Sigan L. Hartley

MedicinePsychologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 47 papers. Top paper: “Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome”.

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

Journal of Alzheimer s Disease(2020)10.3233/jad-201167

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0.598DataRank · unranked

53 citations

Michael S. Rafii, Fan Zhang, James Hall, David Julovich, Beau M. Ances +20 more

PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer's disease progression in Down syndrome

NeuroImage(2021)10.1016/j.neuroimage.2021.117728

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0.581DataRank · unranked

47 citations

Dana Tudorascu, Charles M. Laymon, Sigan L. Hartley, Shahid Zaman, Beau M. Ances +8 more

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00084-x

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0.542DataRank · unranked

36 citations

Nicole S. McKay, Anna H. Boerwinkle, James L. Kennedy, Shaney Flores, Benjamin L. Handen +86 more

Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae331

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0.510DataRank · unranked

29 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +70 more

Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00426-5

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0.505DataRank · unranked

28 citations

Matthew Zammit, Jiebiao Wang, Benjamin L. Handen, Tobey J. Betthauser, Charles M. Laymon +71 more

Brain outcomes with lifestyle change in adults with Down syndrome: Rationale and design for a 12‐month randomized trial

Alzheimer s & Dementia(2025)10.1002/alz.70219

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0.216DataRank · unranked

3 citations

Joseph E. Donnelly, Jeffery Burns, Jill K. Morris, Sigan L. Hartley, Laura E. Martin +11 more

The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer’s disease

Brain(2025)10.1093/brain/awaf428

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0.165DataRank · unranked

2 citations

Hailey Bruzzone, Karly Alex Cody, Jacob Morse, Rachael E. Wilson, Brecca Bettcher +65 more

Language and executive functioning in young adults with Down syndrome

Journal of Intellectual Disability Research(2021)10.1111/jir.12868

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0DataRank · unranked

20 citations

K. M. Lorenz, Xin Zhou, Brianna Piro‐Gambetti, Sigan L. Hartley, Shelly P. Godar +4 more

White matter microstructure associations to amyloid burden in adults with Down syndrome

NeuroImage Clinical(2021)10.1016/j.nicl.2021.102908

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0DataRank · unranked

6 citations

Matthew Zammit, Minjie Wu, Patrick J. Lao, Douglas Dean, Sterling C. Johnson +12 more

Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease.

Apollo (University of Cambridge)(2021)10.17863/cam.71177

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0DataRank · unranked

0 citations

R. Asaad Baksh, Bessy Benejam, Jessica Beresford‐Webb, Antonia Coppus, Juan Fortea +14 more

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2022)10.1016/s1474-4422(22)00408-2

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0DataRank · unranked

56 citations

Brian A. Gordon, Julie K. Wisch, Shaney Flores, Rachel L. Henson, Omar H. Butt +95 more

Obstructive sleep apnea, cerebrovascular disease, and amyloid in older adults with Down syndrome across the Alzheimer’s continuum

SLEEP Advances(2022)10.1093/sleepadvances/zpac013

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0DataRank · unranked

20 citations

Molly E. Zimmerman, Sigan L. Hartley, José Gutierrez, David B. Keator, Kay C. Igwe +16 more

A modified Cued Recall Test for detecting prodromal AD in adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2022)10.1002/dad2.12361

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0DataRank · unranked

27 citations

Sigan L. Hartley, Christy Hom, Margaret B. Pulsifer, I. C. H. Clare, Benjamin L. Handen +4 more

Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome

Disability and health journal(2022)10.1016/j.dhjo.2022.101278

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0DataRank · unranked

20 citations

Victoria Fleming, Brianna Piro‐Gambetti, Annie Cohen, Beau M. Ances, Michael A. Yassa +13 more

Weight Loss and Alzheimer’s Disease in Down Syndrome

Journal of Alzheimer s Disease(2022)10.3233/jad-220865

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0DataRank · unranked

12 citations

Brian C. Helsel, Lauren T. Ptomey, H. Diana Rosas, Benjamin L. Handen, Charles M. Laymon +10 more

Physical activity, memory function, and hippocampal volume in adults with Down syndrome

Frontiers in Integrative Neuroscience(2022)10.3389/fnint.2022.919711

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0DataRank · unranked

9 citations

Benjamin L. Handen, Charles M. Laymon, Victoria Fleming, Brianna Piro‐Gambetti, Bradley Christian +5 more

Cognitive outcome measures for tracking Alzheimer's disease in Down syndrome

International review of research in developmental disabilities(2022)10.1016/bs.irrdd.2022.05.006

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0DataRank · unranked

5 citations

Christy Hom, I. C. H. Clare, Shemaya L. Hurd-Thomas, Sharon J. Krinsky‐McHale, Benjamin L. Handen +2 more

Characterizing the emergence of amyloid and tau burden in Down syndrome

Alzheimer s & Dementia(2023)10.1002/alz.13444

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0DataRank · unranked

65 citations

Tobey J. Betthauser, Andrew K McVea, Charles M. Laymon, Dana Tudorascu, Sterling C. Johnson +12 more

AT(N) biomarker profiles and Alzheimer's disease symptomology in Down syndrome

Alzheimer s & Dementia(2023)10.1002/alz.13446

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0DataRank · unranked

21 citations

Benjamin L. Handen, Dana Tudorascu, Laisze Lee, Annie Cohen, Emily K. Schworer +11 more

Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome

Alzheimer s & Dementia(2023)10.1002/alz.13506

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0DataRank · unranked

13 citations

Muhammad Aslam, Lam‐Ha T. Dang, Laura Xicota, María Victoria Fernández, Yun Ju Sung +16 more

Assessing amyloid PET positivity and cognitive function in Down syndrome to guide clinical trials targeting amyloid

Alzheimer s & Dementia(2024)10.1002/alz.14068

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0DataRank · unranked

17 citations

Caihong Yan, Sigan L. Hartley, Ben L. Handen, Julie K. Wisch, Anna H. Boehrwinkle +3 more

Adapting prescribing criteria for amyloid‐targeted antibodies for adults with Down syndrome

Alzheimer s & Dementia(2024)10.1002/alz.13778

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0DataRank · unranked

18 citations

Richard A. Fisher, Matthew P. Janicki, Brian Chicoine, Bradley T. Christian, Anna J. Esbensen +17 more

Cognitive and functional performance and plasma biomarkers of early Alzheimer's disease in Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2024)10.1002/dad2.12582

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0DataRank · unranked

16 citations

Benjamin L. Handen, Melissa Petersen, Sid E. O’Bryant, Jamie C. Peven, Dana Tudorascu +17 more

Comparative analysis of electrodermal activity metrics and their association with child behavior in autism spectrum disorder

Developmental Psychobiology(2024)10.1002/dev.22461

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0DataRank · unranked

10 citations

Emily Lorang, Robert H. Olson, Geovanna Rodriquez, Dasoo Milton Yoon, Sigan L. Hartley +1 more

The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome

EBioMedicine(2024)10.1016/j.ebiom.2024.105433

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0DataRank · unranked

6 citations

Lam‐Ha T. Dang, Alice Lee, Sharon J. Krinsky‐McHale, Deborah Pang, Lisa Melilli +72 more

An exploratory study of resilience to stressful life events in autistic children

Research in autism spectrum disorders(2024)10.1016/j.rasd.2024.102371

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0DataRank · unranked

0 citations

Jennifer M. Putney, Emily Hickey, Marcia A. Winter, Sigan L. Hartley, Jessica L. Greenlee

The Alzheimer's Biomarker Consortium–Down Syndrome (ABC‐DS): A 10‐year report

Alzheimer s & Dementia(2025)10.1002/alz.70294

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0DataRank · unranked

21 citations

Mark Mapstone, Sigan L. Hartley, Howard Andrews, Brad T. Christian, Joseph H. Lee +20 more

The striatum is an early, accurate indicator of amyloid burden using [ 11 C]PiB in Down syndrome: Comparison of two radiotracers

Alzheimer s & Dementia(2025)10.1002/alz.70141

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0DataRank · unranked

12 citations

Brecca Bettcher, Andrew K McVea, Alexandra H DiFilippo, Matthew Zammit, Lisette LeMerise +21 more

Resistance and resilience to Alzheimer's disease in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70151

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0DataRank · unranked

13 citations

Elouise A. Koops, Beau M. Ances, Elizabeth J. Andrews, Eider M. Arenaza‐Urquijo, Alexandre Bejanin +40 more

Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI

Journal of Neuropathology & Experimental Neurology(2025)10.1093/jnen/nlaf010

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0DataRank · unranked

6 citations

Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh +69 more

PET‐measured amyloid beta accumulates at an accelerated rate in Down syndrome compared to neurotypical populations

Alzheimer s & Dementia(2025)10.1002/alz.70357

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0DataRank · unranked

4 citations

Alexandra H DiFilippo, Max McLachlan, Brecca Betcher, Matthew Zammit, Tobey J. Betthauser +20 more

Lifestyle Composite and Resilience to Alzheimer's Disease Pathology in Down Syndrome

Journal of Applied Research in Intellectual Disabilities(2025)10.1111/jar.70109

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0DataRank · unranked

4 citations

Matthew Zammit, Benjamin L. Handen, Brianna Piro‐Gambetti, Melissa Jenkins, Courtney E Brothers +6 more

Eye Tracking as a Tool for Detecting Alzheimer's Disease in People With Down Syndrome

Journal of Intellectual Disability Research(2025)10.1111/jir.13214

N/A

0DataRank · unranked

6 citations

Sharon J. Krinsky‐McHale, Cynthia Kovacs, Benjamin L. Handen, Bradley T. Christian, Charles M. Laymon +8 more

Longitudinal diffusion tensor imaging correlates with amyloid burden in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70572

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0DataRank · unranked

2 citations

José Guerrero-González, Andrew K McVea, Matthew Zammit, Steven Kecskemeti, Sigan L. Hartley +7 more

A comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials

Brain Communications(2025)10.1093/braincomms/fcaf406

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0DataRank · unranked

2 citations

Julie C. Price, Bradley T. Christian, Michael S. Rafii, Beau M. Ances, Howard Andrews +51 more

Imaging and plasma biomarkers for pathological accumulation in Down syndrome

Brain(2025)10.1093/brain/awaf418

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0DataRank · unranked

2 citations

Ziqiao Jiao, James T. Kennedy, Ann D. Cohen, Zinayida Schlachetzki, Melissa Petersen +21 more

Genetically determined Alzheimer's disease research advances: The Down Syndrome & Autosomal Dominant Alzheimer's Disease 2024 Conference

Alzheimer s & Dementia(2025)10.1002/alz.70309

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0DataRank · unranked

4 citations

Lucía Maure-Blesa, Beau M. Ances, Lisi Flores Aguilar, Sigan L. Hartley, Jason Hassenstab +54 more

Preliminary investigation of obstructive sleep apnea and Alzheimer’s disease in down syndrome

SLEEP Advances(2025)10.1093/sleepadvances/zpaf044

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0DataRank · unranked

1 citations

David T. Plante, Victoria Fleming, Benjamin L. Handen, Patrick J. Lao, Jamie C. Peven +8 more

Parent dyadic coping and parent-child relationship quality in families of autistic children

Research in Autism(2025)10.1016/j.reia.2025.202695

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0DataRank · unranked

0 citations

Jessica L. Greenlee, Dasoo Milton Yoon, Melissa Jenkins, Brianna Piro‐Gambetti, Sigan L. Hartley +1 more

The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12065

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0DataRank · unranked

122 citations

Ira T. Lott, Bradley T. Christian, Nicole Schupf, Sid E. O’Bryant, Mark Mapstone +17 more

Stressful life experiences and mental health symptoms in adults with down syndrome

Research in Developmental Disabilities(2025)10.1016/j.ridd.2025.105152

N/A

0DataRank · unranked

0 citations

Jessica L. Greenlee, Melissa Jenkins, Emily K. Schworer, Courtney E Brothers, Christy Hom +3 more

Association of sleep with cognition and beta amyloid accumulation in adults with Down syndrome

Neurobiology of Aging(2020)10.1016/j.neurobiolaging.2020.04.018

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0DataRank · unranked

36 citations

Brianna Piro‐Gambetti, Matthew Zammit, Bradley T. Christian, Benjamin L. Handen, William E. Klunk +5 more

Alzheimer's disease associated with Down syndrome: a genetic form of dementia

The Lancet Neurology(2021)10.1016/s1474-4422(21)00245-3

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0DataRank · unranked

358 citations

Shahid Zaman, Sigan L. Hartley, Michael S. Rafii, Elizabeth Head, María Carmona‐Iragui +1 more

Physical activity and cognitive and imaging biomarkers of Alzheimer's disease in down syndrome

Neurobiology of Aging(2021)10.1016/j.neurobiolaging.2021.07.016

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0DataRank · unranked

40 citations

Brianna Piro‐Gambetti, Austin L. Patrick, Matthew Zammit, Andrew L. Alexander, Bradley T. Christian +9 more

Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2021)10.1002/dad2.12184

N/A

0DataRank · unranked

30 citations

R. Asaad Baksh, Bessy Benejam, Jessica Beresford‐Webb, Antonia Coppus, Juan Fortea +14 more

Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

NeuroImage Clinical(2021)10.1016/j.nicl.2021.102740

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0DataRank · unranked

28 citations

Dana Tudorascu, Charles M. Laymon, Sigan L. Hartley, Paul A. Ellison, Shahid Zaman +10 more

White matter microstructure associations with episodic memory in adults with Down syndrome: a tract-based spatial statistics study

Journal of Neurodevelopmental Disorders(2021)10.1186/s11689-021-09366-1

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0DataRank · unranked

26 citations

Matthew Zammit, Minjie Wu, Douglas Dean, Sterling C. Johnson, Dana Tudorascu +11 more