Stephen L. Hoffman

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 63 papers. Top paper: “Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity”.

Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity

Nature(2021)10.1038/s41586-021-03684-z

N/A

4.5DataRank · unranked

115 citations

Sara A. Healy, Jacquelyn Lane, David M. Cook, Sahand Kalhori, Charles W. Wyatt +31 more

Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial

Nature Medicine(2021)10.1038/s41591-021-01470-y

N/A

2.9DataRank · unranked

103 citations

Laura C. Steinhardt, Reuben Yego, Ryan E. Wiegand, Phillip A. Swanson, Natasha KC +25 more

Safety and efficacy of a three-dose regimen of Plasmodium falciparum sporozoite vaccine in adults during an intense malaria transmission season in Mali: a randomised, controlled phase 1 trial

The Lancet Infectious Diseases(2021)10.1016/s1473-3099(21)00332-7

N/A

1.7DataRank · unranked

79 citations

Sara A. Healy, Abdoulaye Katilé, Irfan Zaidi, Zonghui Hu, Bourama Kamaté +28 more

PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection

PLoS Pathogens(2021)10.1371/journal.ppat.1009594

N/A

1.5DataRank · unranked

60 citations

Gregory A. Deye, B. Kim Lee Sim, Shirley Galbiati, Jessie K. Kennedy, Kristen W. Cohen +9 more

Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial

Nature Communications(2021)10.1038/s41467-021-22740-w

N/A

1.3DataRank · unranked

57 citations

Rolf Fendel, Bianca Eder, Freia-Raphaella Lorenz, Natasha KC, Matthias Karnahl +22 more

A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection

npj Vaccines(2022)10.1038/s41541-022-00510-z

N/A

1.2DataRank · unranked

50 citations

Zita Sulyok, Mihály Sulyok, Zsofia Molnar, Albert Lalremruata, Carlos Lamsfus Calle +21 more

Safety and efficacy of PfSPZ Vaccine against malaria in healthy adults and women anticipating pregnancy in Mali: two randomised, double-blind, placebo-controlled, phase 1 and 2 trials

The Lancet Infectious Diseases(2024)10.1016/s1473-3099(24)00360-8

N/A

0.974DataRank · unranked

33 citations

Sara A. Healy, Agnes Mwakingwe-Omari, Djibrilla Issiaka, Aye Diallo, Seydou Traoré +51 more

PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial

EClinicalMedicine(2022)10.1016/j.eclinm.2022.101579

N/A

0.933DataRank · unranked

30 citations

Abdoulaye K. Koné, Karim Traoré, Amadou Niangaly, Bourèma Kouriba, Charles Arama +19 more

Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies

EMBO Molecular Medicine(2023)10.15252/emmm.202317454

N/A

0.618DataRank · unranked

18 citations

Giulia Costa, Clare Burn Aschner, Anna Obraztsova, Katherine Prieto, Caterina Canetta +8 more

Safety and protective efficacy of PfSPZ Vaccine administered to HIV-negative and -positive Tanzanian adults

Journal of Clinical Investigation(2024)10.1172/jci169060

N/A

0.482DataRank · unranked

17 citations

L. W. Preston Church, Florence A. Milando, Munira Qassim, Tobias Schindler, Mohammed Rashid +28 more

The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections

PLoS Pathogens(2023)10.1371/journal.ppat.1011468

N/A

0.424DataRank · unranked

11 citations

Ralf Krumkamp, Jana Held, Heidrun von Thien, Irene Wittmann, Yannick D. Höppner +19 more

Feasibility of direct venous inoculation of the radiation-attenuated Plasmodium falciparum whole sporozoite vaccine in children and infants in Siaya, western Kenya

Vaccine(2020)10.1016/j.vaccine.2020.05.008

N/A

0.409DataRank · unranked

12 citations

Y.R. Cherop, Tran Sang, Julie Gutman, Ryan E. Wiegand, Edward M. Nyang’au +16 more

Immune responses associated with protection induced by chemoattenuated PfSPZ vaccine in malaria-naive Europeans

JCI Insight(2024)10.1172/jci.insight.170210

N/A

0.214DataRank · unranked

3 citations

Simon P. Jochems, Vincent van Unen, Madeleine Eunice Betouke Ongwe, Wouter Aa de Steenhuijsen Piters, Koen A. Stam +9 more

Safety, tolerability, and protective efficacy of a radiation-attenuated, whole sporozoite malaria vaccine in children in Gabon: a randomised, double-blind, placebo-controlled, phase 2 trial

The Lancet Infectious Diseases(2025)10.1016/s1473-3099(25)00434-7

N/A

0.104DataRank · unranked

1 citations

Jeroen Bok, Ayodele Alabi, Anita L. Kabwende, Armel V. N. Mbouna, Juste Bie +13 more

Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity

Medical Microbiology and Immunology(2025)10.1007/s00430-025-00847-x

N/A

0.104DataRank · unranked

1 citations

Gloria P. Gómez-Pérez, Matthew N. McCall, Diana Barrios, Ruth Aguilar, Julia Fernández-Morata +12 more

Clonal evolution and specificity of the human T follicular helper cell response to Plasmodium falciparum circumsporozoite protein

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.10.459751

N/A

0DataRank · unranked

1 citations

Anna Obraztsova, Julia Puchan, Rebecca Hundsdorfer, Sumana Chakravarty, B. Kim Lee Sim +5 more

Progress in Development of an Automated Mosquito Salivary Gland Extractor: A Step Forward to Malaria Vaccine Mass Production

(2021)10.1109/case49439.2021.9551500

N/A

0DataRank · unranked

1 citations

Zhuoqun Zhang, Zhuohong He, Parth Vora, Alan Lai, Balázs Vágvölgyi +8 more

Genome, proteome, and immunome data explain why 6 month controlled human malaria infection with sporozoites of the Pf7G8 clone of Plasmodium falciparum is a rigorous predictor of the efficacy of the PfNF54-based PfSPZ Vaccine in Africa

medRxiv(2021)10.1101/2021.12.09.21266528

N/A

0DataRank · unranked

0 citations

Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy +9 more

Role of human Pegivirus infections in whole Plasmodium falciparum sporozoite vaccination and controlled human malaria infection in African volunteers

Research Square(2021)10.21203/rs.3.rs-64109/v2

N/A

0DataRank · unranked

0 citations

Tobias Schindler, Jean‐Pierre Dangy, Nina Orlova-Fink, Jose Raso Bieri, Maxmillian Mpina +19 more

A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria

Science Translational Medicine(2022)10.1126/scitranslmed.abj3776

N/A

0DataRank · unranked

53 citations

Alphonse Ouédraogo, Alfred B. Tiono, Jean Moïse Tanga Kaboré, Edith C. Bougouma, Maurice Ouattara +23 more

Cryopreserved Sporozoites with and without the Glycolipid Adjuvant 7DW8-5 Protect in Prime-and-Trap Malaria Vaccination

American Journal of Tropical Medicine and Hygiene(2022)10.4269/ajtmh.21-1084

N/A

0DataRank · unranked

17 citations

Melanie J. Shears, Jokichi Matsubara, Anya C. Kalata, Annette M. Seilie, Irene Cruz Talavera +7 more

Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites

Malaria Journal(2022)10.1186/s12936-022-04261-z

N/A

0DataRank · unranked

13 citations

Melanie J. Shears, Eric R. James, Urvashi Rai, Natasha KC, Solomon Conteh +5 more

Cryopreservation of Anopheles stephensi embryos

Scientific Reports(2022)10.1038/s41598-021-04113-x

N/A

0DataRank · unranked

12 citations

Yingda Wen, James Overby, Kristen M. Pluchino, Shane McTighe, S.L. Jr. Matheny +4 more

A First for Human Vaccinology: GMP Compliant Radiation Attenuation of Plasmodium falciparum Sporozoites for Production of a Vaccine Against Malaria

Frontiers in Immunology(2022)10.3389/fimmu.2022.851028

N/A

0DataRank · unranked

7 citations

Steve Matheny, James Overby, B. Kim Lee Sim, Abraham G. Eappen, Tao Li +8 more

Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa

Nature Communications(2022)10.1038/s41467-022-30882-8

N/A

0DataRank · unranked

12 citations

Ankit Dwivedi, Kara A. Moser, Mahamadou S. Sissoko, Judith E. Epstein, Sara A. Healy +9 more

Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

npj Vaccines(2022)10.1038/s41541-022-00473-1

N/A

0DataRank · unranked

7 citations

Rolf Fendel, Freia-Raphaella Lorenz, Patricia Granados Bayon, Sina Brückner, Meral Esen +9 more

Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice

Biomolecules(2022)10.3390/biom13010008

N/A

0DataRank · unranked

2 citations

Caroline J. Duncombe, Anya C. Kalata, Ethan Conrad, Sumana Chakravarty, B. Kim Lee Sim +5 more

Immunological profiles associated with distinct parasitemic states in volunteers undergoing malaria challenge in Gabon

Scientific Reports(2022)10.1038/s41598-022-17725-8

N/A

0DataRank · unranked

3 citations

Sanne E. de Jong, Yvonne C. M. Kruize, Yoanne D. Mouwenda, Madeleine Eunice Betouke Ongwe, Yabo Josiane Honkpéhèdji +11 more

The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections

medRxiv(2022)10.1101/2022.12.05.22283093

N/A

0DataRank · unranked

0 citations

Ralf Krumkamp, Jana Held, Heidrun von Thien, Irene Wittmann, Yannick D. Höppner +18 more

Sporozoite immunization: innovative translational science to support the fight against malaria

Expert Review of Vaccines(2023)10.1080/14760584.2023.2245890

N/A

0DataRank · unranked

47 citations

L. W. Preston Church, Tooba Murshedkar, Peter F. Billingsley, Eric R. James, Mei‐Chun Chen +41 more

Preliminary studies on the immunogenicity of a prime-and-trap malaria vaccine in nonhuman primates

Vaccine(2023)10.1016/j.vaccine.2023.07.067

N/A

0DataRank · unranked

2 citations

Felicia Watson, Brad Stone, Irene Cruz Talavera, Chaitra Parthiban, Jokichi Matsubara +5 more

Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research

Malaria Journal(2023)10.1186/s12936-023-04788-9

N/A

0DataRank · unranked

2 citations

Rebekah A. Reynolds, Caroline J. Duncombe, Felicia Watson, Weston J. Staubus, Chris Chavtur +6 more

Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Research Square(2023)10.21203/rs.3.rs-3243319/v1

N/A

0DataRank · unranked

1 citations

Melanie J. Shears, Anya C. Kalata, Caroline J. Duncombe, Annette M. Seilie, Chris Chavtur +10 more

Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.19.524692

N/A

0DataRank · unranked

0 citations

Giulia Costa, Clare Burn Aschner, Anna Obraztsova, Katherine Prieto, Caterina Canetta +8 more

Plasmodium knowlesi in pig-tailed macaques: a new model for malaria vaccine research

Research Square(2023)10.21203/rs.3.rs-3283109/v1

N/A

0DataRank · unranked

0 citations

Rebekah A. Reynolds, Caroline J. Duncombe, Felicia Watson, Weston J. Staubus, Chris Chavtur +6 more

A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion

EMBO Molecular Medicine(2024)10.1038/s44321-024-00057-7

N/A

0DataRank · unranked

29 citations

Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil +7 more

Machine learning prediction of malaria vaccine efficacy based on antibody profiles

PLoS Computational Biology(2024)10.1371/journal.pcbi.1012131

N/A

0DataRank · unranked

9 citations

Bernhard Reuter, Rolf Fendel, Stephen L. Hoffman, Joseph J. Campo, Philip L. Felgner +4 more

Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine

JCI Insight(2024)10.1172/jci.insight.167408

N/A

0DataRank · unranked

9 citations

Jyoti Bhardwaj, Morgan R. Little, Prasida Holla, Aditi Upadhye, Elizabeth M. Fusco +29 more

Piloting delivery of PfSPZ vaccines for malaria through a cryogenic vaccine cold chain to travel and military medicine clinics

Journal of Travel Medicine(2024)10.1093/jtm/taae007

N/A

0DataRank · unranked

3 citations

L. W. Preston Church, Stephen L. Hoffman, Thomas L. Richie, Brian D. Robertson, Patrick W. Hickey +14 more

Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Scientific Reports(2024)10.1038/s41598-024-53118-9

N/A

0DataRank · unranked

3 citations

Melanie J. Shears, Anya C. Kalata, Caroline J. Duncombe, Annette M. Seilie, Chris Chavtur +10 more

PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adults

EBioMedicine(2024)10.1016/j.ebiom.2024.105364

N/A

0DataRank · unranked

3 citations

Freia-Raphaella Lorenz, Annie Yang, Stephanie Sefried, Tobias Schindler, Maximilian Mpina +20 more

Efficacy of ProC6C-AlOH/Matrix-M against Plasmodium falciparum infection and mosquito transmission: a phase 2, randomised, controlled human malaria infection study

The Lancet Infectious Diseases(2025)10.1016/s1473-3099(25)00664-4

N/A

0DataRank · unranked

2 citations

Jordan Plieskatt, Moussa Thienta, Bourama Kamaté, Ebenezer Addo Ofori, Markus Gmeiner +29 more

Complete attenuation of Plasmodium falciparum sporozoites by atovaquone–proguanil

EMBO Molecular Medicine(2025)10.1038/s44321-025-00301-8

N/A

0DataRank · unranked

2 citations

Zita Sulyok, Katja Müller, Rolf Fendel, Mihály Sulyok, Johannes Friesen +35 more

Protective targets of PfSPZ vaccines identified from whole-genome sieve analysis of isolates from malaria vaccine efficacy trials in West Africa

medRxiv(2025)10.1101/2025.03.04.25323352

N/A

0DataRank · unranked

1 citations

Ryan J. Scalsky, David G. Harris, Thomas C. Stabler, Biraj Shrestha, Sudhaunshu Joshi +18 more

Successful insertion and expression of a tetracycline transactivator in Anopheles stephensi associated with increased egg production and decreased hatching rate

Research Square(2025)10.21203/rs.3.rs-6270709/v1

N/A

0DataRank · unranked

0 citations

Ishaan Samantray, Robert Alford, Robert A. Harrell, Grace Jennings, Tales Vicari Pascini +5 more

Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity

Research Square(2025)10.21203/rs.3.rs-6221433/v1

N/A

0DataRank · unranked

0 citations

Gloria P. Gómez-Pérez, Matthew N. McCall, Diana Barrios, Ruth Aguilar, Julia Fernández-Morata +12 more

Controlled human malaria infection with NF54 and 7G8 strains elicit differential antibody responses to Plasmodium falciparum peptides

Frontiers in Immunology(2025)10.3389/fimmu.2025.1641280

N/A

0DataRank · unranked

0 citations

Travis L. Jensen, Kirsten E. Lyke, Matthew B. Laurens, Joana C. Silva, Emily M. Stucke +15 more

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential

Genome Medicine(2020)10.1186/s13073-019-0708-9

N/A

0DataRank · unranked

88 citations

Elliott F. Drábek, Ankit Dwivedi, Emily M. Stucke, Jonathan Crabtree, Antoine Dara +29 more

Successful insertion and expression of a tetracycline transactivator in Anopheles stephensi associated with increased egg production and decreased hatching rate

Parasites & Vectors(2025)10.1186/s13071-025-07003-7

N/A

0DataRank · unranked

0 citations

Ishaan Samantray, Robert Alford, Robert A. Harrell, Grace Jennings, Tales Vicari Pascini +6 more

Caregiver and community perceptions and experiences participating in an infant malaria prevention trial of PfSPZ Vaccine administered by direct venous inoculation: a qualitative study in Siaya County, western Kenya

Malaria Journal(2020)10.1186/s12936-020-03293-7

N/A

0DataRank · unranked

21 citations

Joseph G. Rosen, Reuben Yego Cherop, Simon Kariuki, Stephen L. Hoffman, Robert A. Seder +3 more

Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults

Vaccine(2020)10.1016/j.vaccine.2020.04.046

N/A

0DataRank · unranked

16 citations

Ulysse Ateba Ngoa, Javier Ibáñez, Jean Claude Dejon‐Agobé, Benjamin Mordmüller, Jean Ronald Edoa +15 more

Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models

Malaria Journal(2020)10.1186/s12936-020-03385-4

N/A

0DataRank · unranked

13 citations

Annette M. Seilie, B. Kim Lee Sim, Stephen L. Hoffman, Sean C. Murphy, Melanie J. Shears

Recombinase Polymerase Amplification and Lateral Flow Assay for Ultrasensitive Detection of Low-Density Plasmodium falciparum Infection from Controlled Human Malaria Infection Studies and Naturally Acquired Infections

Journal of Clinical Microbiology(2020)10.1128/jcm.01879-19

N/A

0DataRank · unranked

40 citations

Nguyen Trong The, Matthew B. B. McCall, Ghyslain Mombo‐Ngoma, Sélidji Todagbé Agnandji, Ayôla Akim Adégnika +6 more

Mapping of safe and early chemo-attenuated live Plasmodium falciparum immunization identifies immune signature of vaccine efficacy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.14.296152

N/A

0DataRank · unranked

6 citations

Zita Sulyok, Katja Müller, Rolf Fendel, Carlos Lamsfus Calle, Mihály Sulyok +35 more

Lipoic acid biosynthesis is essential for Plasmodium falciparum transmission and influences redox response and carbon metabolism of parasite asexual blood stages

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.17.099630

N/A

0DataRank · unranked

1 citations

T. R. Santha Kumar, Philipp P. Henrich, Larissa Laine, Gavin Blackburn, Achuthanunni Chokkathukalam +10 more

Role of Human Pegivirus Infections in Whole P. falciparum Sporozoite Vaccination and Controlled Human Malaria Infection in African Volunteers

Research Square(2020)10.21203/rs.3.rs-64109/v1

N/A

0DataRank · unranked

0 citations

Tobias Schindler, Jean‐Pierre Dangy, Nina Orlova-Fink, Jose Raso Bieri, Maxmillian Mpina +19 more

Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

PLoS neglected tropical diseases(2021)10.1371/journal.pntd.0009361

N/A

0DataRank · unranked

24 citations

Juliana Boex Mengue, Jean Claude Dejon‐Agobé, Rolf Fendel, Javier Ibáñez, Ulysse Ateba Ngoa +20 more

Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes

International Journal for Parasitology(2021)10.1016/j.ijpara.2020.10.011

N/A

0DataRank · unranked

18 citations

T. R. Santha Kumar, Philipp P. Henrich, Larissa Laine, Gavin Blackburn, Achuthanunni Chokkathukalam +11 more

Expansion of Functional Myeloid-Derived Suppressor Cells in Controlled Human Malaria Infection

Frontiers in Immunology(2021)10.3389/fimmu.2021.625712

N/A

0DataRank · unranked

19 citations

Rolf Fendel, Anurag Singh, Thomas L. Richie, Stephen L. Hoffman, Peter G. Kremsner +2 more

Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence

PLoS Pathogens(2021)10.1371/journal.ppat.1009770

N/A

0DataRank · unranked

18 citations

Abraham G. Eappen, Robert Alford, William Reid, Robert A. Harrell, Maryam Hosseini +6 more

Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections

Malaria Journal(2021)10.1186/s12936-021-03818-8

N/A

0DataRank · unranked

11 citations

Kasim I. George, Abraham G. Eappen, Robert A. Harrell, Robert Alford, Tao Li +5 more

Role of human Pegivirus infections in whole Plasmodium falciparum sporozoite vaccination and controlled human malaria infection in African volunteers

Virology Journal(2021)10.1186/s12985-021-01500-8

N/A

0DataRank · unranked

4 citations

Tobias Schindler, Jean‐Pierre Dangy, Nina Orlova-Fink, Jose Raso Bieri, Maxmillian Mpina +19 more

Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine

medRxiv(2021)10.1101/2021.10.08.21264577

N/A

0DataRank · unranked

2 citations

Jyoti Bhardwaj, Morgan R. Little, Prasida Holla, Aditi Upadhye, Phillip A. Swanson +25 more