John S. Lazo

Also affiliated with University of Virginia

Social SciencesMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 18 papers. Top paper: “A three-dimensional dementia model reveals spontaneous cell cycle re-entry and a senescence-associated secretory phenotype”.

A three-dimensional dementia model reveals spontaneous cell cycle re-entry and a senescence-associated secretory phenotype

Neurobiology of Aging(2020)10.1016/j.neurobiolaging.2020.02.011

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16 citations

Shahzad S. Khan, Erin P. Foff, M. Murat Köseoğlu, Isabella K. Blanco, Sruthi Jayaraman +6 more

Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin

Molecular Pharmacology(2020)10.1124/molpharm.120.000131

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12 citations

Adam Boulton, Ettore J. Rastelli, Nikhil R. Tasker, Taber S. Maskrey, Isabella K. Blanco +7 more

A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity

UNC Libraries(2020)10.17615/1me1-w560

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0 citations

Heidi Dodson, John S. Lazo, James C. Morris, Kuo‐Hsiung Lee, Yoshiki Kashiwada +6 more

Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer

Biomolecules(2021)10.3390/biom11070969

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17 citations

Elizabeth R. Sharlow, Robert Cornelison, Duncan J. Hart, Danielle C. Llaneza, Anna J. Mendelson +5 more

Single intratracheal exposure to SARS‐CoV‐2 S1 spike protein induces acute lung injury in K18‐hACE2 transgenic mice

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.04183

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3 citations

Ruben Colunga Biancatelli, Elizabeth R. Sharlow, John S. Lazo, John D. Catravas, Pavel Solopov

Combination of Subtherapeutic Doses of Tretazicar and Liposomal Amphotericin B Suppresses and Cures Leishmania major-Induced Cutaneous Lesions in Murine Models

ACS Infectious Diseases(2021)10.1021/acsinfecdis.0c00886

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7 citations

Richard J. Sciotti, Jason Sousa, Brian A. Vesely, Tesfaye Teshome, Gustave Bonkoungou +10 more

Synthesis and evaluation of bifunctional PTP4A3 phosphatase inhibitors activating the ER stress pathway

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.128167

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7 citations

Sara Sannino, Duncan J. Hart, Elizabeth R. Sharlow, John S. Lazo, Jeffrey L. Brodsky +2 more

Extracellular cues accelerate neurogenesis of induced pluripotent stem cell derived neurons

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.17.456634

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5 citations

Danielle C. Llaneza, Anna J. Mendelson, Garnett A. Mingledorff, Veronica M. Porterfield, Kathryn A. Salvati +4 more

Transcriptional and translational regulation of pathogenesis in Alzheimer’s disease model mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.17.460831

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0 citations

Elizabeth R. Sharlow, John S. Lazo, George S. Bloom, José Sotelo‐Silveira, Guillermo Eastman

High content screening miniaturization and single cell imaging of mature human feeder layer-free iPSC-derived neurons

SLAS DISCOVERY(2022)10.1016/j.slasd.2022.10.002

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2 citations

Danielle C. Llaneza, William E. Grever, Garnett A. Mingledorff, Anna J. Mendelson, George S. Bloom +2 more

Deactivation of STAT3 and ERK and Activation of p38 in Ovarian Cancer Cells Treated with a Small Molecule Inhibitor of PTP4A3 Phosphatase

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2345

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0 citations

Kelly N. Isbell, Ettore J. Rastelli, Peter Wipf, Elizabeth R. Sharlow, John S. Lazo

Disruption of Ovarian Cancer STAT3 and p38 Signaling with a Small-Molecule Inhibitor of PTP4A3 Phosphatase

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.001401

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11 citations

Kelly N. Isbell, Sai Ashish Vasa, Danielle C. Llaneza, Ettore J. Rastelli, Peter Wipf +2 more

An acute respiratory distress syndrome drug development collaboration stimulated by the Virginia Drug Discovery Consortium

SLAS DISCOVERY(2023)10.1016/j.slasd.2023.02.001

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5 citations

Ruben M. L. Colunga-Biancatelli, Pavel Solopov, John D. Catravas, John S. Lazo

Pharmacological profiling identifies divergent chemosensitivities of differentiating and maturingiPSC‐derived human cortical neuron populations

FEBS Journal(2023)10.1111/febs.16901

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1 citations

Danielle C. Llaneza, Bhanu P. Tewari, Garnett A. Mingledorff, Anna J. Mendelson, Harald Sontheimer +3 more

Data from Improved low molecular weight Myc-Max inhibitors

(2023)10.1158/1535-7163.c.6531897

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0 citations

Dalia I. Hammoudeh, Ariele Viacava Follis, Brian E. Reese, John S. Lazo, Steven J. Metallo +2 more

Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities

Biomolecules(2024)10.3390/biom14070819

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3 citations

Heather Donald, Mounia Alaoui-El-Azher, John Skoko, John S. Lazo, Michael A. Parniak +3 more

Deletion of PTP4A3 phosphatase in high-grade serous ovarian cancer cells decreases tumorigenicity and produces marked changes in intracellular signaling pathways and cytokine release

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.124.002110

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3 citations

Kelly N. Isbell, Sai Ashish Vasa, Danielle C. Llaneza, Garnett A. Mingledorff, Elizabeth R. Sharlow +1 more

The PTP4A3 inhibitor KVX-053 reduces Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virulence, inflammation, and development of acute lung injury in K18-hACE2 mice

Respiratory Research(2025)10.1186/s12931-025-03349-9

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2 citations

Pavel Solopov, Caitlin Woodson, Irving C. Allen, Ivan Akhrymuk, Maryna Akhrymuk +9 more