2200834

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4 citations

Mackenzie K. Woolls, Katerina Leedy, Alissa Hendricks-Wenger, Rebecca M. Brock, Sheryl Coutermarsh‐Ott +8 more

Nlrp12 deficiency alters gut microbiota and ameliorates Faslpr-mediated systemic autoimmunity in male mice

Frontiers in Immunology(2023)10.3389/fimmu.2023.1120958

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4 citations

Jiangdi Mao, Xavier Cabana-Puig, Jing Zhu, Brianna Swartwout, Michael Edwards +6 more

Humoral and T-cell-mediated responses to a pre-clinical Zika vaccine candidate that utilizes a unique insect-specific flavivirus platform

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.01.530296

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2 citations

Awadalkareem Adam, Lin Kang, Pawel Michalak, Juselyn D. Tupik, Matthew A. Santos +5 more

Irreversible electroporation promotes a pro-inflammatory tumor microenvironment and anti-tumor immunity in a mouse pancreatic cancer model

Frontiers in Immunology(2024)10.3389/fimmu.2024.1352821

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20 citations

Rebecca M. Brock, Natalie Beitel-White, Manali Powar, Katie Orr, Kenneth N. Aycock +10 more

NF-κB Inducing Kinase Attenuates Colorectal Cancer by Regulating Noncanonical NF-κB Mediated Colonic Epithelial Cell Regeneration

Cellular and Molecular Gastroenterology and Hepatology(2024)10.1016/j.jcmgh.2024.05.004

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13 citations

Kristin Eden, Brie Trusiano, Daniel E. Rothschild, Yufeng Qin, Paul A. Wade +8 more

Humoral and T-cell-mediated responses to an insect-specific flavivirus-based Zika virus vaccine candidate

PLoS Pathogens(2024)10.1371/journal.ppat.1012566

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7 citations

Awadalkareem Adam, Lin Kang, Pawel Michalak, Juselyn D. Tupik, Matthew A. Santos +8 more

Modulating the Cell Death Immune Response for Electroporation Treatments

Bioelectricity(2024)10.1089/bioe.2024.0019

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6 citations

Nastaran Alinezhadbalalami, Zaid S. Salameh, Kenneth N. Aycock, Irving C. Allen, Rafael V. Davalos +1 more

Not just for lymphoid cells: the role of the noncanonical NF-κB signaling pathway in early and late myelopoiesis with a focus on hypereosinophilic disorders

Journal of Leukocyte Biology(2024)10.1093/jleuko/qiae101

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3 citations

Kathy Zimmerman, Holly A. Morrison, Irving C. Allen, Brie Trusiano

Repurposing of lonafarnib as a treatment for SARS-CoV-2 infection

JCI Insight(2024)10.1172/jci.insight.182704

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1 citations

Parker Irvin, Seung Bum Park, Hannah Ivester, Inna Ricardo-Lax, Madeleine Leek +18 more

Non-Invasive Pancreas Ablation Using Histotripsy: Pre-clinical Safety Study in an In Vivo Porcine Model

Ultrasound in Medicine & Biology(2025)10.1016/j.ultrasmedbio.2025.07.026

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3 citations

Tamalika Paul, Khan Mohammad Imran, Michael Edwards, Timothy J. Ziemlewicz, Brie Trusiano +19 more

The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice

Respiratory Research(2025)10.1186/s12931-025-03349-9

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2 citations

Pavel Solopov, Caitlin Woodson, Irving C. Allen, Ivan Akhrymuk, Maryna Akhrymuk +9 more