Joseph Loscalzo

MedicineBiochemistry, Genetics and Molecular BiologyComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 7%percentile

0.165Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

De Novo exposomic geospatial assembly of chronic disease regions with machine learning & network analysis

EBioMedicine(2025)10.1016/j.ebiom.2025.105575

Top 70%

0.165DataRank

Top 70%2 citations

Ayushi Batwara, Roy Wada, Puneet Sharma, Joseph Loscalzo, Bisola O. Ojikutu +2 more

Papers

Driven by 70 papers — median percentile 0. Top paper: “Epigenetic Modifications: Basic Mechanisms and Role in Cardiovascular Disease (2013 Grover Conference Series)”.

Epigenetic Modifications: Basic Mechanisms and Role in Cardiovascular Disease (2013 Grover Conference Series)

Pulmonary Circulation(2014)10.1086/675979

N/A

4.4DataRank · unranked

164 citations

Diane E. Handy, Joseph Loscalzo

SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia

Brain(2023)10.1093/brain/awac460

N/A

0.992DataRank · unranked

35 citations

Hagar Mor Shaked, Kenneth Gable, Sita D. Gupta, Xueyang Pan, Niranjanakumari Somashekarappa +93 more

Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2025581118

N/A

0.942DataRank · unranked

534 citations

Ítalo Faria do Valle, Marinka Zitnik, Asher Ameli, Xiao Gan, Onur Varol +6 more

Molecular networks in Network Medicine: Development and applications

WIREs Systems Biology and Medicine(2020)10.1002/wsbm.1489

N/A

0.812DataRank · unranked

223 citations

Harald Schmidt, Eleni Anastasiadou, Lucia Altucci, Marco Angelini, Lina Badimón +21 more

The application of big data to cardiovascular disease: paths to precision medicine

Journal of Clinical Investigation(2020)10.1172/jci129203

N/A

0.704DataRank · unranked

108 citations

Bradley A. Maron, Joseph Loscalzo, Jane A. Leopold

Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine

Systems Medicine(2020)10.1089/sysm.2020.0001

N/A

0.696DataRank · unranked

12 citations

Ancha Baranova, Pat Baird, Elia Brodsky, Atul Janardhan Butte, Amrita K. Cheema +45 more

The inclusion of augmented intelligence in medicine: A framework for successful implementation

Cell Reports Medicine(2022)10.1016/j.xcrm.2021.100485

N/A

0.688DataRank · unranked

97 citations

Jennifer L. Hall, Joseph Loscalzo, Elliott M. Antman, Valentı́n Fuster, Antonis A. Armoundas +1 more

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Nature Communications(2023)10.1038/s41467-023-37079-7

N/A

0.584DataRank · unranked

48 citations

Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti +26 more

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Blood(2020)10.1182/blood.2019003940

N/A

0.571DataRank · unranked

44 citations

Chiqi Chen, Xiaoxin Hao, Ni Su, Dan Huang, Yejun Zou +16 more

Clinical sites of the Undiagnosed Diseases Network: unique contributions to genomic medicine and science

Genetics in Medicine(2020)10.1038/s41436-020-00984-z

N/A

0.564DataRank · unranked

42 citations

Cecilia Esteves, Anna Bican, Rebecca C. Spillmann, Heidi Cope, Allyn McConkie‐Rosell +89 more

ALDH7A1 protects against ferroptosis by generating membrane NADH and regulating FSP1

Cell(2025)10.1016/j.cell.2025.03.019

N/A

0.538DataRank · unranked

35 citations

Andrew Morris, Koki Kamizaki, Jianzhong Chen, Jillian Stark, William M. Oldham +8 more

Integration of circulating microRNAs and transcriptome signatures identifies early‐pregnancy biomarkers of preeclampsia

Clinical and Translational Medicine(2023)10.1002/ctm2.1446

N/A

0.453DataRank · unranked

11 citations

Diane E. Handy, Zheng Lü, Benjamin D. Oppenheimer, Augusto A. Litonjua, Joseph Loscalzo +2 more

Nitric oxide in vascular biology: elegance in complexity

Journal of Clinical Investigation(2024)10.1172/jci176747

N/A

0.434DataRank · unranked

17 citations

Joseph Loscalzo

Local generation and efficient evaluation of numerous drug combinations in a single sample

eLife(2023)10.7554/elife.85439

N/A

0.342DataRank · unranked

6 citations

Joseph Loscalzo, Vlad Elgart

Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome

Frontiers in Pain Research(2022)10.3389/fpain.2021.775386

N/A

0.312DataRank · unranked

7 citations

Anthony Lembo, Ted J. Kaptchuk, Vivian Cheng, Judy Nee, Johanna Iturrino +5 more

Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome

Frontiers in Psychiatry(2022)10.3389/fpsyt.2022.842030

N/A

0.292DataRank · unranked

6 citations

Rui‐Sheng Wang, Stephanie Regis, Hailey Yetman, Anthony Lembo, Ted J. Kaptchuk +7 more

Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2322582121

N/A

0.292DataRank · unranked

6 citations

Oguz Kanca, Rishi V. Shridharan, Paul C. Marcogliese, Benjamin Steger, Marie Morimoto +92 more

De Novo exposomic geospatial assembly of chronic disease regions with machine learning & network analysis

EBioMedicine(2025)10.1016/j.ebiom.2025.105575

Top 70%

0.165DataRank

Top 70%2 citations

Ayushi Batwara, Roy Wada, Puneet Sharma, Joseph Loscalzo, Bisola O. Ojikutu +2 more

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science(2025)10.1002/advs.202513641

N/A

0.165DataRank · unranked

2 citations

Yuxin Yang, W T Martin, Ko-Chow Lin, Zixu Wang, Cheng‐Chang Lu +6 more

A system perspective on drug response

British Journal of Pharmacology(2025)10.1111/bph.70128

N/A

0.104DataRank · unranked

1 citations

Joseph Loscalzo, Vlad Elgart

Assessment of community efforts to advance computational prediction of protein-protein interactions

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.22.461292

N/A

0DataRank · unranked

3 citations

Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti +25 more

Ultrasensitive sensors reveal the spatiotemporal landscape of lactate metabolism in physiology and disease

Cell Metabolism(2022)10.1016/j.cmet.2022.10.002

N/A

0DataRank · unranked

134 citations

Yinan Zhang, Lingyan Xu, Aoxue Wang, Yejun Zou, Ting Li +23 more

A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets

Genome Medicine(2022)10.1186/s13073-022-01048-4

N/A

0DataRank · unranked

63 citations

Eun Jung Lee, Sandra Lilja, Joseph Loscalzo, Samuel Schäfer, Martin Smelik +9 more

Molecular interaction networks and drug development: Novel approach to drug target identification and drug repositioning

The FASEB Journal(2022)10.1096/fj.202201683r

N/A

0DataRank · unranked

55 citations

Joseph Loscalzo

What Causes Hypertrophic Cardiomyopathy?

The American Journal of Cardiology(2022)10.1016/j.amjcard.2022.06.017

N/A

0DataRank · unranked

49 citations

Rui‐Sheng Wang, Mercedes R. Carnethon, Ethan J. Rowin, Joseph Loscalzo, Barry J. Maron +2 more

Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

iScience(2022)10.1016/j.isci.2022.104925

N/A

0DataRank · unranked

29 citations

Patrick T. Keiser, Deisy Morselli-Gysi, Giulia Menichetti, Hiroyuki Mori, Callie J. Donahue +21 more

Expression of CD70 Modulates Nitric Oxide and Redox Status in Endothelial Cells

Arteriosclerosis Thrombosis and Vascular Biology(2022)10.1161/atvbaha.122.317866

N/A

0DataRank · unranked

12 citations

Markus Waldeck‐Weiermair, Quinn S. Wells, Wusheng Xiao, Shambhu Yadav, Emrah Eroğlu +3 more

Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.21.521456

N/A

0DataRank · unranked

0 citations

Julius L. Decano, Joan T. Matamalas, Mary C. Whelan, Takaharu Asano, Namitra Kalicharran +4 more

Multiomics Network Medicine Approaches to Precision Medicine and Therapeutics in Cardiovascular Diseases

Arteriosclerosis Thrombosis and Vascular Biology(2023)10.1161/atvbaha.122.318731

N/A

0DataRank · unranked

96 citations

Bradley A. Maron, Joseph Loscalzo, Rui‐Sheng Wang

Cord blood DNA methylation signatures associated with preeclampsia are enriched for cardiovascular pathways: insights from the VDAART trial

EBioMedicine(2023)10.1016/j.ebiom.2023.104890

N/A

0DataRank · unranked

21 citations

Priyadarshini Kachroo, Iskander L.C. Shadid, Alireza Raissadati, Cheng Peng, Thomas F. McElrath +6 more

Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.100956

N/A

0DataRank · unranked

26 citations

Xinxiu Li, Martin Smelik, Eun Jung Lee, Joseph Loscalzo, Pratheek Bellur Marthanda +10 more

MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia

eLife(2023)10.7554/elife.82597

N/A

0DataRank · unranked

15 citations

Benjamin A. Olenchock, David R. Ziehr, Sarah McGarrity, Kevin Leahy, Jamey D. Young +3 more

Uncovering common pathobiological processes between COVID‐19 and pulmonary arterial hypertension by integrating Omics data

Pulmonary Circulation(2023)10.1002/pul2.12191

N/A

0DataRank · unranked

7 citations

Joseph Loscalzo, Rui‐Sheng Wang

High-dimensional immunophenotyping reveals immune cell aberrations in patients with undiagnosed inflammatory and autoimmune diseases

Journal of Clinical Investigation(2023)10.1172/jci169619

N/A

0DataRank · unranked

3 citations

Takanori Sasaki, Joshua Keegan, Jennifer P. Nguyen, Alec Griffith, Alice Horisberger +21 more

Data from: Local generation and efficient evaluation of numerous drug combinations in a single sample

DRYAD(2023)10.5061/dryad.76hdr7t1d

Top 100%

0DataRank

Top 100%0 citations

Vlad Elgart, Joseph Loscalzo

Decoding the Foodome: Molecular Networks Connecting Diet and Health

Annual Review of Nutrition(2024)10.1146/annurev-nutr-062322-030557

N/A

0DataRank · unranked

24 citations

Albert-László Barabási, Joseph Loscalzo, Giulia Menichetti

Branched-chain α-ketoacids aerobically activate HIF1α signalling in vascular cells

Nature Metabolism(2024)10.1038/s42255-024-01150-4

N/A

0DataRank · unranked

20 citations

Nishith Shrimali, Niv Vigder, William M. Oldham, Clary B. Clish, Huamei He +7 more

An interactive atlas of genomic, proteomic, and metabolomic biomarkers promotes the potential of proteins to predict complex diseases

Scientific Reports(2024)10.1038/s41598-024-63399-9

N/A

0DataRank · unranked

18 citations

Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Oleg Sysoev, Firoj Mahmud +3 more

Metabolic Responses to Redox Stress in Vascular Cells

Antioxidants and Redox Signaling(2024)10.1089/ars.2023.0476

N/A

0DataRank · unranked

8 citations

Laurel Yong-Hwa Lee, Joseph Loscalzo, Wusheng Xiao

Dominant missense variants in SREBF2 are associated with complex dermatological, neurological, and skeletal abnormalities

Genetics in Medicine(2024)10.1016/j.gim.2024.101174

N/A

0DataRank · unranked

4 citations

Kristhen N Atala, Yiming Zheng, Debdeep Dutta, Dorothy K. Grange, Wen‐Wen Lin +95 more

Multi-Omics and Single-Cell Omics: New Tools in Drug Target Discovery

Arteriosclerosis Thrombosis and Vascular Biology(2024)10.1161/atvbaha.124.320686

N/A

0DataRank · unranked

7 citations

Joseph Loscalzo

An interactive atlas of genomic, proteomic, and metabolomic biomarkers promotes the potential of proteins to predict complex diseases

Research Square(2024)10.21203/rs.3.rs-3921099/v1

Top 100%

0DataRank

Top 100%0 citations

Martin Smelik, Xinxiu Li, Joseph Loscalzo, Oleg Sysoev, Firoj Mahmud +3 more

DREAMER: Exploring Common Mechanisms of Adverse Drug Reactions and Disease Phenotypes through Network-Based Analysis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.20.602911

N/A

0DataRank · unranked

0 citations

Maria L. Elkjaer, Diane E. Handy, Rui‐Sheng Wang, Zoe Chervontseva, Matthias Rarey +4 more

Patient agency and large language models in worldwide encoding of equity

npj Digital Medicine(2025)10.1038/s41746-025-01598-y

N/A

0DataRank · unranked

12 citations

Joseph Loscalzo, Antonis A. Armoundas

Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery

Genome Medicine(2025)10.1186/s13073-025-01431-x

N/A

0DataRank · unranked

7 citations

Sarvesh Chelvanambi, Julius L. Decano, Joan T. Matamalas, Mary C. Whelan, Takaharu Asano +5 more

Network‐based precision medicine and systems pharmacology

British Journal of Pharmacology(2025)10.1111/bph.70184

N/A

0DataRank · unranked

6 citations

Susan Dina Ghiassian, Joseph Loscalzo, Arvind K. Pandey

Challenges and opportunities in the network medicine of complex diseases

Med(2025)10.1016/j.medj.2025.100920

N/A

0DataRank · unranked

5 citations

Joseph Loscalzo, Manlio De Domenico, Valeria d’Andrea

Exploring common mechanisms of adverse drug reactions and disease phenotypes through network-based analysis

Cell Reports Methods(2025)10.1016/j.crmeth.2025.100990

N/A

0DataRank · unranked

4 citations

Maria L. Elkjaer, Diane E. Handy, Rui‐Sheng Wang, Zoe Chervontseva, Matthias Rarey +4 more

Learning Universal Representations of Intermolecular Interactions with ATOMICA

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.02.646906

N/A

0DataRank · unranked

7 citations

Michael Desgagné, Zaixi Zhang, Xiao‐Hua Zhou, Joseph Loscalzo, Bradley L. Pentelute +2 more

NetMedPy: a Python package for large-scale network medicine screening

Bioinformatics(2025)10.1093/bioinformatics/btaf338

N/A

0DataRank · unranked

1 citations

Michael Sebek, Gordana Ispirova, Rodrigo Dorantes-Gilardi, Joseph Loscalzo, Albert-László Barabási +2 more

Network-Based Precision Medicine and Systems Pharmacology

(2025)10.22541/au.173892435.58103211/v1

N/A

0DataRank · unranked

0 citations

Susan Dina Ghiassian, Joseph Loscalzo, Arvind K. Pandey

Target identification among known drugs by deep learning from heterogeneous networks

Chemical Science(2020)10.1039/c9sc04336e

N/A

0DataRank · unranked

354 citations

Siyi Zhu, Weiqiang Lü, Zehui Liu, Jin Huang, Yadi Zhou +10 more

A systematic comprehensive longitudinal evaluation of dietary factors associated with acute myocardial infarction and fatal coronary heart disease

Nature Communications(2020)10.1038/s41467-020-19888-2

N/A

0DataRank · unranked

65 citations

Giulia Menichetti, Yanping Li, Joseph Loscalzo, Walter C. Willett, Albert-Ĺaszló Barabási +1 more

Importance of scientific collaboration in contemporary drug discovery and development: a detailed network analysis

BMC Biology(2020)10.1186/s12915-020-00868-3

N/A

0DataRank · unranked

36 citations

Yifang Ma, Brian Uzzi, Joseph Loscalzo, Feixiong Cheng

An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Genetics in Medicine(2020)10.1038/s41436-020-01027-3

N/A

0DataRank · unranked

49 citations

Kirsty McWalter, Heleen te Brinke, Lodewijk IJlst, Petra M. Mooijer, Jos P.N. Ruiter +95 more

Network medicine in Cardiovascular Research

Cardiovascular Research(2020)10.1093/cvr/cvaa321

N/A

0DataRank · unranked

39 citations

Arvind K. Pandey, Bradley A. Maron, Joseph Loscalzo, Laurel Yong-Hwa Lee

Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta

Scientific Reports(2020)10.1038/s41598-020-74100-1

N/A

0DataRank · unranked

24 citations

Enrico Maiorino, Vincent J. Carey, Thomas F. McElrath, Augusto A. Litonjua, Joseph Loscalzo +3 more

Network Medicine Framework Shows Proximity of Polyphenol Targets and Disease Proteins is Predictive of the Therapeutic Effects of Polyphenols

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.27.270173

N/A

0DataRank · unranked

4 citations

Harvey G. Roweth, Michael W. Malloy, Sofia Moco, Denís Barron, Elisabeth M. Battinelli +3 more

MYC overrides HIF to regulate proliferating primary cell metabolism in hypoxia

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.21.306464

N/A

0DataRank · unranked

1 citations

Benjamin A. Olenchock, David R. Ziehr, Sarah McGarrity, Kevin Leahy, Jamey D. Young +3 more

Comprehensive characterization of protein-protein interaction network perturbations by human disease mutations

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.18.302588

N/A

0DataRank · unranked

0 citations

Junfei Zhao, Yang Wang, Weiqiang Lü, Zehui Liu, Yadi Zhou +19 more

Interferon-γ Impairs Human Coronary Artery Endothelial Glucose Metabolism by Tryptophan Catabolism and Activates Fatty Acid Oxidation

Circulation(2021)10.1161/circulationaha.121.053960

N/A

0DataRank · unranked

106 citations

William M. Oldham, Huamei He, Ruisheng Wang, Ryan Mulhern, Diane E. Handy +2 more

Immunometabolic Endothelial Phenotypes: Integrating Inflammation and Glucose Metabolism

Circulation Research(2021)10.1161/circresaha.120.318805

N/A

0DataRank · unranked

103 citations

William M. Oldham, Carmen Priolo, Arvind K. Pandey, Joseph Loscalzo, Wusheng Xiao

Selenium, a Micronutrient That Modulates Cardiovascular Health via Redox Enzymology

Nutrients(2021)10.3390/nu13093238

N/A

0DataRank · unranked

102 citations

Jacob Joseph, Joseph Loscalzo, Diane E. Handy

Gene co-expression in the interactome: moving from correlation toward causation via an integrated approach to disease module discovery

npj Systems Biology and Applications(2021)10.1038/s41540-020-00168-0

N/A

0DataRank · unranked

92 citations

Giulia Fiscon, Federica Conte, Rui‐Sheng Wang, Lorenzo Farina, Joseph Loscalzo +1 more

Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes

Nature Communications(2021)10.1038/s41467-021-21146-y

N/A

0DataRank · unranked

92 citations

Rui‐Sheng Wang, Sergei Shevtsov, Stavros G. Drakos, Elena Arons, Omar Wever‐Pinzon +10 more

Temporal bias in case-control design: preventing reliable predictions of the future

Nature Communications(2021)10.1038/s41467-021-21390-2

N/A

0DataRank · unranked

88 citations

Brett K. Beaulieu‐Jones, Kun‐Hsing Yu, Scott L. Lipnick, Nathan Palmer, Joseph Loscalzo +3 more

NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification

Journal of the American College of Cardiology(2021)10.1016/j.jacc.2021.02.056

N/A

0DataRank · unranked

20 citations

Anna R. Hemnes, Micheala A. Aldred, John Barnard, Evan L. Brittain, Stephen Y. Chan +26 more

Superior Mesenteric Artery Dissection

JACC Case Reports(2021)10.1016/j.jaccas.2020.12.034

N/A

0DataRank · unranked

5 citations

Martin Solomon, Joseph Loscalzo, Ersilia M. DeFilippis

An overview of the process, progress, and outcomes of a National Center for Accelerated Innovation: The Boston Biomedical Innovation Center Experience

Journal of Clinical and Translational Science(2021)10.1017/cts.2021.791

N/A

0DataRank · unranked

1 citations

Mason W. Freeman, David E. Golan, Roger Kitterman, Erin McKenna, John A. Parrish +4 more

Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.20.440626

N/A

0DataRank · unranked

9 citations

Patrick T. Keiser, Deisy Morselli Gysi, Giulia Menichetti, Hiroyuki Mori, Callie J. Donahue +21 more

Joseph Loscalzo

Indexed papers

Top data-sharing exemplar

Papers