Christopher J. Bakkenist

Also affiliated with UPMC Hillman Cancer Center, University of Pittsburgh Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 17 papers. Top paper: “Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice”.

Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice

PLoS ONE(2023)10.1371/journal.pone.0282722

N/A

0.208DataRank · unranked

3 citations

Siying Guo, Yoko Shuda, A. Bhaswanth Chakka, Lora H. Rigatti, Guangyi Zhao +9 more

Phase Ib study of berzosertib, carboplatin, gemcitabine, and pembrolizumab in patients with squamous nonsmall lung cancer (ETCTN 10313)

The Oncologist(2025)10.1093/oncolo/oyaf373

N/A

0.109DataRank · unranked

1 citations

Benjamin Schluger, Hong Wang, James Ohr, Daniel P. Petro, Alexander D. Fuld +10 more

Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression

Cell Reports(2022)10.1016/j.celrep.2022.111371

N/A

0DataRank · unranked

25 citations

Frank P. Vendetti, Andrew J. Cipriano, Pinakin Pandya, Joshua J. Deppas, Tatiana N. Moiseeva +12 more

Dose-dependent bioavailability, absorption-rate limited elimination, and tissue distribution of the ATR inhibitor BAY-1895344 (elimusertib) in mice

Cancer Chemotherapy and Pharmacology(2022)10.1007/s00280-022-04436-0

N/A

0DataRank · unranked

8 citations

Joshua J. Deppas, Jianxia Guo, Robert A. Parise, David A. Clump, Christopher J. Bakkenist +2 more

Thymidine rescues ATR kinase inhibition induced deoxyuridine contamination in genomic DNA, cell death, and Type 1 interferon expression

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.24.481821

N/A

0DataRank · unranked

1 citations

Frank P. Vendetti, Andrew J. Cipriano, Pinakin Pandya, Joshua J. Deppas, Tatiana N. Moiseeva +12 more

Short-course but not prolonged treatment with ATR inhibitor AZD6738 integrates with radiotherapy to generate a tumor antigen-specific CD8 + T cell expansion in the periphery

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.11.487886

N/A

0DataRank · unranked

0 citations

D.A. Clump, Sandra Schamus-Haynes, Maria diMayorca, Naveed M. Islam, Jina Chang +3 more

The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy

JCI Insight(2023)10.1172/jci.insight.165615

N/A

0DataRank · unranked

36 citations

Pinakin Pandya, David A. Clump, Sandra Schamus-Haynes, Meysam Tavakoli, Maria diMayorca +6 more

Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice

Cancer Chemotherapy and Pharmacology(2024)10.1007/s00280-024-04675-3

N/A

0DataRank · unranked

4 citations

Brian F. Kiesel, Jianxia Guo, Robert A. Parise, David A. Clump, David Z. D’Argenio +3 more

Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.04.588079

N/A

0DataRank · unranked

1 citations

Frank P. Vendetti, Joseph El-Ghoubaira, Sudipta Pathak, Joshua J. Deppas, Reyna Jones +12 more

Nuclear cholesterol regulates nuclear size and DNA damage responses in cancer stem cells

Neuro-Oncology(2025)10.1093/neuonc/noaf110

N/A

0DataRank · unranked

5 citations

Suchet Taori, Shruti Bhargava, Sisi Lai, Cuiqing Zhong, Shira Yomtoubian +20 more

Comparative in vivo toxicology of ATR inhibitors ceralasertib, elimusertib, and berzosertib alone and in combination with ionizing radiation

Toxicology and Applied Pharmacology(2025)10.1016/j.taap.2025.117375

N/A

0DataRank · unranked

4 citations

Brian F. Kiesel, Jianxia Guo, Lora H. Rigatti, Joseph D. Latoche, Anthony R. Green +7 more

DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110857

N/A

0DataRank · unranked

2 citations

Weiyan Jia, Sang Hwa Kim, Mark Scalf, Claire E. Boos, Yuhong Chen +9 more

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2A Low tumors via increased macrophage phagocytosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.08.637227

N/A

0DataRank · unranked

3 citations

Aidan R. Cole, Jeff Danielson, Jimmy P. Xu, Drew E. Hurd, Akash Kishore +33 more

Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.28.666960

N/A

0DataRank · unranked

1 citations

Pinakin Pandya, Carina R. Sclafani, Reyna Jones, D. Ivanov, Robert W. Sobol +2 more

Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.24.312058

N/A

0DataRank · unranked

1 citations

Kalena A. Grimes, Kenneth Kim, Emilie Branche, Christopher J. Bakkenist, William H. DePas +3 more

Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons

NAR Cancer(2025)10.1093/narcan/zcaf054

N/A

0DataRank · unranked

0 citations

Pinakin Pandya, Carina R. Sclafani, Sudipta Pathak, Raquel Buj, Reyna Jones +5 more

Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

PLoS Pathogens(2021)10.1371/journal.ppat.1009252

N/A

0DataRank · unranked

29 citations

Kalena A. Grimes, Kenneth Kim, Emilie Branche, Christopher J. Bakkenist, William H. DePas +3 more