Seiko Ikezu

Also affiliated with Jacksonville College, Mayo Clinic in Florida

NeuroscienceBiochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.7Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

Alzheimer s & Dementia(2020)10.1002/alz.12089

Top 6%

3.7DataRank

Top 6%196 citations

Annina M. DeLeo, Manveen K. Sethi, Kayo Takamatsu-Yukawa, Zijian Yang, Jina Ko +14 more

Papers

Driven by 21 papers — median percentile 94. Top paper: “Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues”.

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

Alzheimer s & Dementia(2020)10.1002/alz.12089

Top 6%

3.7DataRank

Top 6%196 citations

Annina M. DeLeo, Manveen K. Sethi, Kayo Takamatsu-Yukawa, Zijian Yang, Jina Ko +14 more

Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo

Cell Reports(2024)10.1016/j.celrep.2024.115025

N/A

0.405DataRank · unranked

11 citations

Zhi Ruan, Bridgette Melvin, Ikshu Pandey, Seiko Ikezu, Tsuneya Ikezu +1 more

P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice

Molecular Neurodegeneration(2020)10.1186/s13024-020-00396-2

N/A

0DataRank · unranked

156 citations

Jean-Christophe Delpech, Srinidhi Venkatesan Kalavai, Alicia A. Van Enoo, Jianqiao Hu, Seiko Ikezu +2 more

Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons

Brain(2020)10.1093/brain/awaa376

N/A

0DataRank · unranked

281 citations

Dhruba Pathak, Srinidhi Venkatesan Kalavai, Asuka Yoshii-Kitahara, Satoshi Muraoka, Nemil Bhatt +12 more

Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities

Molecular Psychiatry(2020)10.1038/s41380-020-0671-2

N/A

0DataRank · unranked

90 citations

Hana Yeh, Jean-Christophe Delpech, Maya E. Woodbury, Alicia A. Van Enoo, Zhi Ruan +17 more

Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models

Acta Neuropathologica Communications(2020)10.1186/s40478-020-0890-4

N/A

0DataRank · unranked

32 citations

Kaitlin L. Ingraham Dixie, Lacin Koro, Takashi Watanabe, Kozo Kaibuchi, Tsuneya Ikezu +1 more

Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized APP mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.22.308015

N/A

0DataRank · unranked

4 citations

Jean-Christophe Delpech, Shawn Herron, Naotoshi Iwahara, Takashi Saito, Takaomi C. Saido +3 more

Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer’s disease mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.05.369728

N/A

0DataRank · unranked

2 citations

Mark P. Jedrychowski, Naotoshi Iwahara, Mohammad Abdullah, Kristen D. Onos, Kelly J. Keezer +6 more

Alzheimer’s disease brain-derived tau-containing extracellular vesicles: Pathobiology and GABAergic neuronal transmission

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.15.992719

N/A

0DataRank · unranked

1 citations

Dhruba Pathak, Srinidhi Venkatesan Kalavai, Asuka Yoshii-Kitahara, Satoshi Muraoka, Kayo Takamatsu-Yukawa +11 more

Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

Molecular Neurodegeneration(2021)10.1186/s13024-021-00440-9

N/A

0DataRank · unranked

239 citations

Jean-Christophe Delpech, Shawn Herron, Naotoshi Iwahara, Maria Ericsson, Takashi Saito +4 more

Proteomic Profiling of Extracellular Vesicles Separated from Plasma of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy

Aging and Disease(2021)10.14336/ad.2020.0908

N/A

0DataRank · unranked

30 citations

Annina M. DeLeo, Zijian Yang, Harutsugu Tatebe, Kayo Yukawa-Takamatsu, Seiko Ikezu +5 more

Enrichment of Phosphorylated Tau (Thr181) and Functionally Interacting Molecules in Chronic Traumatic Encephalopathy Brain-derived Extracellular Vesicles

Aging and Disease(2021)10.14336/ad.2020.1007

N/A

0DataRank · unranked

13 citations

Weiwei Lin, Kayo Takamatsu-Yukawa, Jianqiao Hu, Seiko Ikezu, Michael DeTure +4 more

Microglial WNT5A supports dendritic spines maturation and neuronal firing

Brain Behavior and Immunity(2022)10.1016/j.bbi.2022.11.003

N/A

0DataRank · unranked

22 citations

Maya E. Woodbury, Kaitlin L. Ingraham Dixie, Tsuneya Ikezu, Seiko Ikezu, Hana Yeh

Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia

Cell Reports(2022)10.1016/j.celrep.2022.110791

N/A

0DataRank · unranked

17 citations

Kayo Takamatsu-Yukawa, Yuzhi Wang, Margaret Ushman, Adam Labadorf, Maria Ericsson +3 more

Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease

Nature Neuroscience(2023)10.1038/s41593-023-01355-y

N/A

0DataRank · unranked

112 citations

Shawn Herron, Sebastian Silveira, Kilian L. Kleemann, Christian Gauthier, Dania Mallah +18 more

ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids

Science Advances(2023)10.1126/sciadv.adi3647

N/A

0DataRank · unranked

86 citations

Zhengrong Zhang, Nadia Sultana, Maria Ericsson, Yuka A. Martens, Min Sun +5 more

Development and characterization of in vitro inducible immortalization of a murine microglia cell line for high throughput studies

Scientific Reports(2025)10.1038/s41598-025-87543-1

N/A

0DataRank · unranked

2 citations

Matthew A. de Cruz, Yang You, Seiko Ikezu, Tsuneya Ikezu, Hana Yeh

Rapid and high-yield recovery of plasma-derived extracellular vesicles using modified chromatography with soluble protein depletion for biomarker discovery

Cell Communication and Signaling(2025)10.1186/s12964-025-02263-3

N/A

0DataRank · unranked

1 citations

Zhengrong Zhang, Samuel Cortes, Son Nguyen, Prakruthi Vadakattu, Bridgette Melvin +8 more

P2RX7 regulates tauopathy progression via tau and mitochondria loading in extracellular vesicles

Research Square(2025)10.21203/rs.3.rs-6771517/v1

N/A

0DataRank · unranked

2 citations

Victor Bodart‐Santos, Arun Reddy Ravula, Yang You, M. F. L. Abdullah, Zhi Ruan +15 more

Proteomic characterization of neuronal extracellular vesicle interactomes in Alzheimer’s disease mouse model through TurboID-based proximity labeling

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.22.684016

N/A

0DataRank · unranked

0 citations

Yunfei Chen, M. F. L. Abdullah, S. Nguyen, James McQuaker-Kajiwara, Bridgette Melvin +6 more

Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer’s Disease Patients: A Pilot Study

Cells(2020)10.3390/cells9091959

N/A

0DataRank · unranked

191 citations

Mark P. Jedrychowski, Kiran Yanamandra, Seiko Ikezu, Steven P. Gygi, Tsuneya Ikezu +1 more

Seiko Ikezu

Indexed papers

Top data-sharing exemplar

Papers