Richard L. Huganir

Also affiliated with Johns Hopkins Medicine

NeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.848Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A compendium of human gene functions derived from evolutionary modelling

Nature(2025)10.1038/s41586-025-08592-0

Top 24%

0.848DataRank

Top 24%35 citations

Huaiyu Mi, Pascale Gaudet, Anushya Muruganujan, Suzanna Lewis, Dustin Ebert +95 more

Papers

Driven by 49 papers — median percentile 76. Top paper: “Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors”.

Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors

eLife(2021)10.7554/elife.66809

N/A

1.8DataRank · unranked

83 citations

Richard H. Roth, Han L. Tan, Qianwen Zhu, Alexei M. Bygrave, Elena Lopez-Ortega +8 more

A compendium of human gene functions derived from evolutionary modelling

Nature(2025)10.1038/s41586-025-08592-0

Top 24%

0.848DataRank

Top 24%35 citations

Huaiyu Mi, Pascale Gaudet, Anushya Muruganujan, Suzanna Lewis, Dustin Ebert +95 more

Low-Dose Perampanel Rescues Cortical Gamma Dysregulation Associated With Parvalbumin Interneuron GluA2 Upregulation in Epileptic Syngap1+/− Mice

Biological Psychiatry(2020)10.1016/j.biopsych.2019.12.025

N/A

0DataRank · unranked

61 citations

Simon G. Ammanuel, Pavel A. Kipnis, Yoichi Araki, Richard L. Huganir, Shilpa D. Kadam +1 more

SynGAP splice variants display heterogeneous spatio‐temporal expression and subcellular distribution in the developing mammalian brain

Journal of Neurochemistry(2020)10.1111/jnc.14988

N/A

0DataRank · unranked

59 citations

Adriana Roca‐Fernández, Murat Kılınç, Elena Serrano, Rita Reig‐Viader, Yoichi Araki +5 more

Contribution of D1R-expressing neurons of the dorsal dentate gyrus and Cav1.2 channels in extinction of cocaine conditioned place preference

Neuropsychopharmacology(2020)10.1038/s41386-019-0597-z

N/A

0DataRank · unranked

13 citations

Charlotte C. Bavley, Delaney K. Fischer, Alexander P. Walsh, Arlene Martínez-Rivera, Jonathan Hackett +7 more

An Optimized CRISPR/Cas9 Approach for Precise Genome Editing in Neurons

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.30.402883

N/A

0DataRank · unranked

6 citations

Alexei M. Bygrave, Richard H. Roth, Richard C. Johnson, Richard L. Huganir, Huaqiang Fang

The immediate early gene Arc is not required for hippocampal long-term potentiation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.03.893305

N/A

0DataRank · unranked

2 citations

Lenora J. Volk, Samuel F. Cooke, Mark F. Bear, Richard L. Huganir, Jason D. Shepherd +1 more

The Immediate Early Gene Arc Is Not Required for Hippocampal Long-Term Potentiation

Journal of Neuroscience(2021)10.1523/jneurosci.0008-20.2021

N/A

0DataRank · unranked

50 citations

Lenora J. Volk, Samuel F. Cooke, Mark F. Bear, Richard L. Huganir, Jason D. Shepherd +1 more

AMPA Receptors Exist in Tunable Mobile and Immobile Synaptic FractionsIn Vivo

eNeuro(2021)10.1523/eneuro.0015-21.2021

N/A

0DataRank · unranked

28 citations

Richard H. Roth, Elena Lopez-Ortega, Han L. Tan, Richard L. Huganir, Haiwen Chen

Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice

Translational Psychiatry(2021)10.1038/s41398-020-01194-6

N/A

0DataRank · unranked

25 citations

Juan José Rodríguez Gotor, Minae Niwa, Irina N. Krasnova, Abby Adamczyk, Mei Han +8 more

All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2105388118

N/A

0DataRank · unranked

25 citations

Su Z. Hong, Seung‐Eon Roh, Shiyong Huang, Jiechao Zhou, Michelle Bridi +10 more

KIBRA-PKCγ signaling pathway modulates memory performance in mice and humans

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.26.465926

N/A

0DataRank · unranked

3 citations

Qiang Chen, Austin R. Graves, Hana L. Goldschmidt, Richard C. Johnson, Daniel R. Weinberger +2 more

An Ultrasensitive PKA Biosensor for Multi‐modal Kinase Activity Detection and High‐Resolution Imaging in Awake Mice

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.05431

N/A

0DataRank · unranked

0 citations

Jinfan Zhang, Ingie Hong, Albert Mo, Richard H. Roth, Brian Tenner +10 more

Cell-specific regulation of gene expression using splicing-dependent frameshifting

Nature Communications(2022)10.1038/s41467-022-33523-2

N/A

0DataRank · unranked

39 citations

Alexei M. Bygrave, Clayton P. Santiago, Rogger P. Carmen‐Orozco, Vickie Trinh, Minzhong Yu +31 more

Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina

Journal of Lipid Research(2022)10.1016/j.jlr.2022.100247

N/A

0DataRank · unranked

9 citations

Hana L. Goldschmidt, Brendan N. Lilley, Alexei M. Bygrave, Richard C. Johnson, Richard L. Huganir +3 more

Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity

Frontiers in Synaptic Neuroscience(2022)10.3389/fnsyn.2022.855673

N/A

0DataRank · unranked

7 citations

Hana L. Goldschmidt, Qianqian Ma, Lauren DeVine, Robert N. Cole, Richard L. Huganir +2 more

Cell-specific regulation of gene expression using splicing-dependent frameshifting

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.02.481623

N/A

0DataRank · unranked

2 citations

Alexei M. Bygrave, Clayton P. Santiago, Rogger P. Carmen‐Orozco, Vickie Trinh, Minzhong Yu +29 more

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

Research Square(2022)10.21203/rs.3.rs-1416757/v1

N/A

0DataRank · unranked

0 citations

Jonathan P. Ling, Alexei M. Bygrave, Clayton P. Santiago, Rogger P. Carmen‐Orozco, Vickie Trinh +28 more

Mouse models of SYNGAP1 -related intellectual disability

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2308891120

N/A

0DataRank · unranked

22 citations

Elizabeth E. Gerber, Kacey E. Rajkovich, Ingie Hong, Richard C. Johnson, Hey‐Kyoung Lee +3 more

Cross-modality supervised image restoration enables nanoscale tracking of synaptic plasticity in living mice

Nature Methods(2023)10.1038/s41592-023-01871-6

N/A

0DataRank · unranked

21 citations

Austin R. Graves, Gabrielle I Coste, Richard L. Huganir, Dwight E. Bergles, Adam S. Charles +2 more

Btbd11 supports cell-type-specific synaptic function

Cell Reports(2023)10.1016/j.celrep.2023.112591

N/A

0DataRank · unranked

14 citations

Ayesha Sengupta, Ella P. Jackert, Mehroz Ahmed, Beloved Adenuga, Erik D. Nelson +7 more

Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad064

N/A

0DataRank · unranked

11 citations

Gabrielle I Coste, Javier Redding‐Ochoa, Haidan Guo, Austin R. Graves, Juan C. Troncoso +2 more

Experience-Induced Remodeling of the Hippocampal Post-synaptic Proteome and Phosphoproteome

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100661

N/A

0DataRank · unranked

11 citations

Taewook Kang, Alexei M. Bygrave, Martin R. Larsen, Richard L. Huganir, Seok Heo

ICA69 regulates activity-dependent synaptic strengthening and learning and memory

Frontiers in Molecular Neuroscience(2023)10.3389/fnmol.2023.1171432

N/A

0DataRank · unranked

5 citations

Chih‐Ming Chen, Richard L. Huganir, Shu‐Ling Chiu

Structure of Transmembrane AMPA Receptor Regulatory Protein Subunit γ2

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.28.569079

N/A

0DataRank · unranked

4 citations

Alejandra Montaño Romero, Richard L. Huganir, Edward C. Twomey, W. Dylan Hale

Allosteric Competition and Inhibition in AMPA Receptors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.28.569057

N/A

0DataRank · unranked

4 citations

Alejandra Montaño Romero, Cuauhtémoc U. Gonzalez, Vasanthi Jayaraman, Albert Y. Lau, Richard L. Huganir +2 more

SynGAP regulates synaptic plasticity and cognition independent of its catalytic activity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.06.552111

N/A

0DataRank · unranked

3 citations

Kacey E. Rajkovich, Elizabeth E. Gerber, Timothy R. Gamache, Richard C. Johnson, Hai Tran +5 more

Transcriptional Signatures of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer’s Disease

medRxiv(2023)10.1101/2023.09.12.23295440

N/A

0DataRank · unranked

2 citations

Ryan G. Palaganas, E. Michael Meyer, Javier Redding‐Ochoa, Olga Pletnikova, Haidan Guo +5 more

Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.20.557316

N/A

0DataRank · unranked

2 citations

Suha Khan, Robert A. Kozol, Yoichi Araki, Sheyum Syed, Richard L. Huganir +2 more

SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity

Science(2024)10.1126/science.adk1291

N/A

0DataRank · unranked

89 citations

Kacey E. Rajkovich, Elizabeth E. Gerber, Timothy R. Gamache, Richard C. Johnson, Hai Tran +6 more

Stimulus-dependent synaptic plasticity underlies neuronal circuitry refinement in the mouse primary visual cortex

Cell Reports(2024)10.1016/j.celrep.2024.113966

N/A

0DataRank · unranked

6 citations

Jung Yoon Choi, Ingie Hong, Richard H. Roth, Robert H. Cudmore, Richard L. Huganir +1 more

Context-dependent hyperactivity in syngap1a and syngap1b zebrafish models of SYNGAP1-related disorder

Frontiers in Molecular Neuroscience(2024)10.3389/fnmol.2024.1401746

N/A

0DataRank · unranked

5 citations

Suha Khan, Robert A. Kozol, Yoichi Araki, Sheyum Syed, Richard L. Huganir +2 more

WWC2 modulates GABAA-receptor-mediated synaptic transmission, revealing class-specific mechanisms of synapse regulation by WWC family proteins

Cell Reports(2024)10.1016/j.celrep.2024.114841

N/A

0DataRank · unranked

4 citations

Julia R. Wilkerson, Richard C. Johnson, Richard L. Huganir, Lenora J. Volk, Thomas Dunham

Syngap1 and the development of murine neocortical progenitor cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.18.629233

N/A

0DataRank · unranked

2 citations

Ingie Hong, Ulrich Müller, Richard L. Huganir, Soraia Barão

Modulation of GABA A receptor trafficking by WWC2 reveals class-specific mechanisms of synapse regulation by WWC family proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.11.584487

N/A

0DataRank · unranked

0 citations

Julia R. Wilkerson, Richard C. Johnson, Richard L. Huganir, Lenora J. Volk, Thomas Dunham

Endosomal hyper-acidification via proton-activated chloride channel deletion in neurons impairs AMPA receptor endocytosis and LTD

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.27.615471

N/A

0DataRank · unranked

0 citations

Junhua Yang, Bian Liu, Chaohua Jiang, Nicholas Koylass, Zhe Zhang +4 more

DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning

Nature Neuroscience(2025)10.1038/s41593-025-01923-4

N/A

0DataRank · unranked

21 citations

Gabriela Michel, Yizhi Wang, Verónica Hernandez, Jonathan B. Grimm, Jin‐Yong Park +18 more

Transcriptional signatures of hippocampal tau pathology in primary age-related tauopathy and Alzheimer’s disease

Cell Reports(2025)10.1016/j.celrep.2025.115422

N/A

0DataRank · unranked

14 citations

Ryan G. Palaganas, E. Michael Meyer, Javier Redding‐Ochoa, Olga Pletnikova, Haidan Guo +5 more

Dissociation of SYNGAP1 enzymatic and structural roles: Intrinsic excitability and seizure susceptibility

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2427288122

N/A

0DataRank · unranked

14 citations

Blaise Clarke, Ingie Hong, Richard L. Huganir, Julia Brill

Loss of the proton-activated chloride channel in neurons impairs AMPA receptor endocytosis and LTD via endosomal hyper-acidification

Cell Reports(2025)10.1016/j.celrep.2025.115302

N/A

0DataRank · unranked

8 citations

Junhua Yang, Bian Liu, Chaohua Jiang, Nicholas Koylass, Zhe Zhang +4 more

Syngap1 and the development of murine neocortical progenitor cells

Nature Communications(2025)10.1038/s41467-025-66069-0

N/A

0DataRank · unranked

3 citations

Yijun Xu, Ingie Hong, Ulrich Mueller, Richard L. Huganir, Soraia Barão

Structure of transmembrane AMPA receptor regulatory protein subunit γ2

Nature Communications(2025)10.1038/s41467-025-56027-1

N/A

0DataRank · unranked

5 citations

Alejandra Montaño Romero, Nicholas Koylass, Collin R. Warrick, Zhaozhu Qiu, Richard L. Huganir +2 more

Dynamic extracellular interactions with AMPA receptors

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2517436122

N/A

0DataRank · unranked

2 citations

Casey N. Barber, Santosh Renuse, Jevon Cutler, Simion Kreimer, Alexei M. Bygrave +5 more

Dissociation of SYNGAP1 Enzymatic and Structural Roles: Intrinsic Excitability and Seizure Susceptibility

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.14.633019

N/A

0DataRank · unranked

1 citations

Blaise Clarke, Ingie Hong, Richard L. Huganir, Julia Brill

Dynamic extracellular interactions with AMPA receptors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.11.664166

N/A

0DataRank · unranked

1 citations

Casey N. Barber, Santosh Renuse, Jevon Cutler, Simion Kreimer, Alexei M. Bygrave +5 more

Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.30.697121

N/A

0DataRank · unranked

1 citations

Yu-Min Huang, Chih‐Ching Chung, R T Johnson, Cheng-Ya Tsai, Yuhan Chen +5 more

SynGAP isoforms differentially regulate synaptic plasticity and dendritic development

eLife(2020)10.7554/elife.56273

N/A

0DataRank · unranked

111 citations

Ingie Hong, Timothy R. Gamache, Shaowen Ju, Leonardo Collado‐Torres, Joo Heon Shin +2 more

Single-cell long-read sequencing of the experience-induced transcriptome

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.12.674885

N/A

0DataRank · unranked

0 citations

Paul W. Hook, Richard L. Huganir, Winston Timp, Sheridan Cavalier

An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice

Nature Chemical Biology(2020)10.1038/s41589-020-00660-y

N/A

0DataRank · unranked

110 citations

Bian Liu, Ingie Hong, Albert Mo, Richard H. Roth, Brian Tenner +9 more

Richard L. Huganir

Indexed papers

Top data-sharing exemplar

Papers