David M. Sabatini

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 30 papers. Top paper: “APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia”.

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia

Science Translational Medicine(2021)10.1126/scitranslmed.aaz4564

N/A

0.862DataRank · unranked

312 citations

Priyanka Narayan, Julia Maeve Bonner, Nora Kory, Sebastian Boland, Aleksandra A. Arczewska +14 more

Limited Environmental Serine Confers Sensitivity to PHGDH Inhibition in Brain Metastasis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.03.974980

N/A

0.104DataRank · unranked

1 citations

Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Alba Luengo +30 more

A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion

Cell Metabolism(2020)10.1016/j.cmet.2020.04.004

N/A

0DataRank · unranked

136 citations

Andrew L. Cangelosi, Jeffrey C. Davis, Quan Pham, Arielle Rothman, Aubrey L. Faust +4 more

A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance

Nature Medicine(2020)10.1038/s41591-019-0730-x

N/A

0DataRank · unranked

75 citations

Daniel T. Montoro, Hui Min Leung, Jason Yang, Hanan E. Shamseldin, Martin S. Taylor +16 more

A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells

iScience(2020)10.1016/j.isci.2020.101109

N/A

0DataRank · unranked

57 citations

Elizabeth A. Boydston, Emily Shortt, Gregory A. Wyant, Sebastian Lourido, Walter W. Chen +2 more

Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species

Science Advances(2020)10.1126/sciadv.abb7272

N/A

0DataRank · unranked

57 citations

Colleen R. Reczek, Gregory S. McElroy, Elizabeth M. Steinert, Timothy C. Wang, David M. Sabatini +2 more

ATRAID regulates the action of nitrogen-containing bisphosphonates on bone

Science Translational Medicine(2020)10.1126/scitranslmed.aav9166

N/A

0DataRank · unranked

25 citations

Damon T. Burrow, Jinmei Li, Jiwoong Park, Sandeep Kumar, Cheng Lyu +33 more

Dihydroxyacetone phosphate signals glucose availability to mTORC1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.21.161927

N/A

0DataRank · unranked

25 citations

Patrycja A. Krawczyk, Sonia M. Scaria, Andrew L. Cangelosi, Sze Ham Chan, Tenzin Kunchok +3 more

CRISPR screens in physiologic medium reveal conditionally essential genes in human cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.31.275107

N/A

0DataRank · unranked

15 citations

Kimberly S. Huggler, Charles H. Adelmann, Heather R. Keys, Ross Soens, David M. Sabatini +2 more

Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.22.351361

N/A

0DataRank · unranked

15 citations

Jose M. Orozco, Charles H. Adelmann, Jessica B. Spinelli, Pim W. van der Helm, Justin M. Roberts +3 more

Lysosomal nucleotide metabolism regulates ER proteostasis through mTOR signaling

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.18.048561

N/A

0DataRank · unranked

9 citations

Qian Zhao, Pei-Wen Hu, Chi-Lam Au-Yeung, Jin Yang, Lita Duraine +6 more

A PEROXO-Tag enables rapid isolation of peroxisomes from human cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.10.984948

N/A

0DataRank · unranked

5 citations

Elizabeth A. Boydston, Emily Shortt, Gregory A. Wyant, Sebastian Lourido, Walter W. Chen +2 more

MCART1 is required for mitochondrial NAD transport

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.28.267252

N/A

0DataRank · unranked

0 citations

Jelmi uit de Bos, Sanne van der Rijt, Nevena Jankovic, Miriam A. Güra, Nicholas L. Arp +7 more

CRISPR screens in physiologic medium reveal conditionally essential genes in human cells

Cell Metabolism(2021)10.1016/j.cmet.2021.02.005

N/A

0DataRank · unranked

152 citations

Kimberly S. Huggler, Charles H. Adelmann, Heather R. Keys, Ross Soens, David M. Sabatini +2 more

Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2022120118

N/A

0DataRank · unranked

131 citations

Jose M. Orozco, Charles H. Adelmann, Jessica B. Spinelli, Pim W. van der Helm, Justin M. Roberts +3 more

GCN2 adapts protein synthesis to scavenging-dependent growth

Cell Systems(2021)10.1016/j.cels.2021.09.014

N/A

0DataRank · unranked

35 citations

Timothy C. Wang, Lifeng Yang, Connor S.R. Jankowski, Hsin‐Jung Li, Seunghun Han +8 more

Co-deletion of ATAD1 with PTEN primes cells for BIM-mediated apoptosis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.01.450781

N/A

0DataRank · unranked

5 citations

Heidi L. Fresenius, Heather R. Keys, Corey N. Cunningham, Jeremy Ryan, Deepika Sirohi +9 more

CLN3 is required for the clearance of glycerophosphodiesters from lysosomes

Nature(2022)10.1038/s41586-022-05221-y

N/A

0DataRank · unranked

140 citations

Wentao Dong, Uche N. Medoh, Andrew L. Cangelosi, Vimisha Dharamdasani, Sze Ham Chan +11 more

Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine

Science(2022)10.1126/science.abi9547

N/A

0DataRank · unranked

74 citations

Anna M. Puszynska, Justin M. Roberts, Andrea Armani, Thao P. Nguyen, Jessica B. Spinelli +9 more

Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila

Nature(2022)10.1038/s41586-022-04960-2

N/A

0DataRank · unranked

59 citations

Patrick Jouandin, Pranav V. Lalgudi, Rich Binari, Max L. Valenstein, Michael A. Reid +6 more

Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction

eLife(2022)10.7554/elife.82860

N/A

0DataRank · unranked

20 citations

Heidi L. Fresenius, Corey N. Cunningham, Peng Wei, Heather R. Keys, Jordan A. Berg +12 more

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.16.512400

N/A

0DataRank · unranked

2 citations

Shihong Max Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jiaming Liu +7 more

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

eLife(2024)10.7554/elife.85214

N/A

0DataRank · unranked

33 citations

Shihong Max Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jiaming Liu +7 more

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Nature Communications(2024)10.1038/s41467-024-46680-3

N/A

0DataRank · unranked

29 citations

Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini, Grace Y. Liu

Rag–Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2322755121

N/A

0DataRank · unranked

23 citations

Pranav V. Lalgudi, Xin Gu, Jibril F. Kedir, Martin S. Taylor, Raghu R. Chivukula +2 more

Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.10.588849

N/A

0DataRank · unranked

6 citations

Melanie J. Mittenbühler, Yizhi Sun, Jonathan G. Van Vranken, Sebastian Schindler, Abhilash Jayaraj +21 more

Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST

Cell Metabolism(2025)10.1016/j.cmet.2025.01.024

N/A

0DataRank · unranked

45 citations

Melanie J. Mittenbühler, Yizhi Sun, Jonathan G. Van Vranken, Sebastian Schindler, Abhilash Jayaraj +23 more

Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders

Science(2025)10.1126/science.ado2403

N/A

0DataRank · unranked

9 citations

Yunhan Xu, David R. Ziehr, Martin S. Taylor, Max L. Valenstein, Evgeni M. Frenkel +11 more

SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation

Nature Communications(2025)10.1038/s41467-025-56130-3

N/A

0DataRank · unranked

12 citations

Ju Shi, Sarah Chang, Jason Yang, Samuel Block, Charles H. Adelmann +12 more

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

Cancer Discovery(2020)10.1158/2159-8290.cd-19-1228

N/A

0DataRank · unranked

287 citations

Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J. Liang +35 more