Henry R. Kranzler

Also affiliated with University of Pennsylvania

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

8.0Author DataRank

Indexed papers

11in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 11 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program

Science(2024)10.1126/science.adj1182

Top 7%

3.2DataRank

Top 7%377 citations

Jennifer E. Huffman, Alex A Rodriguez, Mitchell Conery, Molei Liu, Yuk‐Lam Ho +66 more

Papers

Driven by 110 papers — median percentile 50. Top paper: “Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits”.

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits

Nature Neuroscience(2020)10.1038/s41593-020-0643-5

N/A

6.1DataRank · unranked

406 citations

Julia Sealock, Sandra Sanchez-Roige, Toni-Kim Clarke, Daniel F. Levey, Zhongshan Cheng +21 more

A large-scale genome-wide association study meta-analysis of cannabis use disorder

The Lancet Psychiatry(2020)10.1016/s2215-0366(20)30339-4

N/A

5.5DataRank · unranked

384 citations

Ditte Demontis, Thorgeir E. Thorgeirsson, Raymond K. Walters, Renato Polimanti, Alexander S. Hatoum +91 more

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses

Alcoholism: Clinical and Experimental Research(2015)10.1111/acer.12792

N/A

3.9DataRank · unranked

127 citations

Henry R. Kranzler, Amy B. Hart

Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program

Science(2024)10.1126/science.adj1182

Top 7%

3.2DataRank

Top 7%377 citations

Jennifer E. Huffman, Alex A Rodriguez, Mitchell Conery, Molei Liu, Yuk‐Lam Ho +66 more

Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals

Nature Communications(2020)10.1038/s41467-020-18489-3

N/A

2.6DataRank · unranked

123 citations

Boyang Li, Kathleen A. McGinnis, Rachel Vickers‐Smith, Cecilia Dao, Ning Sun +9 more

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals

Nature Medicine(2023)10.1038/s41591-023-02653-5

Top 10%

2.1DataRank

Top 10%181 citations

Rachel L. Kember, Joseph D. Deak, Heng Xu, Sylvanus Toikumo, Kai Yuan +44 more

Genome-wide meta-analysis of alcohol use disorder in East Asians

Neuropsychopharmacology(2022)10.1038/s41386-022-01265-w

Top 18%

1.1DataRank

Top 18%38 citations

Rasmon Kalayasiri, Yan Sun, Yaira Z. Nuñez, Hong‐Wen Deng, Xiang‐Ding Chen +10 more

A multi-ancestry genetic study of pain intensity in 598,339 veterans

Nature Medicine(2024)10.1038/s41591-024-02839-5

N/A

0.904DataRank · unranked

44 citations

Rachel Vickers‐Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E. Hartwell +15 more

Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes

Nature Human Behaviour(2024)10.1038/s41562-024-01851-6

N/A

0.770DataRank · unranked

56 citations

Mariela Jennings, Benjamin K. Pham, Hyunjoon Lee, Travis T. Mallard, Sevim B. Bianchi +32 more

A Delta-Opioid Receptor Gene Polymorphism Moderates the Therapeutic Response to Extended-Release Buprenorphine in Opioid Use Disorder

The International Journal of Neuropsychopharmacology(2020)10.1093/ijnp/pyaa069

N/A

0.554DataRank · unranked

14 citations

Kevin G. Lynch, Richard C. Crist, Emily E. Hartwell, Anne Le Moigne, Céline M. Laffont +2 more

A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens

Scientific Reports(2024)10.1038/s41598-024-69255-0

Top 43%

0.429DataRank

Top 43%11 citations

Samar Nasser Chehimi, R. Merkel, Sylvanus Toikumo, Wade H. Berrettini, Henry R. Kranzler +5 more

Genome-wide Meta-analysis of Alcohol Use Disorder in East Asians

medRxiv(2021)10.1101/2021.09.17.21263732

Top 47%

0.382DataRank

Top 47%5 citations

Rasmon Kalayasiri, Yan Sun, Yaira Z. Nuñez, Hong‐Wen Deng, Xiang‐Ding Chen +10 more

Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders

Molecular Psychiatry(2024)10.1038/s41380-024-02446-3

N/A

0.373DataRank · unranked

11 citations

Eleni Friligkou, Brendan Stiltner, Gita A. Pathak, Solveig Løkhammer, Daniel F. Levey +11 more

Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits

Neuropsychopharmacology(2024)10.1038/s41386-024-01922-2

Top 52%

0.329DataRank

Top 52%7 citations

Zeal Jinwala, Jackson Milone, Sarah Stewart de Ramirez, Joel Gelernter, Henry R. Kranzler +2 more

Investigating the Contribution of Coding Variants in Alcohol Use Disorder Using Whole-Exome Sequencing Across Ancestries

Biological Psychiatry(2025)10.1016/j.biopsych.2025.01.020

Top 54%

0.305DataRank

Top 54%6 citations

Henry R. Kranzler, Joel Gelernter, Hang Zhou, Lu Wang

Polygenic risk score for type 2 diabetes shows context-dependent effects across populations

Nature Communications(2025)10.1038/s41467-025-63546-4

N/A

0.165DataRank · unranked

2 citations

Yanwei Cai, Daeeun Kim, Roelof A. J. Smit, Zhe Wang, Kruthika R. Iyer +169 more

Multi-ancestry Whole-exome Sequencing Study of Alcohol Use Disorder in Two Cohorts

medRxiv(2024)10.1101/2024.04.05.24305412

Top 70%

0.165DataRank

Top 70%2 citations

Henry R. Kranzler, Joel Gelernter, Hang Zhou, Lu Wang

A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

medRxiv(2021)10.1101/2020.12.26.20248491

N/A

0DataRank · unranked

16 citations

Shweta Ramdas, Kimberly Lorenz, Xiuqing Guo, Rebecca Darlay, Heather J. Cordell +85 more

Multi-trait genome-wide association study of opioid addiction: OPRM1 and Beyond

medRxiv(2021)10.1101/2021.09.13.21263503

N/A

0DataRank · unranked

9 citations

Ravi Mathur, Jesse A. Marks, Linran Zhou, Bryan C. Quach, Alex Waldrop +37 more

Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry

medRxiv(2021)10.1101/2021.12.04.21267094

N/A

0DataRank · unranked

4 citations

Hang Zhou, Marco Galimberti, Daniel F. Levey, Frank R. Wendt, Sandra Sanchez-Roige +15 more

Racial Inequalities in Alcohol Use Disorder Diagnosis in a Sample of 700,000 Veterans

medRxiv(2021)10.1101/2021.07.14.21256113

N/A

0DataRank · unranked

3 citations

Amy C. Justice, William C. Becker, Christopher T. Rentsch, Brenda Curtis, Anita Fernander +6 more

Comorbid-phenome prediction and phenotype risk scores enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder

medRxiv(2021)10.1101/2021.07.13.21260369

N/A

0DataRank · unranked

0 citations

Gita A. Pathak, Joseph D. Deak, Flavio De Angelis, Dóra Koller, Brenda Cabrera‐Mendoza +9 more

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Nature Genetics(2022)10.1038/s41588-022-01078-z

N/A

0DataRank · unranked

195 citations

Shweta Ramdas, Kimberly Lorenz, Xiuqing Guo, Rebecca Darlay, Heather J. Cordell +86 more

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

Molecular Psychiatry(2022)10.1038/s41380-022-01709-1

N/A

0DataRank · unranked

138 citations

Hang Zhou, Marco Galimberti, Daniel F. Levey, Frank R. Wendt, Sandra Sanchez-Roige +15 more

Phenome-wide Association Analysis of Substance Use Disorders in a Deeply Phenotyped Sample

Biological Psychiatry(2022)10.1016/j.biopsych.2022.08.010

N/A

0DataRank · unranked

51 citations

Emily E. Hartwell, Heng Xu, James A. Rotenberg, Laura Almasy, Hang Zhou +3 more

Genome-Wide Investigation of Maximum Habitual Alcohol Intake in US Veterans in Relation to Alcohol Consumption Traits and Alcohol Use Disorder

JAMA Network Open(2022)10.1001/jamanetworkopen.2022.38880

N/A

0DataRank · unranked

44 citations

Daniel Levey, Frank R. Wendt, Hang Zhou, Marco Galimberti, Henry R. Kranzler +53 more

ODACH: a one-shot distributed algorithm for Cox model with heterogeneous multi-center data

Scientific Reports(2022)10.1038/s41598-022-09069-0

N/A

0DataRank · unranked

35 citations

Rui Duan, Adam C. Naj, Henry R. Kranzler, Jiang Bian, Yong Chen +1 more

The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study

Biological Psychiatry(2022)10.1016/j.biopsych.2022.08.012

N/A

0DataRank · unranked

34 citations

Miguel Garcia‐Argibay, Brenda Cabrera‐Mendoza, Unnur Valdimarsdóttir, Joel Gelernter, Murray B Stein +91 more

Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits

Neuropsychopharmacology(2022)10.1038/s41386-022-01406-1

N/A

0DataRank · unranked

18 citations

Heng Xu, Joel Gelernter, Rachel L. Kember, Henry R. Kranzler, Sylvanus Toikumo

Multisite learning of high-dimensional heterogeneous data with applications to opioid use disorder study of 15,000 patients across 5 clinical sites

Scientific Reports(2022)10.1038/s41598-022-14029-9

N/A

0DataRank · unranked

8 citations

Rui Duan, Chongliang Luo, Alexis Ogdie, Jason H. Moore, Henry R. Kranzler +3 more

Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function

Neuropsychopharmacology(2022)10.1038/s41386-022-01325-1

N/A

0DataRank · unranked

4 citations

Andrey A. Shabalin, Rachel L. Kember, Anna R. Docherty, Hang Zhou, Vincent Koppelmans +7 more

Novel digital approaches to the assessment of problematic opioid use

BioData Mining(2022)10.1186/s13040-022-00301-1

N/A

0DataRank · unranked

2 citations

Henry R. Kranzler, Jason H. Moore, Philip J. Freda

Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factors

medRxiv(2022)10.1101/2022.07.03.22277199

N/A

0DataRank · unranked

9 citations

Niamh Mullins, Allison E. Ashley‐Koch, Xuejun Qin, Jonathan R. I. Coleman, Andrey A. Shabalin +95 more

Phenome-wide association analysis of substance use disorders in a deeply phenotyped sample

medRxiv(2022)10.1101/2022.02.09.22270737

N/A

0DataRank · unranked

8 citations

Emily E. Hartwell, Heng Xu, James A. Rotenberg, Laura Almasy, Hang Zhou +3 more

Genome-wide investigation of maximum habitual alcohol intake (MaxAlc) in 247,755 European and African Ancestry U.S. Veterans informs the relationship between habitual alcohol consumption and alcohol use disorder

medRxiv(2022)10.1101/2022.05.02.22274580

N/A

0DataRank · unranked

5 citations

Daniel F. Levey, Frank R. Wendt, Hang Zhou, Marco Galimberti, Henry R. Kranzler +6 more

Integrating Human Brain Proteomic Data with Genome-Wide Association Study Findings Identifies Novel Brain Proteins in Substance Use Traits

medRxiv(2022)10.1101/2022.02.02.22270270

N/A

0DataRank · unranked

2 citations

Heng Xu, Rachel L. Kember, Henry R. Kranzler, Sylvanus Toikumo

Using 18 F-NOS PET Imaging to Measure Pulmonary Inflammation in Electronic and Combustible Cigarette Users: A Pilot Study

medRxiv(2022)10.1101/2022.06.15.22276438

N/A

0DataRank · unranked

1 citations

Robert K. Doot, Anthony J. Young, Hsiaoju Lee, Erin K. Schubert, Corinde E. Wiers +5 more

Polygenic Risk for Substance-Related Traits Predicts Substance Use Onset and Progression: Sex and Population Group Differences

medRxiv(2022)10.1101/2022.09.29.22280477

N/A

0DataRank · unranked

0 citations

Richard Feinn, Heng Xu, Brendan L. Ho, Divya Saini, Olivia R. Nicastro +6 more

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors

American Journal of Psychiatry(2023)10.1176/appi.ajp.21121266

N/A

0DataRank · unranked

150 citations

Niamh Mullins, Allison E. Ashley‐Koch, Xuejun Qin, Jonathan R. I. Coleman, Andrey A. Shabalin +95 more

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications

Nature Genetics(2023)10.1038/s41588-023-01563-z

N/A

0DataRank · unranked

119 citations

Marco Galimberti, Joseph D. Deak, Frank R. Wendt, Arjun Bhattacharya, Dóra Koller +26 more

Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans

American Journal of Psychiatry(2023)10.1176/appi.ajp.21111097

N/A

0DataRank · unranked

37 citations

Amy C. Justice, William C. Becker, Christopher T. Rentsch, Brenda Curtis, Anita Fernander +6 more

Metabolic Profiles Associated with Opioid Use and Opioid Use Disorder: a Narrative Review of the Literature

Current Addiction Reports(2023)10.1007/s40429-023-00493-4

N/A

0DataRank · unranked

18 citations

Xinyi Li, Sianneh A. Vesslee, Henry R. Kranzler, Zhenhao Shi, Corinde E. Wiers +1 more

Hippocampal volume loss in individuals with a history of non‐fatal opioid overdose

Addiction Biology(2023)10.1111/adb.13336

N/A

0DataRank · unranked

13 citations

Xinyi Li, Laís S. Pereira‐Rufino, Peter Manza, Ilya M. Nasrallah, Sandhitsu R. Das +7 more

Molecular Imaging of Pulmonary Inflammation in Users of Electronic and Combustible Cigarettes: A Pilot Study

Journal of Nuclear Medicine(2023)10.2967/jnumed.122.264529

N/A

0DataRank · unranked

22 citations

Robert K. Doot, Anthony J. Young, Hsiaoju Lee, Erin K. Schubert, Corinde E. Wiers +5 more

Polysubstance addiction patterns among 7,989 individuals with cocaine use disorder

iScience(2023)10.1016/j.isci.2023.107336

N/A

0DataRank · unranked

14 citations

Robert H. Pietrzak, Daniel S. Tylee, Yaira Z. Nuñez, Keyrun Adhikari, Henry R. Kranzler +3 more

Does polygenic risk for substance‐related traits predict ages of onset and progression of symptoms?

Addiction(2023)10.1111/add.16210

N/A

0DataRank · unranked

13 citations

Richard Feinn, Heng Xu, Brendan L. Ho, Divya Saini, Olivia R. Nicastro +6 more

Peripheral and Central Iron Measures in Alcohol Use Disorder and Aging: A Quantitative Susceptibility Mapping Pilot Study

International Journal of Molecular Sciences(2023)10.3390/ijms24054461

N/A

0DataRank · unranked

5 citations

Xinyi Li, Juliana I. Byanyima, Sianneh A. Vesslee, Thanh D. Nguyen, Yi Wang +7 more

Genome-Wide Association Study of Chronic Dizziness in the Elderly Identifies Loci Implicating MLLT10, BPTF, LINC01224, and ROS1

Journal of the Association for Research in Otolaryngology(2023)10.1007/s10162-023-00917-y

N/A

0DataRank · unranked

5 citations

Daniel Munro, Daniel Dochtermann, Poornima Devineni, Saiju Pyarajan, Million Veteran Program +91 more

Genome-wide association study of antisocial personality disorder diagnostic criteria provides evidence for shared risk factors across disorders

Psychiatric Genetics(2023)10.1097/ypg.0000000000000352

N/A

0DataRank · unranked

6 citations

Hang Zhou, Johan H. Thygesen, Mathis Heydtmann, Iain Smith, Franziska Degenhardt +7 more

Machine Learning of Functional Connectivity to Biotype Alcohol and Nicotine Use Disorders

Biological Psychiatry Cognitive Neuroscience and Neuroimaging(2023)10.1016/j.bpsc.2023.08.010

N/A

0DataRank · unranked

5 citations

Wuyi Wang, Yu Chen, Henry R. Kranzler, Chiang‐Shan R. Li, Jinbo Bi +1 more

Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes

medRxiv(2023)10.1101/2023.03.27.23287713

N/A

0DataRank · unranked

7 citations

Mariela Jennings, Benjamin K. Pham, Hyunjoon Lee, Travis T. Mallard, Sevim B. Bianchi +31 more

The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans

medRxiv(2023)10.1101/2023.03.09.23286958

N/A

0DataRank · unranked

4 citations

Rachel Vickers‐Smith, Zeal Jinwala, Heng Xu, Divya Saini, Emily E. Hartwell +15 more

The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans

Research Square(2023)10.21203/rs.3.rs-2670887/v1

N/A

0DataRank · unranked

3 citations

Sylvanus Toikumo, Rachel Vickers‐Smith, Zeal Jinwala, Heng Xu, Divya Saini +14 more

Pharmacokinetic effects of a single-dose nutritional ketone ester supplement on brain glucose and ketone metabolism in alcohol use disorder

medRxiv(2023)10.1101/2023.09.25.23296090

N/A

0DataRank · unranked

2 citations

Anthony J. Young, Zhenhao Shi, Juliana I. Byanyima, Sianneh Vesslee, Rishika Reddy +10 more

Association Patterns of Antisocial Personality Disorder across Substance Use Disorders

medRxiv(2023)10.1101/2023.09.15.23295625

N/A

0DataRank · unranked

1 citations

Brendan Stiltner, Yaira Z. Nuñez, Keyrun Adhikari, Joseph D. Deak, Robert H. Pietrzak +4 more

Ketone supplementation dampens subjective and objective responses to alcohol in rats and humans

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.23.558269

N/A

0DataRank · unranked

1 citations

Zhenhao Shi, Dustin R. Todaro, Timothy Pond, Juliana I. Byanyima, Sianneh Vesslee +9 more

Polysubstance addiction and psychiatric, somatic comorbidities among 7,989 individuals with cocaine use disorder: a latent class analysis

medRxiv(2023)10.1101/2023.02.08.23285653

N/A

0DataRank · unranked

0 citations

Robert H. Pietrzak, Daniel S. Tylee, Yaira Z. Nuñez, Keyrun Adhikari, Henry R. Kranzler +3 more

A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology

Nature Human Behaviour(2024)10.1038/s41562-024-01951-3

N/A

0DataRank · unranked

62 citations

Marco Galimberti, Yue Liu, S L Beck, Aliza P. Wingo, Thomas S. Wingo +7 more

Genetic and non-genetic predictors of risk for opioid dependence

Psychological Medicine(2024)10.1017/s0033291723003732

N/A

0DataRank · unranked

18 citations

Joseph D. Deak, Henry R. Kranzler, Robert H. Pietrzak, Joel Gelernter, Peter J. Na

Genetically predicted lipoprotein(a) associates with coronary artery plaque severity independent of low-density lipoprotein cholesterol

European Journal of Preventive Cardiology(2024)10.1093/eurjpc/zwae271

N/A

0DataRank · unranked

16 citations

Rose D. L. Huang, Austin T. Hilliard, Michael G. Levin, Disha Sharma, Blake Thomson +89 more

Association patterns of antisocial personality disorder across substance use disorders

Translational Psychiatry(2024)10.1038/s41398-024-03054-z

N/A

0DataRank · unranked

8 citations

Brendan Stiltner, Yaira Z. Nuñez, Keyrun Adhikari, Joseph D. Deak, Robert H. Pietrzak +4 more

Reductions in World Health Organization Risk Drinking Level Are Associated With Reductions in Alcohol Use Disorder Diagnosis and Criteria: Evidence From an Alcohol Pharmacotherapy Trial

Journal of Addiction Medicine(2024)10.1097/adm.0000000000001303

N/A

0DataRank · unranked

6 citations

Felicia R. Tuchman, Kevin A. Hallgren, Henry R. Kranzler, Henri‐Jean Aubin, Stephanie S. O’Malley +5 more

Multiomic Network Analysis Identifies Dysregulated Neurobiological Pathways in Opioid Addiction

Biological Psychiatry(2024)10.1016/j.biopsych.2024.11.013

N/A

0DataRank · unranked

5 citations

David Kainer, Matthew Lane, Mikaela Cashman, J Izaak Miller, Michael R. Garvin +22 more

Reductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder

Alcohol and Alcoholism(2024)10.1093/alcalc/agae022

N/A

0DataRank · unranked

4 citations

Dylan K. Richards, Felicia R. Tuchman, Kevin A. Hallgren, Henry R. Kranzler, Henri‐Jean Aubin +7 more

Subjective cognitive concerns, APOE ε4, PTSD symptoms, and risk for dementia among older veterans

Alzheimer s Research & Therapy(2024)10.1186/s13195-024-01512-w

N/A

0DataRank · unranked

6 citations

Jennifer R. Fonda, Mark W. Miller, Erika J. Wolf, Rui Zhang, Richard Sherva +90 more

Ketone Supplementation Dampens Subjective and Objective Responses to Alcohol: Evidence From a Preclinical Rat Study and a Randomized, Cross-Over Trial in Healthy Volunteers

The International Journal of Neuropsychopharmacology(2024)10.1093/ijnp/pyae009

N/A

0DataRank · unranked

5 citations

Zhenhao Shi, Dustin R. Todaro, Timothy Pond, Juliana I. Byanyima, Sianneh A. Vesslee +9 more

Divergent gene expression patterns in alcohol and opioid use disorders lead to consistent alterations in functional networks within the dorsolateral prefrontal cortex

Translational Psychiatry(2024)10.1038/s41398-024-03143-z

N/A

0DataRank · unranked

4 citations

Pablo Augusto de Souza Fonseca, Kory Johnson, Erin M. Murray, Rachel L. Kember, Henry R. Kranzler +3 more

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

UNC Libraries(2024)10.17615/9206-yd08

N/A

0DataRank · unranked

4 citations

Scott Vrieze, Andrew D. Grotzinger, Dajiang J. Liu, Rachel L. Kember, Travis T. Mallard +24 more

Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample

medRxiv(2024)10.1101/2024.05.09.24307111

N/A

0DataRank · unranked

7 citations

Christal N. Davis, Zeal Jinwala, Kyra Feuer, Sylvanus Toikumo, Emily E. Hartwell +6 more

Multi-omic network analysis identifies dysregulated neurobiological pathways in opioid addiction

medRxiv(2024)10.1101/2024.01.04.24300831

N/A

0DataRank · unranked

1 citations

David Kainer, Matthew Lane, Mikaela Cashman, J Izaak Miller, Michael R. Garvin +23 more

Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.25.615046

N/A

0DataRank · unranked

1 citations

Sigurbjörn Markússon, Mikael Åkerlund, Justin C. Deme, Mandy Tseng, Wenqianglong Li +19 more

Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits

medRxiv(2024)10.1101/2024.01.22.24301615

Top 100%

0DataRank

Top 100%0 citations

Zeal Jinwala, Jackson Milone, Sarah Stewart de Ramirez, Joel Gelernter, Henry R. Kranzler +2 more

Heterogeneous associations between interleukin-6 receptor variants and phenotypes across ancestries and implications for therapy

Scientific Reports(2024)10.1038/s41598-024-54063-3

N/A

0DataRank · unranked

0 citations

Molei Liu, Isabelle-Emmanuella Nogues, Tony Chen, Xin Xiong, Clara-Lea Bonzel +89 more

A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.26.595949

Top 100%

0DataRank

Top 100%0 citations

Samar Nasser Chehimi, R. Merkel, Sylvanus Toikumo, Wade H. Berrettini, Henry R. Kranzler +5 more

Epigenetic and Genetic Profiling of Comorbidity Patterns among Substance Dependence Diagnoses

medRxiv(2024)10.1101/2024.10.08.24315111

N/A

0DataRank · unranked

0 citations

Robert H. Pietrzak, AnnMarie Lacobelle, Cassie Overstreet, Frank R. Wendt, Joseph D. Deak +8 more

An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy

Nature Genetics(2025)10.1038/s41588-025-02372-2

N/A

0DataRank · unranked

9 citations

Liam Gaziano, Zeina R. Al Sayed, Renae Judy, Laura M. Raffield, Kiran J. Biddinger +59 more

Transdiagnostic and Disorder-Level Genome-Wide Association Studies Enhance Precision of Substance Use and Psychiatric Genetic Risk Profiles in African and European Ancestries

Biological Psychiatry(2025)10.1016/j.biopsych.2025.04.021

N/A

0DataRank · unranked

7 citations

Christal N. Davis, Zeal Jinwala, Kyra Feuer, Sylvanus Toikumo, Emily E. Hartwell +6 more

The cell-type–specific genetic architecture of chronic pain in brain and dorsal root ganglia

Journal of Clinical Investigation(2025)10.1172/jci197583

N/A

0DataRank · unranked

4 citations

Marc Parisien, Michael J. Leone, Chaitanya Srinivasan, Huasheng Yu, Asta Arendt-Tranholm +12 more

Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits

Psychological Medicine(2025)10.1017/s0033291725100883

N/A

0DataRank · unranked

2 citations

Dongbing Lai, Jared V. Balbona, Alex P. Miller, Alexander S. Hatoum, Joseph D. Deak +62 more

The genetics of cannabis lifetime use

Neuropsychopharmacology(2025)10.1038/s41386-025-02255-4

N/A

0DataRank · unranked

2 citations

S L Beck, Marco Galimberti, Priya Gupta, Yu Chen, Cecilia Dao +8 more

Whole-exome sequencing study of opioid dependence offers novel insights into the contributions of exome variants

Translational Psychiatry(2025)10.1038/s41398-025-03578-y

N/A

0DataRank · unranked

2 citations

Yaira Z. Nuñez, José Jaime Martínez‐Magaña, Melody Rivera-Hernández, Zhongzheng Mao, Kristen Brennand +5 more

Communication-efficient federated learning of temporal effects on opioid use disorder with data from distributed research networks

Journal of the American Medical Informatics Association(2025)10.1093/jamia/ocae313

N/A

0DataRank · unranked

1 citations

Chongliang Luo, Henry R. Kranzler, Jiang Bian, Yong Chen, C Jason Liang

Genotype‐by‐sex interaction analyses for alcohol use disorder across biobanks

Alcohol Clinical and Experimental Research(2025)10.1111/acer.70173

N/A

0DataRank · unranked

1 citations

Lu Wang, Zhongzheng Mao, P. J. Michael Deans, Rachel L. Kember, Qingyu Chen +12 more

Gene discovery and pleiotropic architecture of Chronic Pain in a Genome-wide Association Study of >1.2 million Individuals

medRxiv(2025)10.1101/2025.02.28.25323112

N/A

0DataRank · unranked

5 citations

Christal N. Davis, Zeal Jinwala, Yousef Khan, Mariela Jennings, Lea K. Davis +4 more

A Randomized Controlled Trial of Cognitive Behavioral Therapy for Insomnia During Early Recovery from Alcohol Use Disorder Among Veterans

medRxiv(2025)10.1101/2025.01.03.25319973

N/A

0DataRank · unranked

3 citations

Knashawn H. Morales, Michael L. Perlis, Samuel T. Kuna, Sean He, David W. Oslin +3 more

Etiological basis for chronic pain genetic variation in brain and dorsal root ganglia cell types

medRxiv(2025)10.1101/2025.07.03.25330832

N/A

0DataRank · unranked

1 citations

Marc Parisien, Michael J. Leone, Chaitanya Srinivasan, Huasheng Yu, Asta Arendt-Tranholm +12 more

DNA Methylation Signatures of Alcohol Use Disorder – A large-scale Meta-Analysis in the Psychiatric Genomics Consortium

medRxiv(2025)10.1101/2025.08.29.25334705

N/A

0DataRank · unranked

1 citations

Sofia D'Augello, Diana Avetyan, Graciela Delgado, Ian R. Gizer, Jeesun Jung +39 more

Gene discovery and pleiotropic architecture of chronic pain in a genome-wide association study of >1.2 million individuals

Research Square(2025)10.21203/rs.3.rs-6173614/v1

N/A

0DataRank · unranked

0 citations

Sylvanus Toikumo, Christal N. Davis, Zeal Jinwala, Yousef Khan, Mariela Jennings +4 more

Polygenic risk and childhood adversity as moderators of drug and alcohol withdrawal symptoms

Drug and Alcohol Dependence(2025)10.1016/j.drugalcdep.2025.112712

N/A

0DataRank · unranked

0 citations

Christal N. Davis, Zeal Jinwala, Jackson F SooHoo, Joel Gelernter, Richard Feinn +2 more

Development and External Validation of a Genetic Risk Score for Pain in Rheumatoid Arthritis

Arthritis Care & Research(2025)10.1002/acr.25588

N/A

0DataRank · unranked

0 citations

Thomas R. Riley, Kristin Wipfler, Kaleb Michaud, Austin M. Wheeler, Bryant R. England +11 more

Multi-ancestry Genome-wide Association Study of Inpatient Opioid Dosing Following Knee or Hip Arthroplasty

medRxiv(2025)10.1101/2025.07.23.25331996

N/A

0DataRank · unranked

0 citations

Christal N. Davis, Jackson F SooHoo, Million Veteran Program, Penn Medicine BioBank, Joel Gelernter +4 more

Effect of smartphone breathalyzer feedback on willingness to drive in moderately intoxicated individuals: A randomized trial.

Psychology of Addictive Behaviors(2025)10.1037/adb0001088

N/A

0DataRank · unranked

0 citations

Henry R. Kranzler, Ian Barnett, Jessica Hemmons, Ruiqi Yan, Evan Spencer +2 more

Multi-ancestry Genome-wide Association Study of Inpatient Opioid Dosing Following Knee or Hip Arthroplasty

Research Square(2025)10.21203/rs.3.rs-7330342/v1

N/A

0DataRank · unranked

0 citations

Zeal Jinwala, Christal N. Davis, Jackson F SooHoo, Joel Gelernter, Rachel L. Kember +2 more

Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders

Psychiatry Research(2024)10.1016/j.psychres.2024.115758

N/A

0DataRank · unranked

17 citations

Marina Mitjans, Manuela R. Kouakou, Eleni Friligkou, Brenda Cabrera‐Mendoza, Joseph D. Deak +19 more

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

Molecular Psychiatry(2020)10.1038/s41380-020-0677-9

N/A

0DataRank · unranked

146 citations

Raymond K. Walters, Emma C. Johnson, Jeanette N. McClintick, Amy Adkins, Daniel E. Adkins +40 more

Identifying factors associated with opioid cessation in a biracial sample using machine learning

Exploration of Medicine(2020)10.37349/emed.2020.00003

N/A

0DataRank · unranked

7 citations

Richard Sherva, Kathryn L. Lunetta, Richard Saitz, Mark Kon, Henry R. Kranzler +3 more

Ancestry May Confound Genetic Machine Learning: Candidate-Gene Prediction of Opioid Use Disorder as an Example

medRxiv(2020)10.1101/2020.09.12.20193342

N/A

0DataRank · unranked

5 citations

Frank R. Wendt, Marco Galimberti, Renato Polimanti, Benjamin M. Neale, Henry R. Kranzler +4 more

Trauma and posttraumatic stress interact with sex-specific risk loci for suicidality and converge on brain extracellular matrix biology and synaptic plasticity

medRxiv(2020)10.1101/2020.05.18.20105734

N/A

0DataRank · unranked

3 citations

Gita A. Pathak, Daniel F. Levey, Yaira Z. Nuñez, Cassie Overstreet, Chelsea Tyrrell +11 more

Complex multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidal behaviors

medRxiv(2020)10.1101/2020.01.14.20017509

N/A

0DataRank · unranked

1 citations

Daniel F. Levey, Gita A. Pathak, Frank R. Wendt, Yaira Z. Nuñez, Robert J. Ursano +5 more

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

Nature Neuroscience(2021)10.1038/s41593-021-00908-3

N/A

0DataRank · unranked

332 citations

Travis T. Mallard, Peter B. Barr, Sandra Sanchez-Roige, James W. Madole, Morgan N. Driver +70 more

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

Biological Psychiatry(2021)10.1016/j.biopsych.2021.09.020

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0DataRank · unranked

69 citations

Karmel W. Choi, Jonathan R. I. Coleman, Nikolaos P. Daskalakis, Christy A. Denckla, Elizabeth Ketema +95 more

Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality

Neurobiology of Stress(2021)10.1016/j.ynstr.2021.100309

N/A

0DataRank · unranked

54 citations

Gita A. Pathak, Daniel F. Levey, Yaira Z. Nuñez, Cassie Overstreet, Chelsea Tyrrell +11 more

Nutritional Ketosis as a Potential Treatment for Alcohol Use Disorder

Frontiers in Psychiatry(2021)10.3389/fpsyt.2021.781668

N/A

0DataRank · unranked

34 citations

Sophie K. Elvig, Leandro F. Vendruscolo, George F. Koob, Valerie L. Darcey, Michael King +4 more

Multi-environment gene interactions linked to the interplay between polysubstance dependence and suicidality

Translational Psychiatry(2021)10.1038/s41398-020-01153-1

N/A

0DataRank · unranked

27 citations

Daniel F. Levey, Gita A. Pathak, Frank R. Wendt, Yaira Z. Nuñez, Robert J. Ursano +5 more

Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid Mechanisms

Circulation Genomic and Precision Medicine(2021)10.1161/circgen.120.003011

N/A

0DataRank · unranked

14 citations

Frank R. Wendt, Antonella De Lillo, Yaira Z. Nuñez, Aranyak Goswami, Flavio De Angelis +5 more

Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Exploration of Medicine(2021)10.37349/emed.2021.00032

N/A

0DataRank · unranked

19 citations

Congcong Zhu, Leah Wetherill, Howard J. Edenberg, Emma C. Johnson, Louisa Degenhardt +7 more

Examining a brief measure and observed cutoff scores to identify reward and relief drinking profiles: Psychometric properties and pharmacotherapy response

Drug and Alcohol Dependence(2021)10.1016/j.drugalcdep.2021.109257

N/A

0DataRank · unranked

19 citations

Karl Mann, Henry R. Kranzler, Corey R. Roos, Helmut Nakovics, Katie Witkiewitz +1 more

Genome-wide association study of stimulant dependence

Translational Psychiatry(2021)10.1038/s41398-021-01440-5

N/A

0DataRank · unranked

9 citations

Richard Sherva, Leah Wetherill, Tatiana Foroud, Howard J. Edenberg, Henry R. Kranzler +3 more

Antagonism of GluK1-containing kainate receptors reduces ethanol consumption by modulating ethanol reward and withdrawal

Neuropharmacology(2021)10.1016/j.neuropharm.2021.108783

N/A

0DataRank · unranked

7 citations

Erika E. Perez, Richard Feinn, Henry R. Kranzler, Mariella De Biasi, Natalia A. Quijano Cardé

Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Exploration of Medicine(2021)10.37349/emed.2020.00032

N/A

0DataRank · unranked

7 citations

Congcong Zhu, Leah Wetherill, Howard J. Edenberg, Emma C. Johnson, Louisa Degenhardt +7 more

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