Tony Velkov

Also affiliated with Australian Regenerative Medicine Institute, Monash University

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 35 papers. Top paper: “The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study”.

The Killing Mechanism of Teixobactin against Methicillin-Resistant Staphylococcus aureus: an Untargeted Metabolomics Study

mSystems(2020)10.1128/msystems.00077-20

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54 citations

John A. Karas, Elena K. Schneider‐Futschik, Fan Chen, James Swarbrick, Olivia K. A. Paulin +6 more

Lipid A profiling and metabolomics analysis of paired polymyxin-susceptible and -resistant MDR Klebsiella pneumoniae clinical isolates from the same patients before and after colistin treatment

Journal of Antimicrobial Chemotherapy(2020)10.1093/jac/dkaa245

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33 citations

Irene Galani, Mei‐Ling Han, Ilias Karaiskos, Darren J. Creek, Yan Zhu +5 more

Molecular dynamics simulations informed by membrane lipidomics reveal the structure–interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii

Journal of Antimicrobial Chemotherapy(2020)10.1093/jac/dkaa376

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50 citations

Kai Yang, Bing Yuan, Mei‐Ling Han, Yan Zhu, Kade D. Roberts +9 more

Polymyxin Triple Combinations against Polymyxin-Resistant, Multidrug-Resistant, KPC-Producing Klebsiella pneumoniae

Antimicrobial Agents and Chemotherapy(2020)10.1128/aac.00246-20

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21 citations

Irene Galani, Heidi H. Yu, Jiping Wang, Ke Chen, Hasini Wickremasinghe +9 more

Pan-transcriptomic analysis identified common differentially expressed genes of Acinetobacter baumannii in response to polymyxin treatments

Molecular Omics(2020)10.1039/d0mo00015a

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19 citations

Su Mon Aye, Maizbha Uddin Ahmed, Mei‐Ling Han, Chen Li, Jiangning Song +7 more

Simulations of octapeptin–outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.014856

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18 citations

Kai Yang, Bing Yuan, Bin Gong, Lin Wan, Nitin A. Patil +7 more

Genome-Scale Metabolic Modeling Reveals Metabolic Alterations of Multidrug-Resistant Acinetobacter baumannii in a Murine Bloodstream Infection Model

Microorganisms(2020)10.3390/microorganisms8111793

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30 citations

Yan Zhu, Jiru Han, Yu-Wei Lin, Michael Aichem, Jiping Wang +5 more

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

UNC Libraries(2020)10.17615/ckx5-4h52

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0 citations

Darren J. Creek, Jiangning Song, Jian Li, Anthony W. Purcell, Matthew D. Johnson +9 more

Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are we there yet?

UNC Libraries(2020)10.17615/wgag-ft94

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0 citations

Roger L. Nation, Alan Forrest, Tony Velkov, Brian T. Tsuji, Thien B. Tran +2 more

Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

UNC Libraries(2020)10.17615/hw93-gy10

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0 citations

Darren J. Creek, Jian Li, Tony Velkov, Mohd Hafidz Mahamad Maifiah, Brian T. Tsuji +2 more

Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane

Computational and Structural Biotechnology Journal(2021)10.1016/j.csbj.2021.06.051

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27 citations

Yuliang Sun, Kai Yang, Bing Yuan, Tony Velkov, Lushan Wang +2 more

Clinically Relevant Concentrations of Polymyxin B and Meropenem Synergistically Kill Multidrug-Resistant Pseudomonas aeruginosa and Minimize Biofilm Formation

Antibiotics(2021)10.3390/antibiotics10040405

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24 citations

Heidi H. Yu, Mohammad Abul Kalam Azad, Jinxin Zhao, Phillip J. Bergen, Tony Velkov +4 more

A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii

Chemical Science(2021)10.1039/d1sc03460j

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21 citations

Nitin A. Patil, Mohammad Abul Kalam Azad, Hasini Wickremasinghe, Heidi H. Yu, Jinxin Zhao +14 more

Polymyxins for the treatment of lower respiratory tract infections: lessons learned from the integration of clinical pharmacokinetic studies and clinical outcomes

International Journal of Antimicrobial Agents(2021)10.1016/j.ijantimicag.2021.106328

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15 citations

Estefany Garcia, Qi Zhou, Alan Forrest, Keith S. Kaye, Jian Li +3 more

In vitro evaluation of drug delivery behavior for inhalable amorphous nanoparticle formulations in a human lung epithelial cell model

International Journal of Pharmaceutics(2021)10.1016/j.ijpharm.2021.120211

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12 citations

Maizbha Uddin Ahmed, Chune Zhu, Shihui Yu, Weisan Pan, Tony Velkov +3 more

A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

Nature Communications(2022)10.1038/s41467-022-29234-3

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149 citations

Yan Zhu, Mohammad Abul Kalam Azad, Mei‐Ling Han, Jiping Wang, Lynn Wang +19 more

Comparative metabolomics revealed key pathways associated with the synergistic killing of multidrug-resistant Klebsiella pneumoniae by a bacteriophage-polymyxin combination

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2021.12.039

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25 citations

Sue C. Nang, Yu‐Wei Lin, Yan Zhu, Heidi H. Yu, Hasini Wickremasinghe +11 more

Correlative proteomics identify the key roles of stress tolerance strategies in Acinetobacter baumannii in response to polymyxin and human macrophages

PLoS Pathogens(2022)10.1371/journal.ppat.1010308

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19 citations

Mohammad Abul Kalam Azad, Mei‐Ling Han, Yan Zhu, Cheng Huang, Ralf B. Schittenhelm +6 more

Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa

Journal of Biomedical Science(2022)10.1186/s12929-022-00874-3

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17 citations

Yan Zhu, Brian T. Tsuji, Darren J. Creek, Tony Velkov, Jian Li +1 more

Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity

Cellular and Molecular Life Sciences(2022)10.1007/s00018-022-04316-z

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15 citations

Mohammad Abul Kalam Azad, Julie Moreau, Yan Zhu, Xukai Jiang, Mary A. Tonta +12 more

Polymyxin dose tunes the evolutionary dynamics of resistance in multidrug-resistant Acinetobacter baumannii

Clinical Microbiology and Infection(2022)10.1016/j.cmi.2022.02.043

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13 citations

Yan Zhu, Yu‐Wei Lin, Heidi H. Yu, Hasini Wickremasinghe, Jiru Han +4 more

Polymyxin Induces Significant Transcriptomic Perturbations of Cellular Signalling Networks in Human Lung Epithelial Cells

Antibiotics(2022)10.3390/antibiotics11030307

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2 citations

Mohammad Abul Kalam Azad, Maizbha Uddin Ahmed, Yan Zhu, Jiangning Song, Fanfan Zhou +5 more

Diversified repertoire of phage resistance in Klebsiella pneumoniae and bidirectional steering effects impacting antibiotic susceptibility

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.14.516531

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1 citations

Jing Lü, Heidi H. Yu, Hasini Wickremasinghe, Mohammad Abul Kalam Azad, Mei‐Ling Han +13 more

Comparative Proteomics of Outer Membrane Vesicles from Polymyxin-Susceptible and Extremely Drug-Resistant Klebsiella pneumoniae

mSphere(2023)10.1128/msphere.00537-22

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30 citations

Raad Jasim, Hakan Gocol, Mark A. Baker, Varsha J. Thombare, James Ziogas +5 more

Lipid A Modification and Metabolic Adaptation in Polymyxin-Resistant, New Delhi Metallo-β-Lactamase–Producing Klebsiella pneumoniae

Microbiology Spectrum(2023)10.1128/spectrum.00852-23

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13 citations

Mei‐Ling Han, Heidi H. Yu, Phillip J. Bergen, Yiyun Liu, Jinxin Zhao +7 more

High-level nitrofurantoin resistance in a clinical isolate of Klebsiella pneumoniae: a comparative genomics and metabolomics analysis

mSystems(2023)10.1128/msystems.00972-23

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13 citations

Zetao Sun, Jane Hawkey, Rafah Allobawi, Louise M. Judd, Vincenzo Carbone +8 more

Integrated Transcriptomic and Metabolomic Mapping Reveals the Mechanism of Action of Ceftazidime/Avibactam against Pan-Drug-Resistant Klebsiella pneumoniae

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00264

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8 citations

Rafah Allobawi, Jinxin Zhao, Heidi H. Yu, Stephanie L. Neville, Jonathan J. Wilksch +7 more

Proof‐of‐concept for incorporating mechanistic insights from multi‐omics analyses of polymyxin B in combination with chloramphenicol against Klebsiella pneumoniae

CPT Pharmacometrics & Systems Pharmacology(2023)10.1002/psp4.12923

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6 citations

Nusaibah Abdul Rahim, Rajnikant Sharma, Colin G. Cess, Stacey D. Finley, Phillip J. Bergen +4 more

Model-informed dose optimisation of polymyxin-rifampicin combination therapy against multidrug-resistant Acinetobacter baumannii

International Journal of Antimicrobial Agents(2023)10.1016/j.ijantimicag.2023.106902

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3 citations

Yan Zhu, Mei‐Ling Han, Jing Lü, Heidi H. Yu, Hasini Wickremasinghe +7 more

Phage resistance in Klebsiella pneumoniae and bidirectional effects impacting antibiotic susceptibility

Clinical Microbiology and Infection(2024)10.1016/j.cmi.2024.03.015

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26 citations

Jing Lü, Heidi H. Yu, Hasini Wickremasinghe, Mohammad Abul Kalam Azad, Mei‐Ling Han +13 more

Arginine catabolism is essential to polymyxin dependence in Acinetobacter baumannii

Cell Reports(2024)10.1016/j.celrep.2024.114410

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13 citations

Yasser Alsaadi, Jinxin Zhao, Yan Zhu, Jing Lu, Xukai Jiang +17 more

PhageGE: an interactive web platform for exploratory analysis and visualization of bacteriophage genomes

GigaScience(2024)10.1093/gigascience/giae074

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8 citations

Jiru Han, Yu‐Wei Lin, Yan Zhu, Michael Aichem, Dimitar Garkov +9 more

Metabolic profiling unveils enhanced antibacterial synergy of polymyxin B and teixobactin against multi-drug resistant Acinetobacter baumannii

Scientific Reports(2024)10.1038/s41598-024-78769-6

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6 citations

Zhisen Kang, Stephanie L. Neville, Rafah Allobawi, Varsha Thrombare, Augustine Jing Jie Koh +9 more

Transcriptomic interplay between Acinetobacter baumannii , human macrophage and polymyxin

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.23.576770

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0 citations

Mohammad Abul Kalam Azad, Yan Zhu, Mei‐Ling Han, Qi Zhou, Tony Velkov +3 more

A novel role for colistin as an efflux pump inhibitor in multidrug-resistant Klebsiella pneumoniae

Scientific Reports(2025)10.1038/s41598-025-18206-4

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4 citations

Shekhar Yeshwante, Ngoc Minh Bui, Vincenzo Carbone, Leslie M. Hicks, Bruce E. Blough +3 more