🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Wenjie Wu

Roswell Park Comprehensive Cancer Center

ORCID: 0000-0002-0907-0561

Also affiliated with Canget BioTekpharma (United States)

Immunology and MicrobiologyEnvironmental ScienceNeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 5 papers. Top paper: “Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer”.

Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer

Journal of Pharmaceutical Analysis(2024)10.1016/j.jpha.2024.101001

N/A

0.312DataRank · unranked

7 citations

Wenjie Wu, Li Yan, Leslie Curtin, Melanie M. Farrauto, Sandra Sexton +6 more

Sensitivity of colorectal or pancreatic cancers with high DDX5 and mutations in Kras and p53 genes to FL118 treatment.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.e16102

N/A

0DataRank · unranked

2 citations

Wenjie Wu, Jianqun Liao, Sreevidya Santha, Leman Aljahdali, Jue Wang +5 more

FL118, acting as a ‘molecular glue degrader’, binds to, dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy

Clinical and Translational Medicine(2022)10.1002/ctm2.881

N/A

0DataRank · unranked

40 citations

Wenjie Wu, Ieman Aljahdali, Jianqun Liao, Sreevidya Santha, Christos Fountzilas +3 more

Structure–Activity Relationship of FL118 Platform Position 7 Versus Position 9-Derived Compounds and Their Mechanism of Action and Antitumor Activity

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01589

N/A

0DataRank · unranked

8 citations

Xiang Ling, Ruojiong Wang, Haonan Xiong, Liuzhi Hu, Zhikun Yang +8 more

FL496, an FL118-derived small molecule, induces growth inhibition, senescence, and apoptosis of malignant pleural mesothelioma (MPM) cells, and exhibits anti-MPM tumor efficacy strikingly superior to the pemetrexed-cisplatin combination

Journal of Experimental & Clinical Cancer Research(2025)10.1186/s13046-025-03547-9

N/A

0DataRank · unranked

2 citations

Xiang Ling, Wenjie Wu, Wenchao Wang, Dan Li, Renyuan Zhang +6 more