Francesc X. Ruiz

Rutgers, The State University of New Jersey

Also affiliated with Rutgers Sexual and Reproductive Health and Rights, Rütgers (Germany)

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.5Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.406637

Top 9%

2.5DataRank

Top 9%28 citations

Christine Zardecki, Elliott M. Dolan, Changpeng Lu, Zhuofan Shen, Shuchismita Dutta +59 more

Papers

Driven by 24 papers — median percentile 91. Top paper: “Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic”.

Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.406637

Top 9%

2.5DataRank

Top 9%28 citations

Christine Zardecki, Elliott M. Dolan, Changpeng Lu, Zhuofan Shen, Shuchismita Dutta +59 more

Structures, functions and adaptations of the human LINE-1 ORF2 protein

Nature(2023)10.1038/s41586-023-06947-z

N/A

0.728DataRank · unranked

127 citations

Trevor van Eeuwen, David Hoyos, Arthur O. Zalevsky, Egor P. Tchesnokov, Roberto Sánchez +40 more

Structure-Based Design of Covalent SARS-CoV-2 Papain-like Protease Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01872

N/A

0.501DataRank · unranked

12 citations

Xueying Liang, Ahmadullah Ansari, Prakash D. Jadhav, Haozhou Tan, Kan Li +5 more

Evolution of the SARS‐CoV‐2 proteome in three dimensions (3D) during the first 6 months of the COVID‐19 pandemic

Proteins Structure Function and Bioinformatics(2021)10.1002/prot.26250

N/A

0DataRank · unranked

49 citations

Christine Zardecki, Elliott M. Dolan, Changpeng Lu, Zhuofan Shen, Shuchismita Dutta +59 more

HIV-1 gp120 Antagonists Also Inhibit HIV-1 Reverse Transcriptase by Bridging the NNRTI and NRTI Sites

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01104

N/A

0DataRank · unranked

9 citations

Francesc X. Ruiz, Francesca Curreli, Kevin Gruber, Alyssa Pilch, Kalyan Das +3 more

Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)

Viruses(2021)10.3390/v13081495

N/A

0DataRank · unranked

6 citations

Steve Tuske, Kalyan Das, Francesc X. Ruiz, Joseph D. Bauman, Paul L. Boyer +4 more

Resolving the Dynamic Motions of SARS-CoV-2 nsp7 and nsp8 Proteins Using Structural Proteomics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.06.434214

N/A

0DataRank · unranked

5 citations

Sanjay Kumar Dey, Ruchi Yadav, Jennifer Timm, Jerry Joe Ebow Kingsley Harrison, Francesc X. Ruiz +3 more

Cryo-EM Structure of the Pol Polyprotein Provides Insights into HIV Maturation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.03.462959

N/A

0DataRank · unranked

2 citations

Dario Oliveira Passos, Jessica F. Bruhn, Joseph D. Bauman, Lynda Tuberty, Jeffrey J. DeStefano +4 more

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

Science Advances(2022)10.1126/sciadv.add2191

N/A

0DataRank · unranked

34 citations

Valentine V. Courouble, Sanjay Kumar Dey, Jerry Joe E.K. Harrison, Jennifer Timm, Jesse B. Hopkins +6 more

Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing

Drug Discovery Today(2022)10.1016/j.drudis.2022.02.016

N/A

0DataRank · unranked

9 citations

Anthony Hoang, Christopher R. Dilmore, Jeffrey J. DeStefano, Eddy Arnold, Francesc X. Ruiz

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.27.493767

N/A

0DataRank · unranked

1 citations

Valentine V. Courouble, Sanjay Kumar Dey, Jerry Joe E.K. Harrison, Jennifer Timm, Jesse B. Hopkins +6 more

The Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.17.512577

N/A

0DataRank · unranked

1 citations

Joseph D. Bauman, Francesc X. Ruiz, Eddy Arnold, Ashima Chopra

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors

Communications Chemistry(2023)10.1038/s42004-023-00888-4

N/A

0DataRank · unranked

25 citations

Boshi Huang, Shawn Rumrill, David Pople, Waleed A. Zalloum, Dongwei Kang +13 more

Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach

Molecules(2023)10.3390/molecules28073103

N/A

0DataRank · unranked

7 citations

Shawn Rumrill, Shane Dawson, Adam Johnson, Jo‐Anne Pinson, Menachem J. Gunzburg +13 more

Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.01.569653

N/A

0DataRank · unranked

5 citations

Xiaoming Zhang, Ahmadullah Ansari, Prakash D. Jadhav, Haozhou Tan, Kan Li +8 more

Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Science(2024)10.1126/science.adm9724

N/A

0DataRank · unranked

115 citations

Xiaoming Zhang, Ahmadullah Ansari, Prakash D. Jadhav, Haozhou Tan, Kan Li +8 more

Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates

Nature Communications(2025)10.1038/s41467-025-56902-x

N/A

0DataRank · unranked

24 citations

Xueying Liang, Ahmadullah Ansari, Bin Tan, Haozhou Tan, Kan Li +7 more

Structural basis for sirtuin 2 activity and modulation: Current state and opportunities

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110274

N/A

0DataRank · unranked

11 citations

Francesc X. Ruiz, Stacy Remiszewski, Matthew J. Todd, Thomas Shenk, John L. Kulp +2 more

Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles

Science Advances(2025)10.1126/sciadv.adt8916

N/A

0DataRank · unranked

6 citations

Shawn Rumrill, Dongwei Kang, Samuel Desta Guma, Da Feng, Erik De Clercq +7 more

Crystallographic Fragment Screening of the Dengue Virus Polymerase Reveals Multiple Binding Sites for the Development of Non-nucleoside Antiflavivirals

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01014

N/A

0DataRank · unranked

2 citations

J.C. Aschenbrenner, Francesc X. Ruiz, Ashima Chopra, Anu V. Chandran, Peter Marples +5 more

Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance

Current Opinion in Structural Biology(2020)10.1016/j.sbi.2019.11.011

N/A

0DataRank · unranked

81 citations

Eddy Arnold, Francesc X. Ruiz

Crystallographic fragment screening of the dengue virus polymerase reveals multiple binding sites for the development of non-nucleoside antiflavivirals

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.03.31.646453

N/A

0DataRank · unranked

1 citations

J.C. Aschenbrenner, Francesc X. Ruiz, Ashima Chopra, Anu V. Chandran, Peter Marples +5 more

Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer

Current Research in Structural Biology(2020)10.1016/j.crstbi.2020.06.002

N/A

0DataRank · unranked

18 citations

Jie Zheng, Erik D. Olson, Francesc X. Ruiz, Bruce D. Pascal, Anthony Hoang +7 more

Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.23.395087

N/A

0DataRank · unranked

0 citations

Steve Tuske, Kalyan Das, Francesc X. Ruiz, Joseph D. Bauman, Paul L. Boyer +4 more

Francesc X. Ruiz

Indexed papers

Top data-sharing exemplar

Papers