🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

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Authors
Charles M. Perou

Charles M. Perou

University of North Carolina at Chapel Hill

ORCID: 0000-0001-9827-2247

Also affiliated with UNC Lineberger Comprehensive Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

43.3Author DataRank

Indexed papers

23in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 23 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Comprehensive genomic characterization of squamous cell lung cancers

Nature(2012)10.1038/nature11404

Top 1%

11.0DataRank

Top 1%4036 citations

Gad Getz, Stephen E. Schumacher, Petar Stojanov, Chang‐Jiun Wu, Hailei Zhang +326 more

Papers

Driven by 183 papers — median percentile 46. Top paper: “Proteogenomics connects somatic mutations to signalling in breast cancer”.

Proteogenomics connects somatic mutations to signalling in breast cancer

Nature(2016)10.1038/nature18003

N/A

12.7DataRank · unranked

1777 citations

Philipp Mertins, D. R. Mani, Kelly V. Ruggles, Michael A. Gillette, Karl R. Clauser +31 more

Comprehensive genomic characterization of squamous cell lung cancers

Nature(2012)10.1038/nature11404

Top 1%

11.0DataRank

Top 1%4036 citations

Gad Getz, Stephen E. Schumacher, Petar Stojanov, Chang‐Jiun Wu, Hailei Zhang +326 more

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

Cell(2018)10.1016/j.cell.2018.02.052

Top 2%

8.1DataRank

Top 2%3980 citations

Katherine A. Hoadley, Laila M. Poisson, Alexander J. Lazar, Andrew D. Cherniack, Albert J. Kovatich +866 more

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

Cell(2018)10.1016/j.cell.2018.03.033

Top 3%

6.4DataRank

Top 3%447 citations

Matthew H. Bailey, Hoifung Poon, Vesteinn Thorsson, Antonio Colaprico, Andreas Bender +883 more

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

Cell Reports(2018)10.1016/j.celrep.2018.03.046

N/A

5.5DataRank · unranked

186 citations

Francisco Sanchez-Vega, Konnor C. La, Joshua Armenia, Walid K. Chatila, Augustin Luna +869 more

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

Nature Communications(2017)10.1038/ncomms14864

N/A

4.9DataRank · unranked

155 citations

Shunqiang Li, Philipp Mertins, Song Cao, Harsha P. Gunawardena, Kelly V. Ruggles +40 more

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Nature(2020)10.1038/s41586-020-1965-x

Top 5%

4.6DataRank

Top 5%668 citations

Federico Abascal, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj +1240 more

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

UNC Libraries(2020)10.17615/exht-jc34

N/A

4.0DataRank · unranked

104 citations

H. Wong, X. Li, D. L. Rimm, S. G. Hilsenbeck, M. C. Gutierrez +18 more

Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis

Nature Cancer(2022)10.1038/s43018-022-00491-x

Top 9%

2.4DataRank

Top 9%114 citations

Toshinori Hinoue, Gregory Wheeler, Benjamin Kelly, Ana C. Garrido-Castro, Tomás Pascual +53 more

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

Cancer Research(2022)10.1158/0008-5472.can-21-2807

Top 10%

2.1DataRank

Top 10%91 citations

Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy +13 more

Integrated genomic analyses of ovarian carcinoma

Nature(2011)10.1038/nature10166

N/A

1.3DataRank · unranked

8094 citations

Debra Bell, Andrew Berchuck, Michael J. Birrer, Jeremy Chien, D. W. Cramer +268 more

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Cancer Cell(2010)10.1016/j.ccr.2009.12.020

N/A

1.3DataRank · unranked

7682 citations

Katherine A. Hoadley, Elizabeth Purdom, Victoria Wang, Yuan Qi, Matthew D. Wilkerson +31 more

Oncogenic Signaling Pathways in The Cancer Genome Atlas

Cell(2018)10.1016/j.cell.2018.03.035

N/A

1.2DataRank · unranked

3322 citations

Marco Mina, Joshua Armenia, Walid K. Chatila, Augustin Luna, Konnor C. La +891 more

Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

Science Translational Medicine(2010)10.1126/scitranslmed.3001451

N/A

1.0DataRank · unranked

823 citations

Martin L. Sos, Danila Seidel, Charles M. Perou, Thomas Zander, Johannes M. Heuckmann +66 more

Inherited predisposition to breast cancer in the Carolina Breast Cancer Study

npj Breast Cancer(2021)10.1038/s41523-020-00214-4

Top 23%

0.869DataRank

Top 23%13 citations

Süleyman Gülsüner, Ming K. Lee, Melissa A. Troester, Andrew F. Olshan, H. Shelton Earp +3 more

Lung Squamous Cell Carcinoma mRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types

Clinical Cancer Research(2010)10.1158/1078-0432.ccr-10-0199

N/A

0.853DataRank · unranked

294 citations

Xiaoying Yin, Katherine A. Hoadley, Yufeng Liu, Michele C. Hayward, Christopher R. Cabanski +15 more

Correction: Corrigendum: Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

Nature Communications(2017)10.1038/ncomms15479

N/A

0.843DataRank · unranked

11 citations

Shunqiang Li, Philipp Mertins, Song Cao, Harsha P. Gunawardena, Kelly V. Ruggles +40 more

Endocrine-Sensitive Disease Rate in Postmenopausal Patients With Estrogen Receptor–Rich/ERBB2-Negative Breast Cancer Receiving Neoadjuvant Anastrozole, Fulvestrant, or Their Combination

JAMA Oncology(2024)10.1001/jamaoncol.2023.6038

N/A

0.819DataRank · unranked

21 citations

Vera J. Suman, Souzan Sanati, Kiran Vij, Meenakshi Anurag, A. Marilyn Leitch +25 more

Microscaled proteogenomic methods for precision oncology

Nature Communications(2020)10.1038/s41467-020-14381-2

N/A

0.722DataRank · unranked

122 citations

Eric J. Jaehnig, Karsten Krug, Beom‐Jun Kim, Alexander B. Saltzman, Doug W. Chan +28 more

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

UNC Libraries(2020)10.17615/43yk-w772

Top 31%

0.649DataRank

Top 31%17 citations

Qing Lai, Pavel Zuloaga, Amber M. Froehlich, Edward S. Chen, Jian Huang +24 more

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

UNC Libraries(2020)10.17615/0xdg-yq72

N/A

0.552DataRank · unranked

6 citations

Shunqiang Li, Philipp Mertins, Song Cao, Harsha P. Gunawardena, Kelly V. Ruggles +40 more

Virus expression detection reveals RNA-sequencing contamination in TCGA

BMC Genomics(2020)10.1186/s12864-020-6483-6

N/A

0.542DataRank · unranked

36 citations

David Marron, Daniel P. Hollern, Lisle E. Mose, Katherine A. Hoadley, Corbin D. Jones +4 more

Evaluating the efficacy of a priming dose of cyclophosphamide prior to pembrolizumab to treat metastatic triple negative breast cancer

Journal for ImmunoTherapy of Cancer(2022)10.1136/jitc-2021-003427

N/A

0.500DataRank · unranked

27 citations

Mark G. Woodcock, Amanda E.D. Van Swearingen, Dominic T. Moore, Maria J. Sambade, Sonia J. Laurie +22 more

Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

UNC Libraries(2020)10.17615/jcyr-9v75

N/A

0.442DataRank · unranked

18 citations

Candace Shelton, Matthew Meyerson, Carrie Cibulskis, Jia Liu, Joshua Armenia +95 more

Immunological and clinicopathological features predict HER2-positive breast cancer prognosis in the neoadjuvant NeoALTTO and CALGB 40601 randomized trials

Nature Communications(2023)10.1038/s41467-023-42635-2

N/A

0.434DataRank · unranked

17 citations

Aranzazu Fernández-Martínez, David Venet, Françoise Rothé, Katherine A. Hoadley, Joel S. Parker +17 more

Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502

npj Breast Cancer(2024)10.1038/s41523-024-00683-x

N/A

0.419DataRank · unranked

7 citations

Roberto Salgado, Oleksander Savenkov, Karla V. Ballman, Erica L. Mayer, Mark Jesus M. Magbanua +11 more

Defining the regulatory logic of breast cancer using single-cell epigenetic and transcriptome profiling

Cell Genomics(2025)10.1016/j.xgen.2025.100765

Top 45%

0.406DataRank

Top 45%11 citations

Susana García‐Recio, Aatish Thennavan, Kamila Wiśniewska, Raúl Méndez-Giráldez, Brooke Felsheim +5 more

Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.09.455691

Top 46%

0.395DataRank

Top 46%8 citations

Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy +13 more

Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal

UNC Libraries(2020)10.17615/42xt-ty92

N/A

0.312DataRank · unranked

7 citations

Ross L. Levine, Melissa A. Troester, Cleo Y. Lee, Kelly James Clark, Youngtae Jeong +12 more

Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer

UNC Libraries(2020)10.17615/jzdr-pp07

N/A

0.292DataRank · unranked

6 citations

Howard H. Yang, Cheng Fan, Jung S. Byun, Tara Taylor, Olufunmilayo I. Olopade +13 more

Stain SAN: simultaneous augmentation and normalization for histopathology images

Journal of Medical Imaging(2024)10.1117/1.jmi.11.4.044006

N/A

0.269DataRank · unranked

5 citations

Yao Li, Benjamin C. Calhoun, Aatish Thennavan, Lisa A. Carey, W. Fraser Symmans +4 more

Proteogenomics connects somatic mutations to signalling in breast cancer

UNC Libraries(2020)10.17615/mepw-5x28

N/A

0.269DataRank · unranked

5 citations

Mani, Kelly V. Ruggles, Michael A. Gillette, Karl R. Clauser, Pei Wang +31 more

Defining the Regulatory Logic of Breast Cancer Using Single-Cell Epigenetic and Transcriptome Profiling

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.13.598858

Top 61%

0.236DataRank

Top 61%3 citations

Susana García‐Recio, Aatish Thennavan, Kamila Wiśniewska, Raúl Méndez-Giráldez, Brooke Felsheim +5 more

Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102154

N/A

0.212DataRank · unranked

3 citations

Aranzazu Fernandez-Martinez, Tanmayi D. Vashist, Matthew V. Holt, LaTerrica Williams, Jonathan T. Lei +26 more

Integrative Proteogenomics and Forward Genetics Reveal a Novel Mitotic Vulnerability in Triple-Negative Breast Cancer

Cancer Discovery(2025)10.1158/2159-8290.cd-23-1173

N/A

0.208DataRank · unranked

3 citations

Shankha Satpathy, Karsten Krug, Jitendra K. Meena, Nivetha Ramesh Babu, Cheyenne Calderon +51 more

Receiver operating characteristic curves and confidence bands for support vector machines

UNC Libraries(2024)10.17615/azww-yq29

N/A

0.208DataRank · unranked

3 citations

Eric B. Laber, Samer S. El‐Kamary, Charles M. Perou, Fatma M. Shebl, Cheng Fan +3 more

Association of tumor infiltrating lymphocyte quantity with survival in patients (pts) with metastatic breast cancer (MBC) receiving microtubule-targeting agents: Post hoc analysis CALGB 40502 (Alliance).

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.1010

N/A

0.203DataRank · unranked

2 citations

Roberto Salgado, Oleksandr Savenkov, Karla V. Ballman, Mark Jesus M. Magbanua, Sherene Loi +11 more

Kinase Plasticity with Vandetanib Treatment Enhances Sensitivity to Tamoxifen in Estrogen Receptor Positive Breast Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.19.629395

N/A

0.174DataRank · unranked

2 citations

Rasha T. Kakati, Santiago Haase, Christine Thai, Attila Szénási, Elizabeth Brunk +10 more

Gene expression biomarkers differentiate overall survival of colorectal cancer upon targeted therapies

Research Square(2024)10.21203/rs.3.rs-4047331/v1

N/A

0.165DataRank · unranked

2 citations

Azam Yazdani, Raúl Méndez-Giráldez, Gianluigi Pillonetto, Esmat Samiei, Reza Hadi +10 more

Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Communications Biology(2022)10.1038/s42003-022-03769-z

N/A

0.165DataRank · unranked

2 citations

Lars Feuerbach, Chen Hong, David Mas-Ponte, Randi Istrup Pedersen, PCAWG Drivers and Functional Interpretation Group +1255 more

Genome-Wide Interaction Analysis of Menopausal Hormone Therapy Use and Breast Cancer Risk Among 62,370 Women

Research Square(2021)10.21203/rs.3.rs-532921/v1

Top 71%

0.126DataRank

Top 71%1 citations

Pooja Middha, Paul L. Auer, Joe Dennis, Alison M. Dunning, Qin Wang +75 more

An Analysis of the Sensitivity of Proteogenomic Mapping of Somatic Mutations and Novel Splicing Events in Cancer

UNC Libraries(2020)10.17615/rdzv-r921

Top 78%

0.104DataRank

Top 78%1 citations

Richard D. Smith, Robbert J.C. Slebos, Shisheng Sun, Zhen Zhang, Hui Zhang +33 more

Fibroblast Growth Factor Receptor Signaling Dramatically Accelerates Tumorigenesis and Enhances Oncoprotein Translation in the Mouse Mammary Tumor Virus-Wnt-1 Mouse Model of Breast Cancer

UNC Libraries(2020)10.17615/mp1b-n734

N/A

0DataRank · unranked

0 citations

Charles M. Perou, Jeffrey M. Rosen, Brian York, Susan G. Hilsenbeck, Chad J. Creighton +7 more

An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1

UNC Libraries(2020)10.17615/qy3p-zp42

N/A

0DataRank · unranked

0 citations

Richard K. Wilson, Katherine A. Hoadley, Gad Getz, Heidi S. Feiler, Jann N. Sarkaria +28 more

Pseudogenes transcribed in breast invasive carcinoma show subtype-specific expression and ceRNA potential

UNC Libraries(2020)10.17615/68b3-p023

N/A

0DataRank · unranked

0 citations

Jan F. Prins, Charles M. Perou, Jeanette Baran‐Gale, Praveen Sethupathy, Joshua D. Welch

Human epidermal growth factor receptor-2 and estrogen receptor expression, a demonstration project using the residual tissue respository of the Surveillance, Epidemiology, and End Results (SEER) program

UNC Libraries(2020)10.17615/29f0-zz17

N/A

0DataRank · unranked

0 citations

M. T. Goodman, Nilanjan Chatterjee, W. F. Anderson, R. K. Matsuno, Charles M. Perou +10 more

The Use of Bayesian Hierarchical Models for Adaptive Randomization in Biomarker-Driven Phase II Studies

UNC Libraries(2020)10.17615/8tqa-vs28

N/A

0DataRank · unranked

0 citations

Joseph G. Ibrahim, Charles M. Perou, Lisa A. Carey, P. Kelly Marcom, William T. Barry

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

UNC Libraries(2020)10.17615/twk7-x350

N/A

0DataRank · unranked

0 citations

Victor Weigman, Nicholas J. Wang, Vicente Valero, Aňa Lluch, Jane Fridlyand +22 more

An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer

UNC Libraries(2020)10.17615/zb8w-vx93

N/A

0DataRank · unranked

0 citations

Joel S. Parker, Grace O. Silva, Cheng Fan, Michael L. Gatza, Charles M. Perou

Differential Pathogenesis of Lung Adenocarcinoma Subtypes Involving Sequence Mutations, Copy Number, Chromosomal Instability, and Methylation

UNC Libraries(2020)10.17615/0bw4-4n26

N/A

0DataRank · unranked

0 citations

Alden M. Parsons, Philip S. Bernard, Leigh B. Thorne, C. Ryan Miller, William K. Funkhouser +12 more

c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression

UNC Libraries(2020)10.17615/dpd2-z189

N/A

0DataRank · unranked

0 citations

Carla L. Van Den Berg, Nancy D. Ebelt, Charles M. Perou, Michael A. Cantrell, Adam D. Pfefferle

The molecular basis of breast cancer pathological phenotypes

UNC Libraries(2020)10.17615/p1q8-ts12

N/A

0DataRank · unranked

0 citations

Kristin C. Jensen, Yunn‐Yi Chen, Gregor Krings, Frederic M. Waldman, Yujing J. Heng +24 more

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

UNC Libraries(2020)10.17615/dkm6-h153

N/A

0DataRank · unranked

0 citations

Adam D. Pfefferle, Benjamin T. Spike, J. Chuck Harrell, Jeffrey M. Rosen, Maria I. Torres‐Arzayus +7 more

MapSplice: Accurate mapping of RNA-seq reads for splice junction discovery

UNC Libraries(2020)10.17615/kqqa-r802

N/A

0DataRank · unranked

0 citations

Darshan Singh, James N. MacLeod, Piotr A. Mieczkowski, Zheng Zeng, Kai Wang +9 more

Integrated RNA and DNA sequencing improves mutation detection in low purity tumors

UNC Libraries(2020)10.17615/3rkd-y768

N/A

0DataRank · unranked

0 citations

Vonn Walter, Joel S. Parker, Melissa A. Troester, Peter S. Hammerman, Charles M. Perou +6 more

Epidemiology of basal-like breast cancer (Breast Cancer Research and Treatment DOI: 10.1007/s10549-007-9632-6)

UNC Libraries(2020)10.17615/2kpx-j447

N/A

0DataRank · unranked

0 citations

Susan Jackson, Chiu Kit Tse, Sarah J. Nyante, Charles M. Perou, Patricia G. Moorman +10 more

Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer

UNC Libraries(2020)10.17615/yge2-qn91

N/A

0DataRank · unranked

0 citations

Allison M. Deal, Sumit Rawal, David B. Darr, Carey K. Anders, William C. Zamboni +10 more

BlackOPs: increasing confidence in variant detection through mappability filtering

UNC Libraries(2020)10.17615/br5w-yv71

N/A

0DataRank · unranked

0 citations

D. Neil Hayes, Jan F. Prins, Charles M. Perou, Matthew G. Soloway, Matthew D. Wilkerson +4 more

MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11

UNC Libraries(2020)10.17615/bhpk-5y17

N/A

0DataRank · unranked

0 citations

Geoffrey L. Greene, Charles M. Perou, Yujia Wen, Seo Young Park, Ya-Fang Chang +14 more

A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis

UNC Libraries(2020)10.17615/4rey-fx73

N/A

0DataRank · unranked

0 citations

Sara Gutiérrez-Ángel, Christina Hartl, Annika L. Gable, Sun Y. Kim, Gregory J. Hannon +11 more

Integrated Analyses of microRNAs Demonstrate Their Widespread Influence on Gene Expression in High-Grade Serous Ovarian Carcinoma

UNC Libraries(2020)10.17615/hr2a-ez20

Top 100%

0DataRank

Top 100%0 citations

Richard A. Gibbs, Nikolaus Schultz, Chris Sander, Parminder K. Mankoo, Ying Du +14 more

Radiation-related genomic profile of papillary thyroid carcinoma after the Chernobyl accident

Science(2021)10.1126/science.abg2538

N/A

0DataRank · unranked

165 citations

Danielle M. Karyadi, Chip Stewart, Bogdanova Ti, Eric T. Dawson, Mia Steinberg +34 more

FOXA1 overexpression suppresses interferon signaling and immune response in cancer

Journal of Clinical Investigation(2021)10.1172/jci147025

N/A

0DataRank · unranked

90 citations

Liguo Wang, Ting Wei, Yu‐Tian Xiao, Haoyue Sheng, Hengchuan Su +24 more

Entinostat induces antitumor immune responses through immune editing of tumor neoantigens

Journal of Clinical Investigation(2021)10.1172/jci138560

N/A

0DataRank · unranked

83 citations

Mi Zhou, Bhavani Krishnan, Takanobu Utsumi, Ujjawal Manocha, Kyle G. Stewart +12 more

MultiK: an automated tool to determine optimal cluster numbers in single-cell RNA sequencing data

Genome biology(2021)10.1186/s13059-021-02445-5

N/A

0DataRank · unranked

49 citations

Aatish Thennavan, Joseph P. Garay, J. S. Marron, Charles M. Perou, Siyao Liu

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036

npj Breast Cancer(2021)10.1038/s41523-021-00258-0

N/A

0DataRank · unranked

24 citations

Timothy J. Stuhlmiller, Gaurav Mehta, Samantha M. Bevill, Daniel R. Goulet, José F. Olivares-Quintero +25 more

TP53 Pathway Function, Estrogen Receptor Status, and Breast Cancer Risk Factors in the Carolina Breast Cancer Study

Cancer Epidemiology Biomarkers & Prevention(2021)10.1158/1055-9965.epi-21-0661

N/A

0DataRank · unranked

9 citations

Mustapha Abubakar, Alina M. Hamilton, Kathleen Conway, Katherine A. Hoadley, Michael I. Love +5 more

Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation

UNC Libraries(2021)10.17615/bxh8-g735

N/A

0DataRank · unranked

3 citations

Yi‐Hua Liao, Xiang Zhang, Chad J. Creighton, Yi Li, Eric L. Chang +12 more

Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas

UNC Libraries(2021)10.17615/s799-wk91

N/A

0DataRank · unranked

1 citations

Lindsay A. Williams, J. Geradts, Andrew F. Olshan, K.A. Hoadley, Melissa A. Troester +3 more

Finding large average submatrices in high dimensional data

UNC Libraries(2021)10.17615/sfpp-6q61

N/A

0DataRank · unranked

1 citations

Andrey A. Shabalin, Charles M. Perou, Andrew B. Nobel, Victor Weigman

Reproductive risk factor associations with lobular and ductal carcinoma in the Carolina Breast Cancer Study

UNC Libraries(2021)10.17615/4vsf-t037

N/A

0DataRank · unranked

1 citations

M.E. Bell, J. Geradts, Charles M. Perou, Andrew F. Olshan, M.I. Love +5 more

DNA defects, epigenetics, and gene expression in cancer-adjacent breast: A study from the cancer genome atlas

UNC Libraries(2021)10.17615/4p83-f560

N/A

0DataRank · unranked

1 citations

Katherine A. Hoadley, A.G. Robertson, Melissa A. Troester, Ritinder Sandhu, M. Sheth +17 more

Gene-level germline contributions to clinical risk of recurrence scores in Black and White breast cancer patients

medRxiv(2021)10.1101/2021.03.19.21253983

N/A

0DataRank · unranked

3 citations

Montserrat García‐Closas, Andrew F. Olshan, Charles M. Perou, Melissa A. Troester, Michael I. Love +2 more

Chemotherapy coupled to macrophage inhibition leads to enhanced T and B cell infiltration and durable triple negative breast cancer regression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.22.432300

N/A

0DataRank · unranked

0 citations

Nigel Lee, Diego A. Pedroza, Igor Bado, Licheng Zhang, Sergio Aguirre +15 more

Rare Copy Number Variants (CNVs) and Breast Cancer Risk

Research Square(2021)10.21203/rs.3.rs-602209/v1

N/A

0DataRank · unranked

0 citations

Jonathan P. Tyrer, Logan C. Walker, Kyriaki Michailidou, Leila Dorling, Manjeet Bola +95 more

Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.16.448722

N/A

0DataRank · unranked

0 citations

Elena B. Kabotyanski, Elizabeth Villegas, Jonathan H. Shepherd, Deanna Acosta, Clark Hamor +11 more

Rare copy number variants (CNVs) and breast cancer risk

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.20.444828

N/A

0DataRank · unranked

0 citations

Jonathan P. Tyrer, Logan C. Walker, Kyriaki Michailidou, Leila Dorling, Manjeet K. Bolla +95 more

Genome-wide Interaction Analysis of Menopausal Hormone Therapy Use and Breast Cancer Risk among 62,370 Women

Research Square(2021)10.21203/rs.3.rs-532921/v2

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UNC Libraries(2021)10.17615/3f07-jr16

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UNC Libraries(2021)10.17615/3tpy-0m87

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UNC Libraries(2021)10.17615/44zm-xv81

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bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.07.499039

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Research Square(2022)10.21203/rs.3.rs-1221704/v1

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Research Square(2022)10.21203/rs.3.rs-1479039/v1

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Journal of Clinical Investigation(2023)10.1172/jci172503

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bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.28.559973

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bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.01.535159

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Data from PIK3CA and PIK3CB Inhibition Produce Synthetic Lethality when Combined with Estrogen Deprivation in Estrogen Receptor–Positive Breast Cancer

(2023)10.1158/0008-5472.c.6499523.v1

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Figshare(2023)10.1158/0008-5472.22378737.v1

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(2023)10.1158/0008-5472.c.6513885.v1

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(2023)10.1158/0008-5472.c.6500456

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(2023)10.1158/0008-5472.22378674

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(2023)10.1158/1078-0432.c.6519519.v1

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(2023)10.1158/0008-5472.c.6513992

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bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.14.544381

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UNC Libraries(2023)10.17615/414n-yp83

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The Journal of Pathology(2024)10.1002/path.6271

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UNC Libraries(2024)10.17615/dcbd-7h53

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UNC Libraries(2024)10.17615/41px-cd59

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bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.09.584084

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bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.586306

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bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.04.614143

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UNC Libraries(2024)10.17615/e69w-jc80

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UNC Libraries(2024)10.17615/nqjk-v350

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UNC Libraries(2024)10.17615/8e8s-xs13

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UNC Libraries(2024)10.17615/pg5w-dx64

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UNC Libraries(2024)10.17615/nbrq-z246

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Journal for ImmunoTherapy of Cancer(2025)10.1136/jitc-2024-010179

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PLoS Medicine(2025)10.1371/journal.pmed.1004647

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bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.30.651522

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UNC Libraries(2025)10.17615/0jnc-x739

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npj Breast Cancer(2025)10.1038/s41523-025-00804-0

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Bo Qin, Marc A. Emerson, Etienne X. Holder, Matthew R. Dunn, Shromona Sarkar +21 more

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medRxiv(2025)10.1101/2025.08.25.25334393

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UNC Libraries(2025)10.17615/7wtm-0322

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UNC Libraries(2025)10.17615/se9n-4867

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UNC Libraries(2025)10.17615/rbz3-7m15

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Scott Kopetz, Rashid, Naim U, Mark J. Ratain, Esmat Samiei, Federico Innocenti +18 more

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Nature Communications(2022)10.1038/s41467-022-32343-8

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Matthew G. Ewend, Michael Mullins, Chad Livasy, Heidi J. Hansen, Mary C. Mone +26 more

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A multivariable prognostic score to guide systemic therapy in early-stage HER2-positive breast cancer: a retrospective study with an external evaluation

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Biometrics(2020)10.1111/biom.13365

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UNC Libraries(2020)10.17615/kc1f-7b19

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Jodie M. Fleming, Erin L. Kirk, Charles M. Perou, Whitney R. Robinson, Monica D’Arcy +1 more

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UNC Libraries(2020)10.17615/vgd4-dp70

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UNC Libraries(2020)10.17615/awrf-kz95

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UNC Libraries(2020)10.17615/ebx5-w380

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UNC Libraries(2020)10.17615/6818-b214

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Richard K. Wilson, Marni B. Siegel, Katherine A. Hoadley, Krishna Kanchi, Xiaping He +10 more

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UNC Libraries(2020)10.17615/n3y7-sa69

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UNC Libraries(2020)10.17615/ycwx-4c45

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UNC Libraries(2020)10.17615/bd0j-6b91

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UNC Libraries(2020)10.17615/bgrr-9v25

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Anna Maria Storniolo, Vered Stearns, Vandana G. Abramson, Joel S. Parker, Catherine Van Poznak +19 more

Vimentin DNA methylation predicts survival in breast cancer

UNC Libraries(2020)10.17615/nsq3-am92

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UNC Libraries(2020)10.17615/9pmf-8y70

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UNC Libraries(2020)10.17615/np0d-4636

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0DataRank · unranked

0 citations

Manaswi Gupta, Anouk van Berkel, Jessica Marquard, Tobias Else, Ian T. Fiddes +95 more

Dietary Energy Balance Modulates Epithelial-to-Mesenchymal Transition and Tumor Progression in Murine Claudin-Low and Basal-like Mammary Tumor Models

UNC Libraries(2020)10.17615/5xas-3h25

N/A

0DataRank · unranked

0 citations

Lyuba Varticovski, Letícia Nogueira, Sarah M. Dunlap, Lucia J. Chiao, Stephen D. Hursting +2 more

Molecular Characterization of Human Breast Tumor Vascular Cells

UNC Libraries(2020)10.17615/9zgf-cq08

N/A

0DataRank · unranked

0 citations

Cheng Fan, Franco Gabrielli, Zhiyuan Hu, Charles M. Perou, Chad Livasy +7 more

Molecular Heterogeneity and Response to Neoadjuvant Human Epidermal Growth Factor Receptor 2 Targeting in CALGB 40601, a Randomized Phase III Trial of Paclitaxel Plus Trastuzumab With or Without Lapatinib

UNC Libraries(2020)10.17615/6adk-r027

N/A

0DataRank · unranked

0 citations

Carey K. Anders, Charles M. Perou, Ian E. Krop, Constance Cirrincione, Brandelyn N. Pitcher +13 more

Activating PIK3CA Mutations Induce an Epidermal Growth Factor Receptor (EGFR)/Extracellular Signal-regulated Kinase (ERK) Paracrine Signaling Axis in Basal-like Breast Cancer

UNC Libraries(2020)10.17615/jyfd-8k67

N/A

0DataRank · unranked

0 citations

Meghan M. Morrison, Rebecca S. Cook, Dana M. Brantley‐Sieders, D.C. Liebler, Joyce O’Shaughnessy +23 more

MAP3K4/CBP-Regulated H2B Acetylation Controls Epithelial-Mesenchymal Transition in Trophoblast Stem Cells

UNC Libraries(2020)10.17615/awxx-pc97

N/A

0DataRank · unranked

0 citations

Leping Li, Piotr A. Mieczkowski, Weichun Huang, Aleix Prat, Alicia A. Midland +7 more

Lung Squamous Cell Carcinoma mRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types

UNC Libraries(2020)10.17615/5tdz-sn55

N/A

0DataRank · unranked

0 citations

Philip S. Bernard, Alden M. Parsons, Kenneth L. Muldrew, Leigh B. Thorne, Mark A. Socinski +13 more

Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells

UNC Libraries(2020)10.17615/s3d9-3217

N/A

0DataRank · unranked

0 citations

Christopher Dravis, Geoffrey M. Wahl, J. Chuck Harrell, Claire Johns, Christy L. Trejo +3 more

MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion

UNC Libraries(2020)10.17615/y54w-sk07

N/A

0DataRank · unranked

0 citations

Olufunmilayo I. Olopade, Kathy Yee, Geoffrey L. Greene, Simo Huang, Huiping Liu +9 more

Differential methylation relative to breast cancer subtype and matched normal tissue reveals distinct patterns

UNC Libraries(2020)10.17615/ry0b-5156

N/A

0DataRank · unranked

0 citations

Sabrina A. Bardowell, Theresa Swift‐Scanlan, Jamie Crandell, Joel S. Parker, Charles M. Perou +1 more

Role of HGF in obesity-associated tumorigenesis: C3(1)-TAg mice as a model for human basal-like breast cancer

UNC Libraries(2020)10.17615/13c6-0405

N/A

0DataRank · unranked

0 citations

J. Justin Milner, David B. Darr, Alex J. Freemerman, Liza Makowski, Joseph A. Galanko +6 more

SigFuge: single gene clustering of RNA-seq reveals differential isoform usage among cancer samples

UNC Libraries(2020)10.17615/p1bn-vk90

N/A

0DataRank · unranked

0 citations

Christopher A. Maher, Matthew D. Wilkerson, Amy Johnson, Charles M. Perou, J. S. Marron +6 more

Phase II Study of Bortezomib and Pegylated Liposomal Doxorubicin in the Treatment of Metastatic Breast Cancer

UNC Libraries(2020)10.17615/wwde-9r73

N/A

0DataRank · unranked

0 citations

Frances A. Collichio, Philip S. Bernard, Robert Z. Orlowski, Inge J. Stijleman, Anastasia Ivanova +5 more

Pentraxin-3 is a PI3K signaling target that promotes stem cell–like traits in basal-like breast cancers

UNC Libraries(2020)10.17615/ymkd-4394

N/A

0DataRank · unranked

0 citations

Whitney S. Henry, Laetitia Fuhrmann, Alex Toker, Cheng Fan, Antoine E. Karnoub +9 more

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

UNC Libraries(2020)10.17615/s3ab-0w32

N/A

0DataRank · unranked

0 citations

Gordon B. Mills, Nilsa C. Ramirez, Andrew J. Mungall, Hailei Zhang, Nikolaus Schultz +95 more

Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

UNC Libraries(2020)10.17615/xk87-3a74

N/A

0DataRank · unranked

0 citations

Aleix Prat, Piyush B. Gupta, Adam Skibinski, Charles M. Perou, Theresa A. Proia +7 more

TBCRC 001: Randomized Phase II Study of Cetuximab in Combination With Carboplatin in Stage IV Triple-Negative Breast Cancer

UNC Libraries(2020)10.17615/yrss-qx89

N/A

0DataRank · unranked

0 citations

Charles M. Perou, Madlyn Ferraro, Mothaffar F. Rimawi, Wing‐Keung Chiu, Antonio C. Wolff +15 more

Prediction of Lung Cancer Histological Types by RT-qPCR Gene Expression in FFPE Specimens

UNC Libraries(2020)10.17615/nnne-sq26

N/A

0DataRank · unranked

0 citations

Jason Schallheim, Michele C. Hayward, Leigh B. Thorne, Xiaoying Yin, D. Neil Hayes +12 more

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p

UNC Libraries(2020)10.17615/dnrn-cx42

N/A

0DataRank · unranked

0 citations

Heide L. Ford, Austin E. Gillen, Carol A. Sartorius, Michelle A. Guney, Aik Choon Tan +7 more

Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome

UNC Libraries(2020)10.17615/9gqk-0s87

N/A

0DataRank · unranked

0 citations

Charles M. Perou, Phillippe Haas, Holger Dieterich, Markus Zuber, Rob Tibshirani +11 more

PREDICTION OF TOXICANT-SPECIFIC GENE EXPRESSION SIGNATURES FOLLOWING CHEMOTHERAPEUTIC TREATMENT OF BREAST CELL LINES

UNC Libraries(2020)10.17615/2988-c842

N/A

0DataRank · unranked

0 citations

Charles M. Perou, Melissa A. Troester, Katherine A. Hoadley, Joel S. Parker

Relationship Between Plasma Estradiol Levels and Estrogen-Responsive Gene Expression in Estrogen Receptor–Positive Breast Cancer in Postmenopausal Women

UNC Libraries(2020)10.17615/2dy4-8b47

N/A

0DataRank · unranked

0 citations

Anita K. Dunbier, H Anderson, Elizabeth Folkerd, Charles M. Perou, Roger A’Hern +9 more

SynthEx: a synthetic-normal-based DNA sequencing tool for copy number alteration detection and tumor heterogeneity profiling

UNC Libraries(2020)10.17615/wep6-xc29

N/A

0DataRank · unranked

0 citations

Lisle E. Mose, Charles M. Perou, Marni B. Siegel, Joel S. Parker, Mengjie Chen +2 more

SWISS MADE: Standardized WithIn Class Sum of Squares to Evaluate Methodologies and Dataset Elements

UNC Libraries(2020)10.17615/z3v8-ag63

N/A

0DataRank · unranked

0 citations

Jianying Li, Cheng Fan, D. Neil Hayes, Yuan Qi, Eric Bair +6 more