Masoud Vedadi

Also affiliated with University of Toronto

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 39 papers. Top paper: “Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation”.

Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation

ACS Medicinal Chemistry Letters(2020)10.1021/acsmedchemlett.0c00193

N/A

1.7DataRank · unranked

36 citations

Yihang Jing, Supuni Thalalla Gamage, Kathryn M. Nelson, Joseph Han, Keri M. Bryson +17 more

Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00406

N/A

0DataRank · unranked

42 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halabelian, Kwang‐Su Park, Irene Chau +11 more

Optimization of Cellular Activity of G9a Inhibitors 7-Aminoalkoxy-quinazolines

Figshare(2020)10.17615/66q8-7d37

N/A

0DataRank · unranked

5 citations

Masoud Vedadi, Peter J. Brown, Jian Jin, Stephen V. Frye, Abdellah Allali‐Hassani +8 more

Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines.

INDIGO (University of Illinois at Chicago)(2020)10.17615/0ecj-ye88

N/A

0DataRank · unranked

5 citations

C.H. Arrowsmith, Irene Chau, Guillermo Senisterra, Masoud Vedadi, Jian Jin +16 more

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

Figshare(2020)10.17615/q3bp-3c89

N/A

0DataRank · unranked

3 citations

Feng Liu, Masoud Vedadi, Kyle D. Konze, C.H. Arrowsmith, Gang Greg Wang +18 more

Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.25.398586

N/A

0DataRank · unranked

5 citations

Yanli Liu, Magdalena M. Szewczyk, Naimee Mehta, Fengling Li, David McLeod +14 more

A First-in-class, Highly Selective and Cell-active Allosteric Inhibitor of Protein Arginine Methyltransferase 6 (PRMT6)

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.04.412569

N/A

0DataRank · unranked

1 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halebelian, Irene Chau, Mohammad S. Eram +19 more

A chemical tool for chemiprecipitation of the lysine methyltransferase, G9a, in vitro and in vivo

UNC Libraries(2020)10.17615/d4tj-7d15

N/A

0DataRank · unranked

0 citations

Fengling Li, Ian J. Davis, Jian Jin, Dalia Barsyte-Lovejoy, Feng Liu +4 more

A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

UNC Libraries(2020)10.17615/s278-v194

N/A

0DataRank · unranked

0 citations

Luo Xiao, Magdalena M. Szewczyk, Masoud Vedadi, Aiping Dong, David Smil +24 more

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

UNC Libraries(2020)10.17615/h6h3-eh02

N/A

0DataRank · unranked

0 citations

Peter A. DiMaggio, Dalia Barsyte-Lovejoy, Sylvie Rival‐Gervier, W. Tempel, Feng Liu +27 more

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

Nature Chemical Biology(2021)10.1038/s41589-021-00898-0

N/A

0DataRank · unranked

109 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +35 more

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

SLAS DISCOVERY(2021)10.1177/24725552211026261

N/A

0DataRank · unranked

89 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions

Nucleic Acids Research(2021)10.1093/nar/gkab460

N/A

0DataRank · unranked

74 citations

J.R. Horton, Jie Yang, Taraneh Hajian, Masoud Vedadi, Cari A. Sagum +5 more

A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells

Cell chemical biology(2021)10.1016/j.chembiol.2021.08.004

N/A

0DataRank · unranked

62 citations

Fanye Meng, Kwang‐Su Park, Aaron J. Storey, Weida Gong, Yi‐Hsuan Tsai +12 more

Development of LM98, a Small‐Molecule TEAD Inhibitor Derived from Flufenamic Acid

ChemMedChem(2021)10.1002/cmdc.202100432

N/A

0DataRank · unranked

34 citations

Shuay Abdullayev, Ahmed Fnaiche, Victoria Vu, Narjara González Suárez, Hong Zeng +15 more

A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.0c02160

N/A

0DataRank · unranked

27 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halabelian, Irene Chau, Mohammad S. Eram +22 more

Discovery of an in Vivo Chemical Probe of the Lysine Methyltransferases G9a and GLP

INDIGO (University of Illinois at Chicago)(2021)10.17615/s98d-vh37

N/A

0DataRank · unranked

9 citations

Abdellah Allali‐Hassani, Victoria Korboukh, Jian Jin, Xi‐Ping Huang, Masoud Vedadi +9 more

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

UCL Discovery (University College London)(2021)10.33774/chemrxiv-2021-rzq4n

N/A

0DataRank · unranked

13 citations

Rima Al‐awar, Rommie E. Amaro, C.H. Arrowsmith, Hátylas Azevedo, Robert A. Batey +34 more

Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.19.424337

N/A

0DataRank · unranked

11 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.05.433782

N/A

0DataRank · unranked

3 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +29 more

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

ChemRxiv(2021)10.26434/chemrxiv-2021-rzq4n

N/A

0DataRank · unranked

0 citations

Rima Al‐awar, Rommie E. Amaro, C.H. Arrowsmith, Hátylas Azevedo, Robert A. Batey +34 more

Small-molecule ligands of methyl-lysine binding proteins: Optimization of selectivity for L3MBTL3

Figshare(2021)10.17615/x6qe-4112

N/A

0DataRank · unranked

0 citations

Masoud Vedadi, Lindsey A. Ingerman, Robert Lam, Victoria Korboukh, J. Martin Herold +11 more

Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c01789

N/A

0DataRank · unranked

10 citations

J.R. Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu +12 more

Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2

Journal of the American Chemical Society(2023)10.1021/jacs.3c01421

N/A

0DataRank · unranked

64 citations

David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu +14 more

Discovery of Nanomolar DCAF1 Small Molecule Ligands

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c02132

N/A

0DataRank · unranked

63 citations

Serah Kimani, Brian J. Wilson, Mahmoud Noureldin, Héctor González-Álvarez, Ahmed Mamai +29 more

Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c02120

N/A

0DataRank · unranked

48 citations

Fengling Li, Elissa A. Fink, Irene Chau, Alice Shi Ming Li, Annia Rodríguez‐Hernández +18 more

The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition

Communications Biology(2023)10.1038/s42003-023-05655-8

N/A

0DataRank · unranked

33 citations

Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li +9 more

Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors

ACS Omega(2023)10.1021/acsomega.3c02815

N/A

0DataRank · unranked

28 citations

Dominika Chalupská, Karel Chalupský, Michala Zgarbová, Alexandra Dvořáková, Petra Krafčíková +12 more

Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00203

N/A

0DataRank · unranked

22 citations

Ján Kozic, Fengling Li, Mónica Rosas‐Lemus, G. Minasov, Jiří Rybáček +19 more

SETD7 functions as a transcription repressor in prostate cancer via methylating FOXA1

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220472120

N/A

0DataRank · unranked

15 citations

Jessica Petricca, Mingyu Liu, Songqi Zhang, Sujun Chen, Muqing Li +12 more

Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase

ACS Chemical Biology(2023)10.1021/acschembio.3c00035

N/A

0DataRank · unranked

7 citations

Youchao Deng, Iredia D. Iyamu, J.R. Horton, Dan Yu, Taraneh Hajian +8 more

Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors

RSC Medicinal Chemistry(2023)10.1039/d2md00149g

N/A

0DataRank · unranked

4 citations

Jeanne Chiavaralli, Afnan Hassan, Loay Bedda, Tim Krischuns, Kuang‐Yu Chen +10 more

Probing the mechanism of Cbl-b inhibition by a small-molecule inhibitor

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.05.539612

N/A

0DataRank · unranked

3 citations

Sumera Perveen, Magdalena Szewezyk, Hong Zeng, Aiping Dong, Fengling Li +9 more

Structure-based discovery of inhibitors of the SARS-CoV-2 Nsp14 N7 -methyltransferase

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.12.523677

N/A

0DataRank · unranked

2 citations

Fengling Li, Elissa A. Fink, Irene Chau, Alice Li, Annia Rodríguez‐Hernández +18 more

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.03.560722

N/A

0DataRank · unranked

2 citations

Matthew F. D. Hurley, Fengling Li, Eva Konkoľová, Martin Klíma, Jana Trylčová +21 more

Kinetic characterization of human mRNA guanine-N7 methyltransferase

Scientific Reports(2024)10.1038/s41598-024-55184-5

N/A

0DataRank · unranked

8 citations

Aliakbar Khalili Yazdi, Taraneh Hajian, Fengling Li, Masoud Vedadi, Sumera Perveen

Application of established computational techniques to identify potential SARS-CoV-2 Nsp14-MTase inhibitors in low data regimes

Digital Discovery(2024)10.1039/d4dd00006d

N/A

0DataRank · unranked

9 citations

Matthew F. D. Hurley, Fengling Li, Eva Konkoľová, Martin Klíma, Jana Trylčová +21 more

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Nature Communications(2020)10.1038/s41467-020-16271-z

N/A

0DataRank · unranked

108 citations

Yoshinori Ishikawa, Shawna Organ, Nozomu Sakai, Fengling Li, Levon Halabelian +26 more

Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00121

N/A

0DataRank · unranked

3 citations

Holger Greschik, C. Johansson, Ludwig Seifert, Vicki Gamble, Kwang‐Su Park +14 more