Riekelt H. Houtkooper

Also affiliated with Amsterdam Neuroscience, Amsterdam University Medical Centers, Amsterdam University of Applied Sciences, University of Amsterdam

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 28 papers. Top paper: “Nutritional ketosis improves exercise metabolism in patients with very long‐chain acyl‐CoA dehydrogenase deficiency”.

Nutritional ketosis improves exercise metabolism in patients with very long‐chain acyl‐CoA dehydrogenase deficiency

Journal of Inherited Metabolic Disease(2020)10.1002/jimd.12217

N/A

1.4DataRank · unranked

39 citations

Gepke Visser, Kieran Clarke, Sacha Ferdinandusse, Ferdinand H. de Haan, Riekelt H. Houtkooper +15 more

ARDD 2020: from aging mechanisms to interventions

Aging(2020)10.18632/aging.202454

N/A

0.609DataRank · unranked

57 citations

Kotb Abdelmohsen, Pénélope A. Andreux, Ieva Bagdonaite, Nir Barzilai, Søren Brunak +61 more

A conserved complex lipid signature marks human muscle aging and responds to short-term exercise

Nature Aging(2024)10.1038/s43587-024-00595-2

N/A

0.568DataRank · unranked

43 citations

Marte Molenaars, Katharina Herzog, Lotte Grevendonk, Carlijn M. E. Remie, Martin A. T. Vervaart +19 more

Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy

Journal of Magnetic Resonance Imaging(2021)10.1002/jmri.27531

N/A

0.425DataRank · unranked

16 citations

S. Matthijs Boekholdt, Dylan K. de Vries, Yolan J. Reckman, Emile S. Farag, Paul de Heer +14 more

High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan

Cell Reports(2024)10.1016/j.celrep.2024.114836

N/A

0.312DataRank · unranked

7 citations

Gaby El Alam, Yunyun Zhu, Weisha Li, Jonathan Sulc, Xiaoxu Li +12 more

Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes

iScience(2025)10.1016/j.isci.2025.112880

N/A

0.165DataRank · unranked

2 citations

Marte Molenaars, Rashmi Kamble, Weisha Li, Bauke V. Schomakers, Adrie Dane +8 more

Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF‐16‐induced longevity

Aging Cell(2021)10.1111/acel.13381

N/A

0DataRank · unranked

22 citations

Simone Denis, Rashmi Kamble, Marte Molenaars, Michael Petr, Bauke V. Schomakers +9 more

Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity

Ageing Research Reviews(2022)10.1016/j.arr.2022.101621

N/A

0DataRank · unranked

69 citations

Yasmine J. Liu, Man Hu, Brian J. Morris, Bradley J. Willcox, Timothy A. Donlon +3 more

AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity

Blood Advances(2022)10.1182/bloodadvances.2022007383

N/A

0DataRank · unranked

20 citations

Guus de Wilde, Gerarda H. Khan, Timothy C. Ashby, John D. Shaughnessy, Fenghuang Zhan +6 more

Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4

Cell Reports(2022)10.1016/j.celrep.2022.111928

N/A

0DataRank · unranked

20 citations

Marte Molenaars, Bauke V. Schomakers, Arwen W. Gao, Rashmi Kamble, Aldo Jongejan +6 more

Stimulating the sir2–spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome

Disease Models & Mechanisms(2022)10.1242/dmm.049279

N/A

0DataRank · unranked

11 citations

Rubén Zapata‐Pérez, Kristin Richardson, Frédéric M. Vaz, Riekelt H. Houtkooper, Robert Wessells +1 more

A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways

Cell Metabolism(2020)10.1016/j.cmet.2020.01.011

N/A

0DataRank · unranked

129 citations

Georges E. Janssens, Evan G. Williams, Aldo Jongejan, Jiayi Lan, Sylvie Rabot +13 more

Stimulating the sir2-pgc-1ɑ axis rescues exercise capacity and mitochondrial respiration in Drosophila tafazzin mutants

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.06.475267

N/A

0DataRank · unranked

0 citations

Rubén Zapata‐Pérez, Riekelt H. Houtkooper, Robert Wessells, Deena Damschroder

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

Nature Communications(2023)10.1038/s41467-023-38410-y

N/A

0DataRank · unranked

41 citations

Esther García-Domínguez, Rebecca L. McIntyre, José Luis López-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez +23 more

ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH

Journal of Hepatology(2024)10.1016/j.jhep.2024.08.009

N/A

0DataRank · unranked

31 citations

Masaki Kimura, Xiaoxu Li, Jonathan Sulc, Qi Wang, Sandra Rodríguez-López +11 more

CIAO1 and MMS19 deficiency: A lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders

Genetics in Medicine(2024)10.1016/j.gim.2024.101104

N/A

0DataRank · unranked

13 citations

Maja Tarailo‐Graovac, René Leen, Rutger Meinsma, Solenne Correard, Judith Jansen-Meijer +38 more

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells

Scientific Reports(2024)10.1038/s41598-024-62262-1

N/A

0DataRank · unranked

8 citations

Tyler Ralph-Epps, Michael W. Schmidtke, Pablo Lazcano, Simone Denis, Maria Balazova +8 more

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.03.578755

N/A

0DataRank · unranked

2 citations

Tyler Ralph-Epps, Michael W. Schmidtke, Pablo Lazcano, Simone Denis, Maria Balazova +7 more

High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.15.575638

N/A

0DataRank · unranked

1 citations

Gaby El Alam, Yunyun Zhu, Weisha Li, Elena Katsyuba, Jonathan Sulc +12 more

Immuno-metabolic stress responses control longevity from mitochondrial translation inhibition in C. elegans

Nature Communications(2025)10.1038/s41467-025-61433-6

N/A

0DataRank · unranked

4 citations

Marte Molenaars, Yorrick Jaspers, Bauke V. Schomakers, Michel van Weeghel, Amber Bakker +7 more

Genetic mapping of lifespan and mitochondrial stress response in C. elegans

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.26.661693

N/A

0DataRank · unranked

0 citations

Weisha Li, Arwen W. Gao, Yunyun Zhu, Elena Katsyuba, Katherine A. Overmyer +11 more

Genetic mapping of lifespan and mitochondrial stress response in C. elegans

Research Square(2025)10.21203/rs.3.rs-7093535/v1

N/A

0DataRank · unranked

0 citations

Xiaoxu Li, Weisha Li, Arwen W. Gao, Yunyun Zhu, Elena Katsyuba +11 more

Meeting Report: Aging Research and Drug Discovery

Aging(2022)10.18632/aging.203859

N/A

0DataRank · unranked

6 citations

Maria Thaysen, Suzanne Angeli, Adam Antebi, Nir Barzilai, Joseph A. Baur +73 more

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

Nature Communications(2020)10.1038/s41467-020-15995-2

N/A

0DataRank · unranked

105 citations

Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke van Bergen +27 more

Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

The Journal of Cell Biology(2020)10.1083/jcb.201907067

N/A

0DataRank · unranked

50 citations

Rebecca L. McIntyre, Georges E. Janssens, Evan G. Williams, Jiayi Lan, Michel van Weeghel +9 more

The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators

Cell Reports(2020)10.1016/j.celrep.2020.108203

N/A

0DataRank · unranked

43 citations

Pooja Jha, Riekelt H. Houtkooper, Robert W. Williams, Xu Wang, Johan Auwerx +1 more

Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF-16-induced longevity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.24.219584

N/A

0DataRank · unranked

3 citations

Simone Denis, Rashmi Kamble, Michael Petr, Bauke V. Schomakers, Aldo Jongejan +4 more

Biological Age Prediction From Wearable Device Movement Data Identifies Nutritional and Pharmacological Interventions for Healthy Aging

Frontiers in Aging(2021)10.3389/fragi.2021.708680

N/A

0DataRank · unranked

23 citations

Mizanur Rahman, Siva A. Vanapalli, Riekelt H. Houtkooper, Georges E. Janssens, Rebecca L. McIntyre