David R. Clemmons

University of North Carolina at Chapel Hill

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

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Indexed papers

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 41 papers. Top paper: “Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation”.

Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation

UNC Libraries(2020)10.17615/fr93-qc34

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0.104DataRank · unranked

1 citations

David R. Clemmons, Christine Wai, Gang Xi, Morris F. White

IGF-I and IGFBP-2 Stimulate AMPK Activation and Autophagy, Which Are Required for Osteoblast Differentiation

UNC Libraries(2020)10.17615/xfgg-v532

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6 citations

Gang Xi, Clifford J. Rosen, David R. Clemmons

Enhancement of the anabolic effects of growth hormone and insulin-like growth factor I by use of both agents simultaneously.

UNC Libraries(2020)10.17615/ynk8-tn78

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17 citations

Robert C. Baxter, David R. Clemmons, L E Underwood, S R Kupfer

Dietary components that regulate serum somatomedin-C concentrations in humans.

UNC Libraries(2020)10.17615/pbpq-7t42

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9 citations

W L Isley, L E Underwood, David R. Clemmons

Recruitment of Nox4 to a Plasma Membrane Scaffold Is Required for Localized Reactive Oxygen Species Generation and Sustained Src Activation in Response to Insulin-like Growth Factor-I

UNC Libraries(2020)10.17615/tve6-g829

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1 citations

Christine Wai, David R. Clemmons, Xin Chun Shen, Gang Xi

PDK1 Recruitment to the SHPS-1 Signaling Complex Enhances Insulin-like Growth Factor-I-stimulated AKT Activation and Vascular Smooth Muscle Cell Survival

UNC Libraries(2020)10.17615/g343-bc39

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1 citations

Xinchun Shen, David R. Clemmons, Gang Xi, Yashwanth Radhakrishnan

The Insulin-like Growth Factor-1 Binding Protein Acid-labile Subunit Alters Mesenchymal Stromal Cell Fate

UNC Libraries(2020)10.17615/v6am-w487

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Hayden Williams Courtland, Yuki Kawashima, Shoshana Yakar, Yinjgie Wu, David R. Clemmons +5 more

The Association between Integrin-associated Protein and SHPS-1 Regulates Insulin-like Growth Factor-I Receptor Signaling in Vascular Smooth Muscle Cells

UNC Libraries(2020)10.17615/dtz0-c230

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0 citations

David R. Clemmons, Laura A. Maile, Jane Badley-Clarke

The Coordinate Cellular Response to Insulin-like Growth Factor-I (IGF-I) and Insulin-like Growth Factor-binding Protein-2 (IGFBP-2) Is Regulated through Vimentin Binding to Receptor Tyrosine Phosphatase β (RPTPβ)

UNC Libraries(2020)10.17615/0bns-k592

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Christine Wai, Xinchun Shen, David R. Clemmons, Gang Xi

Identification of Novel SHPS-1-associated Proteins and Their Roles in Regulation of Insulin-like Growth Factor-dependent Responses in Vascular Smooth Muscle Cells

UNC Libraries(2020)10.17615/ymn3-d385

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Xinchun Shen, David R. Clemmons, Gang Xi, Yashwanth Radhakrishnan

IGF-1 and bone: New discoveries from mouse models

UNC Libraries(2020)10.17615/qmej-n841

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David R. Clemmons, Shoshana Yakar, Hayden‐William Courtland

Role of SHPS-1 in the Regulation of Insulin-like Growth Factor I-stimulated Shc and Mitogen-activated Protein Kinase Activation in Vascular Smooth Muscle Cells

UNC Libraries(2020)10.17615/9k89-r457

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Ling Yan, Jane Badley-Clarke, David R. Clemmons, Jaroslava Lieskovská, Laura A. Maile

Insulin-like Growth Factor-I Stimulates Shc-dependent Phosphatidylinositol 3-Kinase Activation via Grb2-associated p85 in Vascular Smooth Muscle Cells

UNC Libraries(2020)10.17615/qc8t-2f77

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0 citations

Yashwanth Radhakrishnan, Ling Yan, Laura A. Maile, Lee M. Graves, David R. Clemmons

Metabolic Actions of Insulin-Like Growth Factor-I in Normal Physiology and Diabetes

UNC Libraries(2020)10.17615/kb8m-r916

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0 citations

David R. Clemmons

An essential role for the association of CD47 to SHPS-1 in skeletal remodeling

UNC Libraries(2020)10.17615/9p88-ag18

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Clifford J. Rosen, Victoria DeMambro, Ariel W. Aday, Laura A. Maile, Wesley G. Beamer +3 more

p66 shc Inhibits Insulin-like Growth Factor-I Signaling via Direct Binding to Src through Its Polyproline and Src Homology 2 Domains, Resulting in Impairment of Src Kinase Activation

UNC Libraries(2020)10.17615/xtjy-wt37

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0 citations

Xinchun Shen, Gang Xi, David R. Clemmons

Oxidized LDL and Fructosamine Associated with Severity of Coronary Artery Atherosclerosis in Insulin Resistant Pigs Fed a High Fat/High NaCl Diet

UNC Libraries(2020)10.17615/tqtp-4a79

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0 citations

Timothy C. Nichols, Jing Yu, Dwight A. Bellinger, Diana L. Lam, Elizabeth P. Merricks +4 more

Identification of Compounds That Inhibit IGF-I Signaling in Hyperglycemia

UNC Libraries(2020)10.17615/pa7h-5t26

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0 citations

Umadevi Veluvolu, Byron E. Capps, Lee Allen, Michael L. Rowland, David R. Clemmons +2 more

IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation: IRS-1 SCAFFOLD FOR IGF-I/IGFBP-2 SIGNALING IN OB DIFFERENTIATION

UNC Libraries(2020)10.17615/41m0-2r47

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0 citations

Gang Xi, Clifford J. Rosen, David R. Clemmons, Xinchun Shen

Erratum: Insulin-like growth factor-binding protein-2 is required for osteoclast differentiation

UNC Libraries(2020)10.17615/x96c-3c09

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Christine Wai, Laura A. Maile, Clifford J. Rosen, Masanobu Kawai, Victoria DeMambro +2 more

Insulin-like Growth Factor-I-stimulated Insulin Receptor Substrate-1 Negatively Regulates Src Homology 2 Domain-containing Protein-tyrosine Phosphatase Substrate-1 Function in Vascular Smooth Muscle Cells

UNC Libraries(2020)10.17615/114k-d729

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0 citations

David R. Clemmons, Yashwanth Radhakrishnan, Walker H. Busby, Xinchun Shen, Laura A. Maile

Insulin-like growth factors (IGF) in muscle development. Expression of IGF-I, the IGF-I receptor, and an IGF binding protein during myoblast differentiation.

UNC Libraries(2021)10.17615/cfd9-gq61

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20 citations

David R. Clemmons, R H McCusker, R Lajara, Peter Rotwein, S E Tollefsen

Substitutions for Hydrophobic Amino Acids in the N-terminal Domains of IGFBP-3 and -5 Markedly Reduce IGF-I Binding and Alter Their Biologic Actions

UNC Libraries(2021)10.17615/0x0z-p784

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12 citations

Walker H. Busby, David R. Clemmons, Uwe Andag, Yumi Imai, Jane B. Clarke +1 more

Substitution of Specific Amino Acids in Insulin-like Growth Factor (IGF) Binding Protein 5 Alters Heparin Binding and Its Change in Affinity for IGF-I in Response to Heparin

UNC Libraries(2021)10.17615/m2mn-7292

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7 citations

Jane Clarke, Alex Parker, Taek‐Jeong Nam, Walker Busby, David R. Clemmons +1 more

The Role of Src Kinase in Insulin-like Growth Factor-dependent Mitogenic Signaling in Vascular Smooth Muscle Cells

UNC Libraries(2021)10.17615/n0ds-yf62

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1 citations

Jane Badley-Clarke, Jaroslava Lieskovská, Ling Yan, David R. Clemmons

Tubular hypertrophy due to work load induced by furosemide is associated with increases of IGF-1 and IGFBP-1

UNC Libraries(2021)10.17615/2emn-ja46

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1 citations

Manjeri A. Venkatachalam, David R. Clemmons, Haruo Nogami, Shuzo Kobayashi, Arun K. Roy

Transcription Factor AP-2 Regulates Human Insulin-like Growth Factor Binding Protein-5 Gene Expression

UNC Libraries(2021)10.17615/gfw3-rd62

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13 citations

David R. Clemmons, Cunming Duan

Insulin-like Growth Factor-I (IGF-I) Regulates IGF-binding Protein-5 Synthesis through Transcriptional Activation of the Gene in Aortic Smooth Muscle Cells

UNC Libraries(2021)10.17615/g544-p276

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12 citations

Tracy Prevette, Scott B. Hawes, Cunming Duan, David R. Clemmons

Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I

UNC Libraries(2021)10.17615/c4re-w318

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6 citations

Cecilia Camacho‐Hübner, J. Iwan Jones, A Gockerman, Walker H. Busby, David R. Clemmons

Differential Expression and Biological Effects of Insulin-like Growth Factor-binding Protein-4 and -5 in Vascular Smooth Muscle Cells

UNC Libraries(2021)10.17615/s6rr-hq18

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5 citations

David R. Clemmons, Cunming Duan

Blocking ligand occupancy of the V 3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

UNC Libraries(2021)10.17615/0hq5-tx66

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3 citations

David R. Clemmons, Bo Zheng

Tissue Transglutaminase Facilitates the Polymerization of Insulin-like Growth Factor-binding Protein-1 (IGFBP-1) and Leads to Loss of IGFBP-1's Ability to Inhibit Insulin-like Growth Factor-I-stimulated Protein Synthesis

UNC Libraries(2021)10.17615/rj1e-1c94

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2 citations

Walker H. Busby, Keiji Sakai, Jane B. Clarke, David R. Clemmons

The Effect of Extracellular Matrix Proteins on Porcine Smooth Muscle Cell Insulin-like Growth Factor (IGF) Binding Protein-5 Synthesis and Responsiveness to IGF-I

UNC Libraries(2021)10.17615/skah-3e78

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1 citations

Bo Zheng, David R. Clemmons, Cumming Duan

A Monoclonal Antibody Against V 3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs

UNC Libraries(2021)10.17615/etjk-0n67

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0 citations

Laura A. Maile, Timothy C. Nichols, Walker H. Busby, Dwight A. Bellinger, Umadevi Veluvolu +3 more

Identification of the sites of phosphorylation in insulin-like growth factor binding protein-1 : regulation of its affinity by phosphorylation of serine 101

UNC Libraries(2021)10.17615/3cwk-5m25

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0 citations

Christine Smith, Nancee Kimack, J. H. Jones, Gabriëla Wright, Walker Busby +1 more

Regulation of Insulin-like Growth Factor I Receptor Dephosphorylation by SHPS-1 and the Tyrosine Phosphatase SHP-2

UNC Libraries(2021)10.17615/n31z-0v68

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0 citations

Laura A. Maile, David R. Clemmons

Binding of Insulin-like Growth Factor (IGF)–Binding Protein-5 to Smooth-Muscle Cell Extracellular Matrix Is a Major Determinant of the Cellular Response to IGF-I

UNC Libraries(2021)10.17615/6hnv-eg46

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0 citations

Walker H. Busby, David R. Clemmons, Alex Parker, Catherine Rees, Jane Clarke

Insulin-like Growth Factor I Increases α V β 3 Affinity by Increasing the Amount of Integrin-associated Protein That Is Associated with Non-raft Domains of the Cellular Membrane

UNC Libraries(2021)10.17615/f147-3r56

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0 citations

Yumi Imai, David R. Clemmons, Jane B. Clarke, Laura A. Maile

Identification of the Extracellular Matrix Binding Sites for Insulin-like Growth Factor-binding Protein 5

UNC Libraries(2021)10.17615/c05p-d575

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Alex Parker, Jane B. Clarke, Walker H. Busby, David R. Clemmons

Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice

Endocrinology(2020)10.1210/endocr/bqz007

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21 citations

Victoria DeMambro, Susan D’Costa, Shalier K. Xia, Zachary Cox, Clifford J. Rosen +2 more

Role of IGF-binding proteins in regulating IGF responses to changes in metabolism

UNC Libraries(2025)10.17615/n5fk-7b71

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0 citations

David R. Clemmons