Thomas E. Edwards

Also affiliated with Amazon (United States), Joint Center for Structural Genomics, Beryllium (United States), Virginia Mason Bainbridge Island Medical Center

Materials ScienceBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 28 papers. Top paper: “New Structural Insights into the Function of the Active Full Length Human Taspase1: A Novel Anticancer Therapeutic Target”.

New Structural Insights into the Function of the Active Full Length Human Taspase1: A Novel Anticancer Therapeutic Target

Biophysical Journal(2020)10.1016/j.bpj.2019.11.410

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1 citations

Nirupa Nagaratnam, Darren Thifault, S.L. Delker, Michele A. Zacks, Thomas E. Edwards +10 more

New Structural Insights into the Function of the Catalytically Active Human Taspase1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.26.400622

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0 citations

S.L. Delker, Rebecca Jernigan, Thomas E. Edwards, Janey Snider, Darren Thifault +9 more

Structural characterization of a GNAT family acetyltransferase from Elizabethkingia anophelis bound to acetyl-CoA reveals a new dimeric interface

Scientific Reports(2021)10.1038/s41598-020-79649-5

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20 citations

Seyed Mohammad Ghafoori, R. M. Irwin, Jan Abendroth, Stephen J. Mayclin, D. Lorimer +3 more

Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1

Scientific Reports(2021)10.1038/s41598-021-88672-z

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12 citations

Alyssa M. Robles, Angelika Arada, Paniz Shirmast, David M. Dranow, Stephen J. Mayclin +6 more

Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module

Microorganisms(2021)10.3390/microorganisms9081645

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9 citations

Tjaart de Beer, Stefanie Tamegger, Alexander Harms, Nikolaus Dietz, David M. Dranow +5 more

Structures of plasmepsin X from P. falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.24.460453

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0 citations

Anuradha Deshmukh, Nikhil Pahelkar, Abhishek B. Suryawanshi, Ishan Rathore, Vandana Mishra +11 more

Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme

Protein Science(2022)10.1002/pro.4279

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27 citations

Anuradha Deshmukh, Nikhil Pahelkar, Abhishek B. Suryawanshi, Ishan Rathore, Vandana Mishra +11 more

Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204473119

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24 citations

Allison Maker, Andrew Vae Priest, David M. Dranow, Jenny N. Phan, Thomas E. Edwards +5 more

Structure–Kinetic Relationship Studies for the Development of Long Residence Time LpxC Inhibitors

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00974

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21 citations

Yong Li, Suyuan Tao, Fereidoon Daryaee, Jonathan Merino, Chendi Gu +6 more

Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography

PNAS Nexus(2022)10.1093/pnasnexus/pgac163

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20 citations

Madison Bolejack, Leslayann Schecterson, Brad Hammerson, Jan Abendroth, Thomas E. Edwards +4 more

Structural characterization of aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa and Neisseria gonorrhoeae

Scientific Reports(2022)10.1038/s41598-022-17384-9

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10 citations

James W. Fairman, Marvin M Muruthi, Jan Abendroth, David M. Dranow, D. Lorimer +4 more

Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx

Acta Crystallographica Section F Structural Biology Communications(2022)10.1107/s2053230x22002138

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1 citations

Bart L. Staker, Sandhya Subramanian, Jan Abendroth, Thomas E. Edwards, Peter J. Myler +3 more

Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.06.483190

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1 citations

Allison Maker, Andrew Vae Priest, David M. Dranow, Jenny N. Phan, Thomas E. Edwards +5 more

Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site

Scientific Reports(2023)10.1038/s41598-023-33529-w

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23 citations

Gayle F. Petersen, Deborah G. Conrady, Brandy Calhoun, Matthew Z. Z. Stigliano, Ruth Baydo +6 more

New therapeutic strategies for Mycobacterium abscessus pulmonary diseases – untapping the mycolic acid pathway

Expert Review of Anti-infective Therapy(2023)10.1080/14787210.2023.2224563

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16 citations

Thomas E. Edwards, Laurent Kremer, Matthéo Alcaraz

In Vitro and In Vivo Efficacy of NITD-916 against Mycobacterium fortuitum

Antimicrobial Agents and Chemotherapy(2023)10.1128/aac.01607-22

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12 citations

Matthéo Alcaraz, Claire Hamela, Jan Abendroth, Thomas E. Edwards, Laurent Kremer +1 more

Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1

Acta Crystallographica Section F Structural Biology Communications(2023)10.1107/s2053230x23008002

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6 citations

Yagmur Konuk, Jordan O. Norman, Jan Abendroth, Thomas E. Edwards, Donald D. Lorimer +9 more

Structure-Guided Discovery of N5-CAIR Mutase Inhibitors

Biochemistry(2023)10.1021/acs.biochem.2c00705

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3 citations

Nandini Sharma, Rachael Zigweid, Madison Bolejack, Doug Davies, Thomas E. Edwards +3 more

Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6

Structure(2024)10.1016/j.str.2024.05.001

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3 citations

John V. Dzimianski, Meng Yang, Jan Abendroth, Giuseppe A. Sautto, Ted M. Ross +4 more

Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens

Communications Biology(2024)10.1038/s42003-024-07175-5

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4 citations

Phillip G. Pierce, Jan Abendroth, Kayleigh F. Barrett, Lynn K. Barrett, Kalinga Bowatte +28 more

Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis

Acta Crystallographica Section F Structural Biology Communications(2024)10.1107/s2053230x2400356x

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3 citations

Prashit Parikh, Jan Abendroth, T.L. Arakaki, Matthew C. Clifton, Thomas E. Edwards +6 more

Crystal structure of glutamyl-tRNA synthetase from Helicobacter pylori

Acta Crystallographica Section F Structural Biology Communications(2024)10.1107/s2053230x24011099

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2 citations

Jesuferanmi P. Ayanlade, David T. Laseinde, Sandhya Subramanian, Hannah S. Udell, Donald D. Lorimer +5 more

Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis

Acta Crystallographica Section F Structural Biology Communications(2024)10.1107/s2053230x24000621

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0 citations

Brian E. Hartnett, Tosha M. Laughlin, Joy M. Blain, Stephen J. Mayclin, Madison Bolejack +10 more

The crystal structures of apo and tryptophan-bound tryptophanyl-tRNA synthetase from Neisseria gonorrhoeae

Acta Crystallographica Section F Structural Biology Communications(2025)10.1107/s2053230x25001311

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2 citations

David Song, Thomas E. Edwards, David M. Dranow, Donald D. Lorimer, Bart L. Staker +3 more

Structural and kinetic analysis of distinct active and inactive states of Burkholderia cenocepacia orotate phosphoribosyltransferase

Archives of Biochemistry and Biophysics(2025)10.1016/j.abb.2025.110332

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1 citations

Zachary R. Turlington, Sean P. Zupko, Michael N Catoggio, Christine Lukacs, Dmitry Serbzhinskiy +12 more

Architecture of Pseudomonas aeruginosa glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2504757122

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0 citations

Stephen J. Mayclin, Steve Seibold, Amy E. DeRocher, Sandhya Subramanian, Isabelle Phan +16 more

Crystal structure of a complete threonyl tRNA synthetase: toggle clamp model?

Biochemical and Biophysical Research Communications(2025)10.1016/j.bbrc.2025.152677

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0 citations

Michael K. Fenwick, Thomas E. Edwards, David M. Dranow, Jan Abendroth, Roger Shek +5 more

Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD + -bound protomer chains

Acta Crystallographica Section F Structural Biology Communications(2025)10.1107/s2053230x25009227

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0 citations

Amelia T. Konstanty, Stephen J. Mayclin, Ryan Choi, Dmitry Serbzhinskiy, E. Cubero Robles +9 more