Paul G. Wyatt

Also affiliated with Drug Discovery Laboratory (Norway), Life Sciences Discovery Fund

MedicinePharmacology, Toxicology and PharmaceuticsBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 11 papers. Top paper: “PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis”.

PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis

Science(2020)10.1126/science.aav5912

N/A

0DataRank · unranked

206 citations

Helena I. Boshoff, Justin R. Harrison, Peter C. Ray, Simon R. Green, Paul G. Wyatt +2 more

The Tuberculosis Drug Accelerator at year 10: what have we learned?

Nature Medicine(2021)10.1038/s41591-021-01442-2

N/A

0DataRank · unranked

62 citations

David Barros-Aguirre, Clifton E. Barry, Robert H. Bates, Steven J. Berthel, Helena I. Boshoff +32 more

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01586

N/A

0DataRank · unranked

37 citations

Peter C. Ray, Fabio Zuccotto, Jorge Hernández, Anup Aggarwal, Claire J. Mackenzie +35 more

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth

ACS Omega(2021)10.1021/acsomega.0c05589

N/A

0DataRank · unranked

33 citations

Margaret Huggett, Penelope A. Turner, Malcolm Taylor, Laura A. T. Cleghorn, Julie V. Early +32 more

Antitubercular 2-Pyrazolylpyrimidinones: Structure–Activity Relationship and Mode-of-Action Studies

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.0c01727

N/A

0DataRank · unranked

21 citations

Vinayak Singh, Alissa Myrick, Sandile B. Simelane, Dale Taylor, Christel Brunschwig +21 more

Structure–Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents

ACS Infectious Diseases(2021)10.1021/acsinfecdis.0c00851

N/A

0DataRank · unranked

20 citations

M. Daben J. Libardo, Shaik Azeeza, Gary T. Pauly, José Santinni Roma, Andaleeb Sajid +10 more

Resistance of Mycobacterium tuberculosis to indole 4-carboxamides occurs through alterations in drug metabolism and tryptophan biosynthesis

Cell chemical biology(2021)10.1016/j.chembiol.2021.02.023

N/A

0DataRank · unranked

16 citations

Caroline J. Duncombe, Simon R. Green, Paul G. Wyatt, Stephen Thompson, Peter C. Ray +6 more

Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

Nature Communications(2021)10.1038/s41467-020-20224-x

N/A

0DataRank · unranked

17 citations

Simon R. Green, Joanna C. Evans, Jeannine Hess, M. Blasz̧czyk, Christina Spry +21 more

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs

Nature Communications(2022)10.1038/s41467-022-33736-5

N/A

0DataRank · unranked

34 citations

Susan H. Davis, Sebastian Damerow, Curtis A. Engelhart, Michael Mathieson, Beatriz Baragaña +40 more

Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01514

N/A

0DataRank · unranked

21 citations

Caroline Wilson, T.C. Eadsforth, Avinash S. Punekar, Fábio K. Tamaki, Gavin Wood +18 more

Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis

ACS Infectious Diseases(2025)10.1021/acsinfecdis.4c00808

N/A

0DataRank · unranked

4 citations

Justin R. Harrison, Stephen Thompson, Dinakaran Murugesan, M. Daben J. Libardo, Curtis A. Engelhart +18 more