Nicholas H. Oberlies

University of North Carolina at Greensboro

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.799Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus

Microbiology Spectrum(2024)10.1128/spectrum.03980-23

Top 25%

0.799DataRank

Top 25%35 citations

Charu Balamurugan, Huzefa A. Raja, Carla Gonçalves, N. Li, Frank N. Martin +9 more

Papers

Driven by 60 papers — median percentile 75. Top paper: “Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus”.

Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus

Microbiology Spectrum(2024)10.1128/spectrum.03980-23

Top 25%

0.799DataRank

Top 25%35 citations

Charu Balamurugan, Huzefa A. Raja, Carla Gonçalves, N. Li, Frank N. Martin +9 more

Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions

Scientific Reports(2020)10.1038/s41598-020-76119-w

N/A

0.731DataRank · unranked

130 citations

Joshua J. Kellogg, E. Diane Wallace, Manead Khin, Laura Flores‐Bocanegra, Rakshit S. Tanna +8 more

Regulation of gliotoxin biosynthesis and protection in Aspergillus species

PLoS Genetics(2022)10.1371/journal.pgen.1009965

N/A

0.546DataRank · unranked

37 citations

Ana Cristina Colabardini, Maísa Moraes, Maria Augusta Crivelente Horta, Sonja L. Knowles, Huzefa A. Raja +12 more

Evolutionary origin and population diversity of a cryptic hybrid pathogen

Nature Communications(2024)10.1038/s41467-024-52639-1

N/A

0.353DataRank · unranked

8 citations

S E Knowles, Rafael Wesley Bastos, Charu Balamurugan, David C. Rinker, Matthew E. Mead +24 more

Menominin A and B: Cytotoxic Cyclodepsipeptides from the Freshwater Sponge-Associated Cyanobacterium Nostoc sp. UIC 10607

Journal of Natural Products(2025)10.1021/acs.jnatprod.4c01445

N/A

0.342DataRank · unranked

5 citations

Aleksej Krunić, Kelsey L. Alexander, Manead Khin, Jared S. Wood, Cody E. Earp +7 more

Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model

Molecular Pharmaceutics(2024)10.1021/acs.molpharmaceut.3c01088

N/A

0.312DataRank · unranked

7 citations

Katherine D. Lynch, Victoria O. Oyanna, M. Call, Tyler N. Graf, Nicholas H. Oberlies +2 more

Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of Aspergillus fumigatus

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.06.371971

N/A

0.300DataRank · unranked

4 citations

Matthew E. Mead, Patrícia Alves de Castro, Clara Valero, André Damásio, Renato Santos +12 more

Biosynthetic gene clusters, secondary metabolite profiles, and cards of virulence in the closest nonpathogenic relatives of Aspergillus fumigatus

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.09.033902

N/A

0DataRank · unranked

1 citations

Matthew E. Mead, Sonja L. Knowles, Huzefa A. Raja, Christopher D. Roberts, Oliver Bader +5 more

Influence of Dietary Substances on Intestinal Drug Metabolism and Transport

NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro)(2020)10.17615/pqrb-c894

N/A

0DataRank · unranked

0 citations

Mary F. Paine, Nicholas H. Oberlies, Christina S. Won

A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice-Fexofenadine Interaction: An In Vitro-In Vivo “Connect”: The Journal of Clinical Pharmacology

UNC Libraries(2020)10.17615/8ym0-mf79

N/A

0DataRank · unranked

0 citations

Paul A. Dawson, Tian Lan, Mary F. Paine, Wilbur Widmer, Yolanda V. Scarlett +3 more

Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice using Ultra Performance Liquid Chromatography

UNC Libraries(2020)10.17615/c549-5395

N/A

0DataRank · unranked

0 citations

Karen M. VanderMolen, Mary F. Paine, Nicholas H. Oberlies, Nadja B. Cech

Mechanisms underlying food–drug interactions: Inhibition of intestinal metabolism and transport

NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro)(2020)10.17615/8423-ec62

N/A

0DataRank · unranked

0 citations

Christina S. Won, Nicholas H. Oberlies, Mary F. Paine

Labeled content of two furanocoumarins in dietary supplements correlates with neither actual content nor CYP3A inhibitory activity

UNC Libraries(2020)10.17615/vs10-v861

N/A

0DataRank · unranked

0 citations

Karen M. VanderMolen, Nicholas H. Oberlies, Garrett R. Ainslie, Mary F. Paine

Delivery of eupenifeldin via polymer-coated surgical buttresses prevents local lung cancer recurrence

Journal of Controlled Release(2021)10.1016/j.jconrel.2021.01.026

N/A

0DataRank · unranked

16 citations

Ngoc-Quynh Chu, Jeremy T. Korunes‐Miller, Lillian L. Tsai, Tyler N. Graf, Yin P. Hung +6 more

Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin‐drug interactions

Phytotherapy Research(2021)10.1002/ptr.7049

N/A

0DataRank · unranked

11 citations

Michelle L. Montonye, Dandan Tian, Tarana Arman, Victoria O. Oyanna, Baron Bechtold +5 more

Media and strain studies for the scaled production of cis-enone resorcylic acid lactones as feedstocks for semisynthesis

The Journal of Antibiotics(2021)10.1038/s41429-021-00432-3

N/A

0DataRank · unranked

10 citations

Huzefa A. Raja, Jennifer C. Obike, Cedric J. Pearce, Mitchell P. Croatt, Nicholas H. Oberlies +1 more

Regulation of gliotoxin biosynthesis and protection in Aspergillus species

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.16.456458

N/A

0DataRank · unranked

1 citations

Ana Cristina Colabardini, Maísa Moraes, Maria Augusta Crivelente Horta, Sonja L. Knowles, Huzefa A. Raja +12 more

Fungal–fungal co-culture: a primer for generating chemical diversity

Natural Product Reports(2022)10.1039/d1np00070e

N/A

0DataRank · unranked

112 citations

Huzefa A. Raja, Christopher D. Roberts, Nicholas H. Oberlies, Sonja L. Knowles

Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products

Planta Medica(2022)10.1055/a-1795-5876

N/A

0DataRank · unranked

31 citations

Laura Flores‐Bocanegra, Manead Khin, Huzefa A. Raja, Nadja B. Cech, Nicholas H. Oberlies +2 more

H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth

Oncogene(2022)10.1038/s41388-022-02283-0

N/A

0DataRank · unranked

27 citations

Dafeng Yang, John D. Klement, Yolonda L. Colson, Nicholas H. Oberlies, Cedric J. Pearce +7 more

Homoisoflavonoids from the bulbs of Bellevalia longipes and an assessment of their potential cytotoxic activity

Phytochemistry(2022)10.1016/j.phytochem.2022.113343

N/A

0DataRank · unranked

6 citations

Reema Al‐Qiam, Joanna E. Burdette, Ahmed H. Al Sharie, Mohammad Al‐Gharaibeh, Nicholas H. Oberlies +1 more

Polychlorinated cyclopentenes from a marine derived Periconia sp. (strain G1144)

Phytochemistry(2022)10.1016/j.phytochem.2022.113200

N/A

0DataRank · unranked

4 citations

Robert A. Shepherd, Sonja L. Knowles, Manuel Rangel‐Grimaldo, Huzefa A. Raja, Zoie L. Bunch +7 more

Phylogenomics reveals extensive misidentification of fungal strains from the genus Aspergillus

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.22.517304

N/A

0DataRank · unranked

4 citations

Charu Balamurugan, Huzefa A. Raja, Carla Gonçalves, N. Li, Frank N. Martin +8 more

Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma -derived metabolite cues

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.12.516288

N/A

0DataRank · unranked

1 citations

Sara P. Puckett, Andrés Mauricio Caraballo‐Rodríguez, José Rivera‐Chávez, Robert M. Samples, Cody E. Earp +10 more

Pharmacological characterization of kratom alkaloids at opiate receptors: binding affinities, in vitro and in vivo functional assessments

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2549

N/A

0DataRank · unranked

0 citations

Scot McIntosh, Tyler N. Graf, Manuel Rangel‐Grimaldo, Laura Flores‐Bocanegra, Robert A. Coover +2 more

Genomic and phenotypic trait variation of the opportunistic human pathogen Aspergillus flavus and its non-pathogenic close relatives

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.12.499845

N/A

0DataRank · unranked

0 citations

Manuel Rangel‐Grimaldo, Huzefa A. Raja, Hadi Pourhadi, Sonja L. Knowles, Kevin K. Fuller +7 more

Correlative metabologenomics of 110 fungi reveals metabolite–gene cluster pairs

Nature Chemical Biology(2023)10.1038/s41589-023-01276-8

N/A

0DataRank · unranked

54 citations

Fatma Ayaloglu Butun, Matthew T. Robey, Navid J. Ayon, Raveena Gupta, David Dainko +12 more

From plant to cancer drug: lessons learned from the discovery of taxol

Natural Product Reports(2023)10.1039/d3np00017f

N/A

0DataRank · unranked

48 citations

Nicholas H. Oberlies, Nadja B. Cech

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom

Clinical Pharmacology & Therapeutics(2023)10.1002/cpt.2891

N/A

0DataRank · unranked

29 citations

James Nguyen, Deena L. Hadi, Matthew E. Layton, John R. White, Nadja B. Cech +5 more

Translating Kratom-Drug Interactions: From Bedside to Bench and Back

Drug Metabolism and Disposition(2023)10.1124/dmd.122.001005

N/A

0DataRank · unranked

24 citations

Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine +1 more

Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma -derived metabolite cues

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219373120

N/A

0DataRank · unranked

19 citations

Sara P. Puckett, Andrés Mauricio Caraballo‐Rodríguez, José Rivera‐Chávez, Robert M. Samples, Cody E. Earp +10 more

Embellicines C-E: Macrocyclic Alkaloids with a Cyclopenta[b]fluorene Ring System from the Fungus Sarocladium sp.

Journal of Natural Products(2023)10.1021/acs.jnatprod.2c01048

N/A

0DataRank · unranked

10 citations

Laura Flores‐Bocanegra, Huzefa A. Raja, Joanna E. Burdette, Cedric J. Pearce, Nicholas H. Oberlies +1 more

Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice

Drug Metabolism and Disposition(2023)10.1124/dmd.123.001360

N/A

0DataRank · unranked

5 citations

Kenisha Yvette Garcia-Torres, Baron Bechtold, Katherine D. Lynch, M. Call, Miklós Horváth +7 more

Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models

Journal of Natural Products(2023)10.1021/acs.jnatprod.3c00186

N/A

0DataRank · unranked

4 citations

Monica A. Haughan, Manead Khin, Julia Ekiert, Ziwei Zhang, Daniel D. Lantvit +11 more

What was old is new again: Phenotypic screening of a unique fungal library yields pyridoxatin, a promising lead against extensively resistant Acinetobacter baumannii (AB5075)

Phytochemistry Letters(2023)10.1016/j.phytol.2023.04.002

N/A

0DataRank · unranked

3 citations

Laura Flores‐Bocanegra, Kristóf B. Cank, William J. Crandall, Fridah C. Rotich, Madeline N. Tillman +7 more

Sheptide A: an antimalarial cyclic pentapeptide from a fungal strain in the Herpotrichiellaceae

The Journal of Antibiotics(2023)10.1038/s41429-023-00655-6

N/A

0DataRank · unranked

3 citations

Cody E. Earp, Kristóf B. Cank, Huzefa A. Raja, Joanna E. Burdette, Steven P. Maher +8 more

Evolutionary origin, population diversity, and diagnostics for a cryptic hybrid pathogen

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.03.547508

N/A

0DataRank · unranked

11 citations

S E Knowles, Rafael Wesley Bastos, Charu Balamurugan, David C. Rinker, Matthew E. Mead +16 more

Semisynthesis, characterization, and biological evaluation of fluorinated analogues of the spirobisnaphthalene, diepoxin-η

Tetrahedron Letters(2023)10.1016/j.tetlet.2023.154857

N/A

0DataRank · unranked

0 citations

Tamam El‐Elimat, Manuel Rangel‐Grimaldo, Tyler N. Graf, Joseph O. Falkinham, Manead Khin +7 more

Strain heterogeneity in a non-pathogenic Aspergillus fungus highlights factors associated with virulence

Communications Biology(2024)10.1038/s42003-024-06756-8

N/A

0DataRank · unranked

10 citations

Thomas J. C. Sauters, Karin Steffen, Adiyantara Gumilang, Huzefa A. Raja, Manuel Rangel‐Grimaldo +9 more

Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster

Metabolomics(2024)10.1007/s11306-024-02153-8

N/A

0DataRank · unranked

10 citations

Cody E. Earp, Raveena Gupta, Fatma Ayaloglu Butun, Ashley E. Clements, Alexa G. Lee +15 more

Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice

Pharmaceutical Research(2024)10.1007/s11095-024-03662-w

N/A

0DataRank · unranked

7 citations

Baron Bechtold, Katherine D. Lynch, M. Call, Tyler N. Graf, Nicholas H. Oberlies +2 more

Verticillins: fungal epipolythiodioxopiperazine alkaloids with chemotherapeutic potential

Natural Product Reports(2024)10.1039/d3np00068k

N/A

0DataRank · unranked

6 citations

Chiraz Soumia M. Amrine, Michael G. Doyle, Amrita Salvi, Huzefa A. Raja, Jonathan R. Chekan +7 more

Wheldone Revisited: Structure Revision Via DFT-GIAO Chemical Shift Calculations, 1,1-HD-ADEQUATE NMR Spectroscopy, and X-ray Crystallography Studies

Journal of Natural Products(2024)10.1021/acs.jnatprod.4c00649

N/A

0DataRank · unranked

6 citations

Cody E. Earp, Huzefa A. Raja, Jared S. Wood, Lina Mardiana, Kin Lok Ho +7 more

Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice

Drug Metabolism and Disposition(2024)10.1124/dmd.123.001607

N/A

0DataRank · unranked

3 citations

Katherine D. Lynch, Victoria O. Oyanna, M. Call, Laura A. White, Tyler N. Graf +3 more

Strain heterogeneity in a non-pathogenic fungus highlights factors contributing to virulence

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.08.583994

N/A

0DataRank · unranked

1 citations

Thomas J. C. Sauters, Karin Steffen, Adiyantara Gumilang, Huzefa A. Raja, Manuel Rangel‐Grimaldo +9 more

Machine-Readable Structural Information Is Essential for Natural Products Research

Journal of Natural Products(2025)10.1021/acs.jnatprod.5c00836

N/A

0DataRank · unranked

2 citations

Nicholas H. Oberlies, Antonis Rokas, Karin Steffen

A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103597

N/A

0DataRank · unranked

2 citations

Eimear T O'Mahony, Preston K. Manwill, Tyler N. Graf, Nicholas H. Oberlies, Nadja B. Cech +6 more

The importance of verifying biological activity predictions in metabolomics studies of natural products: A case study on antimicrobial properties of Cannabis sativa (hemp)

Phytochemistry Letters(2025)10.1016/j.phytol.2025.103014

N/A

0DataRank · unranked

1 citations

Joseph B. Mangun, Joëlle Houriet, Warren S. Vidar, Tyler N. Graf, Nicholas H. Oberlies +2 more

Studying the molecular mechanisms of tef (Eragrostis tef) antioxidant properties in human THP-1 monocytes

Journal of Functional Foods(2025)10.1016/j.jff.2025.107092

N/A

0DataRank · unranked

1 citations

Tyler N. Graf, Warren S. Vidar, Dereje D. Jima, Nicholas H. Oberlies, Zhenquan Jia +2 more

Verticillin A-Loaded Surgical Buttresses Prevent Local Pancreatic Cancer Recurrence in a Murine Model

Molecular Pharmaceutics(2025)10.1021/acs.molpharmaceut.4c00589

N/A

0DataRank · unranked

2 citations

Herma C. Pierre, Cedric J. Pearce, Mark W. Grinstaff, Aaron H. Colby, Kebin Liu +2 more

Studies on the epipolythiodioxopiperazine alkaloid verticillin D: Scaled production, streamlined purification, and absolute configuration

Phytochemistry(2025)10.1016/j.phytochem.2025.114492

N/A

0DataRank · unranked

2 citations

Dalpat I. Patel, Huzefa A. Raja, Blaise A. Darveaux, Krupa I. Patel, Lina Mardiana +6 more

Redox Homeostasis as a Key Regulator of Intramolecular Cyclization in Fungal Perylenequinones

ACS Chemical Biology(2025)10.1021/acschembio.5c00369

N/A

0DataRank · unranked

1 citations

Firoz Shah Tuglak Khan, Huzefa A. Raja, Tyler N. Graf, Cedric J. Pearce, Nicholas H. Oberlies +2 more

Scaling up the production of fungal perylenequinones and investigating their biosynthesis through stable isotope labeling

Microbial Cell Factories(2025)10.1186/s12934-025-02842-6

N/A

0DataRank · unranked

1 citations

Sachin Dumbare, Tyler N. Graf, Warren S. Vidar, Huzefa A. Raja, Cedric J. Pearce +3 more

Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical In Vitro and In Vivo Models

Molecular Pharmaceutics(2023)10.1021/acs.molpharmaceut.3c00069

N/A

0DataRank · unranked

3 citations

Jaqueline Moraes Bazioli, Herma C. Pierre, Daniel D. Lantvit, Samuel K. Kulp, Kasey Hill +7 more

Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative Aspergillus fischeri

mBio(2020)10.1128/mbio.03361-19

N/A

0DataRank · unranked

52 citations

Matthew E. Mead, Lilian Pereira Silva, Huzefa A. Raja, Jacob L. Steenwyk, Gustavo H. Goldman +3 more

Bioactive diterpenoid metabolism and cytotoxic activities of genetically transformed Euphorbia lathyris roots

Phytochemistry(2020)10.1016/j.phytochem.2020.112504

N/A

0DataRank · unranked

14 citations

Vincent P. Sica, Sonja L. Knowles, N. Diette, Dianella G. Howarth, Nicholas H. Oberlies +1 more

Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage

Molecular Cancer Therapeutics(2020)10.1158/1535-7163.mct-19-0205

N/A

0DataRank · unranked

23 citations

Chiraz Soumia M. Amrine, Julia R. Austin, KiAundra Kilpatrick, Angela Russo, Daniel D. Lantvit +8 more

Phenethyisoquinoline alkaloids from the leaves of Androcymbium palaestinum

Fitoterapia(2020)10.1016/j.fitote.2020.104706

N/A

0DataRank · unranked

8 citations

Maram B. Alhawarri, José Rivera‐Chávez, Joanna E. Burdette, Austin Czarnecki, Mohammad Al‐Gharaibeh +5 more

Refined Prediction of Pharmacokinetic Kratom-Drug Interactions: Time-Dependent Inhibition Considerations

Journal of Pharmacology and Experimental Therapeutics(2020)10.1124/jpet.120.000270

N/A

0DataRank · unranked

36 citations

Dandan Tian, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel +2 more

Isolation and Identification of Intestinal CYP3A Inhibitors from Cranberry ( Vaccinium macrocarpon ) Using Human Intestinal Microsomes

NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro)(2020)10.17615/9fh3-xh98

N/A

0DataRank · unranked

3 citations

Tyler N. Graf, Scott J. Brantley, Arlene A. Sy‐Cordero, Eun‐Kyung Kim, Nicholas H. Oberlies +1 more

Nicholas H. Oberlies

Indexed papers

Top data-sharing exemplar

Papers