David P. Siderovski

Also affiliated with University of North Texas Health Science Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 56 papers. Top paper: “G-protein signaling: back to the future”.

G-protein signaling: back to the future

UNC Libraries(2020)10.17615/80cw-5434

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0DataRank · unranked

30 citations

Francis S. Willard, Christopher R. McCudden, David P. Siderovski, Melinda D. Hains, Randall J. Kimple

Regulation of T cell activation, anxiety, and male aggression by RGS2

UNC Libraries(2020)10.17615/smne-6m58

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17 citations

S. Mariathasan, J. C. Roder, Josef Penninger, I. Q. Whishaw, A. J. Oliveira-dos-Santos +9 more

Genome-Scale Analysis Reveals Sst2 as the Principal Regulator of Mating Pheromone Signaling in the Yeast Saccharomyces cerevisiae

UNC Libraries(2020)10.17615/w9wn-k076

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4 citations

H. G. Dohlman, S. C. Parnell, P. Flanary, not provided Shijie Hao, J. Y. Cha +2 more

Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity

UNC Libraries(2020)10.17615/rdmr-wt60

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4 citations

David P. Siderovski, A. J. Kimple, S. Kuravi, N. A. Lambert, C. A. Johnston +2 more

Regulators of G-Protein Signaling and Their G Substrates: Promises and Challenges in Their Use as Drug Discovery Targets

UNC Libraries(2020)10.17615/3tge-9q27

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3 citations

D. E. Bosch, A. J. Kimple, David P. Siderovski, P. M. Giguere

Leukemia-Associated Rho Guanine Nucleotide Exchange Factor Promotes G q-Coupled Activation of RhoA

UNC Libraries(2020)10.17615/c0kz-4058

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2 citations

M. A. Booden, David P. Siderovski, C. J. Der

Clathrin Adaptor AP2 Regulates Thrombin Receptor Constitutive Internalization and Endothelial Cell Resensitization

UNC Libraries(2020)10.17615/gqcp-0z69

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2 citations

J. Trejo, M. M. Paing, C. A. Johnston, David P. Siderovski

Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin

Figshare(2020)10.17615/cnft-0658

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2 citations

David P. Siderovski, Bing Yang, Dustin E. Bosch

Entamoeba histolytica RacC Selectively Engages p21-Activated Kinase Effectors

Figshare(2020)10.17615/2b57-4604

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1 citations

Dustin E. Bosch, David P. Siderovski

Rgs1 regulates multiple Gα subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism

UNC Libraries(2020)10.17615/e5gr-fv09

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1 citations

Angayarkanni Suresh, David P. Siderovski, Francis S. Willard, Naweed I. Naqvi, Hao Liu +1 more

A bifunctional Gα i /Gα s modulatory peptide that attenuates adenylyl cyclase activity

UNC Libraries(2020)10.17615/dhey-h633

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1 citations

Christopher A. Johnston, Rainer Blaesius, J. Kevin Ramer, Zoey L. Fredericks, David P. Siderovski +1 more

A P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis

UNC Libraries(2020)10.17615/msmk-hr43

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0 citations

Francis S. Willard, David P. Siderovski, Naweed I. Naqvi, Ravikrishna Ramanujam, Adam J. Kimple +2 more

Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein α Subunit Mutants

UNC Libraries(2020)10.17615/n9sj-7249

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Deanne W. Sammond, Francis S. Willard, Adam J. Kimple, Mischa Machius, Michael J. Miley +4 more

PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

UNC Libraries(2020)10.17615/nngg-g171

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David P. Siderovski, Gary L. Johnson, Kazuhiro Nakamura, Adam J. Kimple

A Homogeneous Method to Measure Nucleotide Exchange by α-Subunits of Heterotrimeric G-Proteins Using Fluorescence Polarization

UNC Libraries(2020)10.17615/s775-6d45

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0 citations

Klara R. Klein, David P. Siderovski, Robin E. Muller, Stephanie Q. Hutsell, Adam J. Kimple

G Protein Signaling Modulator-3 Inhibits the Inflammasome Activity of NLRP3

UNC Libraries(2020)10.17615/x1hc-bb79

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0 citations

Brian K. Buckley, Geneviève Laroche, Patrick M. Giguère, Justin E. Wilson, Ejiofor Ezekwe +5 more

Regulation of the Subcellular Localization of the G-protein Subunit Regulator GPSM3 through Direct Association with 14-3-3 Protein

UNC Libraries(2020)10.17615/ngqq-3b41

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0 citations

Geneviève Laroche, Joseph A. Duncan, Patrick M. Giguère, Emily A. Oestreich, David P. Siderovski

Structure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding Affinities

UNC Libraries(2020)10.17615/2h87-gp22

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0 citations

Carrie Purbeck, David P. Siderovski, Deanne W. Sammond, Brian Kuhlman, Randall J. Kimple +1 more

Structure of Gαi1 Bound to a GDP-Selective Peptide Provides Insight into Guanine Nucleotide Exchange

UNC Libraries(2020)10.17615/dy5d-v834

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0 citations

Mark R. Jezyk, David P. Siderovski, T. Kendall Harden, Francis S. Willard, Val J. Watts +7 more

A High Throughput Fluorescence Polarization Assay for Inhibitors of the GoLoco Motif/G-alpha Interaction

UNC Libraries(2020)10.17615/g5ha-5183

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David P. Siderovski, Anton Simeonov, Ajit Jadhav, Mark Hughes, Adam J. Kimple +6 more

Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica

UNC Libraries(2020)10.17615/59nz-8c27

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0 citations

Dustin E. Bosch, David P. Siderovski

G-protein Signaling Modulator-3 Regulates Heterotrimeric G-protein Dynamics through Dual Association with Gβ and Gα i Protein Subunits

UNC Libraries(2020)10.17615/jv8g-c579

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0 citations

Geneviève Laroche, Patrick M. Giguère, David P. Siderovski, Emily A. Oestreich

Unique Structural and Nucleotide Exchange Features of the Rho1 GTPase of Entamoeba histolytica

UNC Libraries(2020)10.17615/21yz-4y96

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0 citations

Erika S. Wittchen, Connie Qiu, Dustin E. Bosch, Keith Burridge, David P. Siderovski

A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

UNC Libraries(2020)10.17615/v2fh-k627

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0 citations

David P. Siderovski, David K. Worthylake, John Sondek, Jason T. Snyder, Kent L. Rossman +1 more

Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation

UNC Libraries(2020)10.17615/x3ev-wc84

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0DataRank · unranked

0 citations

David P. Siderovski, Steven D. Cappell, Melinda D. Willard, Xiaoyan Li, William D. Snider +1 more

A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS*S

UNC Libraries(2020)10.17615/5g3b-6360

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0 citations

Zheng Zhen, Stephen R. Ikeda, Val J. Watts, Christopher A. Johnston, David P. Siderovski +9 more

A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation

UNC Libraries(2020)10.17615/jh9f-q113

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0 citations

Pradip Raychaudhuri, Matthew D. Smith, Zhengyu Zha, Qun‐Ying Lei, Kun‐Liang Guan +6 more

Regulator of G-protein Signaling-21 (RGS21) Is an Inhibitor of Bitter Gustatory Signaling Found in Lingual and Airway Epithelia

UNC Libraries(2020)10.17615/7ahs-8h83

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0 citations

Staci P. Cohen, Dustin E. Bosch, Francis S. Willard, Alaina L. Garland, David P. Siderovski +8 more

Crystal structure of the multifunctional Gβ5–RGS9 complex

UNC Libraries(2020)10.17615/y9kb-4m80

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Svetlana Gershburg, Jason T. Snyder, Matthew L. Cheever, John Sondek, T. Kendall Harden +1 more

Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica

UNC Libraries(2020)10.17615/hz44-4q18

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0DataRank · unranked

0 citations

Adam J. Kimple, Brenda Temple, Francis S. Willard, David P. Siderovski, Dustin E. Bosch +3 more

The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

UNC Libraries(2020)10.17615/8mwc-2x45

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0 citations

Xian Chen, Lei Yu, Blossom Damania, Lu Zhang, Babak Razani +12 more

Structural Determinants Underlying the Temperature-sensitive Nature of a Gα Mutant in Asymmetric Cell Division of Caenorhabditis elegans

UNC Libraries(2020)10.17615/zmpr-8045

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0 citations

David P. Siderovski, Francis S. Willard, Pierre Gönczy, Jason T. Snyder, Katayoun Afshar +2 more

Regulator of G-Protein Signaling 14 (RGS14) Is a Selective H-Ras Effector

UNC Libraries(2020)10.17615/b25a-0815

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0DataRank · unranked

0 citations

Randall J. Kimple, Xiaoyan Li, Emily A. Oestreich, Melinda D. Willard, Mark J. Zylka +8 more

RGS21, A Regulator of Taste and Mucociliary Clearance?

UNC Libraries(2020)10.17615/6pyt-kv91

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0 citations

Thomas P. Zielinski, Francis S. Willard, Alaina L. Garland, Vincent Setola, Robert G. Lowery +4 more

Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/870j-s815

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0 citations

Robin E. Muller, Alyssa J. Manning, Mischa Machius, David P. Siderovski, Stephen L. Rogers +3 more

Two Gα i1 Rate-Modifying Mutations Act in Concert to Allow Receptor-Independent, Steady-State Measurements of RGS Protein Activity

UNC Libraries(2020)10.17615/4myy-ad82

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0 citations

Thomas P. Zielinski, David P. Siderovski, Stephanie Q. Hutsell, Mark D. Koeff, Adam J. Kimple +1 more

Inhibition of Dopamine Transporter Activity by G Protein βγ Subunits

UNC Libraries(2020)10.17615/tr39-e189

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0 citations

Jennie García‐Olivares, Jun Zhu, Gonzalo E. Torres, William A. Owens, David P. Siderovski +4 more

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein -subunits

UNC Libraries(2020)10.17615/y5hr-jx59

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0 citations

A. J. Kimple, David P. Siderovski, O. Y. Fedorov, D. A. Doyle, G. A. Schoch +9 more

Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gα i Subunits † , ‡

Figshare(2020)10.17615/1dz7-4k66

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Suraj Adhikary, Heidi E. Hamm, David P. Siderovski, Michael A. Funk, William M. Oldham +5 more

Computational Design of the Sequence and Structure of a Protein-Binding Peptide

INDIGO (University of Illinois at Chicago)(2020)10.17615/jew7-ca23

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0 citations

Deanne W. Sammond, Brian Kuhlman, David P. Siderovski, Glenn L. Butterfoss, Dustin E. Bosch +2 more

Structural Determinants of G-protein α Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)

UNC Libraries(2020)10.17615/fvc2-w539

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0 citations

Brenda Temple, Stefan Knapp, A.K. Roos, Francis S. Willard, Bryan L. Roth +6 more

G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis

UNC Libraries(2020)10.17615/8wt8-wt88

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0 citations

Patrick M. Giguère, David P. Siderovski, Peng Liu, Matthew J. Billard, Teresa K. Tarrant +6 more

Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif

UNC Libraries(2020)10.17615/d9gb-5w84

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0 citations

Francis S. Willard, Gift K. NWEKE, David P. Siderovski, Melinda D. Hains, Miller B. Jones +1 more

Dynamic Regulation of Mammalian Numb by G Protein-coupled Receptors and Protein Kinase C Activation: Structural Determinants of Numb Association with the Cortical Membrane

UNC Libraries(2020)10.17615/vfjm-vw90

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0 citations

Sascha E. Dho, David P. Siderovski, Jo Ann Trejo, C. Jane McGlade

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

UNC Libraries(2021)10.17615/b9kr-6e14

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0 citations

Jason T. Snyder, Channing J. Der, John Sondek, Kent L. Rossman, Mark A. Baumeister +3 more

Receptor-selective Effects of Endogenous RGS3 and RGS5 to Regulate Mitogen-activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells

UNC Libraries(2021)10.17615/x6nw-pw95

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0DataRank · unranked

8 citations

David P. Siderovski, Richard R. Neubig, Min Liu, Bashar Mullah, Qin Wang

Contribution of HCN1 variant to sinus bradycardia: A case report

Journal of Arrhythmia(2021)10.1002/joa3.12598

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5 citations

Bryan Gall, Mackenzie Newman, Quincy A. Hathaway, Kathleen M. Brundage, Amanda G. Ammer +4 more

The stability of tastant detection by mouse lingual chemosensory tissue requires Regulator of G protein Signaling-21 (RGS21)

Chemical Senses(2021)10.1093/chemse/bjab048

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4 citations

Kayla Branyan, Joshua D. Gross, Paul D. Chantler, Adam J. Kimple, Aurélie Vandenbeuch +2 more

RGS12 and RGS14 GoLoco Motifs Are Gα i Interaction Sites with Guanine Nucleotide Dissociation Inhibitor Activity

UNC Libraries(2021)10.17615/n8h6-zn91

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David P. Siderovski, Hélène Tronchère, Marilyn G. Farquhar, Randall J. Kimple, Cynthia I. Behe +2 more

Minimal Determinants for Binding Activated Gα from the Structure of a Gα i1 −Peptide Dimer † , ‡

UNC Libraries(2021)10.17615/qech-wh86

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Екатерина С. Лобанова, Francis S. Willard, Zoey L. Fredericks, Alexander S. Shavkunov, Christopher O. Johnston +6 more

Mammalian Inscuteable Regulates Spindle Orientation and Cell Fate in the Developing Retina

UNC Libraries(2021)10.17615/cxkp-ks61

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David P. Siderovski, Mihaela Žigman, Nicole Firnberg, Alexander Schleiffer, Ben A. Barres +6 more

Gβ Association and Effector Interaction Selectivities of the Divergent Gγ Subunit Gγ 13

UNC Libraries(2021)10.17615/vjg3-b325

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Douglas A. Bayliss, Qiubo Lei, Rebecca A. Morris, Jennie R. Hillmann, Richard J. Miller +6 more

RGS12 Interacts with the SNARE-binding Region of the Ca v 2.2 Calcium Channel

UNC Libraries(2021)10.17615/sn9t-b714

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Marı́a A. Diversé-Pierluissi, Jesse Strock, King Kei Lau, David P. Siderovski, Nory Jun Cabanilla +2 more

Self-activating G protein α subunits engage seven-transmembrane regulator of G protein signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102167

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5 citations

William R. Jeck, David P. Siderovski, Dustin E. Bosch

The synthetic cannabinoid agonist WIN 55,212-2 reduces experimental pruritus via CB2 receptor activation

Neuropharmacology(2024)10.1016/j.neuropharm.2024.110216

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1 citations

David P. Siderovski, Steven G. Kinsey, A. Matthew Reck

Molecular Modeling and In Vitro Functional Analysis of the RGS12 PDZ Domain Variant Associated with High-Penetrance Familial Bipolar Disorder

International Journal of Molecular Sciences(2024)10.3390/ijms252111431

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0 citations

Joseph Mendez, Emily A. Oestreich, Dustin E. Bosch, David P. Siderovski, Percy S. Agogo-Mawuli