Hening Lin

Also affiliated with Cornell University, University of Illinois Chicago, University of Chicago, University of Chicago Medical Center, Forma Therapeutics (United States)

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 47 papers. Top paper: “Reversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling”.

Reversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2119678119

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0.917DataRank · unranked

38 citations

Emma Robinson, Tianjing Hu, Ji Cao, Jun Young Hong, Charles A. Tharp +9 more

NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle

Nature Communications(2020)10.1038/s41467-020-14893-x

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0DataRank · unranked

108 citations

Ian R. Price, Xiaoyu Zhang, Cheng‐Liang Zhu, Kayla N. Johnson, Shuai Zhang +9 more

Simultaneous Inhibition of SIRT2 Deacetylase and Defatty-Acylase Activities via a PROTAC Strategy

ACS Medicinal Chemistry Letters(2020)10.1021/acsmedchemlett.0c00423

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0DataRank · unranked

55 citations

Hui Jing, Ian R. Price, Ji Cao, Jessica Jingyi Bai, Hening Lin +1 more

An improved 4′-aminomethyltrioxsalen-based nucleic acid crosslinker for biotinylation of double-stranded DNA or RNA

RSC Advances(2020)10.1039/d0ra07437c

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0DataRank · unranked

10 citations

Miao Wang, Min Yang, Abdullah Ozer, John T. Lis, Hening Lin +1 more

An Improved 4’-Aminomethyltroxsalen-Based DNA Crosslinker for Biotinylation of DNA

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.29.971317

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0DataRank · unranked

0 citations

Miao Wang, Min Yang, Abdullah Ozer, John T. Lis, Hening Lin +1 more

Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation

Annual Review of Biochemistry(2021)10.1146/annurev-biochem-082520-125411

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0DataRank · unranked

166 citations

Hening Lin, Miao Wang

Protein cysteine palmitoylation in immunity and inflammation

FEBS Journal(2021)10.1111/febs.15728

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0DataRank · unranked

86 citations

Hening Lin

Sirtuin Modulators in Cellular and Animal Models of Human Diseases

Frontiers in Pharmacology(2021)10.3389/fphar.2021.735044

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0DataRank · unranked

39 citations

Hening Lin, Jun Young Hong

Lysine Fatty Acylation: Regulatory Enzymes, Research Tools, and Biological Function

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.717503

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0DataRank · unranked

34 citations

Hening Lin, Garrison Komaniecki

Diphthamide promotes TOR signaling by increasing the translation of proteins in the TORC1 pathway

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2104577118

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0DataRank · unranked

8 citations

Zhewang Lin, Julia Zhu, Miao Wang, Hening Lin, Yugang Zhang

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s disease

Nature Communications(2022)10.1038/s41467-021-27572-2

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0DataRank · unranked

114 citations

Vı́ctor Tapias, Diana Acosta, Hui Xu, Huan‐Lian Chen, Ruchika Bhawal +14 more

Substrate-selective small-molecule modulators of enzymes: Mechanisms and opportunities

Current Opinion in Chemical Biology(2022)10.1016/j.cbpa.2022.102231

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0DataRank · unranked

21 citations

Hening Lin

Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2117013119

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0DataRank · unranked

32 citations

Ornella D. Nelson, Ian R. Price, Cheng‐Liang Zhu, Xuan Lü, Irma Fernández +3 more

Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation

Nature Communications(2022)10.1038/s41467-022-32227-x

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0DataRank · unranked

24 citations

Yugang Zhang, Garrison Komaniecki, Xuan Lü, Ji Cao, Mingming Zhang +7 more

The Acyl-CoA Specificity of Human Lysine Acetyltransferase KAT2A

Biochemistry(2022)10.1021/acs.biochem.2c00308

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0DataRank · unranked

18 citations

Yuxiang Ren, Qin Fu, Zhisheng Zhang, Hening Lin, Ananya Anmangandla

Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity

Biochemistry(2022)10.1021/acs.biochem.2c00583

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0DataRank · unranked

16 citations

Maria Del Carmen Camarena, Eric Gelsleichter, Rachel G. Mendoza, Mark A. Subler, Jolene J. Windle +5 more

A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions

Molecular & Cellular Proteomics(2022)10.1016/j.mcpro.2022.100268

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0DataRank · unranked

10 citations

George Maio, Xiaoyu Zhang, Felix S. Badillo Soto, Julia Zhu, Stephen Z. Ramirez +2 more

Oxygen level regulates N-terminal translation elongation of selected proteins through deoxyhypusine hydroxylation

Cell Reports(2022)10.1016/j.celrep.2022.110855

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0DataRank · unranked

9 citations

Dan Su, Julia Zhu, Miao Wang, Yandong Zhang, Qin Fu +3 more

IGF2BP2 Promotes Cancer Progression by Degrading the RNA Transcript Encoding a v‐ATPase Subunit

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7433

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0DataRank · unranked

0 citations

Arash Latifkar, James Mullmann, Elena Panizza, Irma Fernández, Lu Ling +7 more

Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11

ACS Chemical Biology(2023)10.1021/acschembio.2c00840

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28 citations

Changmin Peng, Edward Seto, Hening Lin, Thanh Tu Ho

Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity

Haematologica(2023)10.3324/haematol.2022.281894

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0DataRank · unranked

24 citations

Tianyi Ling, Jacob M. Berman, Rachel Culp‐Hill, Julie A. Reisz, Vincent Rondeau +22 more

A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain

ACS Chemical Biology(2023)10.1021/acschembio.3c00092

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0DataRank · unranked

14 citations

Sadhan Jana, Kewen Peng, Shamar D. Wallace, Saket R. Bagde, Bryon Drown +5 more

Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100709

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0DataRank · unranked

4 citations

M.A. Smith, Ruchika Bhawal, Sheng Zhang, Jeremy M. Baskin, Jenny Li +2 more

NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.07.566005

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0DataRank · unranked

8 citations

Dan Hou, Jiaqi Zhao, Xuan Lü, Wendy K. Greentree, Qian Zhao +5 more

ATP-release pannexin channels are gated by lysophospholipids

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.23.563601

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0DataRank · unranked

2 citations

Russell N. Burkhardt, Bennett W. Fox, Tyler J. Schwertfeger, Eric Gelsleichter, Kevin Michalski +7 more

Identification of potential HDAC11 deacylase substrates by affinity pulldown MS

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.03.012

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0DataRank · unranked

0 citations

Qian Zhao, Hening Lin, Yandong Zhang

Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis

Cell Metabolism(2024)10.1016/j.cmet.2024.11.005

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0DataRank · unranked

177 citations

Xuelian Ren, Yae Eun Park, Huixu Feng, Xinlei Sheng, Xiaohan Song +13 more

NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation

Cell Reports(2024)10.1016/j.celrep.2024.114070

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0DataRank · unranked

91 citations

Dan Hou, Jiaqi Zhao, Xuan Lü, Wendy K. Greentree, Qian Zhao +5 more

MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2403392121

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0DataRank · unranked

29 citations

Dan Hou, Wenzhe Chen, Xuan Lü, Garrison Komaniecki, Yilai Xu +5 more

Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2319833121

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0DataRank · unranked

22 citations

Tao Yu, Xuan Lü, Jun Young Hong, Min Yang, Yanlin Zi +3 more

Loss of Diphthamide Increases DNA Replication Stress in Mammalian Cells by Modulating the Translation of RRM1

ACS Central Science(2024)10.1021/acscentsci.4c00967

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0DataRank · unranked

16 citations

Byunghyun Ahn, Hening Lin, Jiaqi Zhao

Amino acid and protein specificity of protein fatty acylation in Caenorhabditis elegans

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2307515121

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0DataRank · unranked

8 citations

Yan Yu, Bennett W. Fox, Yinong Liu, Venkatesh P. Thirumalaikumar, Aleksandra Skirycz +3 more

GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains

ACS Chemical Biology(2024)10.1021/acschembio.4c00027

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0DataRank · unranked

2 citations

Shamar D. Wallace, Saket R. Bagde, Jialin Shang, Ananya Anmangandla, Sadhan Jana +3 more

Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors

ACS Chemical Biology(2024)10.1021/acschembio.3c00512

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0DataRank · unranked

2 citations

Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin, Kewen Peng

SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress

eLife(2024)10.7554/elife.97019

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0DataRank · unranked

1 citations

Wendi Teng, Cameron Behram, Hening Lin, Rezwana Karim

Antibiotic target discovery by integrated phenotypic and activity-based profiling of electrophilic fragments

Cell chemical biology(2025)10.1016/j.chembiol.2025.02.001

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0DataRank · unranked

6 citations

Sadhan Jana, Mikail E. Abbasov, Hening Lin, Yizhen Jin

SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress

eLife(2025)10.7554/elife.97019.3

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0DataRank · unranked

5 citations

Wendi Teng, Cameron Behram, Hening Lin, Rezwana Karim

Myristoylation of TMEM106B by NMT1/2 regulates TMEM106B trafficking and turnover

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110322

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0DataRank · unranked

3 citations

Dan Hou, Isis G. Perez, Belvin Gong, Natalia Franco-Hernandez, Angie Yee +5 more

ATP-release pannexin channels are gated by lysophospholipids

eLife(2025)10.7554/elife.107067.2

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0DataRank · unranked

2 citations

Russell N. Burkhardt, Bennett W. Fox, Tyler J. Schwertfeger, Eric Gelsleichter, Kevin Michalski +7 more

SIRT2 Regulates the SMARCB1 Loss-Driven Differentiation Block in ATRT

Molecular Cancer Research(2025)10.1158/1541-7786.mcr-24-0926

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0DataRank · unranked

1 citations

Dong Wang, John DeSisto, Etienne Danis, Senthilnath Lakshmanachetty, Eric Prince +11 more

ATP-release pannexin channels are gated by lysophospholipids

eLife(2025)10.7554/elife.107067

N/A

0DataRank · unranked

2 citations

Russell N. Burkhardt, Bennett W. Fox, Tyler J. Schwertfeger, Eric Gelsleichter, Kevin Michalski +7 more

Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty-acyltransferase

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.18.649563

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0DataRank · unranked

0 citations

Garrison Komaniecki, Jiaze Liu, Hening Lin, Yuxin Mao, Wenjie Zeng

Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty acyltransferase

eLife(2025)10.7554/elife.106975

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0DataRank · unranked

0 citations

Garrison Komaniecki, Jiaze Liu, Hening Lin, Yuxin Mao, Wenjie W Zeng

Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty-acyltransferase

eLife(2025)10.7554/elife.106975.2

N/A

0DataRank · unranked

0 citations

Garrison Komaniecki, Jiaze Liu, Hening Lin, Yuxin Mao, Wenjie Zeng

HDAC5 regulates the activation of cytotoxic CD8+ T cells 4190

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1903

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0DataRank · unranked

0 citations

Cezary Ciszewski, Yandong Zhang, Hening Lin, Bana Jabrì, Megan Borregard

TiPARP forms nuclear condensates to degrade HIF-1α and suppress tumorigenesis

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1921815117

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0DataRank · unranked

115 citations

Ji Cao, Longying Dong, Hening Lin, Lu Zhang

Reviewer #2 (Public review): Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty-acyltransferase

(2025)10.7554/elife.106975.2.sa1

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0DataRank · unranked

0 citations

Garrison Komaniecki, Jiaze Liu, Hening Lin, Yuxin Mao, Wenjie W Zeng