Adam Burkholder

Also affiliated with National Institute of Environmental Health Sciences

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.830Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Comprehensive evaluation of smoking exposures and their interactions on DNA methylation

EBioMedicine(2024)10.1016/j.ebiom.2023.104956

Top 24%

0.830DataRank

Top 24%42 citations

Yunsung Lee, Daniel L. McCartney, Elin T.G. Kersten, Christian M. Page, Paige M. Hulls +70 more

Papers

Driven by 38 papers — median percentile 76. Top paper: “Increased Burden of Rare Sequence Variants in GnRH-Associated Genes in Women With Hypothalamic Amenorrhea”.

Increased Burden of Rare Sequence Variants in GnRH-Associated Genes in Women With Hypothalamic Amenorrhea

The Journal of Clinical Endocrinology & Metabolism(2020)10.1210/clinem/dgaa609

N/A

1.0DataRank · unranked

24 citations

Adam Burkholder, Christopher A. Lavender, Lacey Plummer, Verónica Mericq, Paulina M. Merino +12 more

Comprehensive evaluation of smoking exposures and their interactions on DNA methylation

EBioMedicine(2024)10.1016/j.ebiom.2023.104956

Top 24%

0.830DataRank

Top 24%42 citations

Yunsung Lee, Daniel L. McCartney, Elin T.G. Kersten, Christian M. Page, Paige M. Hulls +70 more

Instability throughout the Saccharomyces cerevisiae genome resulting from Pms1 endonuclease deficiency

Nucleic Acids Research(2024)10.1093/nar/gkae616

N/A

0.377DataRank · unranked

7 citations

Marta A. Garbacz, Sascha Emilie Liberti, Adam Burkholder, Thomas A. Kunkel, Scott A. Lujan

High fidelity DNA ligation prevents single base insertions in the yeast genome

Nature Communications(2024)10.1038/s41467-024-53063-1

N/A

0.208DataRank · unranked

3 citations

Scott A. Lujan, Mercedes E. Arana, Adam Burkholder, Percy Tumbale, R. Scott Williams +2 more

A multi-ancestry genome-wide association study identifies novel candidate loci in the RARB gene associated with hypertensive disorders of pregnancy

Human Genetics and Genomics Advances(2024)10.1016/j.xhgg.2024.100385

N/A

0.109DataRank · unranked

1 citations

Adam Burkholder, Farida S. Akhtari, John S. House, Ulla Sovio, Gordon C. S. Smith +5 more

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

UNC Libraries(2020)10.17615/1kpj-1p06

N/A

0DataRank · unranked

0 citations

David C. Fargo, Adam Burkholder, Scott A. Lujan, Piotr A. Mieczkowski, Duncan J. Smith +5 more

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

UNC Libraries(2020)10.17615/1sxk-p977

N/A

0DataRank · unranked

0 citations

Scott A. Lujan, Dmitry A. Gordenin, Allan Clark, Ewa P. Malc, Anders R. Clausen +6 more

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

PLoS Genetics(2021)10.1371/journal.pgen.1009302

N/A

0DataRank · unranked

56 citations

Camille K. Giacobone, Leszek J. Klimczak, Brian N. Papas, Adam Burkholder, Jian‐Liang Li +7 more

How asymmetric DNA replication achieves symmetrical fidelity

Nature Structural & Molecular Biology(2021)10.1038/s41594-021-00691-6

N/A

0DataRank · unranked

26 citations

Scott A. Lujan, Adam Burkholder, Jordan St. Charles, Joseph M. Dahl, Corinne E. Farrell +3 more

The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe–S cluster in DNA polymerase δ

Nucleic Acids Research(2021)10.1093/nar/gkab371

N/A

0DataRank · unranked

12 citations

Margaret Dominska, Tony Zhang, Joseph M. Dahl, Elena I. Stepchenkova, Piotr A. Mieczkowski +6 more

A post-transcriptional regulon controlled by TtpA, the single tristetraprolin family member expressed in Dictyostelium discoideum

Nucleic Acids Research(2021)10.1093/nar/gkab983

N/A

0DataRank · unranked

5 citations

Melissa L. Wells, Wi S. Lai, Stephanie N. Hicks, Adam Burkholder, L. Perera +3 more

The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming

UNC Libraries(2021)10.17615/crwe-7153

N/A

0DataRank · unranked

4 citations

Carmen J. Williams, Yongsheng Shi, Guang Hu, Konrad Hochedlinger, David C. Fargo +10 more

Mitochondrial-nuclear epistasis underlying phenotypic variation in breast cancer pathology

Scientific Reports(2022)10.1038/s41598-022-05148-4

N/A

0DataRank · unranked

13 citations

James M. Ward, Adam Burkholder, Jianying Li, Benedict Anchang, Pierre R. Bushel

Opioid Medication Use and Blood Dna Methylation: Epigenome-Wide Association Meta-Analysis

Epigenomics(2022)10.2217/epi-2022-0353

N/A

0DataRank · unranked

11 citations

Roby Joehanes, Daniel L. McCartney, Minjung Kho, Anke Hüls, Annah B. Wyss +17 more

Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort

Diabetes Care(2022)10.2337/dc22-0295

N/A

0DataRank · unranked

10 citations

Dillon Lloyd, Adam Burkholder, Xiaoran Tong, John S. House, Eunice Lee +7 more

Pif1 family helicases promote mutation avoidance during DNA replication

Nucleic Acids Research(2022)10.1093/nar/gkac1127

N/A

0DataRank · unranked

4 citations

Cindy Follonier, Scott A. Lujan, Adam Burkholder, Virginia A. Zakian, Thomas A. Kunkel +1 more

Detection of DNA replication errors and 8-oxo-dGTP-mediated mutations in E. coli by Duplex DNA Sequencing

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.21.513255

N/A

0DataRank · unranked

0 citations

Adam Burkholder, Roel M. Schaaper, Niketa Bhawsinghka

Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans

Nucleic Acids Research(2023)10.1093/nar/gkad611

N/A

0DataRank · unranked

14 citations

Leszek J. Klimczak, Joan F. Sterling, Adam Burkholder, Marat D. Kazanov, Natalie Saini +3 more

DUX4 double whammy: The transcription factor that causes a rare muscular dystrophy also kills the precursors of the human nose

Science Advances(2023)10.1126/sciadv.abq7744

N/A

0DataRank · unranked

12 citations

Hamed Bostan, MaKenna R. Browne, Owen F. Bevis, Carl D. Bortner, Steven A. Moore +7 more

Detection of DNA replication errors and 8-oxo-dGTP-mediated mutations in E. coli by Duplex DNA Sequencing

DNA repair(2023)10.1016/j.dnarep.2023.103462

N/A

0DataRank · unranked

9 citations

Adam Burkholder, Roel M. Schaaper, Niketa Bhawsinghka

Synergistic roles of tristetraprolin family members in myeloid cells in the control of inflammation

Life Science Alliance(2023)10.26508/lsa.202302222

N/A

0DataRank · unranked

9 citations

Rui Huang, Adam Burkholder, Danielle Donahue, Beth Mahler, Carl D. Bortner +3 more

Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma

Frontiers in Genetics(2023)10.3389/fgene.2023.1173676

N/A

0DataRank · unranked

8 citations

Wonson Choi, Adam Burkholder, L. Perera, Jasmine A. Mack, Frederick W. Miller +13 more

Vanadium Pentoxide Exposure Causes Strain-Dependent Changes in Mitochondrial DNA Heteroplasmy, Copy Number, and Lesions, but Not Nuclear DNA Lesions

International Journal of Molecular Sciences(2023)10.3390/ijms241914507

N/A

0DataRank · unranked

1 citations

Steven R. Kleeberger, Adam Burkholder, Dianne M. Walters, Wesley Gladwell, Kevin Gerrish +2 more

A multi-ancestry genome-wide association study identifies novel candidate loci in the RARB gene associated with hypertensive disorders of pregnancy

medRxiv(2023)10.1101/2023.10.30.23297806

N/A

0DataRank · unranked

1 citations

Adam Burkholder, Farida S. Akhtari, John S. House, Ulla Sovio, Gordon C. S. Smith +5 more

Hypomorphic mutation in the large subunit of replication protein A affects mutagenesis by human APOBEC cytidine deaminases in yeast

G3 Genes Genomes Genetics(2024)10.1093/g3journal/jkae196

N/A

0DataRank · unranked

6 citations

Zachary W. Kockler, Steven A. Roberts, Adam Burkholder, Leszek J. Klimczak, Dmitry A. Gordenin +1 more

Evidence that DNA polymerase δ proofreads errors made by DNA polymerase α across the Saccharomyces cerevisiae nuclear genome

DNA repair(2024)10.1016/j.dnarep.2024.103768

N/A

0DataRank · unranked

3 citations

Zhi-Xiong Zhou, Scott A. Lujan, Adam Burkholder, Thomas A. Kunkel, Sarah A Marks

Joint modeling of genomic and exposomic data reveals a substantial GxE component in type 2 diabetes etiology

Research Square(2024)10.21203/rs.3.rs-3832061/v1

N/A

0DataRank · unranked

0 citations

Xiaoran Tong, John S. House, Adam Burkholder, David C. Fargo, Charles Schmitt +3 more

Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort

UNC Libraries(2024)10.17615/xqbp-5w10

N/A

0DataRank · unranked

0 citations

Schurman S.H, Schmitt C.P, John B. Buse, Lee E.Y, Fargo D.C +7 more

Hypomorphic mutation in the large subunit of replication protein A affects mutagenesis by human APOBEC cytidine deaminases in yeast

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.27.601081

N/A

0DataRank · unranked

0 citations

Zachary W. Kockler, Steven A. Roberts, Adam Burkholder, Leszek J. Klimczak, Dmitry A. Gordenin +1 more

Prenatal Smoking Exposures and Epigenome-Wide Methylation in Newborn Blood

Environmental Health Perspectives(2025)10.1021/ehp.6c00142

N/A

0DataRank · unranked

3 citations

Marta Cosín‐Tomás, Yunsung Lee, Giulietta S. Monasso, Zongli Xu, Shaobo Li +51 more

Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score

medRxiv(2025)10.1101/2025.06.20.25329522

N/A

0DataRank · unranked

1 citations

Andrew S. Bell, Dominika A. Michalek, Adam Burkholder, Stella Nam, Raymond J. Kreienkamp +14 more

Implementing secondary findings analysis in a genetic and environmental research study

Genetics in Medicine(2025)10.1016/j.gim.2025.101515

N/A

0DataRank · unranked

0 citations

Julie C. Sapp, Seeley Yoo, Zara Wermers, Sophia Hernandez, Alison A. Motsinger‐Reif +6 more

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging

Genome biology(2020)10.1186/s13059-020-02138-5

N/A

0DataRank · unranked

103 citations

Matthew J. Longley, Margaret H. Humble, Christopher A. Lavender, Adam Burkholder, Emma L. Blakely +8 more

Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans

UNC Libraries(2025)10.17615/gzbt-8003

N/A

0DataRank · unranked

0 citations

Piotr A. Mieczkowski, Marat D. Kazanov, Natalie Saini, Leszek J. Klimczak, Joan F. Sterling +3 more

Association between Mitochondrial DNA Sequence Variants and V˙O2 max Trainability

Medicine & Science in Sports & Exercise(2020)10.1249/mss.0000000000002390

N/A

0DataRank · unranked

20 citations

Kirsten C. Verhein, Adam Burkholder, Jaehoon Lee, Young-Min Kim, J. Timothy Lightfoot +6 more

Investigation of the adolescent female breast transcriptome and the impact of obesity

Breast Cancer Research(2020)10.1186/s13058-020-01279-6

N/A

0DataRank · unranked

14 citations

Dennis Akrobetu, Arun R. Pandiri, Kiki Ton, Sue Kim, Brian I. Labow +6 more

H/ACA snoRNA levels are regulated during stem cell differentiation

Nucleic Acids Research(2020)10.1093/nar/gkaa612

N/A

0DataRank · unranked

45 citations

Sanam L. Kavari, Adam Burkholder, Bart Phillips, Traci M. Tanaka Hall, Kathleen L. McCann

Biochromoendoscopy: molecular imaging with capsule endoscopy for detection of adenomas of the GI tract

UNC Libraries(2020)10.17615/59hk-z553

N/A

0DataRank · unranked

0 citations

Nicole M. Ramocki, Douglas R. Morgan, Howard Zhang, P. Kay Lund, Gerald Cecil +2 more

Adam Burkholder

Indexed papers

Top data-sharing exemplar

Papers