David T. Breault

Also affiliated with Harvard University, Harvard Stem Cell Institute

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 48 papers. Top paper: “Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells”.

Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells

Gastroenterology(2023)10.1053/j.gastro.2023.02.030

N/A

0.652DataRank · unranked

76 citations

Peng Lei, Wenying Kang, Priscilla Cheung, Tao Xu, Miyeko Mana +20 more

Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction

Nature Biomedical Engineering(2022)10.1038/s41551-022-00899-x

N/A

0.648DataRank · unranked

74 citations

Cicely W. Fadel, Ben Swenor, Wuji Cao, Rani K. Powers, Diogo M. Camacho +16 more

Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells

Stem Cell Reports(2015)10.1016/j.stemcr.2015.09.006

N/A

0.571DataRank · unranked

44 citations

Alessio Tovaglieri, David T. Breault, Ramesh A. Shivdasani, Adrianna K. San Roman

A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine

Nature Communications(2022)10.1038/s41467-022-29085-y

N/A

0.557DataRank · unranked

40 citations

Christina M. Ferrer, Maria Paola Serra, Jee-Eun Choi, Nadia Ducano, Alessia Mira +20 more

Mislocalization of protein kinase A drives pathology in Cushing’s syndrome

Cell Reports(2022)10.1016/j.celrep.2022.111073

N/A

0.553DataRank · unranked

39 citations

Dominic P. Byrne, Kiana N. Jones, Tyler M. Lakey, Kerrie B. Collins, Kyung‐Soon Lee +15 more

Non-canonical Wnt signaling triggered by WNT2B drives adrenal aldosterone production

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.23.609423

N/A

0.389DataRank · unranked

11 citations

Donald W. Little, Taciani de Almeida Magalhães, Claudio Henrique T. Ribeiro, Typhanie Dumontet, Christopher R. LaPensee +17 more

Triple‐Decker Sandwich Cultures of Intestinal Organoids for Long‐Term Live Imaging, Uniform Perturbation, and Statistical Sampling

Current Protocols(2022)10.1002/cpz1.330

N/A

0.292DataRank · unranked

6 citations

Naren Tallapragada, Prabhath Mannam, David T. Breault, Allon M. Klein, Hailey M. Cambra

Abrogation of FGFR signaling blocks β-catenin–induced adrenocortical hyperplasia and aldosterone production

JCI Insight(2025)10.1172/jci.insight.184863

N/A

0.165DataRank · unranked

2 citations

Dulanjalee Kariyawasam, Mesut Berber, Nick A. Guagliardo, Sining Leng, Betül Haykir +10 more

WNT2B Deficiency Causes Increased Susceptibility to Colitis in Mice and Impairs Intestinal Epithelial Development in Humans

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.21.537894

N/A

0.165DataRank · unranked

2 citations

Sathuwarman Raveenthiraraj, Comfort Adegboye, Wanshu Qi, Radhika S. Khetani, Akaljot Singh +11 more

Human Mesofluidic Intestinal Model for Studying Transport of Drug Carriers and Bacteria Through a Live Mucosal Barrier

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.18.613692

N/A

0.104DataRank · unranked

1 citations

Hardeep S. Oberoi, Devalina Law, Yuan Li, Timothy Kassis, Linda G. Griffith +3 more

Innervated adrenomedullary microphysiological system to model nicotine and opioid exposure

Organs-on-a-Chip(2021)10.1016/j.ooc.2021.100009

N/A

0DataRank · unranked

5 citations

Gabriel Burchett, Ryan Brady, Kyla N. Nichols, David T. Breault, Abigail N. Koppes +2 more

Nutritional deficiency recapitulates intestinal injury associated with environmental enteric dysfunction in patient-derived Organ Chips

medRxiv(2021)10.1101/2021.10.11.21264722

N/A

0DataRank · unranked

5 citations

Cicely W. Fadel, Ben Swenor, Wuji Cao, Rani K. Powers, Diogo M. Camacho +16 more

Stiffness Regulates Intestinal Stem Cell Fate

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.15.435410

N/A

0DataRank · unranked

5 citations

Peng Lei, Wenying Kang, Priscilla Cheung, Tao Xu, Miyeko Mana +22 more

Stiffness Regulates Intestinal Stem Cell Fate

Research Square(2021)10.21203/rs.3.rs-362156/v1

N/A

0DataRank · unranked

1 citations

Peng Lei, Wenying Kang, Priscilla Cheung, Tao Xu, Miyeko Mana +22 more

Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.23.457340

N/A

0DataRank · unranked

0 citations

Gaya S. Dasanayake, Mary K. Estes, Nicholas C. Zachos, David T. Breault, Ralph R. Isberg +3 more

Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing’s syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.18.464848

N/A

0DataRank · unranked

0 citations

Dominic P. Byrne, Kiana N. Jones, Tyler M. Lakey, Kerrie B. Collins, Kyung‐Soon Lee +15 more

Robust differentiation of human enteroendocrine cells from intestinal stem cells

Nature Communications(2022)10.1038/s41467-021-27901-5

N/A

0DataRank · unranked

71 citations

Eric Stas, Joshua de Sousa Casal, Prabhath Mannam, Wanshu Qi, Xiaolei Yin +9 more

Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease

Gut(2022)10.1136/gutjnl-2021-326534

N/A

0DataRank · unranked

44 citations

Wei‐Ting Kuo, Feng Cao, Sandra D. Chánez-Paredes, Daniel Zeve, Prabhath Mannam +8 more

Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants

Nature Communications(2022)10.1038/s41467-022-33964-9

N/A

0DataRank · unranked

27 citations

Xiaozhe Xiong, Ji Zeng, Siyu Wang, Benjamin J.-M. Tremblay, Peng Chen +13 more

Intrinsic Adrenal TWIK-Related Acid-Sensitive TASK Channel Dysfunction Produces Spontaneous Calcium Oscillations Sufficient to Drive AngII (Angiotensin II)-Unresponsive Hyperaldosteronism

Hypertension(2022)10.1161/hypertensionaha.122.19557

N/A

0DataRank · unranked

11 citations

Molly R. Gerding, David T. Breault, Mark P. Beenhakker, Paula Q. Barrett, Nick A. Guagliardo +1 more

Telomerase Reverse Transcriptase Expression Marks a Population of Rare Adipose Tissue Stem Cells

Stem Cells(2022)10.1093/stmcls/sxab005

N/A

0DataRank · unranked

3 citations

Diana L. Carlone, Kristy L. Townsend, David T. Breault, Yu‐Hua Tseng, Matthew D. Lynes

Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens

Developmental Cell(2023)10.1016/j.devcel.2023.11.027

N/A

0DataRank · unranked

31 citations

Jingjing Liu, Charlene Chan, Kleiton Silva Borges, Jiuchun Zhang, Andrew J. Kane +10 more

RET Signaling Persists in the Adult Intestine and Stimulates Motility by Limiting PYY Release From Enteroendocrine Cells

Gastroenterology(2023)10.1053/j.gastro.2023.11.020

N/A

0DataRank · unranked

18 citations

Laurence Feinstein, Svetlana L. Sabel, Daniella Rastelli, Esther Mezhibovsky, Lynley Matthews +9 more

β-Catenin–Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer

Cancer Research(2023)10.1158/0008-5472.can-22-2712

N/A

0DataRank · unranked

16 citations

Kleiton Silva Borges, Isabella Finco, Christopher R. LaPensee, Juilee Rege, April L. Solon +25 more

An immune-competent human gut microphysiological system enables inflammation-modulation of Faecalibacterium prausnitzii

Research Square(2023)10.21203/rs.3.rs-3373576/v1

N/A

0DataRank · unranked

4 citations

Yu-Ja Huang, Martin Trapečar, Charles Wright, Kirsten Schneider, John Kemmit +7 more

Telomerase reverse transcriptase (TERT)-expressing cells mark a novel stem cell population in the adult mouse brain

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.09.527879

N/A

0DataRank · unranked

2 citations

Ashleigh N. Beaulieu, Caroline D. Curtis, Joshua Passarelli, Magdalena Blaszkiewicz, Seth Thomas +12 more

An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii

npj Biofilms and Microbiomes(2024)10.1038/s41522-024-00501-z

N/A

0DataRank · unranked

26 citations

Yu-Ja Huang, Martin Trapečar, Charles Wright, Kirsten Schneider, John Kemmitt +8 more

WNT2B Deficiency Causes Enhanced Susceptibility to Colitis Due to Increased Inflammatory Cytokine Production

Cellular and Molecular Gastroenterology and Hepatology(2024)10.1016/j.jcmgh.2024.04.006

N/A

0DataRank · unranked

12 citations

Sathuwarman Raveenthiraraj, Luiz Fernando Silva Oliveira, Comfort Adegboye, Venkata Siva Dasuri, Wanshu Qi +14 more

Gut tumors in flies alter the taste valence of an anti-tumorigenic bitter compound

Current Biology(2024)10.1016/j.cub.2024.04.082

N/A

0DataRank · unranked

9 citations

Chiwei Xu, Joshua Shing Shun Li, Anindya Ganguly, Geoff T. Meyerhof, Yannik Régimbald‐Dumas +6 more

Faecalibacterium prausnitzii A2-165 metabolizes host- and media-derived chemicals and induces transcriptional changes in colonic epithelium in GuMI human gut microphysiological system

Microbiome Research Reports(2024)10.20517/mrr.2024.14

N/A

0DataRank · unranked

5 citations

Caroline A. Lewis, Charles Wright, Kirsten Schneider, John Kemmitt, David L. Trumper +5 more

RELMβ sets the threshold for microbiome-dependent oral tolerance

Nature(2025)10.1038/s41586-024-08440-7

N/A

0DataRank · unranked

36 citations

Gavin A. Kuziel, Mónica Martínez‐Blanco, Bat‐Erdene Jugder, Mehdi Benamar, Ziwei Wang +20 more

Osmolarity Controls Oscillatory Calcium Signaling to Reduce Autonomous Aldosterone Production in Zona Glomerulosa Cells

Endocrinology(2025)10.1210/endocr/bqaf147

N/A

0DataRank · unranked

2 citations

Molly R. Gerding, David T. Breault, Edward H. Nieh, Mark P. Beenhakker, Paula Q. Barrett +2 more

Human mesofluidic intestinal model for studying transport of drug carriers and bacteria through a live mucosal barrier

Lab on a Chip(2025)10.1039/d4lc00774c

N/A

0DataRank · unranked

1 citations

Hardeep S. Oberoi, Devalina Law, Yuan Li, Timothy Kassis, Linda G. Griffith +3 more

Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids

Biomaterials(2020)10.1016/j.biomaterials.2020.120125

N/A

0DataRank · unranked

170 citations

Timothy Kassis, Arinola O. Lampejo, GiHun Choi, Mario E. Gamboa, Juan S. Gnecco +5 more

Hippo Signaling Is Essential for the Maintenance of Zona Glomerulosa Cell Fate in the Murine Adrenal Cortex

Endocrinology(2025)10.1210/endocr/bqaf077

N/A

0DataRank · unranked

1 citations

Natalia Jakuc, Marie-Charlotte Meinsohn, Laureline Charrier, Laurence Banville, Julie Brind’Amour +9 more

Mesenchymal WNT2B is required for the development and function of the human intestine

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.01.651727

N/A

0DataRank · unranked

0 citations

Holly M. Poling, Jennifer Foulke‐Abel, Nambirajan Sundaram, Abid A. Reza, Sarah Joseph +11 more

Loss of WNT2B Increases Progression from Dysplasia to Colorectal Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.21.671161

N/A

0DataRank · unranked

0 citations

Yu-Syuan Wu, Sathuwarman Raveenthiraraj, Jaedeok Kwon, Venkata Siva Dasuri, Comfort Adegboye +6 more

Human fetal small intestinal T cells induce epithelial growth and secretory lineage differentiation 2280

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.215

N/A

0DataRank · unranked

0 citations

Dhana Llivichuzhca-Loja, Wenjia Wang, Weihong Gu, Kerri St Denis, Eduardo Gonzalez Santiago +5 more

CXXC Finger Protein 1 drives BMP signaling and progenitor cell differentiation during limb development

Developmental Biology(2025)10.1016/j.ydbio.2025.09.004

N/A

0DataRank · unranked

1 citations

Lijie Jiang, Manasvi S. Shah, Anish Karpurapu, Ji Miao, Yangyang Liu +8 more

Primary Human Colonic Mucosal Barrier Crosstalk with Super Oxygen-Sensitive Faecalibacterium prausnitzii in Continuous Culture

Med(2020)10.1016/j.medj.2020.07.001

N/A

0DataRank · unranked

129 citations

Yu-Ja Huang, Jun Young Yoon, John Kemmitt, Charles Wright, Kirsten Schneider +17 more

Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation

Cell Reports(2020)10.1016/j.celrep.2020.107524

N/A

0DataRank · unranked

69 citations

Sining Leng, Yixing Yuchi, Kleiton Silva Borges, Nick A. Guagliardo, Manasvi S. Shah +8 more

Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes

Nature Communications(2020)10.1038/s41467-020-15408-4

N/A

0DataRank · unranked

58 citations

Peter Klein, Christina A. Gancayco, Adam C Lu, Sining Leng, Rany R. Makarem +6 more

Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice

Oncogene(2020)10.1038/s41388-020-1358-5

N/A

0DataRank · unranked

51 citations

Emanuele Pignatti, Sining Leng, Dulanjalee Kariyawasam, Gerard Ruiz‐Babot, Fernando Silva Ramalho +4 more

Rapid Prototyping of Multilayer Microphysiological Systems

ACS Biomaterials Science & Engineering(2020)10.1021/acsbiomaterials.0c00190

N/A

0DataRank · unranked

51 citations

Adam J. Bindas, Marissa Puzan, Will Lake, Jonathan R. Soucy, Fanny Zhou +5 more

Cholinergic Activation of Primary Human Derived Intestinal Epithelium Does Not Ameliorate TNF-α Induced Injury

Cellular and Molecular Bioengineering(2020)10.1007/s12195-020-00633-0

N/A

0DataRank · unranked

11 citations

Will Lake, Eric Stas, Ryan A. Koppes, David T. Breault, Shashi K. Murthy +2 more

Robust differentiation of human enteroendocrine cells from intestinal stem cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.21.303990

N/A

0DataRank · unranked

3 citations

Eric Stas, Joshua de Sousa Casal, Prabhath Mannam, Wanshu Qi, Xiaolei Yin +9 more

Primary human colonic mucosal barrier crosstalk with super oxygen-sensitive Faecalibacterium prausnitzii in continuous culture

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.02.185082

N/A

0DataRank · unranked

0 citations

Yu-Ja Huang, Jun–Young Yoon, John Kemmitt, Charles Wright, Kirsten Schneider +17 more

Rosette morphology in zona glomerulosa formation and function

Molecular and Cellular Endocrinology(2021)10.1016/j.mce.2021.111287

N/A

0DataRank · unranked

9 citations

Diana L. Carlone, Nick A. Guagliardo, Paula Q. Barrett, David T. Breault, Sining Leng