Rían W. Manville

Also affiliated with BioElectronics (United States)

Biochemistry, Genetics and Molecular BiologyNeuroscienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “Conifer metabolite pisiferic acid restores activity in human Kv1.2 potassium channels carrying pathogenic sequence variants”.

Conifer metabolite pisiferic acid restores activity in human Kv1.2 potassium channels carrying pathogenic sequence variants

iScience(2025)10.1016/j.isci.2025.113283

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0.208DataRank · unranked

3 citations

Richard Sidlow, Geoffrey W. Abbott, Rían W. Manville

Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine

Journal of Pharmacology and Experimental Therapeutics(2020)10.1124/jpet.119.264507

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22 citations

Geoffrey W. Abbott, Rían W. Manville

Potassium channels act as chemosensors for solute transporters

Communications Biology(2020)10.1038/s42003-020-0820-9

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16 citations

Geoffrey W. Abbott, Rían W. Manville

TOK channels use the two gates in classical K + channels to achieve outward rectification

The FASEB Journal(2020)10.1096/fj.202000545r

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9 citations

Zoe A. McCrossan, Rían W. Manville, M. Oana Popa, Luis G. Cuello, Steven A. Goldstein +1 more

Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly

Arteriosclerosis Thrombosis and Vascular Biology(2020)10.1161/atvbaha.120.313997

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35 citations

Rían W. Manville, Katie Hayes, Morten B. Thomsen, Geoffrey W. Abbott, Thomas A. Jepps +1 more

The Amyloid Precursor Protein C99 Fragment Modulates Voltage-Gated Potassium Channels.

Cellular Physiology and Biochemistry(2021)10.33594/000000397

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19 citations

Geoffrey W. Abbott, Rían W. Manville

KCNQ and KCNE Isoform-Dependent Pharmacology Rationalizes Native American Dual Use of Specific Plants as Both Analgesics and Gastrointestinal Therapeutics

Frontiers in Physiology(2021)10.3389/fphys.2021.777057

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17 citations

Kaitlyn E. Redford, Ryan F. Yoshimura, Rían W. Manville, Luiz Moreira, Kevin Tran +5 more

Activation of SGK1.1 Upregulates the M-current in the Presence of Epilepsy Mutations

Frontiers in Molecular Neuroscience(2021)10.3389/fnmol.2021.798261

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3 citations

Rían W. Manville, Belinda Rivero-Pérez, David Bartolomé‐Martín, Diego Álvarez de la Rosa, Geoffrey W. Abbott +2 more

Activation of SGK1.1 up-regulates the M-current in the presence of epilepsy mutations

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.19.464941

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0 citations

Rían W. Manville, Belinda Rivero-Pérez, David Bartolomé‐Martín, Diego Álvarez de la Rosa, Geoffrey W. Abbott +2 more

Case report: A novel loss-of-function pathogenic variant in the KCNA1 cytoplasmic N-terminus causing carbamazepine-responsive type 1 episodic ataxia

Frontiers in Neurology(2022)10.3389/fneur.2022.975849

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8 citations

Richard Sidlow, Geoffrey W. Abbott, Rían W. Manville

KCNQ5 activation by tannins mediates vasorelaxant effects of barks used in Native American botanical medicine

The FASEB Journal(2022)10.1096/fj.202200724r

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11 citations

Kaitlyn E. Redford, Jennifer van der Horst, Derk J. Hogenkamp, Thomas A. Jepps, Geoffrey W. Abbott +1 more

Ancient medicinal plant rosemary contains a highly efficacious and isoform-selective KCNQ potassium channel opener

Communications Biology(2023)10.1038/s42003-023-05021-8

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16 citations

Derk J. Hogenkamp, Geoffrey W. Abbott, Rían W. Manville

Native American ataxia medicines rescue ataxia-linked mutant potassium channel activity via binding to the voltage sensing domain

Nature Communications(2023)10.1038/s41467-023-38834-6

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14 citations

J. Alfredo Freites, Richard Sidlow, Douglas J. Tobias, Geoffrey W. Abbott, Rían W. Manville

Medicinal plant rosemary relaxes blood vessels by activating vascular smooth muscle KCNQ channels

The FASEB Journal(2023)10.1096/fj.202301132r

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13 citations

Samuel N. Baldwin, Emil Ørnberg Eriksen, Thomas A. Jepps, Geoffrey W. Abbott, Rían W. Manville

Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity

Neuron(2024)10.1016/j.neuron.2024.07.018

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12 citations

Katrina Bartas, May Hui, Lingxuan Chen, José Vásquez, Ghalia Azouz +11 more

A novel autism-associated KCNB1 mutation dramatically slows Kv2.1 potassium channel activation, deactivation and inactivation

Frontiers in Cellular Neuroscience(2024)10.3389/fncel.2024.1438101

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7 citations

Samantha D. Block, Claire L. Illeck, Jessica Kottmeier, Richard Sidlow, Geoffrey W. Abbott +1 more

Polymodal K+ channel modulation contributes to dual analgesic and anti-inflammatory actions of traditional botanical medicines

Communications Biology(2024)10.1038/s42003-024-06752-y

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6 citations

Ryan F. Yoshimura, Andriy V. Yeromin, Derk J. Hogenkamp, Jennifer van der Horst, Angel Zavala +10 more

Discovery of a potent, Kv7.3-selective potassium channel opener from a Polynesian traditional botanical anticonvulsant

Communications Chemistry(2024)10.1038/s42004-024-01318-9

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3 citations

Rían W. Manville, Geoffrey W. Abbott

A novel loss-of-function KCNB1 gene variant in a twin with global developmental delay and seizures

Frontiers in Cellular Neuroscience(2024)10.3389/fncel.2024.1477989

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0 citations

Claire L. Illeck, César Miguel Momesso, Richard Sidlow, Geoffrey W. Abbott, Rían W. Manville

The molecular basis of pH sensing by the human fungal pathogen Candida albicans TOK potassium channel

iScience(2024)10.1016/j.isci.2024.111451

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0 citations

Claire L. Illeck, Anthony Lewis, Zoe A. McCrossan, Steven A. Goldstein, Geoffrey W. Abbott +1 more

Comment on “The quercetin metabolite 4-methylcatechol causes vasodilation via voltage-gated potassium (Kv) channels” by Patrícia Dias, Rudy Salam, Jana Pourová, Marie Vopršalová, Lukáš Konečný, Eduard Jirkovský, Jurjen Duintjer Tebbens and Přemysl Mladěnka, Food & Function , 2024, 15 , 11047

Food & Function(2025)10.1039/d4fo06086e

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1 citations

Hạnh Thị Thuý Nguyễn, Geoffrey W. Abbott, Rían W. Manville

Vasorelaxant effects of 3-methoxycatechol are not via direct activation of voltage-gated potassium channels

Vascular Pharmacology(2025)10.1016/j.vph.2025.107471

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0 citations

Samuel N. Baldwin, Olivia H Schaub, Thomas A. Jepps, Geoffrey W. Abbott, Rían W. Manville

Engineering substrate selectivity in the human sodium/iodide symporter (NIS)

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.07.681042

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0 citations

Haswitha Sabbineni, Kendra Hoffsmith, Rían W. Manville, David López-González, Andrea Reyna‐Neyra +5 more

Allosteric regulation of mammalian Na+/I− symporter activity by perchlorate

Nature Structural & Molecular Biology(2020)10.1038/s41594-020-0417-5

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52 citations

Rían W. Manville, Andrea Reyna‐Neyra, Geoffrey W. Abbott, L. Mario Amzel, Nancy Carrasco +1 more

Protocol to study human Kv1.2 potassium channel pathogenic sequence variants using two-electrode voltage-clamp technique

STAR Protocols(2025)10.1016/j.xpro.2025.104217

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0 citations

Geoffrey W. Abbott, Rían W. Manville